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The map label for this gene is nuoC [H]

Identifier: 78048407

GI number: 78048407

Start: 3244976

End: 3245728

Strand: Reverse

Name: nuoC [H]

Synonym: XCV2851

Alternate gene names: 78048407

Gene position: 3245728-3244976 (Counterclockwise)

Preceding gene: 78048408

Following gene: 78048406

Centisome position: 62.68

GC content: 65.07

Gene sequence:

>753_bases
ATGGCAGAGCAAGCATCCTCCTTCACTGACCGACTTGCGGCACGTTTCGCCGGTGCGCAGATTGCCGTGGCATTGCCGCG
CGGCGAAGTGACGCTGGAAGTCGCGGCCGCCGATTGGCACGCCACCTGTCTTGCACTGCGTGACGAGCTCGGTTTCGAAC
AGCTCAGCGACCTGTGTGGCGTCGATTACCTGGGCTACGGCAGCGACGAGTGGGATACCGCCGACGTGTCGTCGCAGGGC
TTCAGTCGCGGCGTCGAAGGCAAGGCCGTCGGCCGTTTCGCCTGGGGCGAGTTCCCCAGCCAGGAAAGCTCTGCCGGCGC
GCAGCCGCAGCAGCTGCCCAAGCAACGTTTTGCGGTGGTCGCACAGCTGATTTCCTACCAGCACAACCAGCGTCTGCGCG
TGCGTTGCTACGCACCGGACGAGCAGGTGCCGGTGGTGGCGTCGTTGACCGATATCTGGCCGGGCGTGAACTGGTTCGAG
CGCGAGGCGTTTGACCTGTTCGGCATCGTGTTCGATGGGCACCCGGACCTGCGCCGCATCCTGACCGACTACGGATTCGT
CGGCCACCCGTTCCGCAAGGACTTTCCGCTGATCGGCAACGTCGAAGTGCGTTACGACGAGGAGCGCAAGCGCGTGGTGT
ACGAGCCGGTGACCTCGGTCGAGCCGCGCGTCGGCGTGCCGCGCGTCATTCGCGACGATGCCCGTTATGAGACTGCCGCT
GGTGAAGTGGGCAAGTCGGAGACTGCCAAGTGA

Upstream 100 bases:

>100_bases
GCTGGTCTACGGCATCTTGCAGCTGCAGAAGAAGATCTGGCGTACCCAGACGATCGCGCGCTGACACCCGTCTTCTTCTA
CCGAGAGCAGCCAAGCCCCC

Downstream 100 bases:

>100_bases
GTGAGTTCCGCCAGGCAACCGATGCCTTCGCGAGCAATCCTGTCGAAAGCAAGCAGGAAATCCGCAATTACACGATGAAC
TTCGGCCCGCAGCATCCTGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQG
FSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASLTDIWPGVNWFE
REAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
GEVGKSETAK

Sequences:

>Translated_250_residues
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQG
FSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASLTDIWPGVNWFE
REAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
GEVGKSETAK
>Mature_249_residues
AEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQGF
SRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASLTDIWPGVNWFER
EAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAAG
EVGKSETAK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=104, Percent_Identity=56.7307692307692, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI145693162, Length=87, Percent_Identity=47.1264367816092, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=59.2233009708738, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=59.2233009708738, Blast_Score=126, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24656494, Length=104, Percent_Identity=55.7692307692308, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 27817; Mature: 27686

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCG
CCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHC
VDYLGYGSDEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
AQLISYQHNQRLRVRCYAPDEQVPVVASLTDIWPGVNWFEREAFDLFGIVFDGHPDLRRI
HHHHHHCCCCEEEEEEECCCCCCCCEEEHHHHCCCCCHHHHHHHHEEEEEECCCHHHHHH
LTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
HHHCCCCCCCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHH
GEVGKSETAK
CCCCCCCCCC
>Mature Secondary Structure 
AEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCG
CCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHC
VDYLGYGSDEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
AQLISYQHNQRLRVRCYAPDEQVPVVASLTDIWPGVNWFEREAFDLFGIVFDGHPDLRRI
HHHHHHCCCCEEEEEEECCCCCCCCEEEHHHHCCCCCHHHHHHHHEEEEEECCCHHHHHH
LTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAA
HHHCCCCCCCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCHHHHHH
GEVGKSETAK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]