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The map label for this gene is yciK [C]

Identifier: 77459008

GI number: 77459008

Start: 3208616

End: 3209599

Strand: Direct

Name: yciK [C]

Synonym: Pfl01_2783

Alternate gene names: 77459008

Gene position: 3208616-3209599 (Clockwise)

Preceding gene: 77459002

Following gene: 77459009

Centisome position: 49.84

GC content: 64.63

Gene sequence:

>984_bases
ATGCTGTTCGCCATTTCCGCGCTGGCCAGCACACTGGCTGCGCAAGCCACTTCCCGAACAGAGCCGAAGCCGGACTGGTC
AACCCAGGACATGCCCAGCCAGAATGGCCGCATCGTGCTGGTGACCGGAGGGACCAGCGGCATGGGCTATGAAGACGCGC
TGGCCCTGACGCGAGCCGGTGCCGAGGTGATCATCGCCGCACGGAACGCCGAGCGCGGCCGCGAAGCGATCGCAAACATC
AGGCAAGCCGTGCCCGAGGCGCGCGTGCAATTCGAAACGCTGGATCTTGCCAATCTGCAATCCGTGCGCGACCTCGCCAA
CCGCTTGCAAGGGCGTCTGCCAAGGCTCGACGTGCTCATCAACAACGCCGCCATCATGTCGCCGCCTGTTCGAGGCGTTT
CGGCCGACGGCTACGAGATGCAGCTGGCGACCAACTACCTGGGGCATTTCGCCTTGACCGGCCTGCTGATGCCTCTGCTA
CGCAAAAGCGACGATGGTCGGGTAGTCAGTCTGTCGAGCATCGCCGCAGGGCGCGCCGTCCTGAACTTCGATGACCTGCA
GGCTGAGCGCGCTTACGACCCGTTCACTACCTACAGCCAATCGAAACTGGCCGTACTCAAGTGGAGTATTGAGCTGCAGC
AACGCAGCGATGCCGCCGGTTGGGGCATACGCAGCATCGCCGCTCACCCCGGCGTTGCCGTGACCGAGCTGATCGCCCGA
GGGCCTGGCCTGGACAGTGAATTCGGCAAACAATGGGCTGTAGAGCGGGACATGTACCATTCCGCAGCGCAGGGCGCACT
GCCCACACTGTATGCGGCGACGGCGCCGGAGGCCGTCGGCGGAGCCTACTACGGGCCCACCGGTGATAACGAGAAGCGCG
GGCCGCTGGGCTTCGCCAAGATGCCTCCGGCCGCTGCCGATCGCTCGAATTCCGACGCGCTGTGGCAACTTTCCGAGCGT
CTGACCGGCGTGACCTACCGTTGA

Upstream 100 bases:

>100_bases
CAAACCGGGAACCTACAACGCGAGTGAGAATTCCCCGATGGTTCATTCACCCGTTACGCCGAGCATTACCGCAACCCAAC
GCATCCTCAAGGCCGTCCGG

Downstream 100 bases:

>100_bases
CCAACCCGGCACGGGCAAGCCGCGTGCCATTGCCTCGACACTCCTACAGGAGCGCAACATGGATATGTCCCTTCTCGCCC
AACGCACGAGCGCCATCATC

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLFAISALASTLAAQATSRTEPKPDWSTQDMPSQNGRIVLVTGGTSGMGYEDALALTRAGAEVIIAARNAERGREAIANI
RQAVPEARVQFETLDLANLQSVRDLANRLQGRLPRLDVLINNAAIMSPPVRGVSADGYEMQLATNYLGHFALTGLLMPLL
RKSDDGRVVSLSSIAAGRAVLNFDDLQAERAYDPFTTYSQSKLAVLKWSIELQQRSDAAGWGIRSIAAHPGVAVTELIAR
GPGLDSEFGKQWAVERDMYHSAAQGALPTLYAATAPEAVGGAYYGPTGDNEKRGPLGFAKMPPAAADRSNSDALWQLSER
LTGVTYR

Sequences:

>Translated_327_residues
MLFAISALASTLAAQATSRTEPKPDWSTQDMPSQNGRIVLVTGGTSGMGYEDALALTRAGAEVIIAARNAERGREAIANI
RQAVPEARVQFETLDLANLQSVRDLANRLQGRLPRLDVLINNAAIMSPPVRGVSADGYEMQLATNYLGHFALTGLLMPLL
RKSDDGRVVSLSSIAAGRAVLNFDDLQAERAYDPFTTYSQSKLAVLKWSIELQQRSDAAGWGIRSIAAHPGVAVTELIAR
GPGLDSEFGKQWAVERDMYHSAAQGALPTLYAATAPEAVGGAYYGPTGDNEKRGPLGFAKMPPAAADRSNSDALWQLSER
LTGVTYR
>Mature_327_residues
MLFAISALASTLAAQATSRTEPKPDWSTQDMPSQNGRIVLVTGGTSGMGYEDALALTRAGAEVIIAARNAERGREAIANI
RQAVPEARVQFETLDLANLQSVRDLANRLQGRLPRLDVLINNAAIMSPPVRGVSADGYEMQLATNYLGHFALTGLLMPLL
RKSDDGRVVSLSSIAAGRAVLNFDDLQAERAYDPFTTYSQSKLAVLKWSIELQQRSDAAGWGIRSIAAHPGVAVTELIAR
GPGLDSEFGKQWAVERDMYHSAAQGALPTLYAATAPEAVGGAYYGPTGDNEKRGPLGFAKMPPAAADRSNSDALWQLSER
LTGVTYR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=300, Percent_Identity=37.3333333333333, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI193804850, Length=303, Percent_Identity=33.993399339934, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI10190746, Length=309, Percent_Identity=34.9514563106796, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI186928839, Length=293, Percent_Identity=33.7883959044369, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7706523, Length=297, Percent_Identity=34.6801346801347, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI166795268, Length=261, Percent_Identity=33.7164750957854, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI146231950, Length=301, Percent_Identity=35.2159468438538, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI19923931, Length=265, Percent_Identity=36.6037735849057, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI13375997, Length=189, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4502601, Length=163, Percent_Identity=34.3558282208589, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4502599, Length=149, Percent_Identity=34.2281879194631, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=249, Percent_Identity=28.1124497991968, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4504503, Length=215, Percent_Identity=28.8372093023256, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787526, Length=148, Percent_Identity=35.8108108108108, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532805, Length=303, Percent_Identity=30.03300330033, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71992402, Length=308, Percent_Identity=29.2207792207792, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17532791, Length=298, Percent_Identity=29.8657718120805, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17558006, Length=300, Percent_Identity=29.3333333333333, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193207620, Length=300, Percent_Identity=29.3333333333333, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17505416, Length=215, Percent_Identity=33.953488372093, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17535059, Length=299, Percent_Identity=29.7658862876254, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72001364, Length=255, Percent_Identity=32.5490196078431, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565532, Length=209, Percent_Identity=29.1866028708134, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533172, Length=306, Percent_Identity=25.8169934640523, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533174, Length=295, Percent_Identity=25.7627118644068, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=215, Percent_Identity=31.6279069767442, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=211, Percent_Identity=31.7535545023697, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=27.8481012658228, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=214, Percent_Identity=28.0373831775701, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=297, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323882, Length=206, Percent_Identity=28.6407766990291, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324148, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573296, Length=301, Percent_Identity=37.2093023255814, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24586328, Length=295, Percent_Identity=34.9152542372881, Blast_Score=148, Evalue=4e-36,
Organism=Drosophila melanogaster, GI22024069, Length=306, Percent_Identity=33.0065359477124, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI19921754, Length=295, Percent_Identity=33.2203389830508, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI45554248, Length=291, Percent_Identity=35.0515463917526, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24640117, Length=291, Percent_Identity=35.0515463917526, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161076371, Length=259, Percent_Identity=35.1351351351351, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656154, Length=301, Percent_Identity=30.2325581395349, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI19922628, Length=301, Percent_Identity=30.2325581395349, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI20129347, Length=297, Percent_Identity=30.976430976431, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647946, Length=296, Percent_Identity=29.3918918918919, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45553409, Length=296, Percent_Identity=29.3918918918919, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647948, Length=296, Percent_Identity=29.3918918918919, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647931, Length=203, Percent_Identity=36.4532019704434, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=232, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=231, Percent_Identity=27.7056277056277, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=222, Percent_Identity=30.6306306306306, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35030; Mature: 35030

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAISALASTLAAQATSRTEPKPDWSTQDMPSQNGRIVLVTGGTSGMGYEDALALTRAG
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCC
AEVIIAARNAERGREAIANIRQAVPEARVQFETLDLANLQSVRDLANRLQGRLPRLDVLI
CEEEEEECCCHHHHHHHHHHHHHCHHHHEEEEHHCHHHHHHHHHHHHHHHCCCCEEEEEE
NNAAIMSPPVRGVSADGYEMQLATNYLGHFALTGLLMPLLRKSDDGRVVSLSSIAAGRAV
CCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCEE
LNFDDLQAERAYDPFTTYSQSKLAVLKWSIELQQRSDAAGWGIRSIAAHPGVAVTELIAR
ECHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEHHCCCCCCCCHHHHHCCCCHHHHHHHHC
GPGLDSEFGKQWAVERDMYHSAAQGALPTLYAATAPEAVGGAYYGPTGDNEKRGPLGFAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCC
MPPAAADRSNSDALWQLSERLTGVTYR
CCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLFAISALASTLAAQATSRTEPKPDWSTQDMPSQNGRIVLVTGGTSGMGYEDALALTRAG
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCC
AEVIIAARNAERGREAIANIRQAVPEARVQFETLDLANLQSVRDLANRLQGRLPRLDVLI
CEEEEEECCCHHHHHHHHHHHHHCHHHHEEEEHHCHHHHHHHHHHHHHHHCCCCEEEEEE
NNAAIMSPPVRGVSADGYEMQLATNYLGHFALTGLLMPLLRKSDDGRVVSLSSIAAGRAV
CCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCEE
LNFDDLQAERAYDPFTTYSQSKLAVLKWSIELQQRSDAAGWGIRSIAAHPGVAVTELIAR
ECHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEHHCCCCCCCCHHHHHCCCCHHHHHHHHC
GPGLDSEFGKQWAVERDMYHSAAQGALPTLYAATAPEAVGGAYYGPTGDNEKRGPLGFAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCC
MPPAAADRSNSDALWQLSERLTGVTYR
CCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]