Click here to switch to the map view.

The map label for this gene is atoS [C]

Identifier: 77458916

GI number: 77458916

Start: 3099826

End: 3101745

Strand: Direct

Name: atoS [C]

Synonym: Pfl01_2691

Alternate gene names: 77458916

Gene position: 3099826-3101745 (Clockwise)

Preceding gene: 77458915

Following gene: 77458917

Centisome position: 48.15

GC content: 61.35

Gene sequence:

>1920_bases
ATGAGCGAGAACAAGAAGTCCGCTGCAATCGAAGACATGCGTTTTCGTTTGCTGATCGATGCGGTGGTCGATTATGCGAT
CTACATGATCGACCCCGAGGGGATCATTACCAGCTGGAACTCCGGCGCCAAGCGCTTCAAGGGATATGAAGAGGCGGAGA
TCCTCGGCGAACACTTTTCCCGGTTCTACACCGATGAAGACCGTGCCAACGGTTTGCCACAGCGGGCACTCGACACGGCA
ATTCGTGAAGGCCGGTTCGAGGGGGAAGGCTGGCGGGTACGCAAGGACGGCACGCATTTCTGGTGCCACGTGGTGATCGA
CCCGATTTTCAGCCCGAGCGGGCAACTGCTCGGGTTTGCCAAGATTACCCGCGACCTGACCGACCGCAAGATGGCCGAAG
AAACCCTCAAGCAGAGCGAACAGCAGTTTCGCCTGCTGGTGCAGGGCGTCACCGACTATGCGATCTACATGCTGAGCCCC
GAAGGCCGGGTGACCAATTGGAACCCCGGCGCGCAGCGGATCAAGGGTTACAAGCCGGATGAGGTCATCGGCCAGCACTT
CTCGATGTTCTACACCCCGGAAGACCGTGAGGCCGGTGAACCCCAGCGGGCCCTGGAAACCGCGGTGCGTGAGGGCCGTT
TCGAGAACAAGAGCTGGCGCCTGCGCAAGGATGGCACGCGGTTTCTGGCCCATGTGGTGGTCGATGCGATTCGCGGCGAC
ACCGGCACCTTGCTCGGTTTTGCCAAGATTACCCGCGACGTCACCGAAGCCACCCAGGCGCAGCAGGCTCTGGAGAAAAC
CCGTGAAGCGCTGTTCCAGGCGCAGAAAATGCAGGCTATTGGCCAACTCAGCGGCGGCATTGCTCACGACTTCAACAATT
TGCTGACGGTGATCCTCGGTAATCTGGAGATCGTGCGCAAACGCGTAGGCGACGACCCGAAAGTCAGCCGTCTGCTGGAG
AACGCCACGCAGGGCGCATTGCGCGGCGTGTCGCTGACCCAACGCATGCTGGCCTTCGCCCGGCGTCAGGAGCTCAAGAC
CGAACCGATCGAAATCCCGAAACTGGTGCAGGGCATCACCGGGCTGTTGCGCAGCTCACTGGGGCCGGGGATCCGCATCG
AAACGCAGTTTCCCGAAGACCTGCAAGCGGTGCTGGCCGACAGCAACCAACTGGAGCTTGCGGTACTCAATCTGGCGACC
AACGCCCGCGACGCCATGCCCGAAGGCGGCAGCGTCACCATCAGTGCCGAACCCGAAGTGGTGCTCGAACAGAACGATTC
AACTCTGGCGGCAGGGCGCTATGTCTGCCTGAGGGTGAACGATACCGGTGAGGGCATGGACGCTGAAACGCTGGCGTCGG
CAACCGATCCGTTTTTCACCACCAAAGGCTTGGGCAAGGGCACGGGTCTGGGGTTGTCGATGGTCCATGGCTTCATCGAA
CAACTGGGTGGCCGCTTCATTCTGAAAAGCACCCAGGGGCAGGGCACCACCGCTGAGCTGTGGTTGCCGGTGGCCATCGA
CGGTGTTGTCGCCAAACCGCTTGGCCCGATGGTGTCCACCGATTCGGTGCCGCGCCTCAGCGTGCTGGTGGTGGATGATG
ACAGTCTGGTGCTCACCAGCACGGTTCTGCTGCTGGAAGACCTCGGCCATCGGGTGCTCAGCGCCACTTCCGGCGCCCAG
GCGCTGGAGCTGTTCGATCAAGGCGAGGTCATCGATCTGATGATCACCGACATGGCCATGCCACAGATGAGTGGCGCGCA
ACTGGCTCACGCCGTGCGCCTGCTCAAGCCGGATCTGCCGATCATCCTCGCCACCGGCTATGCCGAACGCCTCGAGGGTT
TTGCAGCAGGGCTGCCGCGGCTGTCGAAACCGTTCAATCAGCTGAATCTGGTGGAGATCATTGCCCGGTCGATGAAGTGA

Upstream 100 bases:

>100_bases
CTGCCGCGCTGGTGGCAAATCGATCAAGCAGAAGCGGCTGTCCATTCCACCGGTTTGACGCATACTCCTGTCATTGAGAA
TTTGCTTTGAGCCAAGCCTG

Downstream 100 bases:

>100_bases
ACCGGGGGGGCTCGCACGATCCAGCTGAACTTGTCCGCAGCGTGGCGCCTCCAAACGCTTTGTTTACGGAGCGTTTCCCG
TGCCACGCATACTGACCCAA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSENKKSAAIEDMRFRLLIDAVVDYAIYMIDPEGIITSWNSGAKRFKGYEEAEILGEHFSRFYTDEDRANGLPQRALDTA
IREGRFEGEGWRVRKDGTHFWCHVVIDPIFSPSGQLLGFAKITRDLTDRKMAEETLKQSEQQFRLLVQGVTDYAIYMLSP
EGRVTNWNPGAQRIKGYKPDEVIGQHFSMFYTPEDREAGEPQRALETAVREGRFENKSWRLRKDGTRFLAHVVVDAIRGD
TGTLLGFAKITRDVTEATQAQQALEKTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILGNLEIVRKRVGDDPKVSRLLE
NATQGALRGVSLTQRMLAFARRQELKTEPIEIPKLVQGITGLLRSSLGPGIRIETQFPEDLQAVLADSNQLELAVLNLAT
NARDAMPEGGSVTISAEPEVVLEQNDSTLAAGRYVCLRVNDTGEGMDAETLASATDPFFTTKGLGKGTGLGLSMVHGFIE
QLGGRFILKSTQGQGTTAELWLPVAIDGVVAKPLGPMVSTDSVPRLSVLVVDDDSLVLTSTVLLLEDLGHRVLSATSGAQ
ALELFDQGEVIDLMITDMAMPQMSGAQLAHAVRLLKPDLPIILATGYAERLEGFAAGLPRLSKPFNQLNLVEIIARSMK

Sequences:

>Translated_639_residues
MSENKKSAAIEDMRFRLLIDAVVDYAIYMIDPEGIITSWNSGAKRFKGYEEAEILGEHFSRFYTDEDRANGLPQRALDTA
IREGRFEGEGWRVRKDGTHFWCHVVIDPIFSPSGQLLGFAKITRDLTDRKMAEETLKQSEQQFRLLVQGVTDYAIYMLSP
EGRVTNWNPGAQRIKGYKPDEVIGQHFSMFYTPEDREAGEPQRALETAVREGRFENKSWRLRKDGTRFLAHVVVDAIRGD
TGTLLGFAKITRDVTEATQAQQALEKTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILGNLEIVRKRVGDDPKVSRLLE
NATQGALRGVSLTQRMLAFARRQELKTEPIEIPKLVQGITGLLRSSLGPGIRIETQFPEDLQAVLADSNQLELAVLNLAT
NARDAMPEGGSVTISAEPEVVLEQNDSTLAAGRYVCLRVNDTGEGMDAETLASATDPFFTTKGLGKGTGLGLSMVHGFIE
QLGGRFILKSTQGQGTTAELWLPVAIDGVVAKPLGPMVSTDSVPRLSVLVVDDDSLVLTSTVLLLEDLGHRVLSATSGAQ
ALELFDQGEVIDLMITDMAMPQMSGAQLAHAVRLLKPDLPIILATGYAERLEGFAAGLPRLSKPFNQLNLVEIIARSMK
>Mature_638_residues
SENKKSAAIEDMRFRLLIDAVVDYAIYMIDPEGIITSWNSGAKRFKGYEEAEILGEHFSRFYTDEDRANGLPQRALDTAI
REGRFEGEGWRVRKDGTHFWCHVVIDPIFSPSGQLLGFAKITRDLTDRKMAEETLKQSEQQFRLLVQGVTDYAIYMLSPE
GRVTNWNPGAQRIKGYKPDEVIGQHFSMFYTPEDREAGEPQRALETAVREGRFENKSWRLRKDGTRFLAHVVVDAIRGDT
GTLLGFAKITRDVTEATQAQQALEKTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILGNLEIVRKRVGDDPKVSRLLEN
ATQGALRGVSLTQRMLAFARRQELKTEPIEIPKLVQGITGLLRSSLGPGIRIETQFPEDLQAVLADSNQLELAVLNLATN
ARDAMPEGGSVTISAEPEVVLEQNDSTLAAGRYVCLRVNDTGEGMDAETLASATDPFFTTKGLGKGTGLGLSMVHGFIEQ
LGGRFILKSTQGQGTTAELWLPVAIDGVVAKPLGPMVSTDSVPRLSVLVVDDDSLVLTSTVLLLEDLGHRVLSATSGAQA
LELFDQGEVIDLMITDMAMPQMSGAQLAHAVRLLKPDLPIILATGYAERLEGFAAGLPRLSKPFNQLNLVEIIARSMK

