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The map label for this gene is pdxA [H]

Identifier: 77465408

GI number: 77465408

Start: 472183

End: 473169

Strand: Reverse

Name: pdxA [H]

Synonym: RSP_3406

Alternate gene names: 77465408

Gene position: 473169-472183 (Counterclockwise)

Preceding gene: 77465409

Following gene: 77465405

Centisome position: 50.18

GC content: 70.52

Gene sequence:

>987_bases
ATGTCCAGTTCCCCCCAACCCATCGTCATCACGATGGGCGATCCGTCCGGGGTCGGCGCCGAAGTGACGGTGAAGGCGCT
CGCCGACCTCACCCCCGCAAGGCGCCGCGCCTATGCGGTGATCGGCGACCGTGAGACGCTTCTGCGCGCGCGCGCCGCCT
GTGGCCTCGATCTGGCGCTGCACGAGTTCGGCGACGGGGCCCCCGAGGGCTCGGTCGCCGTGATCCACGAGGAGGTGGCC
GGCCTGCCGGGCCGCTTCGGGGTGCTCTCGCCCGCCTGCGGCGAGGCCTCGTTCCGCTACATCGACCGCGCCGTCACCAT
GACGCGCGGCGGCGAGGCCGCCTGCATCGTCACGGCACCGATCAACAAGGAGGCGCTGAACGCGGCCGGCCACCATTACG
ACGGCCACACCGGGATGCTCGCCCACCTCACGGGCTGCGCCGCCTCGTGGATGCTGCTCGCCTCGCCCACGCTGAACGTG
ATCCATGTCTCGACCCACATCTCGCTGAAGGAGGCCATCGGCCGGGCCACGCCCGAGCGGGTGCTCGAAACCATCCGCAC
CGGGCACCGGCACCTGCAGCGCATGGGGATCGCGCAGCCGCGGATCGCGGTGGCGGGGATCAACCCGCACTGCGGCGAGA
ACGGGCTCTTCGGACGCGAGGACGATCTGCAGGTGCAGCCGGCGGTCGAGGCCGCGCGGGCCGAGGGCATCGACGTGGTG
GGTCCGATCCCGGCCGATACGGTCTATTACCGCGCCCATTCCGGTGCCTTCGACCTCGTGGTGGCGCAGTATCACGATCA
GGGCCACATCCCGATCAAGCTCATCGCTTTCGACACGGCGGTCAACTGCTCGCTGGGGTTGCCCATCGACCGCTGCTCGG
TCGATCACGGCACCGCCTTCGACATCGCAGGCACCGGGCGGGCCAATCACGTCAACATGCTGGCGGCGCTGGCCTACGCG
GACAAGCTGGTCGCGGGCCGCGGCTGA

Upstream 100 bases:

>100_bases
GTGATCGAGGACATCCGCACCCTCATCGCCGGCGGACGCCCGGCGCGCTGCCTGAACGCGGCGGAGCTGGGCTGAGCCCG
GCCGAACAGGAGAAAGACCC

Downstream 100 bases:

>100_bases
CGGGGGGGCGGCTCCGGGGGACGCGCCCCCCGGAGCGCTGCCGCGCTCAGCGCATCCGGAGATCGAGGAGGCTCCCGCCG
AACAGGCGGTCGCGGGAATG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase 2

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 2 [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSSPQPIVITMGDPSGVGAEVTVKALADLTPARRRAYAVIGDRETLLRARAACGLDLALHEFGDGAPEGSVAVIHEEVA
GLPGRFGVLSPACGEASFRYIDRAVTMTRGGEAACIVTAPINKEALNAAGHHYDGHTGMLAHLTGCAASWMLLASPTLNV
IHVSTHISLKEAIGRATPERVLETIRTGHRHLQRMGIAQPRIAVAGINPHCGENGLFGREDDLQVQPAVEAARAEGIDVV
GPIPADTVYYRAHSGAFDLVVAQYHDQGHIPIKLIAFDTAVNCSLGLPIDRCSVDHGTAFDIAGTGRANHVNMLAALAYA
DKLVAGRG

Sequences:

>Translated_328_residues
MSSSPQPIVITMGDPSGVGAEVTVKALADLTPARRRAYAVIGDRETLLRARAACGLDLALHEFGDGAPEGSVAVIHEEVA
GLPGRFGVLSPACGEASFRYIDRAVTMTRGGEAACIVTAPINKEALNAAGHHYDGHTGMLAHLTGCAASWMLLASPTLNV
IHVSTHISLKEAIGRATPERVLETIRTGHRHLQRMGIAQPRIAVAGINPHCGENGLFGREDDLQVQPAVEAARAEGIDVV
GPIPADTVYYRAHSGAFDLVVAQYHDQGHIPIKLIAFDTAVNCSLGLPIDRCSVDHGTAFDIAGTGRANHVNMLAALAYA
DKLVAGRG
>Mature_327_residues
SSSPQPIVITMGDPSGVGAEVTVKALADLTPARRRAYAVIGDRETLLRARAACGLDLALHEFGDGAPEGSVAVIHEEVAG
LPGRFGVLSPACGEASFRYIDRAVTMTRGGEAACIVTAPINKEALNAAGHHYDGHTGMLAHLTGCAASWMLLASPTLNVI
HVSTHISLKEAIGRATPERVLETIRTGHRHLQRMGIAQPRIAVAGINPHCGENGLFGREDDLQVQPAVEAARAEGIDVVG
PIPADTVYYRAHSGAFDLVVAQYHDQGHIPIKLIAFDTAVNCSLGLPIDRCSVDHGTAFDIAGTGRANHVNMLAALAYAD
KLVAGRG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=34.6625766871166, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34415; Mature: 34283

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPQPIVITMGDPSGVGAEVTVKALADLTPARRRAYAVIGDRETLLRARAACGLDLAL
CCCCCCCEEEEECCCCCCCHHEEHHHHHCCCHHHHEEEEEECCHHHHHHHHHHCCCEEEH
HEFGDGAPEGSVAVIHEEVAGLPGRFGVLSPACGEASFRYIDRAVTMTRGGEAACIVTAP
HHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECC
INKEALNAAGHHYDGHTGMLAHLTGCAASWMLLASPTLNVIHVSTHISLKEAIGRATPER
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEECCCEEEEEEEECEEHHHHHCCCCHHH
VLETIRTGHRHLQRMGIAQPRIAVAGINPHCGENGLFGREDDLQVQPAVEAARAEGIDVV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEECHHHHHHHHCCCEEE
GPIPADTVYYRAHSGAFDLVVAQYHDQGHIPIKLIAFDTAVNCSLGLPIDRCSVDHGTAF
CCCCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECEECCEECCCHHHCCCCCCCEE
DIAGTGRANHVNMLAALAYADKLVAGRG
EEECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSSPQPIVITMGDPSGVGAEVTVKALADLTPARRRAYAVIGDRETLLRARAACGLDLAL
CCCCCCEEEEECCCCCCCHHEEHHHHHCCCHHHHEEEEEECCHHHHHHHHHHCCCEEEH
HEFGDGAPEGSVAVIHEEVAGLPGRFGVLSPACGEASFRYIDRAVTMTRGGEAACIVTAP
HHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECC
INKEALNAAGHHYDGHTGMLAHLTGCAASWMLLASPTLNVIHVSTHISLKEAIGRATPER
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEECCCEEEEEEEECEEHHHHHCCCCHHH
VLETIRTGHRHLQRMGIAQPRIAVAGINPHCGENGLFGREDDLQVQPAVEAARAEGIDVV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEECHHHHHHHHCCCEEE
GPIPADTVYYRAHSGAFDLVVAQYHDQGHIPIKLIAFDTAVNCSLGLPIDRCSVDHGTAF
CCCCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECEECCEECCCHHHCCCCCCCEE
DIAGTGRANHVNMLAALAYADKLVAGRG
EEECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]