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The map label for this gene is aglA [H]

Identifier: 78048359

GI number: 78048359

Start: 3189436

End: 3191052

Strand: Reverse

Name: aglA [H]

Synonym: XCV2803

Alternate gene names: 78048359

Gene position: 3191052-3189436 (Counterclockwise)

Preceding gene: 78048360

Following gene: 78048355

Centisome position: 61.62

GC content: 61.78

Gene sequence:

>1617_bases
ATGTTGCAGACACCATGGTGGCGCGGGGCGGTCATCTACCAGATCTATCCGCGTAGTTTTCTGGATTCCAACGGCGATGG
TGTCGGCGATCTGCCGGGCATCATTGCCAAGCTCGACTACATCGCTGGGCTGGGTGTGGATGCCATCTGGATCTCGCCGT
TCTTCAAGTCGCCGATGGCCGATTTCGGCTATGACATCGCTGACTATCGTGCGGTGGATCCGTTGTTCGGGACGCTGGAC
GATTTCGACCGTCTGCTCGACAAGGCGCATGCGCTCGGGCTGAAGGTGATGATCGATCAGGTGTTGAGCCACACCTCGAT
CGAACATGCGTGGTTCCAGGAAAGCCGTCAGGATCGGACCAACGCGAAGGCGGATTGGTATGTATGGGCCGATCCGCGCG
AGGACGGGACGCCGCCGAACAACTGGTTGTCGCTATTCGGTGGTGTGGCGTGGCAGTGGGAGCCGCGGCGCGAGCAGTAC
TACCTGCATAACTTCCTGGTCGACCAGCCCGACCTCAATTTCCATAACGCCGAGGTGCAGCAGGCAACCCTGGACAATGT
GCGGTTCTGGTTGGACCGTGGAGTGGATGGCTTCCGCCTGGACGCGATCAACTTCTGCTTCCATGACGCGCAGCTGCGCG
ATAACCCCGCCAAGCCGGCCGACAAGCGGGTAGGGCGTGGCTTCAGTGCGGACAATCCGTATGCCTATCAATATCACTAC
TTCAACAACACGCAGCCGGAAAACCTGGCGTTCCTGGAGCGCCTGCGTGCGCTGCTCGATCGCTATCCGAATGCGGTAAG
CCTGGGCGAGATTTCGTCGGAAGATTCGTTGGCGACCACGGCCGAGTACACCGCCAAGGGCCGTCTGCACATGGGCTACA
GCTTCGAGCTGTTGGTGCAGGATTACAGTGCTGCCTATATCCGTGAAACGGTCAGCCGGCTCGAGGCGACCATGCTGGAA
GGCTGGCCGTGCTGGGCGATTTCCAATCACGACGTGGTGCGTGCGGTGACGCGTTGGGGCGGCGACGATGCGTCACCTGC
GTTCGCCCGCATGGTGGTGGCGCTGCTATGTTCGTTGCGTGGTTCGGTTTGCCTGTACCAGGGCGAGGAGCTTGGGCTGG
GCGAGGCGGATGTGGCATTCGAGGATCTGCAGGACCCCTATGGCATCACGTTCTGGCCGACTTTCAAGGGCCGCGATGGA
TGCCGTACGCCGATGCCGTGGACCGATGCGCCGTCGGCGGGTTTCACCAGCGGCAAGCCGTGGCTGCCGTTGTCCGAGCC
GCATCGTCTGGCTGCAGTGAGTGTGCAACAAGATGATGCCCAGTCTGTGCTGAGCGCCGTGCGGGCATTTCTGAGTTGGC
GCAAGAGCATGCCGGCCTTGCGGGAAGGGGCGATCGCGTTCTACGACACCGCAGAGCCGGTGCTGATGTTCCGGCGTGAG
CATGCCGGCCAGGTCATGCTGTTGGCGTTCAACTTGTCTGCCGACATCACCGAGCTGGCAGTGCCTGCAGGTGCATGGCG
CCAGATCGATGTGCCGGGGGTTGAGCGTGGGGTGATCGATCATGGTCGCTTGCGCTTGCCGGGGCACGCCGTCGTTTGTG
CAATGGGCGGGGAGTGA

Upstream 100 bases:

>100_bases
TACGTATGCACGTACGCGCCCGTGGTGCGCCACGCAGCTAGGCTAACGCCCTTAGTCGGCGGCCGTGTTGGCTGCCAGCA
GTGGCCCGGGAGGGGCGTGC

Downstream 100 bases:

>100_bases
CGCTACCGCTTCACAGAAAGCTTGATGGGTGTGTTTGATTGATACCGGCGAGGCGTTCCCTTGAGATGCCTCGCTTTTTT
GTGGTGGGTTGTTAGATCCG

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MLQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDKAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPNAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRETVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGDDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLQDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLSAVRAFLSWRKSMPALREGAIAFYDTAEPVLMFRRE
HAGQVMLLAFNLSADITELAVPAGAWRQIDVPGVERGVIDHGRLRLPGHAVVCAMGGE

Sequences:

>Translated_538_residues
MLQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDKAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPNAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRETVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGDDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLQDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLSAVRAFLSWRKSMPALREGAIAFYDTAEPVLMFRRE
HAGQVMLLAFNLSADITELAVPAGAWRQIDVPGVERGVIDHGRLRLPGHAVVCAMGGE
>Mature_538_residues
MLQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDKAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPNAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRETVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGDDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLQDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLSAVRAFLSWRKSMPALREGAIAFYDTAEPVLMFRRE
HAGQVMLLAFNLSADITELAVPAGAWRQIDVPGVERGVIDHGRLRLPGHAVVCAMGGE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=504, Percent_Identity=33.531746031746, Blast_Score=279, Evalue=4e-75,
Organism=Escherichia coli, GI1790687, Length=527, Percent_Identity=36.4326375711575, Blast_Score=305, Evalue=7e-84,
Organism=Escherichia coli, GI1786604, Length=497, Percent_Identity=23.7424547283702, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32565753, Length=380, Percent_Identity=27.3684210526316, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=440, Percent_Identity=25, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322245, Length=571, Percent_Identity=33.800350262697, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6319776, Length=556, Percent_Identity=35.2517985611511, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6321731, Length=556, Percent_Identity=35.2517985611511, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321726, Length=554, Percent_Identity=33.0324909747292, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322241, Length=556, Percent_Identity=32.9136690647482, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322021, Length=556, Percent_Identity=32.9136690647482, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6324416, Length=561, Percent_Identity=32.9768270944742, Blast_Score=266, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24586591, Length=520, Percent_Identity=36.7307692307692, Blast_Score=308, Evalue=7e-84,
Organism=Drosophila melanogaster, GI24583745, Length=520, Percent_Identity=37.5, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24583749, Length=515, Percent_Identity=37.2815533980583, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24583747, Length=515, Percent_Identity=37.2815533980583, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24586599, Length=520, Percent_Identity=35.7692307692308, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24586587, Length=498, Percent_Identity=35.9437751004016, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24586597, Length=507, Percent_Identity=36.6863905325444, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24586593, Length=503, Percent_Identity=36.779324055666, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI221330053, Length=531, Percent_Identity=34.0866290018832, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24586589, Length=520, Percent_Identity=35, Blast_Score=287, Evalue=2e-77,
Organism=Drosophila melanogaster, GI45549022, Length=514, Percent_Identity=32.4902723735409, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI281360393, Length=450, Percent_Identity=33.5555555555556, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 60445; Mature: 60445

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGTLDDFDRLLDKAHALGLKVMIDQVLSHTSIEHAWFQESRQDRT
HHCCCHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
NAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHEEHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEEHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRALLDRYPNAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCEEEECCEEEEEEH
DYSAAYIRETVSRLEATMLEGWPCWAISNHDVVRAVTRWGGDDASPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSVCLYQGEELGLGEADVAFEDLQDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLSEPHRLAAVSVQQDDAQSVLSAVRAFLSWRKSMPALREGAIAFYDTAEPVLMFRRE
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHH
HAGQVMLLAFNLSADITELAVPAGAWRQIDVPGVERGVIDHGRLRLPGHAVVCAMGGE
CCCEEEEEEEECCCCHHHHHCCCCCCEEECCCCCCCCCCCCCCEECCCCEEEEEECCC
>Mature Secondary Structure
MLQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGTLDDFDRLLDKAHALGLKVMIDQVLSHTSIEHAWFQESRQDRT
HHCCCHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
NAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHEEHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEEHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRALLDRYPNAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCEEEECCEEEEEEH
DYSAAYIRETVSRLEATMLEGWPCWAISNHDVVRAVTRWGGDDASPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSVCLYQGEELGLGEADVAFEDLQDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLSEPHRLAAVSVQQDDAQSVLSAVRAFLSWRKSMPALREGAIAFYDTAEPVLMFRRE
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHH
HAGQVMLLAFNLSADITELAVPAGAWRQIDVPGVERGVIDHGRLRLPGHAVVCAMGGE
CCCEEEEEEEECCCCHHHHHCCCCCCEEECCCCCCCCCCCCCCEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]