| Definition | Rhodobacter sphaeroides 2.4.1 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007494 |
| Length | 943,016 |
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The map label for this gene is livF [H]
Identifier: 77465300
GI number: 77465300
Start: 354469
End: 355167
Strand: Reverse
Name: livF [H]
Synonym: RSP_3295
Alternate gene names: 77465300
Gene position: 355167-354469 (Counterclockwise)
Preceding gene: 77465301
Following gene: 77465299
Centisome position: 37.66
GC content: 66.38
Gene sequence:
>699_bases ATGACGCTCCTGGAGGTCAACGGCCTTCACGCCTGGTATGGCGAGAGCCACATCCTGCACGGGGTGGATCTGTTCGTCGA GGAAGGCGAGACGATCTGCATCCTCGGTCGCAACGGCATGGGCAAGACCACGACGCTGCGCACGATCATGGGGATCCTGA GGAAGCGCACCGGGGCGATCCGGTTCGCGGGCAAGGACATGATGGGCGTGCCGCTGCATCGCACCGCCCGCGAGGGTCTG GGCTTCGTGCCCGAGGAACGGGGCATCTTCGCCACGCTCTCGGTCGAGGAGAACCTGATGCTGCCCCCGGTGGTCGCCAA GGGCGGCATGTCGGTGGGCGAGATCTACGAGCTGTTTCCGAACCTGAAGGAGCGGCGCTCGAGCCCCGGCACCAAGCTGT CGGGCGGCGAGCAGCAGATGCTCGCCATGGCGCGGATCCTGCGCACCGGCGCGCGCTGCCTGTTGCTGGACGAGCCGACC GAGGGGCTCGCCCCGGTCATCATCCAGCGCATCGGCGAGGTGCTGATCGAGCTGCGCGACCGCGGGATGACCGTGGTGCT GGTCGAGCAGAATTTCCGCTTCGCCTCGAAGGTTGCGGACCGTTTCTACCTCATGGACCACGGACAGATGGTGGCGGATT TCCCGGTCGAGGAGCTGCCCGCGAACATGCCGATGCTGAATTCGGTGCTGGGGGTGTGA
Upstream 100 bases:
>100_bases TGACGGTGCTGCAGCGGGGCGAGATCCTCGCCCACGGCGACTATGCCACCGTGAGCACCGATCCGCGCGTGCGCACGGCC TATATGGGAACGGAGGACGC
Downstream 100 bases:
>100_bases GATGATGACGATCTTCGGCATTCCGACGGCGGCCCTCTTCGGCCAGCTGCTGGTGGGTCTCATCAACGGCTCGTTCTATG CGCTCCTGTCGCTGGGGCTT
Product: ABC branched-chain amino acid transporter, ATPase subunit
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 232; Mature: 231
Protein sequence:
>232_residues MTLLEVNGLHAWYGESHILHGVDLFVEEGETICILGRNGMGKTTTLRTIMGILRKRTGAIRFAGKDMMGVPLHRTAREGL GFVPEERGIFATLSVEENLMLPPVVAKGGMSVGEIYELFPNLKERRSSPGTKLSGGEQQMLAMARILRTGARCLLLDEPT EGLAPVIIQRIGEVLIELRDRGMTVVLVEQNFRFASKVADRFYLMDHGQMVADFPVEELPANMPMLNSVLGV
Sequences:
>Translated_232_residues MTLLEVNGLHAWYGESHILHGVDLFVEEGETICILGRNGMGKTTTLRTIMGILRKRTGAIRFAGKDMMGVPLHRTAREGL GFVPEERGIFATLSVEENLMLPPVVAKGGMSVGEIYELFPNLKERRSSPGTKLSGGEQQMLAMARILRTGARCLLLDEPT EGLAPVIIQRIGEVLIELRDRGMTVVLVEQNFRFASKVADRFYLMDHGQMVADFPVEELPANMPMLNSVLGV >Mature_231_residues TLLEVNGLHAWYGESHILHGVDLFVEEGETICILGRNGMGKTTTLRTIMGILRKRTGAIRFAGKDMMGVPLHRTAREGLG FVPEERGIFATLSVEENLMLPPVVAKGGMSVGEIYELFPNLKERRSSPGTKLSGGEQQMLAMARILRTGARCLLLDEPTE GLAPVIIQRIGEVLIELRDRGMTVVLVEQNFRFASKVADRFYLMDHGQMVADFPVEELPANMPMLNSVLGV
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI21536376, Length=197, Percent_Identity=30.9644670050761, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI45446740, Length=202, Percent_Identity=28.7128712871287, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI47078218, Length=202, Percent_Identity=28.7128712871287, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI27881501, Length=212, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI30795238, Length=212, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI9961250, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4505771, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI9961252, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI105990541, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI31657092, Length=205, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI153792144, Length=200, Percent_Identity=26.5, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI27436953, Length=198, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI42741659, Length=171, Percent_Identity=30.9941520467836, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI116734710, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI150417984, Length=200, Percent_Identity=29, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI255708477, Length=157, Percent_Identity=29.9363057324841, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI148612844, Length=157, Percent_Identity=29.9363057324841, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI27477115, Length=201, Percent_Identity=28.8557213930348, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082268, Length=232, Percent_Identity=41.8103448275862, Blast_Score=172, Evalue=1e-44, Organism=Escherichia coli, GI1789593, Length=219, Percent_Identity=34.2465753424658, Blast_Score=117, Evalue=5e-28, Organism=Escherichia coli, GI1789672, Length=232, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1787029, Length=228, Percent_Identity=31.140350877193, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=33.1838565022422, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=31.5068493150685, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1788450, Length=218, Percent_Identity=30.2752293577982, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787105, Length=229, Percent_Identity=31.8777292576419, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1787792, Length=225, Percent_Identity=28.4444444444444, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1786872, Length=224, Percent_Identity=33.4821428571429, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1788761, Length=225, Percent_Identity=31.1111111111111, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789864, Length=252, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI48995001, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1790190, Length=229, Percent_Identity=24.8908296943231, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI1788897, Length=225, Percent_Identity=28.4444444444444, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786253, Length=224, Percent_Identity=29.4642857142857, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788472, Length=223, Percent_Identity=26.9058295964126, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI87081791, Length=217, Percent_Identity=29.4930875576037, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789991, Length=218, Percent_Identity=25.2293577981651, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786703, Length=227, Percent_Identity=30.3964757709251, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1790525, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081834, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI87081782, Length=226, Percent_Identity=28.7610619469027, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1788644, Length=243, Percent_Identity=28.8065843621399, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1787112, Length=215, Percent_Identity=33.0232558139535, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1786398, Length=209, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=28.169014084507, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI48994997, Length=229, Percent_Identity=29.6943231441048, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1787712, Length=214, Percent_Identity=28.0373831775701, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1790467, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787500, Length=227, Percent_Identity=24.2290748898678, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1788210, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=28.110599078341, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788165, Length=222, Percent_Identity=25.2252252252252, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1790739, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI48994943, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=25.3456221198157, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787164, Length=218, Percent_Identity=28.8990825688073, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789032, Length=222, Percent_Identity=25.6756756756757, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17510237, Length=219, Percent_Identity=31.0502283105023, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71983510, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI71983523, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71983516, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71984940, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193211017, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193211015, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71996809, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17565586, Length=216, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25146777, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115533608, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI212646699, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193202349, Length=212, Percent_Identity=27.3584905660377, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17541710, Length=155, Percent_Identity=31.6129032258064, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71992285, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6323217, Length=207, Percent_Identity=24.6376811594203, Blast_Score=63, Evalue=3e-11, Organism=Drosophila melanogaster, GI24648314, Length=213, Percent_Identity=28.169014084507, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=25.5924170616114, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI221512771, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI85725262, Length=217, Percent_Identity=29.4930875576037, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24582014, Length=236, Percent_Identity=28.3898305084746, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24582012, Length=236, Percent_Identity=28.3898305084746, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24650853, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24650855, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI281362751, Length=215, Percent_Identity=28.8372093023256, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI19920532, Length=212, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580930, Length=212, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28574150, Length=217, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007328, Length=217, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221500365, Length=216, Percent_Identity=24.537037037037, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI116007184, Length=216, Percent_Identity=24.537037037037, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24643674, Length=215, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28573573, Length=222, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI17136662, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21357907, Length=162, Percent_Identity=30.8641975308642, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28573571, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI281363262, Length=212, Percent_Identity=26.8867924528302, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 25607; Mature: 25475
Theoretical pI: Translated: 6.37; Mature: 6.37
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 6.0 %Met (Translated Protein) 6.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 5.6 %Met (Mature Protein) 6.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLLEVNGLHAWYGESHILHGVDLFVEEGETICILGRNGMGKTTTLRTIMGILRKRTGAI CEEEEECCCEEECCCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE RFAGKDMMGVPLHRTAREGLGFVPEERGIFATLSVEENLMLPPVVAKGGMSVGEIYELFP EECCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHC NLKERRSSPGTKLSGGEQQMLAMARILRTGARCLLLDEPTEGLAPVIIQRIGEVLIELRD CHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC RGMTVVLVEQNFRFASKVADRFYLMDHGQMVADFPVEELPANMPMLNSVLGV CCCEEEEEECCCHHHHHHHHHEEEEECCCEEECCCHHHCCCCCCHHHHHHCC >Mature Secondary Structure TLLEVNGLHAWYGESHILHGVDLFVEEGETICILGRNGMGKTTTLRTIMGILRKRTGAI EEEEECCCEEECCCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE RFAGKDMMGVPLHRTAREGLGFVPEERGIFATLSVEENLMLPPVVAKGGMSVGEIYELFP EECCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHC NLKERRSSPGTKLSGGEQQMLAMARILRTGARCLLLDEPTEGLAPVIIQRIGEVLIELRD CHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC RGMTVVLVEQNFRFASKVADRFYLMDHGQMVADFPVEELPANMPMLNSVLGV CCCEEEEEECCCHHHHHHHHHEEEEECCCEEECCCHHHCCCCCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]