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The map label for this gene is sstT

Identifier: 77459931

GI number: 77459931

Start: 4196252

End: 4197493

Strand: Direct

Name: sstT

Synonym: Pfl01_3709

Alternate gene names: 77459931

Gene position: 4196252-4197493 (Clockwise)

Preceding gene: 77459929

Following gene: 77459933

Centisome position: 65.18

GC content: 62.64

Gene sequence:

>1242_bases
ATGCCGTTCATGACCGCTTCATCCCCTTCTCTATTGCAACGCCTCAAAAGCCTCAGCCTGGTCACCCAGATCCTTATCGG
CCTGATTGCCGGCATCGCCCTCGCGCTGTTCGCGCCGGAAGCGGCCAAAGGCACGGCCTTCATCGGCAAGGTGTTCGTCT
CGGCACTGAAAGCCGTGGCGCCGATCCTGGTGTTCGTGCTGGTCATGGCCTCGATCGCCAACCACAAGCACGGTCAGGAA
ACCCACATCCGGCCGATTCTGTTCCTGTATCTGCTGGGCACCTTCGCCGCCGCCGTGGTCGCGGTGATTGCCAGCATGAT
GTTCCCGTCGCATCTGGTGCTGTCCACCGACAACATCGCCGTAAGCGCGCCGGGCGGCATCAGTGAAGTGCTGCAAAGCC
TGTTGCTGAGCGTGGTCGACAACCCGGTGAGCGCACTGATGAACGCCAACTTCATCGGCATTCTGGCCTGGGCCATCGGC
ATGGGCGTGGCGATCCGGCACGCGGGCGACACTACCCGCGAAGTGCTGGGTGATCTGTCCAACGGCGTGACAGTGATTGT
CCGGGTCGTGATCCGTTTTGCGCCGCTGGGTATTTTCGGCCTGGTGGCATCGACCCTGGCCACCTCCGGGTTTGGTGCAT
TGATCGGTTATGCGCATCTGCTGGCAGTGCTGCTCGGCTGCATGCTGTTCGTGGCGCTGGTGATGAATCCGCTGATCGTG
TTCTGGAAACTGCGTCGCAACCCTTATCCACTGACACTTCAGTGCCTGCGCGAAAGCGGCATCACCGCGTTCTTCACCCG
CAGCTCGGCGGCGAACATTCCGGTCAACCTGGAATTGAGCAAGCGTCTGGGCCTGCATGAAGACACCTACTCGGTATCGA
TCCCGCTCGGCGCCACCATCAACATGGCGGGTGCGGCGATCACCATCACCGTACTGAGCCTCGCGGCCGTGCACACCCTG
GGCATTGCGGTGGACATCCCGACCGCGATTTTGCTCAGCGTCGTCGCGGCGATCTGTGCCTGCGGTGCTTCGGGTGTGGC
CGGTGGCTCGCTGCTGCTGATTCCGCTGGCCTGCAGCCTGTTTGGCATCCCGAGCGAAATCGCCATGCAGGTGGTGGCAG
TCGGCTTCATCATCGGCGTGCTGCAGGATTCGGCCGAGACGGCGCTGAACTCCTCCACCGACGTGCTGTTCACCGCCGCC
GCGTGCCTGGGCGAAGAGCAGAAAGCCCAGCGTCCGGCGTAA

Upstream 100 bases:

>100_bases
ACGGCGTGGTTGGCGCGTCAGTCCTTTCGGTTCGTGTCTGTGGCCTGCCCCCGATTCAACGCCCGGATTGCGCAACCTTG
CACCCTATAAAAAAACAGAG

Downstream 100 bases:

>100_bases
AAGCCCGGCGCAACAAAAAGCCCGCCAAGGCGCAAACCTTGGCGGGCTTTTTGTTGCAGAACGTTTTAGAACGCGCCCAT
GTAATCGCGCTTGCCCACTT

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MPFMTASSPSLLQRLKSLSLVTQILIGLIAGIALALFAPEAAKGTAFIGKVFVSALKAVAPILVFVLVMASIANHKHGQE
THIRPILFLYLLGTFAAAVVAVIASMMFPSHLVLSTDNIAVSAPGGISEVLQSLLLSVVDNPVSALMNANFIGILAWAIG
MGVAIRHAGDTTREVLGDLSNGVTVIVRVVIRFAPLGIFGLVASTLATSGFGALIGYAHLLAVLLGCMLFVALVMNPLIV
FWKLRRNPYPLTLQCLRESGITAFFTRSSAANIPVNLELSKRLGLHEDTYSVSIPLGATINMAGAAITITVLSLAAVHTL
GIAVDIPTAILLSVVAAICACGASGVAGGSLLLIPLACSLFGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAA
ACLGEEQKAQRPA

Sequences:

