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The map label for this gene is qseB [H]

Identifier: 77459576

GI number: 77459576

Start: 3828134

End: 3828796

Strand: Direct

Name: qseB [H]

Synonym: Pfl01_3354

Alternate gene names: 77459576

Gene position: 3828134-3828796 (Clockwise)

Preceding gene: 77459575

Following gene: 77459577

Centisome position: 59.46

GC content: 63.2

Gene sequence:

>663_bases
GTGCGTTTATTACTGATCGAGGATGACGTGGCCCTCGGCGAGGGCATTCATCAGGCGCTGGGGCGCGAGGGCTACACGGT
CGACTGGCTCAAGGACGGCAGCAGCGCCCTGCACGCCCTGCTCAGCGAAAACTTTGATCTGGCGGTGCTCGATCTCGGCC
TGCCGCGCATGGATGGGCTCGAAGTCCTGCGTCGTCTGCGTGGCAGCGGTTCGAACCTGCCGGTGCTGATCCTCACCGCC
CGCGATGCCACCGAAGACCGCATCGCGGGGCTGGACGCCGGCGCCGACGACTACCTGATCAAGCCCTTCGACCTGGCCGA
ACTCAAGGCCCGCCTGCGCGCCCTTCTGCGACGCAGTGCCGGACGCGCGCAGATGCTGATCGAACATGCCGGCATCAGCC
TCAACCCCGGCACCCAGCAAGTCAGCTATCTGGGCCAACCGGTGGTACTCACGCCCAAGGAATATCAGTTGCTGCACGAA
CTGCTCTCGCCGCCGGGTCGGGTCATGACCCGTGACCACCTGACACAACTGCTTTACGGCTGGAACGAAGAAGCCGAAAG
CAACACTCTCGAAGTGCATATTCATCACCTGCGCAAGAAATTCTCCACCGACCTGATCCGCACCATTCGCGGCGTGGGTT
ATCTGGTGGAGGAGCGCCGATGA

Upstream 100 bases:

>100_bases
CTCCTCGCCCAGGCCGGGAAAGTGCCGATGCCGGACGCCGCAAAGAGATCGCCGCGTTGCTGGTGGACGTGAACAAGAAA
CTCGACTGACAGGAGTCCGT

Downstream 100 bases:

>100_bases
CCTCGATCCGGCGCCGCACCCTGACCCTGATCATCGGCCTGATGCTCGCCGGTCTGACCGTGCTCAGCCTGTTCAATCTG
CACGACAGCAACCACGAAAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRLLLIEDDVALGEGIHQALGREGYTVDWLKDGSSALHALLSENFDLAVLDLGLPRMDGLEVLRRLRGSGSNLPVLILTA
RDATEDRIAGLDAGADDYLIKPFDLAELKARLRALLRRSAGRAQMLIEHAGISLNPGTQQVSYLGQPVVLTPKEYQLLHE
LLSPPGRVMTRDHLTQLLYGWNEEAESNTLEVHIHHLRKKFSTDLIRTIRGVGYLVEERR

Sequences:

>Translated_220_residues
MRLLLIEDDVALGEGIHQALGREGYTVDWLKDGSSALHALLSENFDLAVLDLGLPRMDGLEVLRRLRGSGSNLPVLILTA
RDATEDRIAGLDAGADDYLIKPFDLAELKARLRALLRRSAGRAQMLIEHAGISLNPGTQQVSYLGQPVVLTPKEYQLLHE
LLSPPGRVMTRDHLTQLLYGWNEEAESNTLEVHIHHLRKKFSTDLIRTIRGVGYLVEERR
>Mature_220_residues
MRLLLIEDDVALGEGIHQALGREGYTVDWLKDGSSALHALLSENFDLAVLDLGLPRMDGLEVLRRLRGSGSNLPVLILTA
RDATEDRIAGLDAGADDYLIKPFDLAELKARLRALLRRSAGRAQMLIEHAGISLNPGTQQVSYLGQPVVLTPKEYQLLHE
LLSPPGRVMTRDHLTQLLYGWNEEAESNTLEVHIHHLRKKFSTDLIRTIRGVGYLVEERR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=48.4018264840183, Blast_Score=220, Evalue=7e-59,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=47.6851851851852, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=40.8256880733945, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.8888888888889, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=37.219730941704, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=35.5555555555556, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=34.9557522123894, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=217, Percent_Identity=36.8663594470046, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=36.986301369863, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=33.6363636363636, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.4035087719298, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.3964757709251, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=28.2608695652174, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=92, Percent_Identity=41.304347826087, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=28.0193236714976, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=118, Percent_Identity=33.0508474576271, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI145693157, Length=112, Percent_Identity=32.1428571428571, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=31.9327731092437, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24585; Mature: 24585

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLIEDDVALGEGIHQALGREGYTVDWLKDGSSALHALLSENFDLAVLDLGLPRMDGL
CEEEEEECCHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHH
EVLRRLRGSGSNLPVLILTARDATEDRIAGLDAGADDYLIKPFDLAELKARLRALLRRSA
HHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
GRAQMLIEHAGISLNPGTQQVSYLGQPVVLTPKEYQLLHELLSPPGRVMTRDHLTQLLYG
CHHHHHHHHCCCEECCCHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHC
WNEEAESNTLEVHIHHLRKKFSTDLIRTIRGVGYLVEERR
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLLLIEDDVALGEGIHQALGREGYTVDWLKDGSSALHALLSENFDLAVLDLGLPRMDGL
CEEEEEECCHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHH
EVLRRLRGSGSNLPVLILTARDATEDRIAGLDAGADDYLIKPFDLAELKARLRALLRRSA
HHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
GRAQMLIEHAGISLNPGTQQVSYLGQPVVLTPKEYQLLHELLSPPGRVMTRDHLTQLLYG
CHHHHHHHHCCCEECCCHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHC
WNEEAESNTLEVHIHHLRKKFSTDLIRTIRGVGYLVEERR
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]