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The map label for this gene is yrpG [H]

Identifier: 77465215

GI number: 77465215

Start: 254301

End: 255320

Strand: Reverse

Name: yrpG [H]

Synonym: RSP_3201

Alternate gene names: 77465215

Gene position: 255320-254301 (Counterclockwise)

Preceding gene: 77465226

Following gene: 77465205

Centisome position: 27.07

GC content: 69.41

Gene sequence:

>1020_bases
ATGCGTTACCGTCGTCTCGGCCCGAGCGGCCTTTTTGTCTCCGAGCTCTGCCTCGGCACCATGACCTTCGGCGGCTCGGA
CGGCATCTGGGGCCAGATCGGTCAGCTCGGACAGGACGAGGCGGATGCGCTGGTGCGCACCGCGCTCGATGCGGGCATCA
ATTTCATCGACACGGCCAATGTCTATGCGGGCGGCGAGAGCGAGCGCATCCTCGGCCGGTCGCTGCGCAACCTCGGGGTG
CGGCGCGAGGATGTGGTGATCGCGACCAAGGTGCTCGGGCCCATGGGCGCAGGCGTCAATGCGCGCGGGGCCTCGCGCGT
CCATATCCTCGATCAGTGCAAGGCCAGCCTCGAGCGGCTGCAGCTCGACCATATCGACCTCTATCAGATCCACGGGTTCG
ACGCCGAGACCCCCATCGTGGAGACGCTGGAGGCGCTCGACACGCTCGTGCGCCACGGCCATGTCCGCTACATCGGCCTG
TCGAACTGGGCGGCCTGGCAGGTGATGAAGGCGGTGGGGATCGCCGAGGCGCGCCGTCTGGCGCCGATCCTGTCGCTTCA
GGCCTATTACACTCTGGCCGGCCGCGATCTCGAGCGCGAGGTGGTGCCGATGCTGAAGGACACGGGCATGGGCCTCATGG
TCTGGAGCCCGCTGGCGGGCGGCTTCCTGTCGGGAAAGTACGACCGCGAGGGCAAGGCCGCCGACGGGCGCCGCGCGGCC
TTCGACTTCCCGCCGGTCGACAAGGATCGCGGCTGGACCGTGATCGAGGCGATGCGCCCCATCGCGGAGGCGAAGGGCTC
GTCTGTCGCGCAGGTGGCGCTGGCCTGGCTCCTGCATCAGGAGGCGGTCACGAGCGTGATCGTGGGGGCCAAGCGCGTGG
ATCAGCTGGCCGACAACATCGCCGCGACCGAGGTGCGGCTCGAGGCCGAGGATCTGGCGGCGCTCGACCGGGCGAGCGCG
CTGGCGCCGGAATATCCGGGCTGGATGCTCGAGCGGCAGCGGAGCTACCGCGCCCGGTAG

Upstream 100 bases:

>100_bases
GCATTTCGAGAGGATCGGCGTCGCGGGAACCGGCCCCTCTGCCCCATGTTCGGAAACGTGGCGGAGCCAGCGCCCGGCCG
ACAAGGAAAGGATTTCATCC

Downstream 100 bases:

>100_bases
GCCGCTCCGGAGCCTGCCGCCGCGGACCCGCGGTCTGCGGCGGCGCCCCGGGCGGGCCCGCGGCCAAGGCCAGCTCGTCC
ACCATCGCCGTGACGGCTCC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRYRRLGPSGLFVSELCLGTMTFGGSDGIWGQIGQLGQDEADALVRTALDAGINFIDTANVYAGGESERILGRSLRNLGV
RREDVVIATKVLGPMGAGVNARGASRVHILDQCKASLERLQLDHIDLYQIHGFDAETPIVETLEALDTLVRHGHVRYIGL
SNWAAWQVMKAVGIAEARRLAPILSLQAYYTLAGRDLEREVVPMLKDTGMGLMVWSPLAGGFLSGKYDREGKAADGRRAA
FDFPPVDKDRGWTVIEAMRPIAEAKGSSVAQVALAWLLHQEAVTSVIVGAKRVDQLADNIAATEVRLEAEDLAALDRASA
LAPEYPGWMLERQRSYRAR

Sequences:

>Translated_339_residues
MRYRRLGPSGLFVSELCLGTMTFGGSDGIWGQIGQLGQDEADALVRTALDAGINFIDTANVYAGGESERILGRSLRNLGV
RREDVVIATKVLGPMGAGVNARGASRVHILDQCKASLERLQLDHIDLYQIHGFDAETPIVETLEALDTLVRHGHVRYIGL
SNWAAWQVMKAVGIAEARRLAPILSLQAYYTLAGRDLEREVVPMLKDTGMGLMVWSPLAGGFLSGKYDREGKAADGRRAA
FDFPPVDKDRGWTVIEAMRPIAEAKGSSVAQVALAWLLHQEAVTSVIVGAKRVDQLADNIAATEVRLEAEDLAALDRASA
LAPEYPGWMLERQRSYRAR
>Mature_339_residues
MRYRRLGPSGLFVSELCLGTMTFGGSDGIWGQIGQLGQDEADALVRTALDAGINFIDTANVYAGGESERILGRSLRNLGV
RREDVVIATKVLGPMGAGVNARGASRVHILDQCKASLERLQLDHIDLYQIHGFDAETPIVETLEALDTLVRHGHVRYIGL
SNWAAWQVMKAVGIAEARRLAPILSLQAYYTLAGRDLEREVVPMLKDTGMGLMVWSPLAGGFLSGKYDREGKAADGRRAA
FDFPPVDKDRGWTVIEAMRPIAEAKGSSVAQVALAWLLHQEAVTSVIVGAKRVDQLADNIAATEVRLEAEDLAALDRASA
LAPEYPGWMLERQRSYRAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=38.7301587301587, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=38.6581469648562, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI27436964, Length=315, Percent_Identity=36.5079365079365, Blast_Score=185, Evalue=4e-47,
Organism=Homo sapiens, GI27436962, Length=315, Percent_Identity=36.5079365079365, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI27436966, Length=315, Percent_Identity=36.1904761904762, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI27436971, Length=315, Percent_Identity=34.9206349206349, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI223718702, Length=307, Percent_Identity=30.9446254071661, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI41327764, Length=300, Percent_Identity=32, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI41152114, Length=279, Percent_Identity=31.8996415770609, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI223718708, Length=135, Percent_Identity=34.8148148148148, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=37.7708978328173, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=31.5315315315315, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=31.4540059347181, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788081, Length=276, Percent_Identity=29.3478260869565, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=27.5641025641026, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082198, Length=301, Percent_Identity=24.9169435215947, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786400, Length=303, Percent_Identity=27.3927392739274, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994888, Length=284, Percent_Identity=25, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=311, Percent_Identity=25.7234726688103, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=31.1178247734139, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323998, Length=327, Percent_Identity=29.9694189602446, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=29.1803278688525, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=324, Percent_Identity=28.0864197530864, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=28.2352941176471, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=161, Percent_Identity=32.9192546583851, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=354, Percent_Identity=27.683615819209, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45549126, Length=354, Percent_Identity=27.683615819209, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24646159, Length=231, Percent_Identity=32.9004329004329, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646155, Length=229, Percent_Identity=34.061135371179, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36980; Mature: 36980

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRRLGPSGLFVSELCLGTMTFGGSDGIWGQIGQLGQDEADALVRTALDAGINFIDTAN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCEEECCC
VYAGGESERILGRSLRNLGVRREDVVIATKVLGPMGAGVNARGASRVHILDQCKASLERL
EEECCCCHHHHHHHHHHCCCCCHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QLDHIDLYQIHGFDAETPIVETLEALDTLVRHGHVRYIGLSNWAAWQVMKAVGIAEARRL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
APILSLQAYYTLAGRDLEREVVPMLKDTGMGLMVWSPLAGGFLSGKYDREGKAADGRRAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
FDFPPVDKDRGWTVIEAMRPIAEAKGSSVAQVALAWLLHQEAVTSVIVGAKRVDQLADNI
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATEVRLEAEDLAALDRASALAPEYPGWMLERQRSYRAR
HHHHEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRYRRLGPSGLFVSELCLGTMTFGGSDGIWGQIGQLGQDEADALVRTALDAGINFIDTAN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCEEECCC
VYAGGESERILGRSLRNLGVRREDVVIATKVLGPMGAGVNARGASRVHILDQCKASLERL
EEECCCCHHHHHHHHHHCCCCCHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QLDHIDLYQIHGFDAETPIVETLEALDTLVRHGHVRYIGLSNWAAWQVMKAVGIAEARRL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
APILSLQAYYTLAGRDLEREVVPMLKDTGMGLMVWSPLAGGFLSGKYDREGKAADGRRAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
FDFPPVDKDRGWTVIEAMRPIAEAKGSSVAQVALAWLLHQEAVTSVIVGAKRVDQLADNI
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATEVRLEAEDLAALDRASALAPEYPGWMLERQRSYRAR
HHHHEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]