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The map label for this gene is cheB1

Identifier: 78043438

GI number: 78043438

Start: 858495

End: 859517

Strand: Direct

Name: cheB1

Synonym: CHY_0968

Alternate gene names: 78043438

Gene position: 858495-859517 (Clockwise)

Preceding gene: 78042810

Following gene: 78044082

Centisome position: 35.75

GC content: 46.82

Gene sequence:

>1023_bases
ATGTCGCGGTATAAACTTTTTATTGTGGATGATTCGGCCTTAATCCGTCTCCGGCTGAAGACAAGTCTGGCTTTATGGCC
CGAAATCCAGATAGTTGGGGAAGCGGAAAATGGTCAGGAAGCTTTAAAGAAAATCCCATTAGTTAAGCCCGATGTAGTTA
CGCTGGATTTAGAAATGCCGGTACTGGATGGTCTTAGTACCTTAAAAGAGTTAAACAAAGTTTATCCGGTACCGGTAATC
ATGCTTTCTTCTTTAACAACCCACGGAGCTAAGGCAACTATTGAGGCCCTGGAAAATGGTGCGGTAGATTTTGTACCAAA
AGATGGGGATTGGAATAAGGTTGTTTCTGAGTTAAAAGAAAAGATAAAAATAGCTGTCTTAGCTAAAAAACGTCCGAAAC
CTTTTACCGGAGGGACGCTTAACCCCAAAAATGTTATTCTCGGTAAAAACGGCCGGCAATTGGTGGTGATAGGTGCTTCT
ACCGGTGGACCGCCGGCCTTACGAGAAATCATTCCCAAACTTCCGCAAACCTTTCCGGTGCCCATTGTAATTATCCAGCA
TATTACCCGCGGGTTTAGCAAGCCGCTGGCGGACCAGCTGGCCAGAGTTTCCCGGTTAAAGGTAAAGGAAGCGGAAAAAG
ACGAGCAGTTGCTCCCGGGAACGGTCTATGTGGCCCCTGCCGGCTATACTTTTAAAATTGATAAACAAGGAGGCAGTTTA
ACAGCTAAAATAATTGAGCCGGTGGAATACTTGCCGGCTCATTTCTACCCCTCCGTTGATGAGGCGATGCTTTCGGCAGC
AGAAGTGACGGGCAGCAAAACCATAGGAGTTTTGCTAACTGGCATGGGAAAGGATGGGGCGCTCGGGATGAAAGCTATCA
AAGAACGGGGAGGGTATACCATTGCCCAGGACGAAGAAACTTCGGTAGTTTACGGTATGCCCAAAGCGGCAATTGATATA
GGGGGAGTTTCTCGGGTTTTGCCCCTATCGGCAATTGCTGAAGAAATTGCGGCCAATATCTAA

Upstream 100 bases:

>100_bases
GTCAAGGGTCTATCGGGAGCTACAATCCTTGGCGATGGCCGGATCGGTCTTATCATTGATGCCCGCGGGATTTTGCAGGA
GAATGAAATAGGTGAATTAA

Downstream 100 bases:

>100_bases
AGAAATTAAATTTTTTTCCGAAGTATTAGATAGCACCAAAATGATACGAGGGGATAGTATGAGGATAAACGGGGTAGATT
TTAAGAATGTAGTGGAGCTT

Product: protein-glutamate methylesterase CheB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMPVLDGLSTLKELNKVYPVPVI
MLSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKEKIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGAS
TGGPPALREIIPKLPQTFPVPIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSL
TAKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYTIAQDEETSVVYGMPKAAIDI
GGVSRVLPLSAIAEEIAANI

Sequences:

>Translated_340_residues
MSRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMPVLDGLSTLKELNKVYPVPVI
MLSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKEKIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGAS
TGGPPALREIIPKLPQTFPVPIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSL
TAKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYTIAQDEETSVVYGMPKAAIDI
GGVSRVLPLSAIAEEIAANI
>Mature_339_residues
SRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMPVLDGLSTLKELNKVYPVPVIM
LSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKEKIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGAST
GGPPALREIIPKLPQTFPVPIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSLT
AKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYTIAQDEETSVVYGMPKAAIDIG
GVSRVLPLSAIAEEIAANI

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=350, Percent_Identity=38.2857142857143, Blast_Score=225, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB1_CARHZ (Q3ADG9)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359815.1
- ProteinModelPortal:   Q3ADG9
- SMR:   Q3ADG9
- STRING:   Q3ADG9
- GeneID:   3728901
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0968
- NMPDR:   fig|246194.3.peg.445
- TIGR:   CHY_0968
- eggNOG:   COG2201
- HOGENOM:   HBG705324
- OMA:   GGYHMEV
- BioCyc:   CHYD246194:CHY_0968-MONOMER
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 36528; Mature: 36397

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 160-160 ACT_SITE 187-187 ACT_SITE 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMP
CCCEEEEEECCCEEEEEEEECCEEECCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCC
VLDGLSTLKELNKVYPVPVIMLSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKE
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
KIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGASTGGPPALREIIPKLPQTFPV
HHEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCH
PIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCCE
TAKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYT
EHHHHHHHHHCCHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCEE
IAQDEETSVVYGMPKAAIDIGGVSRVLPLSAIAEEIAANI
EECCCCCEEEEECCHHHEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMP
CCEEEEEECCCEEEEEEEECCEEECCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCC
VLDGLSTLKELNKVYPVPVIMLSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKE
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
KIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGASTGGPPALREIIPKLPQTFPV
HHEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCH
PIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCCE
TAKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYT
EHHHHHHHHHCCHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCEE
IAQDEETSVVYGMPKAAIDIGGVSRVLPLSAIAEEIAANI
EECCCCCEEEEECCHHHEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA