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The map label for this gene is appB [H]

Identifier: 77465258

GI number: 77465258

Start: 308953

End: 309891

Strand: Reverse

Name: appB [H]

Synonym: RSP_3251

Alternate gene names: 77465258

Gene position: 309891-308953 (Counterclockwise)

Preceding gene: 77465259

Following gene: 77465257

Centisome position: 32.86

GC content: 68.8

Gene sequence:

>939_bases
ATGCACCGCTACCGCTTCGTGCTCTTCCGCCCGCTCCAGTTCCTGCCCGTGCTCTTCGGCATCTCGGTCATCACCTTCGT
GCTGGTGCGGCTGATCCCCGGAGATCCCGCGCGCATCCTGCTCGGCACCCGCGCCACGCCCACGGCGCTCGCCCGGATCC
GCGCGCAATACGGCCTCGATGAGCCGATGTGGGCGCAGTATCTCTATTTCCTGAAGAACCTCGCTTCCGGCGAGATGGGC
CGCTCGACCCTCTACAAGATCGACGTCCTGCCGCTGATCGCCACGCGGATCGAGCCGACGCTCGCGCTCGTGACCATGGG
CGTCCTCCTCTCGCTCGCCATCGCCGTTCCCTTCGCCGCCATCTCGGCCCGGCGGCAGGGCCGGGCGGCGGATCAGGCGG
TGCGGGTCGTCTCGACGCTGGGGATCGGCTTTCCGCCCTTCTGGCTGGGCCTCGTGCTGATCCTGCTCTTCAGCGTCACG
CTGGGCTGGCTGCCGGTTTCGGGCTACGGCGAGACGCTGGGCGAGAAGATCTCGCACCTGATCCTGCCGGGGCTGACGGT
GGCGCTGTCGCTCTCGGCGGTGCTGACGCGCAGCCTGCGGGCGGGCATGATCGCGGGGATCCATTCCGATGTGGCCACCG
CCGCCCGCGCCCGCGGCCTGTCGGAGAATGCGGTCTTCTGGCGCCATGTGGTGCCGAACGCGCTGGTGCCCACGGTGAAC
CTTCTCGCCGTCAACATCGGCTGGCTGATCGGCGGCACCGTGGTGGTCGAGAGCGTCTTCGCCCTGCCCGGCATGGGGCA
GCTTCTGGTGCGGGGCATCTTCTCGCGCGACTACATGGTGGTGCAGGGCGTGGCCATGACCTTCGCGGTCGCCACGGTTC
TGGTGAACTTCCTGGCCGACATCGTGACGGTCGCCCTCGACCCGCGGGTGAAGCTGTGA

Upstream 100 bases:

>100_bases
CCAGCGGCCCTGCGCCGGGCGAAGGGCTGTTTCTTTAAGGAGCCTCATGACTTGCCCTCGTCCCGGCCTCTGCGCCGCCC
GGACCCGCTGAGGGAGCGCC

Downstream 100 bases:

>100_bases
TCGCCGCGCTCGGCCTGCCCGTCCGCCGCCGCCCGATGCTGGCCATCGGGACCGCGCTCCTTCTGGCCTTCCTCCTCGCG
GCGCTGCTCGCGCCCTGGAT

Product: ABC peptide transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MHRYRFVLFRPLQFLPVLFGISVITFVLVRLIPGDPARILLGTRATPTALARIRAQYGLDEPMWAQYLYFLKNLASGEMG
RSTLYKIDVLPLIATRIEPTLALVTMGVLLSLAIAVPFAAISARRQGRAADQAVRVVSTLGIGFPPFWLGLVLILLFSVT
LGWLPVSGYGETLGEKISHLILPGLTVALSLSAVLTRSLRAGMIAGIHSDVATAARARGLSENAVFWRHVVPNALVPTVN
LLAVNIGWLIGGTVVVESVFALPGMGQLLVRGIFSRDYMVVQGVAMTFAVATVLVNFLADIVTVALDPRVKL

Sequences:

>Translated_312_residues
MHRYRFVLFRPLQFLPVLFGISVITFVLVRLIPGDPARILLGTRATPTALARIRAQYGLDEPMWAQYLYFLKNLASGEMG
RSTLYKIDVLPLIATRIEPTLALVTMGVLLSLAIAVPFAAISARRQGRAADQAVRVVSTLGIGFPPFWLGLVLILLFSVT
LGWLPVSGYGETLGEKISHLILPGLTVALSLSAVLTRSLRAGMIAGIHSDVATAARARGLSENAVFWRHVVPNALVPTVN
LLAVNIGWLIGGTVVVESVFALPGMGQLLVRGIFSRDYMVVQGVAMTFAVATVLVNFLADIVTVALDPRVKL
>Mature_312_residues
MHRYRFVLFRPLQFLPVLFGISVITFVLVRLIPGDPARILLGTRATPTALARIRAQYGLDEPMWAQYLYFLKNLASGEMG
RSTLYKIDVLPLIATRIEPTLALVTMGVLLSLAIAVPFAAISARRQGRAADQAVRVVSTLGIGFPPFWLGLVLILLFSVT
LGWLPVSGYGETLGEKISHLILPGLTVALSLSAVLTRSLRAGMIAGIHSDVATAARARGLSENAVFWRHVVPNALVPTVN
LLAVNIGWLIGGTVVVESVFALPGMGQLLVRGIFSRDYMVVQGVAMTFAVATVLVNFLADIVTVALDPRVKL

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=307, Percent_Identity=35.5048859934853, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=37.4193548387097, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1789965, Length=334, Percent_Identity=31.1377245508982, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787497, Length=309, Percent_Identity=32.0388349514563, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787761, Length=318, Percent_Identity=35.5345911949685, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=25.7352941176471, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788504, Length=358, Percent_Identity=23.463687150838, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33693; Mature: 33693

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRYRFVLFRPLQFLPVLFGISVITFVLVRLIPGDPARILLGTRATPTALARIRAQYGLD
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
EPMWAQYLYFLKNLASGEMGRSTLYKIDVLPLIATRIEPTLALVTMGVLLSLAIAVPFAA
CHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISARRQGRAADQAVRVVSTLGIGFPPFWLGLVLILLFSVTLGWLPVSGYGETLGEKISHL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ILPGLTVALSLSAVLTRSLRAGMIAGIHSDVATAARARGLSENAVFWRHVVPNALVPTVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHH
LLAVNIGWLIGGTVVVESVFALPGMGQLLVRGIFSRDYMVVQGVAMTFAVATVLVNFLAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IVTVALDPRVKL
HHHHHCCCCCCC
>Mature Secondary Structure
MHRYRFVLFRPLQFLPVLFGISVITFVLVRLIPGDPARILLGTRATPTALARIRAQYGLD
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
EPMWAQYLYFLKNLASGEMGRSTLYKIDVLPLIATRIEPTLALVTMGVLLSLAIAVPFAA
CHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISARRQGRAADQAVRVVSTLGIGFPPFWLGLVLILLFSVTLGWLPVSGYGETLGEKISHL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ILPGLTVALSLSAVLTRSLRAGMIAGIHSDVATAARARGLSENAVFWRHVVPNALVPTVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHH
LLAVNIGWLIGGTVVVESVFALPGMGQLLVRGIFSRDYMVVQGVAMTFAVATVLVNFLAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IVTVALDPRVKL
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]