>Translated_413_residues
MPFMTASSPSLLQRLKSLSLVTQILIGLIAGIALALFAPEAAKGTAFIGKVFVSALKAVAPILVFVLVMASIANHKHGQE
THIRPILFLYLLGTFAAAVVAVIASMMFPSHLVLSTDNIAVSAPGGISEVLQSLLLSVVDNPVSALMNANFIGILAWAIG
MGVAIRHAGDTTREVLGDLSNGVTVIVRVVIRFAPLGIFGLVASTLATSGFGALIGYAHLLAVLLGCMLFVALVMNPLIV
FWKLRRNPYPLTLQCLRESGITAFFTRSSAANIPVNLELSKRLGLHEDTYSVSIPLGATINMAGAAITITVLSLAAVHTL
GIAVDIPTAILLSVVAAICACGASGVAGGSLLLIPLACSLFGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAA
ACLGEEQKAQRPA
>Mature_412_residues
PFMTASSPSLLQRLKSLSLVTQILIGLIAGIALALFAPEAAKGTAFIGKVFVSALKAVAPILVFVLVMASIANHKHGQET
HIRPILFLYLLGTFAAAVVAVIASMMFPSHLVLSTDNIAVSAPGGISEVLQSLLLSVVDNPVSALMNANFIGILAWAIGM
GVAIRHAGDTTREVLGDLSNGVTVIVRVVIRFAPLGIFGLVASTLATSGFGALIGYAHLLAVLLGCMLFVALVMNPLIVF
WKLRRNPYPLTLQCLRESGITAFFTRSSAANIPVNLELSKRLGLHEDTYSVSIPLGATINMAGAAITITVLSLAAVHTLG
IAVDIPTAILLSVVAAICACGASGVAGGSLLLIPLACSLFGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAA
CLGEEQKAQRPA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI4827012, Length=263, Percent_Identity=26.9961977186312, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI169790839, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=28.3464566929134, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI223468566, Length=254, Percent_Identity=28.3464566929134, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21314632, Length=313, Percent_Identity=25.5591054313099, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5032093, Length=254, Percent_Identity=28.3464566929134, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI40254478, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI66773030, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789473, Length=404, Percent_Identity=68.8118811881188, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1789947, Length=358, Percent_Identity=24.0223463687151, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790514, Length=424, Percent_Identity=24.0566037735849, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537407, Length=258, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=263, Percent_Identity=25.0950570342205, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=249, Percent_Identity=25.3012048192771, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583025, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17137668, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583023, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_PSEPF (Q3K9V7)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_349438.1
- ProteinModelPortal:   Q3K9V7
- SMR:   Q3K9V7
- STRING:   Q3K9V7
- GeneID:   3714601
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_3709
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   THIRPIL
- ProtClustDB:   PRK13628
- BioCyc:   PFLU205922:PFL_3709-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 42713; Mature: 42582

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1153db90)-; HASH(0x12f02a88)-; HASH(0x126568fc)-; HASH(0x1332d6b4)-; HASH(0x136a69b0)-; HASH(0x136421b8)-; HASH(0x136bedf4)-; HASH(0x132bef2c)-; HASH(0x136cb528)-; HASH(0x12f192ac)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFMTASSPSLLQRLKSLSLVTQILIGLIAGIALALFAPEAAKGTAFIGKVFVSALKAVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
PILVFVLVMASIANHKHGQETHIRPILFLYLLGTFAAAVVAVIASMMFPSHLVLSTDNIA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEE
VSAPGGISEVLQSLLLSVVDNPVSALMNANFIGILAWAIGMGVAIRHAGDTTREVLGDLS
EECCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHC
NGVTVIVRVVIRFAPLGIFGLVASTLATSGFGALIGYAHLLAVLLGCMLFVALVMNPLIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWKLRRNPYPLTLQCLRESGITAFFTRSSAANIPVNLELSKRLGLHEDTYSVSIPLGATI
HHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHCCCCCCCEEEEECCCCEE
NMAGAAITITVLSLAAVHTLGIAVDIPTAILLSVVAAICACGASGVAGGSLLLIPLACSL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACLGEEQKAQRPA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCCH
>Mature Secondary Structure 
PFMTASSPSLLQRLKSLSLVTQILIGLIAGIALALFAPEAAKGTAFIGKVFVSALKAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
PILVFVLVMASIANHKHGQETHIRPILFLYLLGTFAAAVVAVIASMMFPSHLVLSTDNIA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEE
VSAPGGISEVLQSLLLSVVDNPVSALMNANFIGILAWAIGMGVAIRHAGDTTREVLGDLS
EECCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHC
NGVTVIVRVVIRFAPLGIFGLVASTLATSGFGALIGYAHLLAVLLGCMLFVALVMNPLIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWKLRRNPYPLTLQCLRESGITAFFTRSSAANIPVNLELSKRLGLHEDTYSVSIPLGATI
HHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHCCCCCCCEEEEECCCCEE
NMAGAAITITVLSLAAVHTLGIAVDIPTAILLSVVAAICACGASGVAGGSLLLIPLACSL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACLGEEQKAQRPA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA