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The map label for this gene is pbpG [H]

Identifier: 77459922

GI number: 77459922

Start: 4190045

End: 4190983

Strand: Direct

Name: pbpG [H]

Synonym: Pfl01_3700

Alternate gene names: 77459922

Gene position: 4190045-4190983 (Clockwise)

Preceding gene: 77459921

Following gene: 77459926

Centisome position: 65.08

GC content: 59.11

Gene sequence:

>939_bases
GTGAATATTCGTCTGTCCATCCTGAGCCTGGTTTTTGCATTTTCAGGCACACTCCTCACGCCCACGGTCAACGCCGCCGA
AACCACCGCTGCCCCCCGAGACGCCTCGCAACTGAAGATTGCGTCCGGCAGCGCCCTGCTGATGGATCTGCAGACCAACA
AAGTCATCTATTCCAGCAACCCGGACGTGGTGGTGCCCATCGCCTCCGTGAGCAAATTGATGACCGGGTTGGTAGTGGTC
GAAGCGCATCAGAACATGGACGAATGGATTGACGTCGACATCAGTCACACCCCGGAAATGAAAGGCGTGTTTTCCCGCGT
CAAACTGCGAAGCGAACTGCCCCGCCGGGAGATGCTGCTGATTGCCCTGATGTCCTCGGAAAACCGCGCCGCCGCCAGCC
TGGCCCACCACTATCCGGGTGGTTACGCGGCATTCATCGCAGCGATGAACGCCAAGGCCAAGGCGCTGGGCATGACCAGC
ACGCACTTTGTCGAACCCACCGGTTTGTCGGAGCGCAATGTCTCCACTGCCCGCGACCTGAGCAAGTTGCTGGTGGCCGC
GCACAAACAGCCGCTGCTCATCGAGCTGACCACCACCAAGGAAAAGACCGTCTCGTTCCGCAAACCCAATTACACCCTGG
GTTTCCGTAACACCGATCACCTGGTCAACAAGGCCGACTGGGATATCCGCATCACCAAGACCGGTTTCACCAATCCTGCC
GGTCATTGCCTGGTGCTGGTGACCCGCATGGCCAACCGTCCCGTCGCCCTGGTAATTCTCGACGCGTTCGGCAAATACAC
TCACTTTGCCGATGCCAGCCGCATCCGCAGCTGGGTGGAAACCGGCAAGAGCGCCAACGTTCCAGCGGTGGCTCAGCAAT
ACAAAGCCGACAAGAACCTCAAGAGTCGCCAGAGCGGCGTAATCGAAGCCTCCAAGTAA

Upstream 100 bases:

>100_bases
AACCATCGACAGTTCTTCAACCATACTCCTACAATGCGTCGTTTTTACGACACAGCCCGTTACAAAGAACGGCATCTCCA
ACCTTCATGAGTTCGCCCGC

Downstream 100 bases:

>100_bases
ATCGCCCACCCATGAAAAAGCCCCGACTCGTCGGGGCTTTTTCGTTTATGCACTCAGTCGTTGGGCAACGGCATCTTGTC
GTCATCGGGAATGCCGTCAC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNIRLSILSLVFAFSGTLLTPTVNAAETTAAPRDASQLKIASGSALLMDLQTNKVIYSSNPDVVVPIASVSKLMTGLVVV
EAHQNMDEWIDVDISHTPEMKGVFSRVKLRSELPRREMLLIALMSSENRAAASLAHHYPGGYAAFIAAMNAKAKALGMTS
THFVEPTGLSERNVSTARDLSKLLVAAHKQPLLIELTTTKEKTVSFRKPNYTLGFRNTDHLVNKADWDIRITKTGFTNPA
GHCLVLVTRMANRPVALVILDAFGKYTHFADASRIRSWVETGKSANVPAVAQQYKADKNLKSRQSGVIEASK

Sequences:

