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The map label for this gene is tkt1 [H]

Identifier: 78065198

GI number: 78065198

Start: 610203

End: 612275

Strand: Direct

Name: tkt1 [H]

Synonym: Bcep18194_A3722

Alternate gene names: 78065198

Gene position: 610203-612275 (Clockwise)

Preceding gene: 78065194

Following gene: 78065199

Centisome position: 16.52

GC content: 66.86

Gene sequence:

>2073_bases
ATGCCGCCGTGCCCCCGTTTCCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACCCTGAT
GGCCAACGCGATCCGTGCGCTCGCAATGGACGCCGTCCAGCAAGCGAACTCCGGCCACCCCGGCATGCCGATGGGCATGG
CCGAAATCGGCGTCGCGCTCTGGTCGCGCCATCTGAAGCACAACCCGACGAACCCGCACTGGGCGGACCGCGACCGCTTC
GTGCTGTCGAACGGCCATGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACCGGCTACGACCTGCCGATGGAAGAGCT
GAAGAACTTCCGCCAGCTGCACTCGAAGACGCCGGGCCACCCGGAATACGGCATCACGCCGGGCGTCGAGACGACCACCG
GCCCGCTCGGCCAGGGGCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAAGCGCTGATGGCCGACGAGTTCAACCGCGAC
GGCGCGAAGATCGTCGATCACCACACGTACGTGTTCCTCGGCGACGGCTGCCTGATGGAAGGCATCTCGCACGAAGCCTG
CTCGCTCGCCGGCACGCTGAAGCTGAACAAGCTGATCGCGCTGTACGACGACAACGGCATCTCGATCGACGGCGACGTCG
TGAACTGGTTCCACGACGACACCCCGAAGCGTTTCGAAGCCTACGGCTGGAACGTGATCCCGCACGTGAACGGCCATGAC
GTCGACGCGGTCGACGCAGCCATCGCAAAGGCGAAGCTGTCGGACAAGCCGACGCTGATCTGCTGCAAGACGGTGATCGG
CCAGGGCGCGGCGACCAAGGCCGGCGGCCACGACGTGCACGGCGCGGCGCTCGGCGCGGAAGAAATCGCGAAGACGCGCG
AAGCGCTCGGCTGGACGTGGGCACCGTTCGTGATTCCGCAGGAAGTCTATGCGGCATGGGACGCGAAGGAAGCCGGCAAG
CGCGCGGAAACCGAATGGGATGCGACGTTCGCTGCTTATCGCGCCAAGTTCCCGGCAGAAGCCGCTGAATTCGAGCGCCG
GATGGCCAACCAGCTGCCGGCCGACTGGGCCGAAAAGGCTGCGGCGATCATCGCCGGCGCGAACGAGCGCGGCGAGACGG
TGGCGACCCGCAAGGCGTCGCAGCAGGCGATCGAAGGCCTGGCTGCCGCGCTGCCCGAGCTGCTCGGCGGCTCGGCCGAC
CTGACCGGCTCGAACCTGACCAACTGGAAGGCGTCGAAGGCCGTCCGTGCGAATCCGGAAGGCCCGGGCGTCCAGCTGGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAACGGCCTCGCGCTGCATGGCGGCCACAAGC
CGTTCGGCGGCACGTTCCTGACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTGGCTGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGCCCGACGCACCAGTCGATCGAGCACGTGTCGAGCCT
GCGCCTGATCCCGAACCACGACGTGTGGCGCCCGGCCGACACGGTCGAGACGGCCGTCGCATGGACCCACGCGATCGCCG
CCGACCGTCCGTCGAGCCTGATCTTCAGCCGCCAGAACCTCGCGTTCAACCCGCGTACCGATGCGCAGATCGCGAACATC
GAGAAGGGCGGTTACGTGCTGAAGGACTGGGACGAAGAGATCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCGGA
AGTCGAACTCGCGATGAAGGCCATCGAGCCGCTCGCGCAGCAAGGTATCGCGGCACGTGTCGTGTCGATGCCGTCGACCA
ACGTGTTCGACCGCCAGGACGCCGAATACCGTGAACGCGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTGACCGCCTTCTGGCACAAGTACGTCGGCCTCGAAGGCGGCGTCGTCGGGATCGACACGTTCGGTGAATCGGCGCCGGC
CGGCGTGCTGTTCAAGTACTTCGGCTTCACCGTCGAGCACGTCGTCGAGACCGCCAAGGCCGTGCTGGCCTAA

Upstream 100 bases:

>100_bases
AAAATGACGAGCTTTGCAGCCCCGTCCGTAGGCTCCGTCCGCTTCGCGTCCGTCAGGCGCCGCACCGCGCGCCGGGAACG
ATCGACGCTCGAGCTTCCGG

Downstream 100 bases:

>100_bases
AGAGACATACGCGACGCGCGCCCCCCCCTCGCGCGCGTCGCACCGTGAAGCTGCACGAAACGAATTTTTTTCAGCCATCA
GGAGATAGACCATGACGATT

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPHVNGHD
VDAVDAAIAKAKLSDKPTLICCKTVIGQGAATKAGGHDVHGAALGAEEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGK
RAETEWDATFAAYRAKFPAEAAEFERRMANQLPADWAEKAAAIIAGANERGETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGPGVQLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAIAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAIEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTAFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Sequences:

>Translated_690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPHVNGHD
VDAVDAAIAKAKLSDKPTLICCKTVIGQGAATKAGGHDVHGAALGAEEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGK
RAETEWDATFAAYRAKFPAEAAEFERRMANQLPADWAEKAAAIIAGANERGETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGPGVQLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAIAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAIEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTAFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA
>Mature_689_residues
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDG
AKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPHVNGHDV
DAVDAAIAKAKLSDKPTLICCKTVIGQGAATKAGGHDVHGAALGAEEIAKTREALGWTWAPFVIPQEVYAAWDAKEAGKR
AETEWDATFAAYRAKFPAEAAEFERRMANQLPADWAEKAAAIIAGANERGETVATRKASQQAIEGLAAALPELLGGSADL
TGSNLTNWKASKAVRANPEGPGVQLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPSI
FVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAIAADRPSSLIFSRQNLAFNPRTDAQIANIE
KGGYVLKDWDEEIVARKIILIATGSEVELAMKAIEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGV
TAFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=606, Percent_Identity=28.0528052805281, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI4507521, Length=606, Percent_Identity=28.0528052805281, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI133778974, Length=589, Percent_Identity=26.3157894736842, Blast_Score=138, Evalue=2e-32,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=62.8912071535022, Blast_Score=863, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=60.3603603603604, Blast_Score=808, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=682, Percent_Identity=26.5395894428152, Blast_Score=164, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=673, Percent_Identity=49.777117384844, Blast_Score=610, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6319593, Length=679, Percent_Identity=46.0972017673049, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI45551847, Length=709, Percent_Identity=25.5289139633286, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550715, Length=709, Percent_Identity=25.5289139633286, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24666278, Length=674, Percent_Identity=24.9258160237389, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24645119, Length=660, Percent_Identity=25.3030303030303, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74210; Mature: 74078

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPMEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPHVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEEECCCCCCC
VDAVDAAIAKAKLSDKPTLICCKTVIGQGAATKAGGHDVHGAALGAEEIAKTREALGWTW
CHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRAETEWDATFAAYRAKFPAEAAEFERRMANQLPADWAEKA
CCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
AAIIAGANERGETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GPGVQLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCEECCCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAIAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAIEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTAFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPMEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPHVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEEECCCCCCC
VDAVDAAIAKAKLSDKPTLICCKTVIGQGAATKAGGHDVHGAALGAEEIAKTREALGWTW
CHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCC
APFVIPQEVYAAWDAKEAGKRAETEWDATFAAYRAKFPAEAAEFERRMANQLPADWAEKA
CCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
AAIIAGANERGETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GPGVQLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCCCEECCCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAIAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAIEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTAFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]