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The map label for this gene is recG [H]

Identifier: 78065288

GI number: 78065288

Start: 708450

End: 710783

Strand: Direct

Name: recG [H]

Synonym: Bcep18194_A3812

Alternate gene names: 78065288

Gene position: 708450-710783 (Clockwise)

Preceding gene: 78065281

Following gene: 78065289

Centisome position: 19.18

GC content: 70.48

Gene sequence:

>2334_bases
ATGCCTGTGTCACCACGCCGTTCCCCCGCTGCCGTTGCCGATTCCGCCGATCCGTTCGACGCGGAGGATGTCGCGCTACC
CGCGCAAAGCGCGGGGGAGCGTGGTTCCGCGGAGCGTGCCGCACCGCGCCGCGCCGGCCCGAAGCGTGGCGCCGACGGCA
GGCTCGCGCAGCCGGCCGCTGCAGCGCCCGATGCCGATGCCGATGACGTCGCGAGCGACGCAGCAGGTGCGGCCGGTGCG
AAGCGCAAGAAGAAGCCGGCTGCCGACAAACCGGTGAAGACCGTCGACAAGCTCGCGAAGCTCGGCCTCACGCGCTCGAT
CGATCTCGTGCTGCATCTGCCGATGCGCTACGAGGACGAAACCACGCTCACGCCGATCGGCGAGCTGCTGCCGGGCGGCA
TCGCGCAAGCCGAAGGCGTCGTGTTCGACAACGAGGTCGCGTACCGGCCGCGCCGCCAGCTGGTCGTGAAGATCCAGGAC
GACGACGGCGAGCACCTCGTGCTGCGCTTCCTGAATTTCTACGGCTCGCAGGTCAAGCAGATGGCTGTCGGCCAGCGCCT
GCGCGTGCGCGGCGACGTGCGCGGCGGCTTCTTCGGGATGGAGATGGTGCATCCGGCGGTGCGCGTCGTCGAAGCCGATG
CGCCGCTGCCGCAGGTGCTCACGCCCGTCTATCCGAGCACGGCCGGCGTGTCGCAGGCCTATCTGCGCAAGGCGATCGAG
AACGCGGTCGAGCGCACGCCACTGCCCGAGCTGCTGCCGCCCGAGATCCAGCGTGACTACCTGAAGCCGCTCGACGTGCC
GACGCTCGAGCAGGCAGTGCGCATCCTGCACCACCCGCGTGTCGATTCCGACGAAGCTGCGCTGATGGACGGCTCGCATC
CGGCGTGGACGCGCATCAAGTTCGAGGAATTGCTCGCGCAGCAGCTGTCGCTCAAGCGCGCGCACGAGGAGCGCCGCACA
CGCGCGGCGCCTGCGATGCCGCGCCGCACCGCGACCGATGCCGATTCACTGACGACGCGGCTCTATGGCGCGCTGCCGTT
CACGCTGACGGGCGCGCAGGCACGGGTCGTCGACGAAATCGCAAATGACCTCACGCTCGCGCACCCGATGCAGCGCCTGC
TGCAGGGTGATGTCGGCAGCGGCAAGACCGTCGTCGCGGCACTGGCCGCCACGCAGGCGATCGACGCCGGCTACCAGGCC
GCGCTGATGGCGCCCACCGAAATCCTCGCGGAACAGCACGCGCGCAAGCTGCGCGCGTGGCTCGAGCCGCTCGGCGTCAC
GGTCGCGTGGCTCGCGGGCAGCCTGAAGGCGAAGGAGAAGCGCGCGGCGATCGAGGCGGCCGCGCTCGGCACCGCGCAGC
TCGTGATCGGCACGCACGCGATCATCCAGGACACGGTTGAATTCGCGCGGCTCGGCCTCGTGATCGTCGACGAGCAGCAC
CGCTTCGGCGTCGAGCAGCGCCTCGCGCTGCGTGCGAAGGCCGCGAATGCGGCCAACGGCGCGCGCGACTTCCAGCCGCA
CCAGTTGATGATGTCGGCCACGCCGATTCCGCGCACGCTCGCGATGACGTATTACGCCGATCTCGAAGTCTCGACGATCG
ACGAGCTGCCGCCGGGCCGCACGCCCGTGCTGACACGCCTCGTCGGCGATGCGCGGCGCGAGGAGGTGATCGCCCGCGTG
CGCGAGGCCGCGCTGACCGGGCGCCAGGTGTACTGGGTGTGCCCGCTGATCGAGGAGAGCGAGACGCTGCAGTTGCAGAC
GGCCGTCGAAACCTACGAGACGCTGGCCACCGCGCTCCCGGAGCTGAAGGTCGGGCTGGTGCACGGCCGGCTGTCGCCGG
CCGACAAGGCGGCCGTGATGGAAGCGTTCACGCGCAACGACGTGCAGCTGCTCGTCGCGACGACGGTGATCGAGGTCGGC
GTCGACGTGCCGAACGCGTCGCTGATGGTGATCGAGCACGCGGAGCGTTTCGGCCTCGCACAGCTGCACCAGTTGCGCGG
CCGGGTCGGGCGCGGCACCGCGGCGTCGGTGTGCGTGCTGCTGTACACGGGGCCGCTGTCGCTCACGGGCCGCGAGCGGC
TGAAGACGATGCGCGAGACGACCGACGGCTTCGAGATCGCACGGCGCGATCTCGAGATCCGCGGCCCCGGCGAATTCCTC
GGCGCCCGCCAGTCGGGCGCGGCGATGCTGCGCTTCGCGAACCTCGAGACTGACGGCTGGCTGATCGATCCGGCCCGCGA
CGCCGCGACGCGGCTGATTGCCGCGTATCCCGAGATCGTCACGCAGCATCTCGCGCGCTGGCTCGGCGCGCGGGAGCAGT
ATCTGAAGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTATGATGACGGGATGCGCGGCCTGGCCGGCGTCGTTCGTTCGGACGACGTGAAAGCCGCTATTGTACTTGCCTTG
CGAAGCACCCAGACGATCCG