>Translated_312_residues
MNIRLSILSLVFAFSGTLLTPTVNAAETTAAPRDASQLKIASGSALLMDLQTNKVIYSSNPDVVVPIASVSKLMTGLVVV
EAHQNMDEWIDVDISHTPEMKGVFSRVKLRSELPRREMLLIALMSSENRAAASLAHHYPGGYAAFIAAMNAKAKALGMTS
THFVEPTGLSERNVSTARDLSKLLVAAHKQPLLIELTTTKEKTVSFRKPNYTLGFRNTDHLVNKADWDIRITKTGFTNPA
GHCLVLVTRMANRPVALVILDAFGKYTHFADASRIRSWVETGKSANVPAVAQQYKADKNLKSRQSGVIEASK
>Mature_312_residues
MNIRLSILSLVFAFSGTLLTPTVNAAETTAAPRDASQLKIASGSALLMDLQTNKVIYSSNPDVVVPIASVSKLMTGLVVV
EAHQNMDEWIDVDISHTPEMKGVFSRVKLRSELPRREMLLIALMSSENRAAASLAHHYPGGYAAFIAAMNAKAKALGMTS
THFVEPTGLSERNVSTARDLSKLLVAAHKQPLLIELTTTKEKTVSFRKPNYTLGFRNTDHLVNKADWDIRITKTGFTNPA
GHCLVLVTRMANRPVALVILDAFGKYTHFADASRIRSWVETGKSANVPAVAQQYKADKNLKSRQSGVIEASK

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=259, Percent_Identity=67.5675675675676, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787062, Length=281, Percent_Identity=28.8256227758007, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786851, Length=225, Percent_Identity=28.4444444444444, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34044; Mature: 34044

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRLSILSLVFAFSGTLLTPTVNAAETTAAPRDASQLKIASGSALLMDLQTNKVIYSSN
CCEEHHHHHHHHHHCCEEECCCCCCHHCCCCCCCCCCEEEECCCEEEEEEECCEEEEECC
PDVVVPIASVSKLMTGLVVVEAHQNMDEWIDVDISHTPEMKGVFSRVKLRSELPRREMLL
CCEEEEHHHHHHHHHHEEEEEECCCCCHHEEECCCCCCHHHHHHHHHHHHHHCCHHHEEE
IALMSSENRAAASLAHHYPGGYAAFIAAMNAKAKALGMTSTHFVEPTGLSERNVSTARDL
EEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHEECCCCCEEECCCCCCCCCCHHHHHH
SKLLVAAHKQPLLIELTTTKEKTVSFRKPNYTLGFRNTDHLVNKADWDIRITKTGFTNPA
HHHHHHHCCCCEEEEEECCCCCEEEEECCCEEECCCCCHHHCCCCCCEEEEEECCCCCCC
GHCLVLVTRMANRPVALVILDAFGKYTHFADASRIRSWVETGKSANVPAVAQQYKADKNL
CHHEEEEEHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCH
KSRQSGVIEASK
HHHHCCCEECCC
>Mature Secondary Structure
MNIRLSILSLVFAFSGTLLTPTVNAAETTAAPRDASQLKIASGSALLMDLQTNKVIYSSN
CCEEHHHHHHHHHHCCEEECCCCCCHHCCCCCCCCCCEEEECCCEEEEEEECCEEEEECC
PDVVVPIASVSKLMTGLVVVEAHQNMDEWIDVDISHTPEMKGVFSRVKLRSELPRREMLL
CCEEEEHHHHHHHHHHEEEEEECCCCCHHEEECCCCCCHHHHHHHHHHHHHHCCHHHEEE
IALMSSENRAAASLAHHYPGGYAAFIAAMNAKAKALGMTSTHFVEPTGLSERNVSTARDL
EEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHEECCCCCEEECCCCCCCCCCHHHHHH
SKLLVAAHKQPLLIELTTTKEKTVSFRKPNYTLGFRNTDHLVNKADWDIRITKTGFTNPA
HHHHHHHCCCCEEEEEECCCCCEEEEECCCEEECCCCCHHHCCCCCCEEEEEECCCCCCC
GHCLVLVTRMANRPVALVILDAFGKYTHFADASRIRSWVETGKSANVPAVAQQYKADKNL
CHHEEEEEHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCH
KSRQSGVIEASK
HHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]