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The map label for this gene is nhaR [H]

Identifier: 77459929

GI number: 77459929

Start: 4193866

End: 4194765

Strand: Direct

Name: nhaR [H]

Synonym: Pfl01_3707

Alternate gene names: 77459929

Gene position: 4193866-4194765 (Clockwise)

Preceding gene: 77459926

Following gene: 77459931

Centisome position: 65.14

GC content: 61.78

Gene sequence:

>900_bases
ATGCTCAATTACCGACAACTGCACTATTTCTGGGTGGTGGCCAAGACCGGCAGCATCGTGCGCGCCTGCGAGCAACTGAA
CCTGACGCCGCAGACCATCAGCGGGCAGATTTCCCTGCTCGAACAGACCTACGGCATCGAGCTGTTTCAACGAGTCGGCC
GGCAATTAGAGCTCACCGAGGCCGGGCGCCAGGCCCTGCCCTACGCCGAGCAGATGTTCCAGCTCGGCGGCGAACTGGAG
TTGATGCTGCGCGCCCAGCCCAATGAACAGCAGATCCTGTTCCGGGTCGGCGTGGCGGACGTGGTGCCCAAATCCATCGT
CTATCGCCTGATCGCGCCGACCATGGAATTGAGCGAGCCACTACGCATCACCTGCCGCGAAGACAAACTCGAGAGGTTAC
TGGCGGACCTGGCAATCCAGCGCCTGGACCTGGTGATCTCCGACAGCCCGATGCCCTCGCACCTGGACATCAAGGGCTAC
AGCCAGAAACTCGGGGAATGCGGGATCAGTTTCTTTGCCACCGCAGAACTGGCCGCGCAATACGGTCAGGATTTCCCGCG
CAGCCTCCACGGTGCGCCGCTGTTGATCCCCGGCGCGGAAACCGTGGTGCGCAGTCGCTTACAGCGCTGGTTCGCCGAGC
AGCAGATTCAGCCGAGGATTGTCGGGGAGTTCGATGACAGCGCCCTGATGCAGGCGTTCGGCCAGTCCGGCAGCGGGATT
TTCATCGGCCCGAGCGTGATTGCCGATGAGGTGAAGCGCCAGTACGGCGTCGAGTTGATCGGCCAGACCGATGCGGTGAG
CGAGTCGTTCTACGCGATCTCGGTGGAGCGCAAGGTCAAGCACCCCGGTATCAAAGCGATTACCGAAGGTGCCCGACGCG
AGCTGTTTACAGCCTTTTAA

Upstream 100 bases:

>100_bases
GATGGCTGGGCATTCTAGGGAGACAAACACTTCAGGAAAATTCGTATTTTTAGCGGCTATACTTCGATTTATACGAACTG
TATTTGACGGACCGAACCCC

Downstream 100 bases:

>100_bases
GCCGGCGCACAGGCGTCGCGCGGCTTGAGCACCATCAGCACCATGGCGAGGAAAATCGACAGCAGAATGAACCCGGCGGC
GGCGAAGCCCACAAAGCCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTYGIELFQRVGRQLELTEAGRQALPYAEQMFQLGGELE
LMLRAQPNEQQILFRVGVADVVPKSIVYRLIAPTMELSEPLRITCREDKLERLLADLAIQRLDLVISDSPMPSHLDIKGY
SQKLGECGISFFATAELAAQYGQDFPRSLHGAPLLIPGAETVVRSRLQRWFAEQQIQPRIVGEFDDSALMQAFGQSGSGI
FIGPSVIADEVKRQYGVELIGQTDAVSESFYAISVERKVKHPGIKAITEGARRELFTAF

Sequences:

>Translated_299_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTYGIELFQRVGRQLELTEAGRQALPYAEQMFQLGGELE
LMLRAQPNEQQILFRVGVADVVPKSIVYRLIAPTMELSEPLRITCREDKLERLLADLAIQRLDLVISDSPMPSHLDIKGY
SQKLGECGISFFATAELAAQYGQDFPRSLHGAPLLIPGAETVVRSRLQRWFAEQQIQPRIVGEFDDSALMQAFGQSGSGI
FIGPSVIADEVKRQYGVELIGQTDAVSESFYAISVERKVKHPGIKAITEGARRELFTAF
>Mature_299_residues
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTYGIELFQRVGRQLELTEAGRQALPYAEQMFQLGGELE
LMLRAQPNEQQILFRVGVADVVPKSIVYRLIAPTMELSEPLRITCREDKLERLLADLAIQRLDLVISDSPMPSHLDIKGY
SQKLGECGISFFATAELAAQYGQDFPRSLHGAPLLIPGAETVVRSRLQRWFAEQQIQPRIVGEFDDSALMQAFGQSGSGI
FIGPSVIADEVKRQYGVELIGQTDAVSESFYAISVERKVKHPGIKAITEGARRELFTAF

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=39.1891891891892, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33446; Mature: 33446

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTYGIELFQRVGRQLELTE
CCCCEEEEEEEEEECCCHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEEHHH
AGRQALPYAEQMFQLGGELELMLRAQPNEQQILFRVGVADVVPKSIVYRLIAPTMELSEP
HHHHCCCHHHHHHHCCCCEEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHCHHHCCCC
LRITCREDKLERLLADLAIQRLDLVISDSPMPSHLDIKGYSQKLGECGISFFATAELAAQ
EEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
YGQDFPRSLHGAPLLIPGAETVVRSRLQRWFAEQQIQPRIVGEFDDSALMQAFGQSGSGI
HCCCCCHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCCCCEE
FIGPSVIADEVKRQYGVELIGQTDAVSESFYAISVERKVKHPGIKAITEGARRELFTAF
EECHHHHHHHHHHHHCCEEECCCHHHCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTYGIELFQRVGRQLELTE
CCCCEEEEEEEEEECCCHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEEEHHH
AGRQALPYAEQMFQLGGELELMLRAQPNEQQILFRVGVADVVPKSIVYRLIAPTMELSEP
HHHHCCCHHHHHHHCCCCEEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHCHHHCCCC
LRITCREDKLERLLADLAIQRLDLVISDSPMPSHLDIKGYSQKLGECGISFFATAELAAQ
EEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
YGQDFPRSLHGAPLLIPGAETVVRSRLQRWFAEQQIQPRIVGEFDDSALMQAFGQSGSGI
HCCCCCHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCCCCEE
FIGPSVIADEVKRQYGVELIGQTDAVSESFYAISVERKVKHPGIKAITEGARRELFTAF
EECHHHHHHHHHHHHCCEEECCCHHHCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]