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The map label for this gene is dapA [H]

Identifier: 77465410

GI number: 77465410

Start: 474142

End: 475026

Strand: Reverse

Name: dapA [H]

Synonym: RSP_3408

Alternate gene names: 77465410

Gene position: 475026-474142 (Counterclockwise)

Preceding gene: 77465411

Following gene: 77465409

Centisome position: 50.37

GC content: 68.14

Gene sequence:

>885_bases
ATGACGCGCAACGCCCATGTCGCCCTCGTGACCTGCTTTCACGAGGACGAGACCGTCAACTATGCAGCCACCCGCGCCCA
GGTGCGCCGCCAGCTGGCCGCCGGCAACGATCTCATGGTCTGCGGCACGAACGGCGATTTCTCGGCTCTGACCCATGACG
AGAAGATCCGTCTGGTGGGAGAGGTGATGGAGGAAGTGGCGGGCCGCGCGAAGGTCATCGCCAACGTCGGCTGCCCCGCC
ACCTTCGAGACGCTCCAGCTCGCCCGCGCGGTGGATGGGATGGGCCTGCACGGCATCGCGGTCATTGCGCCCTACTTCAT
CTCCTGCACGCAGGACGGGCTGATCCGGCACTTCTCGACCGTCGCCGATGCCGTGACGACGCCGGTCTATCTCTACGACA
TCCCGGCCCGCACCCAGAACCATATCGAGCCTGCCACGGTGGGCACGCTCGCCCGTCATGGCAACATCGCGGGGATCAAG
GATTCCGGCGGCTCGACCGACACGGTGCGCGCCTATCTCGACGTGGCGCGCGATGTGGAGGGGTTCGAAGTCTACTGCGC
GCCCGACCATCTGGTGCTCTGGGGCCTCGAGGAAGGCTGCGCGGGCGTCGTCTCGGGGCTCGGCAACGTGGCTCCGGGCC
TGCTGGCGCAGATCATCGCGGGCTTCAACGCGGGCGACATGGAGGCCGCGCGCGCGGCGCAGGAAAACTTTGCGGGCCTG
CGGAAGGACCTCTATGCCCTGGGCTTCCCGCCGGCGCTCGTCAAGCGCGCGCTCTATCTGAACGATCCTTCGGTCGGCCT
CTCCCGGCAGCCCGCGCTGCTGCCAGACGCCGCGCAGGACGCGCAGATCCTCGCCATCCTCACCGCGCGGGGCCTGAAGG
AATGA

Upstream 100 bases:

>100_bases
GCTTTTCCTCGGGCTGTCGCTCCTGTCGCTTCTCTGGCCGTGGATCGCCGCGCGCCGTGCGGCGGGCAAGCCCTCCTCCC
CCCACCAGAACGGATAGAAG

Downstream 100 bases:

>100_bases
CCGTCGTCCTGACCACCTCGCCGGGCTTCGGCCGCCACGGACGGGTGCCCGCCCGGATCGAGGCCGAGGGCTGGACCTTC
CTGCGTGCCGCCGACGCGGC

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTRNAHVALVTCFHEDETVNYAATRAQVRRQLAAGNDLMVCGTNGDFSALTHDEKIRLVGEVMEEVAGRAKVIANVGCPA
TFETLQLARAVDGMGLHGIAVIAPYFISCTQDGLIRHFSTVADAVTTPVYLYDIPARTQNHIEPATVGTLARHGNIAGIK
DSGGSTDTVRAYLDVARDVEGFEVYCAPDHLVLWGLEEGCAGVVSGLGNVAPGLLAQIIAGFNAGDMEAARAAQENFAGL
RKDLYALGFPPALVKRALYLNDPSVGLSRQPALLPDAAQDAQILAILTARGLKE

Sequences:

>Translated_294_residues
MTRNAHVALVTCFHEDETVNYAATRAQVRRQLAAGNDLMVCGTNGDFSALTHDEKIRLVGEVMEEVAGRAKVIANVGCPA
TFETLQLARAVDGMGLHGIAVIAPYFISCTQDGLIRHFSTVADAVTTPVYLYDIPARTQNHIEPATVGTLARHGNIAGIK
DSGGSTDTVRAYLDVARDVEGFEVYCAPDHLVLWGLEEGCAGVVSGLGNVAPGLLAQIIAGFNAGDMEAARAAQENFAGL
RKDLYALGFPPALVKRALYLNDPSVGLSRQPALLPDAAQDAQILAILTARGLKE
>Mature_293_residues
TRNAHVALVTCFHEDETVNYAATRAQVRRQLAAGNDLMVCGTNGDFSALTHDEKIRLVGEVMEEVAGRAKVIANVGCPAT
FETLQLARAVDGMGLHGIAVIAPYFISCTQDGLIRHFSTVADAVTTPVYLYDIPARTQNHIEPATVGTLARHGNIAGIKD
SGGSTDTVRAYLDVARDVEGFEVYCAPDHLVLWGLEEGCAGVVSGLGNVAPGLLAQIIAGFNAGDMEAARAAQENFAGLR
KDLYALGFPPALVKRALYLNDPSVGLSRQPALLPDAAQDAQILAILTARGLKE

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=202, Percent_Identity=28.7128712871287, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI87082415, Length=291, Percent_Identity=30.9278350515464, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786463, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788823, Length=240, Percent_Identity=31.25, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789620, Length=271, Percent_Identity=23.9852398523985, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31139; Mature: 31008

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNAHVALVTCFHEDETVNYAATRAQVRRQLAAGNDLMVCGTNGDFSALTHDEKIRLVG
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHH
EVMEEVAGRAKVIANVGCPATFETLQLARAVDGMGLHGIAVIAPYFISCTQDGLIRHFST
HHHHHHCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
VADAVTTPVYLYDIPARTQNHIEPATVGTLARHGNIAGIKDSGGSTDTVRAYLDVARDVE
HHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCC
GFEVYCAPDHLVLWGLEEGCAGVVSGLGNVAPGLLAQIIAGFNAGDMEAARAAQENFAGL
CCEEEECCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKDLYALGFPPALVKRALYLNDPSVGLSRQPALLPDAAQDAQILAILTARGLKE
HHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCC
>Mature Secondary Structure 
TRNAHVALVTCFHEDETVNYAATRAQVRRQLAAGNDLMVCGTNGDFSALTHDEKIRLVG
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHH
EVMEEVAGRAKVIANVGCPATFETLQLARAVDGMGLHGIAVIAPYFISCTQDGLIRHFST
HHHHHHCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
VADAVTTPVYLYDIPARTQNHIEPATVGTLARHGNIAGIKDSGGSTDTVRAYLDVARDVE
HHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCC
GFEVYCAPDHLVLWGLEEGCAGVVSGLGNVAPGLLAQIIAGFNAGDMEAARAAQENFAGL
CCEEEECCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKDLYALGFPPALVKRALYLNDPSVGLSRQPALLPDAAQDAQILAILTARGLKE
HHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA