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The map label for this gene is copB [H]

Identifier: 77461887

GI number: 77461887

Start: 6347856

End: 6349763

Strand: Reverse

Name: copB [H]

Synonym: Pfl01_5667

Alternate gene names: 77461887

Gene position: 6349763-6347856 (Counterclockwise)

Preceding gene: 77461888

Following gene: 77461886

Centisome position: 98.62

GC content: 63.84

Gene sequence:

>1908_bases
ATGACTGCCACTACCTCAGCTCCGAGCCTGTTGTCCTCGGCCGAACAACGCCGCGCCGCCCGCCAGTTGACCCTGGCGAT
GCTCGCCCTCGGCTTGCTTGGTCTGGGGTTGATCTGGCGCTGGTTGATGCCGGAACAGTCGGGCGTCAGTCAGTTGTTGC
TCGGATTCGCTTCTTTATTAGTCGCGGTGCCGGTAATGCGTTCGGCCTGGTTCAGCCTGCGTTATCCGAGCCTGCACGGC
ATCACCGATCAGTTGATCGCCCTGGCGATGATAGGGGCCTGGGCCACGGGCGATCTGCTCACGGCAGCGCTGTTGCCGAT
CATCATGATCTTCGGCCACGTGCTGGAAGAGCGCAGTGTGATCGGCTCCCAGGAAGCGATTCATGCCCTCGGCCAACTGA
CGCGCAGCCATGCGCGCAAGGTGCAGGCGGACGGCTCGATCATCGAGGTCGACAACGGCACGCTCAAAGCTGGAGACAAA
GTGGAAGTGCGCGCCGGGGATCGGGTGCCGGCGGACGGTCGGGTTTTATCCGGCCAGGCCAGCCTCGACACGGCGTCGAT
CACCGGTGAATCGGTGCCGGTGGAGGCGGGTGTCGGCATGGCGGTGTTCGGCGGTGCGATCAACCTCGACGGGCTGTTGC
GAATCGAAGTGACCCGTACCGGGGATGAATCGACCCTCGGCAAAGTCATCGCGCTGATGCAGAACGCTGAACGCTCCAAA
CCGCCGATTACGCGTTTGCTCGAACGCTATGCCGGCAGTTACATGGTGCTGGTGTTGTTGCTCGCGGCGGTGACCTGGTT
TATCACCAACGATGCACAGGCGATGCTCGCGGTGCTGGTGGCGGCATGCCCATGCGCGCTGGTGTTGTCGGCGCCGGCCA
CGGCGATTGCCGGGGTGGCAGTGGCGGCGCGGCACGGGATCCTGATCCGCAGTTCGGCATTCCTTGAGGAATTGGCGGAT
CTCACTTCGCTGGTCGTCGACAAGACCGGAACCCTGACGTACGGCACGCTGCGCTTGCAGTCGATCAACAGCCCGCGAGC
GGATCATGGGTCGGTGATGGCGCTGGCTGCAAGCCTGGGTGCGGCGAGCAGCCATCCGGTCAGCCGCGCGCTGGCCGGAC
TGGTCAGCGCGGAAGAGGTGCTGGTGCTGACCGATATTCATGAGCGGCAGGGGTTGGGCGTAGTGGCCAAGACCGCGCAA
GGTGAAGCAGCGCTCGGGCGCCCGGAGCTGTTTGCACAGTTGGGCATCCCGACCACGGCGATCCCCGAACACGATGGCCC
GATTGCCGGGTTGGCGCTGAACGGCGAATTCCTTGCCTGGCTGTTGCTGGCCGACACCGTCAAACCGGAAGCTCGATTTG
CCCTGAGTGAACTGCGTGACCTCGGATTGGGACGACAACTGCTGTTGACCGGCGACCGGCAAAGCGTCGCGCAGACACTG
GCCAAGGATGTAGGCCTGCACGAAGTCGAAGCCCAGGCGTTGCCCGAAGACAAACTCAACCGAGTGCTCAAGGAAATCGA
CAACGGCTTCCGGCCGATGGTGGTCGGCGACGGGATCAACGATTCGCTGGCGCTCAAGGCGGGCGTGGTCGGAGTGGCGA
TGGGCGCGGGCGGCGCAGACATCGCGCTGGCGTCCGCCGACATTGTGCTGATTGGCAGTGACCTGCGTCGGCTCGGCACC
TGCGTGCGCCTGAGTCGTCAGTGCCGACGGACTTTACAAGTTAACGTAATCATCGGTCTGGGCTGGACGCTGGCCATCGT
GGTGTTCGCTGCTTTCGGCTGGCTCGGTGCGGCGGGGGCGATGATCGCCGCATTGCTGCACAACCTGAGCACGCTGTTGG
TGCTGGGCAATGCCGGACGCCTGCTGCGTTTTCAGGAACCACTGCTGAAGCTGAAAGTGTCGGACTGA

Upstream 100 bases:

>100_bases
TGTACCGTGAGCGGATGCCGAAGATTCTCGGGCAGGCCGGTTCGGTCACCACGGTCGATCCGAAAGACGATTCCCGCCTG
ATCATTCAGGGAGCCAGTAA

Downstream 100 bases:

