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The map label for this gene is fepG [H]

Identifier: 77465416

GI number: 77465416

Start: 480267

End: 481307

Strand: Reverse

Name: fepG [H]

Synonym: RSP_3414

Alternate gene names: 77465416

Gene position: 481307-480267 (Counterclockwise)

Preceding gene: 77465417

Following gene: 77465415

Centisome position: 51.04

GC content: 73.29

Gene sequence:

>1041_bases
GTGACCCCCGCACCTTCCCTTGCCGCCGAGGTCGCGGCCCACCGTCGCCGTCGCCTGCGCCGGGGCGCAGCCCTCGTGCT
CGGCCTCGTCCTCCTGATCCTCGCATCCGTGGCGGTGACGCTCTCGGTCGGCTCGACGCCCGTGGCGCCGTTCGACGTGC
TCCGCGTGCTGGCCGGGCAGGAGGTGCCGGGGGCCTCCTTCACCGTCGAGCGGCTGCGGCTGCCGCGCGCGGTGCTGTCC
CTTCTGGCCGGCCTCTGCTTCGGCTTGGGCGGCGCCGCCTGCCAGACCCTGCTCCGCAGCCCGCTGGCCAGCCCCGACAT
CATCGGCATCTCGGCAGGCAGCGGGGCCGCCGCCGTCTTCGCTATTGTGGTCCTGGGCTGGAGCGGGCCTGCCGTCTCGG
GCGCAGCCATCCTCTGCGGGCTCGCCACCGCGCTTGCGATCTATCTCCTGGCCTGGCGGGACGGGGTGGCGGGCGCGCGG
CTGATCCTCGTGGGGATCGGGATCTCGGCCATGCTGCAGAGCGTGACCGCCTATCTCCTCCTGCGCGCCCCGGACTGGAG
CCTGCAGGAGGCGCTGCGCTGGATGACAGGCAGCGTGAACGGCGCCCGGCTGTCGGACGCACCGCCCCTCCTGCTGGCGC
TCGCCCTGTTCGGAACCCTCCTCCTGTGCCGGAGCCGCGAGCTCGAGGCCCTGCGGCTCGGCGACGACAAGGCGGCGGCG
CTCGGCGTGCGGATCGCGCGGACGCGGCTTCTGATCCTCGTGGGCGTGGTCGGGCTGATCGCGGTGGCGACCGCCGTCGC
GGGCCCCATCGCCTTCGTGGCCTTCCTCGCAGGCCCCATCGCCGCGCGTCTGGGCATGCCGGGTCGGCCGATCCTGCTGC
CGGCCGCGCTGATCGGCGCGCTTCTCGTTCTTCTGGCCGATTTCGCAGGGCAGGTGCTTCTGCCCGGCCGCTATCCGGTC
GGAATCGTCACTGGCGCCCTCGGCGCGCCTTACCTCATCTATCTCATCGTCCGGGTGAACCGGGCCGGAGGCACCATATG
A

Upstream 100 bases:

>100_bases
TCCTCGCCCGTCCGGGAGAGCTCGACGTGGGCATCGTCACGGCCTTCGTGGGTGCACCGGTCTTCATCTGGATCGTGCGG
CAACGAAGGATCCGCGAGCT

Downstream 100 bases:

>100_bases
CCGACAATGCGCTGGTGGTCAGCGAGCTTGCCGCTGGCTACGGCGACCGGCAAGTGCTGCGCGGGCTCGATCTCGCGGTG
GCGCCCGGCCGGATCACCGC

Product: ABC Fe+3-siderophore transporter, inner membrane subunit

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTPAPSLAAEVAAHRRRRLRRGAALVLGLVLLILASVAVTLSVGSTPVAPFDVLRVLAGQEVPGASFTVERLRLPRAVLS
LLAGLCFGLGGAACQTLLRSPLASPDIIGISAGSGAAAVFAIVVLGWSGPAVSGAAILCGLATALAIYLLAWRDGVAGAR
LILVGIGISAMLQSVTAYLLLRAPDWSLQEALRWMTGSVNGARLSDAPPLLLALALFGTLLLCRSRELEALRLGDDKAAA
LGVRIARTRLLILVGVVGLIAVATAVAGPIAFVAFLAGPIAARLGMPGRPILLPAALIGALLVLLADFAGQVLLPGRYPV
GIVTGALGAPYLIYLIVRVNRAGGTI

