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The map label for this gene is fruR [H]

Identifier: 78048234

GI number: 78048234

Start: 3029935

End: 3031059

Strand: Reverse

Name: fruR [H]

Synonym: XCV2678

Alternate gene names: 78048234

Gene position: 3031059-3029935 (Counterclockwise)

Preceding gene: 78048239

Following gene: 78048230

Centisome position: 58.53

GC content: 66.76

Gene sequence:

>1125_bases
GTGGGAACGTTCCCACGATCCAGGTCAATGTGCGGTGCACAAAAACGCTGTAGTGCTTTCGGGTTAGCATCAAGACCGGC
ACCGCGCCTGGGTCAGGGTGCGCAAAATGGAGCGGGAACGGTCCCAGTGAGTATCAGCATCAATGACGTGGCCCGCGTGG
CCGGAGTGTCCAAGTCCACGGTGTCGCGCGCGCTGGGCAGCGGCCCGGTCAGCGAGGAAGTGCGTGCCAAGGTGGAAGCG
GCGGTGCGCCAGACCGGCTATCGGCCCAACCTGATGGCGCGGCGATTGCGATCCCAGCAATCCGGCATCCTGGGGGTGAT
CGTGGCCGACATCCGCAACCCGTACTTCACGGCGCTGATCCGTGCGGTGGAAGAGGTCGCCTACAGGGCCGGTATGCGCG
TGACGCTGTGCAATACCGATGAAGATCCCGAGCGAGAGGCGCTATACCTGGAGTTGATGCAGGAAGAACGCATCACCGGG
CTGATTTTTGCGCCGACCCGGGTCACGGTGGGGCGCATGCACGAGCTGGCGCTGGATTACCCCACCGTGCTGGTGGATCG
CGCCGGCCCCGGCAGCCGCTACGACAGTGTGGTGCTGGATAACGGCGCGGCCATGGCCGAGCTGGTGGCGCATCTGCAGG
CGCAGGGCTACCGGCGCATCGGCGGGCTGTTCGGCAGCACCAGCACCACGGCGGCCGAGCGCCGCGATGGTTACCTGGCC
GCGATGCGCGCGCAGGGGCTGCAGCCGGATTACCGCGAAGTGGCGCCCACCGCCGAGGCGGCGATTGCCGAGTTGGGTGC
ATGGCTGGCCAACGACCAGCGGCCCGAGGCCATCGTGACCAGTAACAGCCTGCTGCTGATGGGCGCACTGAAGGCTGCAC
GCACCGCCGGCCTGCGCCTGCCGCAGGATCTGGCCCTGGCCGGGTTCGACAACGAGCGCTGGACCGATCTGGTCGAGCCG
GGTATCACTGTGGTCGAGCAGCCGGTGGAAGACATGGGCCGGGCGGCGATGTCGCTGCTGCTGGAACGGTTAAGCAATCG
GCAATTGCCGATCCGCCGCTTGGTCATGACTGGACGTTGCGTGGTGCGTGGGTCGACTGCTGCGCGTATGCCGGGCGTGG
TGTAG

Upstream 100 bases:

>100_bases
TCGCGGGCAGAGGCGCGCAGGCACACAAGGTCGGGGGTGACGGGGGCGGGCGACGGAGAGGACAAGGCGGGCTCCGGATG
AGGTCGGGCTGGGAAGTATA

Downstream 100 bases:

>100_bases
AGCGGCGGCGAGGGTCTGTTGGGTGCGGTGGGTTTGACGGGAATGCGTTCGCGCCCGAGTGCGCTCCTACAAAGAGGGCC
GTCTGCCGTGGATTGCGGAC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MGTFPRSRSMCGAQKRCSAFGLASRPAPRLGQGAQNGAGTVPVSISINDVARVAGVSKSTVSRALGSGPVSEEVRAKVEA
AVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRAVEEVAYRAGMRVTLCNTDEDPEREALYLELMQEERITG
LIFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLA
AMRAQGLQPDYREVAPTAEAAIAELGAWLANDQRPEAIVTSNSLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEP
GITVVEQPVEDMGRAAMSLLLERLSNRQLPIRRLVMTGRCVVRGSTAARMPGVV

Sequences:

>Translated_374_residues
MGTFPRSRSMCGAQKRCSAFGLASRPAPRLGQGAQNGAGTVPVSISINDVARVAGVSKSTVSRALGSGPVSEEVRAKVEA
AVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRAVEEVAYRAGMRVTLCNTDEDPEREALYLELMQEERITG
LIFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLA
AMRAQGLQPDYREVAPTAEAAIAELGAWLANDQRPEAIVTSNSLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEP
GITVVEQPVEDMGRAAMSLLLERLSNRQLPIRRLVMTGRCVVRGSTAARMPGVV
>Mature_373_residues
GTFPRSRSMCGAQKRCSAFGLASRPAPRLGQGAQNGAGTVPVSISINDVARVAGVSKSTVSRALGSGPVSEEVRAKVEAA
VRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRAVEEVAYRAGMRVTLCNTDEDPEREALYLELMQEERITGL
IFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAA
MRAQGLQPDYREVAPTAEAAIAELGAWLANDQRPEAIVTSNSLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPG
ITVVEQPVEDMGRAAMSLLLERLSNRQLPIRRLVMTGRCVVRGSTAARMPGVV

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=32.8313253012048, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=31.9148936170213, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=33.6538461538462, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787948, Length=337, Percent_Identity=29.673590504451, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789202, Length=316, Percent_Identity=32.2784810126582, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=30.03003003003, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789068, Length=295, Percent_Identity=29.8305084745763, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787580, Length=330, Percent_Identity=28.7878787878788, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=30.2631578947368, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786268, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=27.8846153846154, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=27.8846153846154, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789456, Length=335, Percent_Identity=24.4776119402985, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786540, Length=306, Percent_Identity=26.4705882352941, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 40231; Mature: 40100

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTFPRSRSMCGAQKRCSAFGLASRPAPRLGQGAQNGAGTVPVSISINDVARVAGVSKST
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCHHH
VSRALGSGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALI
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEHHCCHHHHHHH
RAVEEVAYRAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELALDY
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCC
PTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLA
CEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCCHHH
AMRAQGLQPDYREVAPTAEAAIAELGAWLANDQRPEAIVTSNSLLLMGALKAARTAGLRL
HHHHCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
PQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLSNRQLPIRRLVMTGRC
CHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCE
VVRGSTAARMPGVV
EEECCCCCCCCCCC
>Mature Secondary Structure 
GTFPRSRSMCGAQKRCSAFGLASRPAPRLGQGAQNGAGTVPVSISINDVARVAGVSKST
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCHHH
VSRALGSGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALI
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEHHCCHHHHHHH
RAVEEVAYRAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELALDY
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCC
PTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLA
CEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCCHHH
AMRAQGLQPDYREVAPTAEAAIAELGAWLANDQRPEAIVTSNSLLLMGALKAARTAGLRL
HHHHCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
PQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLSNRQLPIRRLVMTGRC
CHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCE
VVRGSTAARMPGVV
EEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]