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The map label for this gene is dapA1 [H]

Identifier: 78044485

GI number: 78044485

Start: 1028375

End: 1029256

Strand: Direct

Name: dapA1 [H]

Synonym: CHY_1156

Alternate gene names: 78044485

Gene position: 1028375-1029256 (Clockwise)

Preceding gene: 78044009

Following gene: 78043054

Centisome position: 42.82

GC content: 44.22

Gene sequence:

>882_bases
ATGGCAGTGTTTGGACGATTGTTAACCGCTATGGTAACCCCTTTTGATCGGGATGGGAAGGTTAACCTGGAGCAGGCACA
AAAATTAGCCAGTTTCTTGGTGGAAAACGGTTCTGATGGTATTGTGGTGGCGGGGACTACCGGTGAATCACCAACTTTAT
CCTTTGAAGAAAAAGTAGACCTTTTTAAAGCTGTTGTCGAAGCGGTAGGTGGAAAAGCAGCAGTTATTGCCGGAACGGGA
TCCAATGCAACGGAAGCTTCGATTAAACTTACTAAAGCTGCGGAAAAGGTCGGAGTAGATGGGGTTATGCTGGTAGCTCC
GTACTATAACAAACCTTCCCAAAAGGGGCTTGTCGAACATTTTCAGGCGATTGCCAGAGCCACCAGCTTACCGGTTATGA
TTTATAACATTCCCGGTCGCACAGGGGTTAATATCTTACCCAAGACGATGGCTAAAATTGCCGAACTGGAAAATGTTGTA
GCAATTAAAGAAGCTGCGGGAAGTGTTGATCAGGCAACCGAACTAATAAGAATTTTACCGGAAAGGGTAAAGGTATTTTC
CGGAGATGACAGCTTGACCCTGCCCATTTTAGCGGTGGGAGGTTACGGAGTTGTTAGTGTGGCAAGTCACCTTGTTGGTC
TAAAAATAAAAGAAATGATCGATCAGTTTCTTTTAGGAAATGTGGCGGTGGCAGCTCGCCTCCACCAGGAGCTTTATCCT
TTAATTAAAGCATTATTTATAACAACTAATCCGGTACCAGTAAAAACTGCGCTGAATTTAATGGGACATAAAGTTGGTGG
TTTTAGACTTCCGCTGGTGGATATGACCGAGGAGGAAAAGGAGGAACTGGTACGGGAATTGAAAAACCTTAATTTGTTGT
AA

Upstream 100 bases:

>100_bases
ATCTGGGTACTGGTGGATGGGGAAAATATGGAAAAAGCTGTTAGGGCTATTCACAAAGCTTTTAAACTAAACGAATAAAA
AATTAAAAGAAGGTGAAAAG

Downstream 100 bases:

>100_bases
ATTAAAAAATCTTTGGGGAAGGCTATTTTCACTTGTCCTTCCTTTTTTTATTTTTTATAATTACAATAGATTGTAAAAAG
CTAACAAATGGGCGGTTTAA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAVFGRLLTAMVTPFDRDGKVNLEQAQKLASFLVENGSDGIVVAGTTGESPTLSFEEKVDLFKAVVEAVGGKAAVIAGTG
SNATEASIKLTKAAEKVGVDGVMLVAPYYNKPSQKGLVEHFQAIARATSLPVMIYNIPGRTGVNILPKTMAKIAELENVV
AIKEAAGSVDQATELIRILPERVKVFSGDDSLTLPILAVGGYGVVSVASHLVGLKIKEMIDQFLLGNVAVAARLHQELYP
LIKALFITTNPVPVKTALNLMGHKVGGFRLPLVDMTEEEKEELVRELKNLNLL

Sequences:

>Translated_293_residues
MAVFGRLLTAMVTPFDRDGKVNLEQAQKLASFLVENGSDGIVVAGTTGESPTLSFEEKVDLFKAVVEAVGGKAAVIAGTG
SNATEASIKLTKAAEKVGVDGVMLVAPYYNKPSQKGLVEHFQAIARATSLPVMIYNIPGRTGVNILPKTMAKIAELENVV
AIKEAAGSVDQATELIRILPERVKVFSGDDSLTLPILAVGGYGVVSVASHLVGLKIKEMIDQFLLGNVAVAARLHQELYP
LIKALFITTNPVPVKTALNLMGHKVGGFRLPLVDMTEEEKEELVRELKNLNLL
>Mature_292_residues
AVFGRLLTAMVTPFDRDGKVNLEQAQKLASFLVENGSDGIVVAGTTGESPTLSFEEKVDLFKAVVEAVGGKAAVIAGTGS
NATEASIKLTKAAEKVGVDGVMLVAPYYNKPSQKGLVEHFQAIARATSLPVMIYNIPGRTGVNILPKTMAKIAELENVVA
IKEAAGSVDQATELIRILPERVKVFSGDDSLTLPILAVGGYGVVSVASHLVGLKIKEMIDQFLLGNVAVAARLHQELYPL
IKALFITTNPVPVKTALNLMGHKVGGFRLPLVDMTEEEKEELVRELKNLNLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=23.7931034482759, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI13540533, Length=304, Percent_Identity=26.6447368421053, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=37.6712328767123, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI87082415, Length=293, Percent_Identity=29.3515358361775, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786463, Length=285, Percent_Identity=28.0701754385965, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789620, Length=256, Percent_Identity=28.515625, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31243; Mature: 31112

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFGRLLTAMVTPFDRDGKVNLEQAQKLASFLVENGSDGIVVAGTTGESPTLSFEEKVD
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
LFKAVVEAVGGKAAVIAGTGSNATEASIKLTKAAEKVGVDGVMLVAPYYNKPSQKGLVEH
HHHHHHHHCCCCEEEEEECCCCCCHHHEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
FQAIARATSLPVMIYNIPGRTGVNILPKTMAKIAELENVVAIKEAAGSVDQATELIRILP
HHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ERVKVFSGDDSLTLPILAVGGYGVVSVASHLVGLKIKEMIDQFLLGNVAVAARLHQELYP
HHHHEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIKALFITTNPVPVKTALNLMGHKVGGFRLPLVDMTEEEKEELVRELKNLNLL
HHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVFGRLLTAMVTPFDRDGKVNLEQAQKLASFLVENGSDGIVVAGTTGESPTLSFEEKVD
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
LFKAVVEAVGGKAAVIAGTGSNATEASIKLTKAAEKVGVDGVMLVAPYYNKPSQKGLVEH
HHHHHHHHCCCCEEEEEECCCCCCHHHEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
FQAIARATSLPVMIYNIPGRTGVNILPKTMAKIAELENVVAIKEAAGSVDQATELIRILP
HHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ERVKVFSGDDSLTLPILAVGGYGVVSVASHLVGLKIKEMIDQFLLGNVAVAARLHQELYP
HHHHEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIKALFITTNPVPVKTALNLMGHKVGGFRLPLVDMTEEEKEELVRELKNLNLL
HHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA