Click here to switch to the map view.

The map label for this gene is ruvC

Identifier: 78065252

GI number: 78065252

Start: 671045

End: 671587

Strand: Reverse

Name: ruvC

Synonym: Bcep18194_A3776

Alternate gene names: 78065252

Gene position: 671587-671045 (Counterclockwise)

Preceding gene: 78065253

Following gene: 78065251

Centisome position: 18.18

GC content: 70.72

Gene sequence:

>543_bases
ATGCGAATTCTCGGCATCGACCCCGGCCTGCGCGTCACCGGCTTCGGCATCATCGACGTCAGCGGCCACCGGCTCGCGTA
TGTTGCGAGCGGCGTGATCCGCACGCCGACCGCCGACCTGGCCACCCGGCTCGGTACGATCTTCCAGGGCGTCTCGACCA
TCGTGCGCGAGCACGCCCCCGACCAGTCCGCGATCGAAAAGGTGTTCGTCAACGTGAACCCGCAGTCGACGCTGCTGCTC
GGCCAGGCGCGCGGCGCCGCGATCTGCGGCCTCGTCGCGGGCGGCCTGCCCGTTGCCGAATACACGGCGCTGCAGCTCAA
GCAGGCGGTGGTCGGCTACGGCCGCGCGACCAAGACGCAGATGCAGGAAATGGTCACGCGCCTGCTCAATCTCTCCGGAC
AACCGGGCTCCGACGCGGCCGATGCACTCGGCATGGCGATCTGCCACGCGCACGGCGGCAACACGCTCAGCACGCTCGGC
GGCCTCGCGCCGGCGCTCGCGAAGAAAGGGCTGCGCGTGCGGCGCGGGCGGCTGGTCGGCTGA

Upstream 100 bases:

>100_bases
GCCGGGTTTTTTATTGCGCGGCGCCCTCGTACGCGACCGTGCGGCCGGCACGCCGCACCATTCGTTGTAGTATCGCTGCA
TCAGGCTTTTCTCCTTACCC

Downstream 100 bases:

>100_bases
CACCGGCGCGCGCCCTCACGCGGCACGCCGGCTCGGCCGCGGTGCCTGAGCGCGTCGCACACGCGACGTACATCGCCCCG
GCCGGATGGCCGACTCCGTC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAPDQSAIEKVFVNVNPQSTLLL
GQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLG
GLAPALAKKGLRVRRGRLVG

Sequences:

>Translated_180_residues
MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAPDQSAIEKVFVNVNPQSTLLL
GQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLG
GLAPALAKKGLRVRRGRLVG
>Mature_180_residues
MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAPDQSAIEKVFVNVNPQSTLLL
GQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLG
GLAPALAKKGLRVRRGRLVG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=176, Percent_Identity=49.4318181818182, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18605; Mature: 18605

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAP
CEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DQSAIEKVFVNVNPQSTLLLGQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQ
CHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHH
MQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLGGLAPALAKKGLRVRRGRLVG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAP
CEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DQSAIEKVFVNVNPQSTLLLGQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQ
CHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHH
MQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLGGLAPALAKKGLRVRRGRLVG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA