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The map label for this gene is marR [H]

Identifier: 77459867

GI number: 77459867

Start: 4122600

End: 4123082

Strand: Reverse

Name: marR [H]

Synonym: Pfl01_3645

Alternate gene names: 77459867

Gene position: 4123082-4122600 (Counterclockwise)

Preceding gene: 77459868

Following gene: 77459866

Centisome position: 64.04

GC content: 59.83

Gene sequence:

>483_bases
ATGAAGCATTTCACCCCAGACGAATTCCAGCATTGCCATCTCGGCCTGTTGCTCGGCCGTGCGGCCTTGCTCAAGGACAA
GATCATCGACACCCACATGGAACCCCACGGCATCACCGCCGCGCAGTTCAAGGTGTTGATCATCATGGCCCAGTTCGGCG
TCGACACCCCGGCCGAGCTGTGCCGGCACCTGTCGCTGGACAGCGGTTCGATGACTCGCATGCTCGATCGTCTGGAACAG
AAAGGCTTTCTGGTTCGCCAACGCAGCGAAGGCGATCGCCGTCAGGTGCAACTGAAACTCACCGAGCAGGGCCAGCAACT
GGCCGATCGCCTGCCGCACATCGGCGCCGACGCCATGAATGAGCTGGCCGGCGCCGTGACCCCGGACGAGTTGAAAACCC
TGGAATACATCCTCAAGAAAATTTTGCTGGCAGCCGGTGACCCCATCACCATCCAGCGGTTAGGTGAACACAATGAGCGG
TAA

Upstream 100 bases:

>100_bases
AACTAATTACAAAGCAACCTAACTATTACGTTGACATTCGCTGCCTAGGCAGTAACATCTCGACATACATTCACTGCCTA
GGCAGTTATTAGGTGAGCAC

Downstream 100 bases:

>100_bases
AATCTTGCGCAGCAGCCTGACACTGGTGCTGTCGGCGATGATCCTCGCCGGTTGCGCCAACTACAGTGGCCTCGATACCC
AGGGCGCCAGCCTCGATGCG

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKHFTPDEFQHCHLGLLLGRAALLKDKIIDTHMEPHGITAAQFKVLIIMAQFGVDTPAELCRHLSLDSGSMTRMLDRLEQ
KGFLVRQRSEGDRRQVQLKLTEQGQQLADRLPHIGADAMNELAGAVTPDELKTLEYILKKILLAAGDPITIQRLGEHNER

Sequences:

>Translated_160_residues
MKHFTPDEFQHCHLGLLLGRAALLKDKIIDTHMEPHGITAAQFKVLIIMAQFGVDTPAELCRHLSLDSGSMTRMLDRLEQ
KGFLVRQRSEGDRRQVQLKLTEQGQQLADRLPHIGADAMNELAGAVTPDELKTLEYILKKILLAAGDPITIQRLGEHNER
>Mature_160_residues
MKHFTPDEFQHCHLGLLLGRAALLKDKIIDTHMEPHGITAAQFKVLIIMAQFGVDTPAELCRHLSLDSGSMTRMLDRLEQ
KGFLVRQRSEGDRRQVQLKLTEQGQQLADRLPHIGADAMNELAGAVTPDELKTLEYILKKILLAAGDPITIQRLGEHNER

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=119, Percent_Identity=43.6974789915966, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17996; Mature: 17996

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFTPDEFQHCHLGLLLGRAALLKDKIIDTHMEPHGITAAQFKVLIIMAQFGVDTPAEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
CRHLSLDSGSMTRMLDRLEQKGFLVRQRSEGDRRQVQLKLTEQGQQLADRLPHIGADAMN
HHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
ELAGAVTPDELKTLEYILKKILLAAGDPITIQRLGEHNER
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC
>Mature Secondary Structure
MKHFTPDEFQHCHLGLLLGRAALLKDKIIDTHMEPHGITAAQFKVLIIMAQFGVDTPAEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
CRHLSLDSGSMTRMLDRLEQKGFLVRQRSEGDRRQVQLKLTEQGQQLADRLPHIGADAMN
HHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
ELAGAVTPDELKTLEYILKKILLAAGDPITIQRLGEHNER
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]