Sequences:

>Translated_346_residues
MTPAPSLAAEVAAHRRRRLRRGAALVLGLVLLILASVAVTLSVGSTPVAPFDVLRVLAGQEVPGASFTVERLRLPRAVLS
LLAGLCFGLGGAACQTLLRSPLASPDIIGISAGSGAAAVFAIVVLGWSGPAVSGAAILCGLATALAIYLLAWRDGVAGAR
LILVGIGISAMLQSVTAYLLLRAPDWSLQEALRWMTGSVNGARLSDAPPLLLALALFGTLLLCRSRELEALRLGDDKAAA
LGVRIARTRLLILVGVVGLIAVATAVAGPIAFVAFLAGPIAARLGMPGRPILLPAALIGALLVLLADFAGQVLLPGRYPV
GIVTGALGAPYLIYLIVRVNRAGGTI
>Mature_345_residues
TPAPSLAAEVAAHRRRRLRRGAALVLGLVLLILASVAVTLSVGSTPVAPFDVLRVLAGQEVPGASFTVERLRLPRAVLSL
LAGLCFGLGGAACQTLLRSPLASPDIIGISAGSGAAAVFAIVVLGWSGPAVSGAAILCGLATALAIYLLAWRDGVAGARL
ILVGIGISAMLQSVTAYLLLRAPDWSLQEALRWMTGSVNGARLSDAPPLLLALALFGTLLLCRSRELEALRLGDDKAAAL
GVRIARTRLLILVGVVGLIAVATAVAGPIAFVAFLAGPIAARLGMPGRPILLPAALIGALLVLLADFAGQVLLPGRYPVG
IVTGALGAPYLIYLIVRVNRAGGTI

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=308, Percent_Identity=40.9090909090909, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1786805, Length=297, Percent_Identity=36.026936026936, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790740, Length=335, Percent_Identity=32.8358208955224, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=33.9285714285714, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790741, Length=307, Percent_Identity=32.8990228013029, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788004, Length=299, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35242; Mature: 35111

Theoretical pI: Translated: 11.64; Mature: 11.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAPSLAAEVAAHRRRRLRRGAALVLGLVLLILASVAVTLSVGSTPVAPFDVLRVLAGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
EVPGASFTVERLRLPRAVLSLLAGLCFGLGGAACQTLLRSPLASPDIIGISAGSGAAAVF
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
AIVVLGWSGPAVSGAAILCGLATALAIYLLAWRDGVAGARLILVGIGISAMLQSVTAYLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHH
LRAPDWSLQEALRWMTGSVNGARLSDAPPLLLALALFGTLLLCRSRELEALRLGDDKAAA
HCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHH
LGVRIARTRLLILVGVVGLIAVATAVAGPIAFVAFLAGPIAARLGMPGRPILLPAALIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LLVLLADFAGQVLLPGRYPVGIVTGALGAPYLIYLIVRVNRAGGTI
HHHHHHHHCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPAPSLAAEVAAHRRRRLRRGAALVLGLVLLILASVAVTLSVGSTPVAPFDVLRVLAGQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
EVPGASFTVERLRLPRAVLSLLAGLCFGLGGAACQTLLRSPLASPDIIGISAGSGAAAVF
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
AIVVLGWSGPAVSGAAILCGLATALAIYLLAWRDGVAGARLILVGIGISAMLQSVTAYLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHH
LRAPDWSLQEALRWMTGSVNGARLSDAPPLLLALALFGTLLLCRSRELEALRLGDDKAAA
HCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHH
LGVRIARTRLLILVGVVGLIAVATAVAGPIAFVAFLAGPIAARLGMPGRPILLPAALIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LLVLLADFAGQVLLPGRYPVGIVTGALGAPYLIYLIVRVNRAGGTI
HHHHHHHHCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]