Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 77461924

GI number: 77461924

Start: 6394353

End: 6395093

Strand: Reverse

Name: ompR [H]

Synonym: Pfl01_5704

Alternate gene names: 77461924

Gene position: 6395093-6394353 (Counterclockwise)

Preceding gene: 77461928

Following gene: 77461923

Centisome position: 99.33

GC content: 60.86

Gene sequence:

>741_bases
ATGGAGCATGTCGATCACATTCTGATCGTCGACGACGACCGCGAAATTCGTGAACTGGTCGGCAATTACCTGAAGAAAAA
CGGCCTGCGCACCACGGTGGTTGCCGATGGCCGCCAGATGCGCAGTTTCCTGGAAGCCAACACCGTCGACCTGATCGTGC
TCGACATCATGATGCCCGGCGACGATGGCCTGCTGCTGTGCCGCGAGTTACGCTCGAGCAAACACAGGGCCACGCCGATC
CTGATGCTCACCGCGCGCAATGATGAAACCGACCGCATCCTCGGCCTGGAAATGGGCGCCGACGACTACCTGACTAAACC
GTTCGCCGCGCGCGAGCTGCTGGCGCGGATCAATGCCGTGCTGCGTCGTACACGGATGCTGCCGCCGAATCTGGTGGTGA
CTGAAAGCGGTCGGCTGCTGGCGTTCGGTCGCTGGCAGCTCGACACATCAGCCCGGCATCTGCTGGACAAGGACGGCACT
CTAGTTGCCCTAAGTGGCGGTGAATATCGTTTGTTGCGCGTATTCCTCGACCATCCGCAACGGGTGCTGAGCCGCGATCA
ATTGCTCAATCTGACCCAGGGTCGCGACGCCGATCTGTTCGACCGCTCCATCGATCTGCTGGTCAGCCGTCTGCGCCAGC
GCCTGCTGGATGACGCCCGTGAACCGGCCTACATCAAGACCGTACGCAGCGAAGGCTATGTGTTCTCGCTACCGGTCGAA
ATCCTTGGAGCTCCCGCATGA

Upstream 100 bases:

>100_bases
CTCCCTGATGCCAAATACAGTTCATTACCAATGCAGCAAGGCGAGCTGGGATCGTCTTTATAGACTGCACGGCAACCCCC
TTTGATTGAGGTTTGGCCCA

Downstream 100 bases:

>100_bases
ATCTCGCTCTGCGCTGGCCGCGTACCCTTGCCTCCAGATTATCGCTGATATTCCTGATCGGCCTGATCCTCGCTCAGGCG
CTGTCATTTAGCGCGCAATA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSSKHRATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
LVALSGGEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
ILGAPA

Sequences:

>Translated_246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSSKHRATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
LVALSGGEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
ILGAPA
>Mature_246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSSKHRATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
LVALSGGEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
ILGAPA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=44.6808510638298, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=37.1794871794872, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=38.961038961039, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=37.2881355932203, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=36.1344537815126, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=36.2869198312236, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.5, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.1877729257642, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=35.8974358974359, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.2068965517241, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=33.1877729257642, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.1888412017167, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.0434782608696, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.9130434782609, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=34.8623853211009, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=32.7433628318584, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=32.520325203252, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=104, Percent_Identity=37.5, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27924; Mature: 27924

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEEEEEEECC
DDGLLLCRELRSSKHRATPILMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGTLVALSGGEYRLLRVFLDHPQ
HHHHHCCCCCEEEECCCCEEEEEEEEECHHHHHHHCCCCCEEEECCCCEEEHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHH
ILGAPA
HCCCCC
>Mature Secondary Structure
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEEEEEEECC
DDGLLLCRELRSSKHRATPILMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGTLVALSGGEYRLLRVFLDHPQ
HHHHHCCCCCEEEECCCCEEEEEEEEECHHHHHHHCCCCCEEEECCCCEEEHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHH
ILGAPA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]