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=27.5324675324675, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=29.4871794871795, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788713, Length=383, Percent_Identity=27.6762402088773, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=541, Percent_Identity=22.365988909427, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=360, Percent_Identity=24.7222222222222, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=27.9527559055118, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70251; Mature: 70120

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENKKSAAIEDMRFRLLIDAVVDYAIYMIDPEGIITSWNSGAKRFKGYEEAEILGEHFS
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCHHHHCCCHHHHHHHHHHH
RFYTDEDRANGLPQRALDTAIREGRFEGEGWRVRKDGTHFWCHVVIDPIFSPSGQLLGFA
HHCCCCHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCEEEHH
KITRDLTDRKMAEETLKQSEQQFRLLVQGVTDYAIYMLSPEGRVTNWNPGAQRIKGYKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCCCCCCH
EVIGQHFSMFYTPEDREAGEPQRALETAVREGRFENKSWRLRKDGTRFLAHVVVDAIRGD
HHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHCCC
TGTLLGFAKITRDVTEATQAQQALEKTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
NLEIVRKRVGDDPKVSRLLENATQGALRGVSLTQRMLAFARRQELKTEPIEIPKLVQGIT
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
GLLRSSLGPGIRIETQFPEDLQAVLADSNQLELAVLNLATNARDAMPEGGSVTISAEPEV
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCEEEEEEEECCCHHHCCCCCCEEEEECCCCE
VLEQNDSTLAAGRYVCLRVNDTGEGMDAETLASATDPFFTTKGLGKGTGLGLSMVHGFIE
EEECCCCEEECCCEEEEEECCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHH
QLGGRFILKSTQGQGTTAELWLPVAIDGVVAKPLGPMVSTDSVPRLSVLVVDDDSLVLTS
HHCCEEEEEECCCCCCEEEEEEEEEECCCHHCCCCCCCCCCCCCCEEEEEECCCCCHHHH
TVLLLEDLGHRVLSATSGAQALELFDQGEVIDLMITDMAMPQMSGAQLAHAVRLLKPDLP
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHCCCCC
IILATGYAERLEGFAAGLPRLSKPFNQLNLVEIIARSMK
EEEECCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SENKKSAAIEDMRFRLLIDAVVDYAIYMIDPEGIITSWNSGAKRFKGYEEAEILGEHFS
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCHHHHCCCHHHHHHHHHHH
RFYTDEDRANGLPQRALDTAIREGRFEGEGWRVRKDGTHFWCHVVIDPIFSPSGQLLGFA
HHCCCCHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCEEEHH
KITRDLTDRKMAEETLKQSEQQFRLLVQGVTDYAIYMLSPEGRVTNWNPGAQRIKGYKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHCCCCCCH
EVIGQHFSMFYTPEDREAGEPQRALETAVREGRFENKSWRLRKDGTRFLAHVVVDAIRGD
HHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHCCC
TGTLLGFAKITRDVTEATQAQQALEKTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
NLEIVRKRVGDDPKVSRLLENATQGALRGVSLTQRMLAFARRQELKTEPIEIPKLVQGIT
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
GLLRSSLGPGIRIETQFPEDLQAVLADSNQLELAVLNLATNARDAMPEGGSVTISAEPEV
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCEEEEEEEECCCHHHCCCCCCEEEEECCCCE
VLEQNDSTLAAGRYVCLRVNDTGEGMDAETLASATDPFFTTKGLGKGTGLGLSMVHGFIE
EEECCCCEEECCCEEEEEECCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHH
QLGGRFILKSTQGQGTTAELWLPVAIDGVVAKPLGPMVSTDSVPRLSVLVVDDDSLVLTS
HHCCEEEEEECCCCCCEEEEEEEEEECCCHHCCCCCCCCCCCCCCEEEEEECCCCCHHHH
TVLLLEDLGHRVLSATSGAQALELFDQGEVIDLMITDMAMPQMSGAQLAHAVRLLKPDLP
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHCCCCC
IILATGYAERLEGFAAGLPRLSKPFNQLNLVEIIARSMK
EEEECCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA