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The map label for this gene is aroC [H]

Identifier: 78048433

GI number: 78048433

Start: 3270497

End: 3271600

Strand: Reverse

Name: aroC [H]

Synonym: XCV2877

Alternate gene names: 78048433

Gene position: 3271600-3270497 (Counterclockwise)

Preceding gene: 78048434

Following gene: 78048432

Centisome position: 63.18

GC content: 67.03

Gene sequence:

>1104_bases
ATGAGTGCCAATTCGTTCGGCAAGCTGTTCACTGTCACCACCTTCGGCGAGTCGCACGGGCCGGCGATCGGTTGCGTCGT
CGACGGCTGCCCTCCCGGCCTGGAGCTCGCGCCGGAAGAGTTCACCCACGATCTGCAGCGCCGCGCTAGCGGCAAGAGCC
GGCACACCTCGGCGCGCCGCGAGGCCGACGAGATCGAGATCCTGTCCGGCGTGTACGAAGGCCGTACCACCGGCACGCCG
ATCGGCTTGCTGATCCGCAATACCGATCAGCGCAGCAAGGACTACAGCAACATCGCCCAGCAGTTCCGTCCCGGCCATGC
CGATTACACCTACTGGCAGAAGTACGGCATTCGCGATCCTCGCGGCGGCGGGCGTTCGTCGGCGCGCGAAACCACCATGC
GCGTGGCCGCCGGCGTGATCGCCAAGAAGTGGCTCAAGCAGCGCTATGGCGTGCTGGTGCGCGGTTTCCTGTCGCAGCTG
GGCCAGATCCGTCCCGCTGGTTTCGATTGGGATGCGGTGGAAGACAACCCGTTCTTCTGGCCGCATGCGGCGCAGGTGCC
GGAGCTGGAAACCTACATGGACGCGCTGCGCAAATCCGGCGACTCGGTCGGTGCGCGCGTGGACGTGGTGGCCGGCGGCG
TTCCGGCAGGCTGGGGCGAGCCGATCTACGGCAAGCTCGATGCCGAACTTGCGGCGGCGTTGATGAGCATCAATGCGGTC
AAGGGCGTGGAGATCGGCGACGGCTTCGCCAGCGCGGCGCAGAAGGGTACCGAACACCGCGACCTGATCACCCCGGAAGG
CTTTCTCAGCAACCATGCCGGCGGCATCCTGGGCGGTATTTCCACTGGCCAGGCGGTCACTGCTTCGATGGTGCTCAAGC
CCACTTCCAGCCTGCGCCTGCCCGGCGCGACGGTGGATGCCGATGGCAGCGTGGTCGATGTCATCACCACCGGCCGGCAC
GACCCGTGCGTGGGCATCCGCGCCACCCCGATCGCCGAGGCGATGATGGCGCTGGTGCTGATGGACCAGGCGTTGCGCCA
TCGTGCCCAGTGCGGCGATGTGGGCGAGGTGTCGCCGCGCATTCCCGGTCAGGTCGATGTCTGA

Upstream 100 bases:

>100_bases
AAGGTCGGGCAGATGGGCATCTTCGCCGTGGAATGCCGCGAATTGATCGCCCACGGTGCCCGCATCGCCGAGCTGGCCGC
GCAGCGATGAGCCTGCGCGC

Downstream 100 bases:

>100_bases
CGGACGTCGTCCCAGGGTGTGGGTGAGCCAGCCGCTGTTCGACGATGTCGTCGCGCAGCTGGGCGAGCATTTCGAGCTGA
CCACCACGCAGCGCGTCAGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLELAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GQIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV

Sequences:

>Translated_367_residues
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLELAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GQIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV
>Mature_366_residues
SANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLELAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTPI
GLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLG
QIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAVK
GVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRHD
PCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=63.3333333333333, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=41.2398921832884, Blast_Score=268, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39111; Mature: 38979

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLELAPEEFTHDLQRRASGKSRHTSARR
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGQIRPAGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPR
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQVDV
CCCCCCC
>Mature Secondary Structure 
SANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLELAPEEFTHDLQRRASGKSRHTSARR
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGQIRPAGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPR
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQVDV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]