Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 77465400

GI number: 77465400

Start: 462848

End: 463651

Strand: Reverse

Name: yafV [C]

Synonym: RSP_3399

Alternate gene names: 77465400

Gene position: 463651-462848 (Counterclockwise)

Preceding gene: 77465401

Following gene: 77465399

Centisome position: 49.17

GC content: 67.16

Gene sequence:

>804_bases
ATGAGAGTTAGCTTGATCCAGATGAATTCCGCCGAGAACAAGGAGCGGAATCTGGACGTGGCGGAGGAGATGATCCGCAA
GGCGGTCGGGGTCGAGAAACCCGACCTGGTGGTGCTGCCGGAATATTTCGCCTTCCTCGGCGAGGGGCGGGAGGCGGTCC
ACGGCAATGGCGAGGCCTTCCCGGAGGGGCCGACCTACCGGCGCTTCTCGGCGCTGGCGTCCGAACTGGGCGTGACGCTG
CATCTGGGCTCGATGGTCGAGAAGGCCGGGAACGGCCATTACAACACCACGCTCGTCTTCGGCCCCGACGGCGCCGAGAT
CGCCCGCTACCGCAAGATGCACCTCTTCGACATCGACGTGCCGGGCGGCATGTCCTACCGCGAGTCCGACACGATCAGCC
GCGGCGAGGAGGTCGTGACCTACCGGGTGGGCGAGACCACGGTCGGCTGCGCCATCTGCTACGACATCCGCTTCCCGGAA
CTCTTCCGCGCGCTGCGCGACAAGGGGGCGGAGGTGATCGTGCTGCCCGCGGCCTTCACGCTGATGACGGGCAAGGATCA
CTGGGAGGTGCTGGCGCGGGCGCGCGCCATCGAGACCCAGACCTATTTCCTCGCCGTGGGCCAGACCGGCTCGCATGCCG
AAGGGCGCAAATGGTGCTGGGGCCATACGATGGCGATCGACCCCTGGGGCCATGTCGTGGCCCAATGTTCCGACGGCGAG
GGTCTGACGACCGCCGTCGTCGATCCCGCCCGTATCGAGGCCGTCCGCCGTGACGTGCCCGTGGCCCAGCACCACGTTCT
CTGA

Upstream 100 bases:

>100_bases
GGGGGCGATAAGTTTTTCTGTTCGGACCCCACAAAAAAGAGTCGTTTGCCACGGAGCGGCCCGACAGGGAGCCTTGAACG
GAGAAAAGCAGGAGGCTCGC

Downstream 100 bases:

>100_bases
GGACTGCGCATGTTCACTGTCAACCAGATGCCCCCGCAGATCGCGCCGGCCCTCGTCGCGCGGATGGAGAAGGTGGAGGT
GGCCACCGTGGGTCACTTCC

Product: carbon-nitrogen hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MRVSLIQMNSAENKERNLDVAEEMIRKAVGVEKPDLVVLPEYFAFLGEGREAVHGNGEAFPEGPTYRRFSALASELGVTL
HLGSMVEKAGNGHYNTTLVFGPDGAEIARYRKMHLFDIDVPGGMSYRESDTISRGEEVVTYRVGETTVGCAICYDIRFPE
LFRALRDKGAEVIVLPAAFTLMTGKDHWEVLARARAIETQTYFLAVGQTGSHAEGRKWCWGHTMAIDPWGHVVAQCSDGE
GLTTAVVDPARIEAVRRDVPVAQHHVL

Sequences:

>Translated_267_residues
MRVSLIQMNSAENKERNLDVAEEMIRKAVGVEKPDLVVLPEYFAFLGEGREAVHGNGEAFPEGPTYRRFSALASELGVTL
HLGSMVEKAGNGHYNTTLVFGPDGAEIARYRKMHLFDIDVPGGMSYRESDTISRGEEVVTYRVGETTVGCAICYDIRFPE
LFRALRDKGAEVIVLPAAFTLMTGKDHWEVLARARAIETQTYFLAVGQTGSHAEGRKWCWGHTMAIDPWGHVVAQCSDGE
GLTTAVVDPARIEAVRRDVPVAQHHVL
>Mature_267_residues
MRVSLIQMNSAENKERNLDVAEEMIRKAVGVEKPDLVVLPEYFAFLGEGREAVHGNGEAFPEGPTYRRFSALASELGVTL
HLGSMVEKAGNGHYNTTLVFGPDGAEIARYRKMHLFDIDVPGGMSYRESDTISRGEEVVTYRVGETTVGCAICYDIRFPE
LFRALRDKGAEVIVLPAAFTLMTGKDHWEVLARARAIETQTYFLAVGQTGSHAEGRKWCWGHTMAIDPWGHVVAQCSDGE
GLTTAVVDPARIEAVRRDVPVAQHHVL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=271, Percent_Identity=39.4833948339483, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI297632348, Length=271, Percent_Identity=39.4833948339483, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI297632350, Length=271, Percent_Identity=39.4833948339483, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=35.9550561797753, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI297632346, Length=196, Percent_Identity=34.1836734693878, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=38.4328358208955, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323383, Length=271, Percent_Identity=35.0553505535055, Blast_Score=169, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6322335, Length=296, Percent_Identity=32.4324324324324, Blast_Score=159, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21355835, Length=262, Percent_Identity=37.7862595419847, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI17933642, Length=262, Percent_Identity=36.2595419847328, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29474; Mature: 29474

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSLIQMNSAENKERNLDVAEEMIRKAVGVEKPDLVVLPEYFAFLGEGREAVHGNGEAF
CEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCCEECCCCCCC
PEGPTYRRFSALASELGVTLHLGSMVEKAGNGHYNTTLVFGPDGAEIARYRKMHLFDIDV
CCCCCHHHHHHHHHHCCEEEEHHHHHHHCCCCCEEEEEEECCCCHHHHHHEEEEEEEEEC
PGGMSYRESDTISRGEEVVTYRVGETTVGCAICYDIRFPELFRALRDKGAEVIVLPAAFT
CCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCEEEEEECEEE
LMTGKDHWEVLARARAIETQTYFLAVGQTGSHAEGRKWCWGHTMAIDPWGHVVAQCSDGE
EECCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEEECCCEEECCHHHEEEEECCCC
GLTTAVVDPARIEAVRRDVPVAQHHVL
CCEEEEECHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MRVSLIQMNSAENKERNLDVAEEMIRKAVGVEKPDLVVLPEYFAFLGEGREAVHGNGEAF
CEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCCEECCCCCCC
PEGPTYRRFSALASELGVTLHLGSMVEKAGNGHYNTTLVFGPDGAEIARYRKMHLFDIDV
CCCCCHHHHHHHHHHCCEEEEHHHHHHHCCCCCEEEEEEECCCCHHHHHHEEEEEEEEEC
PGGMSYRESDTISRGEEVVTYRVGETTVGCAICYDIRFPELFRALRDKGAEVIVLPAAFT
CCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCEEEEEECEEE
LMTGKDHWEVLARARAIETQTYFLAVGQTGSHAEGRKWCWGHTMAIDPWGHVVAQCSDGE
EECCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEEECCCEEECCHHHEEEEECCCC
GLTTAVVDPARIEAVRRDVPVAQHHVL
CCEEEEECHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]