>100_bases
TCAATTTTCGAACTGTGCGCCGCTCTCGCAGTCATTTGAGAAGGCGCACTGAACCAGGGATGACAGCGCCATTACAGCCA
CTGCGGCTGATAGTCGGCGA

Product: heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MTATTSAPSLLSSAEQRRAARQLTLAMLALGLLGLGLIWRWLMPEQSGVSQLLLGFASLLVAVPVMRSAWFSLRYPSLHG
ITDQLIALAMIGAWATGDLLTAALLPIIMIFGHVLEERSVIGSQEAIHALGQLTRSHARKVQADGSIIEVDNGTLKAGDK
VEVRAGDRVPADGRVLSGQASLDTASITGESVPVEAGVGMAVFGGAINLDGLLRIEVTRTGDESTLGKVIALMQNAERSK
PPITRLLERYAGSYMVLVLLLAAVTWFITNDAQAMLAVLVAACPCALVLSAPATAIAGVAVAARHGILIRSSAFLEELAD
LTSLVVDKTGTLTYGTLRLQSINSPRADHGSVMALAASLGAASSHPVSRALAGLVSAEEVLVLTDIHERQGLGVVAKTAQ
GEAALGRPELFAQLGIPTTAIPEHDGPIAGLALNGEFLAWLLLADTVKPEARFALSELRDLGLGRQLLLTGDRQSVAQTL
AKDVGLHEVEAQALPEDKLNRVLKEIDNGFRPMVVGDGINDSLALKAGVVGVAMGAGGADIALASADIVLIGSDLRRLGT
CVRLSRQCRRTLQVNVIIGLGWTLAIVVFAAFGWLGAAGAMIAALLHNLSTLLVLGNAGRLLRFQEPLLKLKVSD

Sequences:

>Translated_635_residues
MTATTSAPSLLSSAEQRRAARQLTLAMLALGLLGLGLIWRWLMPEQSGVSQLLLGFASLLVAVPVMRSAWFSLRYPSLHG
ITDQLIALAMIGAWATGDLLTAALLPIIMIFGHVLEERSVIGSQEAIHALGQLTRSHARKVQADGSIIEVDNGTLKAGDK
VEVRAGDRVPADGRVLSGQASLDTASITGESVPVEAGVGMAVFGGAINLDGLLRIEVTRTGDESTLGKVIALMQNAERSK
PPITRLLERYAGSYMVLVLLLAAVTWFITNDAQAMLAVLVAACPCALVLSAPATAIAGVAVAARHGILIRSSAFLEELAD
LTSLVVDKTGTLTYGTLRLQSINSPRADHGSVMALAASLGAASSHPVSRALAGLVSAEEVLVLTDIHERQGLGVVAKTAQ
GEAALGRPELFAQLGIPTTAIPEHDGPIAGLALNGEFLAWLLLADTVKPEARFALSELRDLGLGRQLLLTGDRQSVAQTL
AKDVGLHEVEAQALPEDKLNRVLKEIDNGFRPMVVGDGINDSLALKAGVVGVAMGAGGADIALASADIVLIGSDLRRLGT
CVRLSRQCRRTLQVNVIIGLGWTLAIVVFAAFGWLGAAGAMIAALLHNLSTLLVLGNAGRLLRFQEPLLKLKVSD
>Mature_634_residues
TATTSAPSLLSSAEQRRAARQLTLAMLALGLLGLGLIWRWLMPEQSGVSQLLLGFASLLVAVPVMRSAWFSLRYPSLHGI
TDQLIALAMIGAWATGDLLTAALLPIIMIFGHVLEERSVIGSQEAIHALGQLTRSHARKVQADGSIIEVDNGTLKAGDKV
EVRAGDRVPADGRVLSGQASLDTASITGESVPVEAGVGMAVFGGAINLDGLLRIEVTRTGDESTLGKVIALMQNAERSKP
PITRLLERYAGSYMVLVLLLAAVTWFITNDAQAMLAVLVAACPCALVLSAPATAIAGVAVAARHGILIRSSAFLEELADL
TSLVVDKTGTLTYGTLRLQSINSPRADHGSVMALAASLGAASSHPVSRALAGLVSAEEVLVLTDIHERQGLGVVAKTAQG
EAALGRPELFAQLGIPTTAIPEHDGPIAGLALNGEFLAWLLLADTVKPEARFALSELRDLGLGRQLLLTGDRQSVAQTLA
KDVGLHEVEAQALPEDKLNRVLKEIDNGFRPMVVGDGINDSLALKAGVVGVAMGAGGADIALASADIVLIGSDLRRLGTC
VRLSRQCRRTLQVNVIIGLGWTLAIVVFAAFGWLGAAGAMIAALLHNLSTLLVLGNAGRLLRFQEPLLKLKVSD

Specific function: Probably involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=577, Percent_Identity=28.9428076256499, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI55743073, Length=488, Percent_Identity=30.1229508196721, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI115529486, Length=438, Percent_Identity=27.3972602739726, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI51944966, Length=279, Percent_Identity=27.9569892473118, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI22748667, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4502271, Length=212, Percent_Identity=26.8867924528302, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI21361181, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI237681111, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI237681109, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI83700225, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762687, Length=276, Percent_Identity=26.4492753623188, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI48762689, Length=276, Percent_Identity=26.4492753623188, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI48762691, Length=276, Percent_Identity=26.4492753623188, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI48762685, Length=276, Percent_Identity=26.4492753623188, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789879, Length=593, Percent_Identity=33.0522765598651, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1786691, Length=624, Percent_Identity=31.25, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1786914, Length=544, Percent_Identity=27.2058823529412, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17556548, Length=323, Percent_Identity=30.030959752322, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17559224, Length=286, Percent_Identity=24.4755244755245, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557770, Length=302, Percent_Identity=25.1655629139073, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320475, Length=629, Percent_Identity=26.8680445151033, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319772, Length=554, Percent_Identity=25.4512635379061, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6321430, Length=524, Percent_Identity=24.4274809160305, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325221, Length=534, Percent_Identity=24.1573033707865, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321271, Length=259, Percent_Identity=27.4131274131274, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221329854, Length=377, Percent_Identity=29.1777188328912, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281366676, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 66455; Mature: 66324

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTSAPSLLSSAEQRRAARQLTLAMLALGLLGLGLIWRWLMPEQSGVSQLLLGFASLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VAVPVMRSAWFSLRYPSLHGITDQLIALAMIGAWATGDLLTAALLPIIMIFGHVLEERSV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGSQEAIHALGQLTRSHARKVQADGSIIEVDNGTLKAGDKVEVRAGDRVPADGRVLSGQA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCEEEEECCCCCCCCCEEEECCC
SLDTASITGESVPVEAGVGMAVFGGAINLDGLLRIEVTRTGDESTLGKVIALMQNAERSK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC
PPITRLLERYAGSYMVLVLLLAAVTWFITNDAQAMLAVLVAACPCALVLSAPATAIAGVA
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VAARHGILIRSSAFLEELADLTSLVVDKTGTLTYGTLRLQSINSPRADHGSVMALAASLG
HHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHC
AASSHPVSRALAGLVSAEEVLVLTDIHERQGLGVVAKTAQGEAALGRPELFAQLGIPTTA
CCCCCCHHHHHHHHHCCCCEEEEEECHHHCCCCEEEECCCCCCCCCCHHHHHHCCCCCCC
IPEHDGPIAGLALNGEFLAWLLLADTVKPEARFALSELRDLGLGRQLLLTGDRQSVAQTL
CCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
AKDVGLHEVEAQALPEDKLNRVLKEIDNGFRPMVVGDGINDSLALKAGVVGVAMGAGGAD
HHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCEEEEECCCCCC
IALASADIVLIGSDLRRLGTCVRLSRQCRRTLQVNVIIGLGWTLAIVVFAAFGWLGAAGA
EEEECCCEEEECHHHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHH
MIAALLHNLSTLLVLGNAGRLLRFQEPLLKLKVSD
HHHHHHHHHHEEEEECCCCCEEEECCCCEEEEECC
>Mature Secondary Structure 
TATTSAPSLLSSAEQRRAARQLTLAMLALGLLGLGLIWRWLMPEQSGVSQLLLGFASLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VAVPVMRSAWFSLRYPSLHGITDQLIALAMIGAWATGDLLTAALLPIIMIFGHVLEERSV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGSQEAIHALGQLTRSHARKVQADGSIIEVDNGTLKAGDKVEVRAGDRVPADGRVLSGQA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCEEEEECCCCCCCCCEEEECCC
SLDTASITGESVPVEAGVGMAVFGGAINLDGLLRIEVTRTGDESTLGKVIALMQNAERSK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC
PPITRLLERYAGSYMVLVLLLAAVTWFITNDAQAMLAVLVAACPCALVLSAPATAIAGVA
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VAARHGILIRSSAFLEELADLTSLVVDKTGTLTYGTLRLQSINSPRADHGSVMALAASLG
HHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHC
AASSHPVSRALAGLVSAEEVLVLTDIHERQGLGVVAKTAQGEAALGRPELFAQLGIPTTA
CCCCCCHHHHHHHHHCCCCEEEEEECHHHCCCCEEEECCCCCCCCCCHHHHHHCCCCCCC
IPEHDGPIAGLALNGEFLAWLLLADTVKPEARFALSELRDLGLGRQLLLTGDRQSVAQTL
CCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
AKDVGLHEVEAQALPEDKLNRVLKEIDNGFRPMVVGDGINDSLALKAGVVGVAMGAGGAD
HHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCEEEEECCCCCC
IALASADIVLIGSDLRRLGTCVRLSRQCRRTLQVNVIIGLGWTLAIVVFAAFGWLGAAGA
EEEECCCEEEECHHHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHH
MIAALLHNLSTLLVLGNAGRLLRFQEPLLKLKVSD
HHHHHHHHHHEEEEECCCCCEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]