Downstream 100 bases:

>100_bases
TCCGCGGGTCGGGGCCGGATTTAAAACCGCCGTTTGAAGCATTCCGATGCAGAGAAACTTGGCGAACCGGTGTCACAGGG
TGTATAAATTAAACCTATCG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MPVSPRRSPAAVADSADPFDAEDVALPAQSAGERGSAERAAPRRAGPKRGADGRLAQPAAAAPDADADDVASDAAGAAGA
KRKKKPAADKPVKTVDKLAKLGLTRSIDLVLHLPMRYEDETTLTPIGELLPGGIAQAEGVVFDNEVAYRPRRQLVVKIQD
DDGEHLVLRFLNFYGSQVKQMAVGQRLRVRGDVRGGFFGMEMVHPAVRVVEADAPLPQVLTPVYPSTAGVSQAYLRKAIE
NAVERTPLPELLPPEIQRDYLKPLDVPTLEQAVRILHHPRVDSDEAALMDGSHPAWTRIKFEELLAQQLSLKRAHEERRT
RAAPAMPRRTATDADSLTTRLYGALPFTLTGAQARVVDEIANDLTLAHPMQRLLQGDVGSGKTVVAALAATQAIDAGYQA
ALMAPTEILAEQHARKLRAWLEPLGVTVAWLAGSLKAKEKRAAIEAAALGTAQLVIGTHAIIQDTVEFARLGLVIVDEQH
RFGVEQRLALRAKAANAANGARDFQPHQLMMSATPIPRTLAMTYYADLEVSTIDELPPGRTPVLTRLVGDARREEVIARV
REAALTGRQVYWVCPLIEESETLQLQTAVETYETLATALPELKVGLVHGRLSPADKAAVMEAFTRNDVQLLVATTVIEVG
VDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAASVCVLLYTGPLSLTGRERLKTMRETTDGFEIARRDLEIRGPGEFL
GARQSGAAMLRFANLETDGWLIDPARDAATRLIAAYPEIVTQHLARWLGAREQYLKA

Sequences:

>Translated_777_residues
MPVSPRRSPAAVADSADPFDAEDVALPAQSAGERGSAERAAPRRAGPKRGADGRLAQPAAAAPDADADDVASDAAGAAGA
KRKKKPAADKPVKTVDKLAKLGLTRSIDLVLHLPMRYEDETTLTPIGELLPGGIAQAEGVVFDNEVAYRPRRQLVVKIQD
DDGEHLVLRFLNFYGSQVKQMAVGQRLRVRGDVRGGFFGMEMVHPAVRVVEADAPLPQVLTPVYPSTAGVSQAYLRKAIE
NAVERTPLPELLPPEIQRDYLKPLDVPTLEQAVRILHHPRVDSDEAALMDGSHPAWTRIKFEELLAQQLSLKRAHEERRT
RAAPAMPRRTATDADSLTTRLYGALPFTLTGAQARVVDEIANDLTLAHPMQRLLQGDVGSGKTVVAALAATQAIDAGYQA
ALMAPTEILAEQHARKLRAWLEPLGVTVAWLAGSLKAKEKRAAIEAAALGTAQLVIGTHAIIQDTVEFARLGLVIVDEQH
RFGVEQRLALRAKAANAANGARDFQPHQLMMSATPIPRTLAMTYYADLEVSTIDELPPGRTPVLTRLVGDARREEVIARV
REAALTGRQVYWVCPLIEESETLQLQTAVETYETLATALPELKVGLVHGRLSPADKAAVMEAFTRNDVQLLVATTVIEVG
VDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAASVCVLLYTGPLSLTGRERLKTMRETTDGFEIARRDLEIRGPGEFL
GARQSGAAMLRFANLETDGWLIDPARDAATRLIAAYPEIVTQHLARWLGAREQYLKA
>Mature_776_residues
PVSPRRSPAAVADSADPFDAEDVALPAQSAGERGSAERAAPRRAGPKRGADGRLAQPAAAAPDADADDVASDAAGAAGAK
RKKKPAADKPVKTVDKLAKLGLTRSIDLVLHLPMRYEDETTLTPIGELLPGGIAQAEGVVFDNEVAYRPRRQLVVKIQDD
DGEHLVLRFLNFYGSQVKQMAVGQRLRVRGDVRGGFFGMEMVHPAVRVVEADAPLPQVLTPVYPSTAGVSQAYLRKAIEN
AVERTPLPELLPPEIQRDYLKPLDVPTLEQAVRILHHPRVDSDEAALMDGSHPAWTRIKFEELLAQQLSLKRAHEERRTR
AAPAMPRRTATDADSLTTRLYGALPFTLTGAQARVVDEIANDLTLAHPMQRLLQGDVGSGKTVVAALAATQAIDAGYQAA
LMAPTEILAEQHARKLRAWLEPLGVTVAWLAGSLKAKEKRAAIEAAALGTAQLVIGTHAIIQDTVEFARLGLVIVDEQHR
FGVEQRLALRAKAANAANGARDFQPHQLMMSATPIPRTLAMTYYADLEVSTIDELPPGRTPVLTRLVGDARREEVIARVR
EAALTGRQVYWVCPLIEESETLQLQTAVETYETLATALPELKVGLVHGRLSPADKAAVMEAFTRNDVQLLVATTVIEVGV
DVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAASVCVLLYTGPLSLTGRERLKTMRETTDGFEIARRDLEIRGPGEFLG
ARQSGAAMLRFANLETDGWLIDPARDAATRLIAAYPEIVTQHLARWLGAREQYLKA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=52.5325615050651, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=393, Percent_Identity=38.1679389312977, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 84301; Mature: 84169

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSPRRSPAAVADSADPFDAEDVALPAQSAGERGSAERAAPRRAGPKRGADGRLAQPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
AAPDADADDVASDAAGAAGAKRKKKPAADKPVKTVDKLAKLGLTRSIDLVLHLPMRYEDE
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TTLTPIGELLPGGIAQAEGVVFDNEVAYRPRRQLVVKIQDDDGEHLVLRFLNFYGSQVKQ
CCCCCHHHHCCCCCHHCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
MAVGQRLRVRGDVRGGFFGMEMVHPAVRVVEADAPLPQVLTPVYPSTAGVSQAYLRKAIE
HHHCCHHEEEECCCCCCHHHHHHHHHHHEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHH
NAVERTPLPELLPPEIQRDYLKPLDVPTLEQAVRILHHPRVDSDEAALMDGSHPAWTRIK
HHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHH
FEELLAQQLSLKRAHEERRTRAAPAMPRRTATDADSLTTRLYGALPFTLTGAQARVVDEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHH
ANDLTLAHPMQRLLQGDVGSGKTVVAALAATQAIDAGYQAALMAPTEILAEQHARKLRAW
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHH
LEPLGVTVAWLAGSLKAKEKRAAIEAAALGTAQLVIGTHAIIQDTVEFARLGLVIVDEQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEECHH
RFGVEQRLALRAKAANAANGARDFQPHQLMMSATPIPRTLAMTYYADLEVSTIDELPPGR
HCCHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCHHHEEEEEECCEEEHHHCCCCCC
TPVLTRLVGDARREEVIARVREAALTGRQVYWVCPLIEESETLQLQTAVETYETLATALP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEECCCCCEEHHHHHHHHHHHHHHCC
ELKVGLVHGRLSPADKAAVMEAFTRNDVQLLVATTVIEVGVDVPNASLMVIEHAERFGLA
HHHEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHH
QLHQLRGRVGRGTAASVCVLLYTGPLSLTGRERLKTMRETTDGFEIARRDLEIRGPGEFL
HHHHHHHCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHCCEECCCHHHH
GARQSGAAMLRFANLETDGWLIDPARDAATRLIAAYPEIVTQHLARWLGAREQYLKA
CCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
PVSPRRSPAAVADSADPFDAEDVALPAQSAGERGSAERAAPRRAGPKRGADGRLAQPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
AAPDADADDVASDAAGAAGAKRKKKPAADKPVKTVDKLAKLGLTRSIDLVLHLPMRYEDE
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TTLTPIGELLPGGIAQAEGVVFDNEVAYRPRRQLVVKIQDDDGEHLVLRFLNFYGSQVKQ
CCCCCHHHHCCCCCHHCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
MAVGQRLRVRGDVRGGFFGMEMVHPAVRVVEADAPLPQVLTPVYPSTAGVSQAYLRKAIE
HHHCCHHEEEECCCCCCHHHHHHHHHHHEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHH
NAVERTPLPELLPPEIQRDYLKPLDVPTLEQAVRILHHPRVDSDEAALMDGSHPAWTRIK
HHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHH
FEELLAQQLSLKRAHEERRTRAAPAMPRRTATDADSLTTRLYGALPFTLTGAQARVVDEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHH
ANDLTLAHPMQRLLQGDVGSGKTVVAALAATQAIDAGYQAALMAPTEILAEQHARKLRAW
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHH
LEPLGVTVAWLAGSLKAKEKRAAIEAAALGTAQLVIGTHAIIQDTVEFARLGLVIVDEQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEECHH
RFGVEQRLALRAKAANAANGARDFQPHQLMMSATPIPRTLAMTYYADLEVSTIDELPPGR
HCCHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCHHHEEEEEECCEEEHHHCCCCCC
TPVLTRLVGDARREEVIARVREAALTGRQVYWVCPLIEESETLQLQTAVETYETLATALP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEECCCCCEEHHHHHHHHHHHHHHCC
ELKVGLVHGRLSPADKAAVMEAFTRNDVQLLVATTVIEVGVDVPNASLMVIEHAERFGLA
HHHEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHH
QLHQLRGRVGRGTAASVCVLLYTGPLSLTGRERLKTMRETTDGFEIARRDLEIRGPGEFL
HHHHHHHCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHCCEECCCHHHH
GARQSGAAMLRFANLETDGWLIDPARDAATRLIAAYPEIVTQHLARWLGAREQYLKA
CCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]