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The map label for this gene is opdE [H]

Identifier: 77458700

GI number: 77458700

Start: 2829816

End: 2831024

Strand: Direct

Name: opdE [H]

Synonym: Pfl01_2475

Alternate gene names: 77458700

Gene position: 2829816-2831024 (Clockwise)

Preceding gene: 77458695

Following gene: 77458705

Centisome position: 43.95

GC content: 61.95

Gene sequence:

>1209_bases
ATGACGTTTCCTTCTACAGATCCTTCCAAAAGAACAGGCGGCTGGAGCGCGGTGCTGGCGATGTCGCTGGCCGCATTCGC
TCTGGTCGCTTCCGAGTTCATGCCCGTCAGCCTGCTGACGCCGATTGCGGCGGACCTGCACATCACCGAAGGTCAGGCCG
GGCAGGGTATTTCCGTGTCCGGTGCCTTTGCATTGATCACCAGTCTGTTGATTGCCTCGGTCGCCGCTCGCGTCGAACGC
AAGAAGCTTCTGCTTTGCCTGACCTTGTTGATGATCGTCTCCGGAACGGTCGTCGCACTCGCCCCGGGCTACCCGTCGTT
CATGTTCGGACGTGCGTTGATCGGGATTGCGATTGGTGGTTTCTGGTCGCTATCGGCGGCGACTGCCATGCGCCTGGTGA
AGCCTGAACAGGTTTCCCGTGCGCTGGCCATCGTCAATGGCGGCAACGCTTTGGCCACGGTCATCGCCGCTCCGGCCGGC
AGCTTCCTTGGCTCGTTGATCGGCTGGCGCGGCGCATTCTTCTGTGTGGTTCCAGTCGCAGCGCTTGCCGCCGTGTGGCT
GCTGATCAGCCTGCCGTCCTTCAAGGCCGAGCGCCAGGCCGGTAGCGGCAACGTTCTGCGGTTGATGAGGCAATTGCCAG
TGGCTTTGGGCATGGTCGCCGTCAGCGTCTTTTTCATGGGCCAGTTCATGCTGTTCACTTACCTGCGGCCATTTCTCGAA
GGGGTCACCGGTGTCAGTGTTTCAACATTGTCTTTGATGCTACTGGGCCTGGGGCTGGCAGGTTTTATCGGCACCTTTCT
GATCGAACGGTTTATGGGGCGTGGCCTCTATCGCACGTTGACCGCCATTCCGCTGATCATGGCGGTGATCGCGCTGGCGT
TGGTCAGCTTCGGCAAATCGCCGGTGCTGACCGCCGTGTTGCTCGGACTTTGGGGACTGGTCGCCACAGCTGCGCCGGTT
GGCTGGTGGACGTGGCTGGCGCAGACGCTTCCGGATGACGCGGAAGCCGGAGGCGGCTTGCTGGTGGCCATCGTCCAACT
GGCGATCGCCGGCGGCGCAATCGTTGGCGGCCTGGCGTTTGATCTGAGCGGTTACAAAGCCACCTTCGAGCTTAGCGCCG
CTGTTCTGGTCGCCGCGTCTGTGCTGGCCTGGCTGGCCGGACGCAATGCCACGGAAGTTCATCTTGTCGAGCCGAACGCG
ACAGCCTGA

Upstream 100 bases:

>100_bases
AGAATGTGTCTATCTGTTACAGGGGCACAGCCCGGACGGGCGACAAGCCGCTTGCCCCTGCGCATCACCCCCTACGTTTT
TCGCACCACAGGTAGTTCCC

Downstream 100 bases:

>100_bases
CGAGATCACCTGCAACCTTCCTTATGGCTCAAGCATCAAACTGCGCCAAACGATAACGGGCGGTTCAACCCGCGCAACAT
CCGGTTGCGGCGCTTGCTGT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTFPSTDPSKRTGGWSAVLAMSLAAFALVASEFMPVSLLTPIAADLHITEGQAGQGISVSGAFALITSLLIASVAARVER
KKLLLCLTLLMIVSGTVVALAPGYPSFMFGRALIGIAIGGFWSLSAATAMRLVKPEQVSRALAIVNGGNALATVIAAPAG
SFLGSLIGWRGAFFCVVPVAALAAVWLLISLPSFKAERQAGSGNVLRLMRQLPVALGMVAVSVFFMGQFMLFTYLRPFLE
GVTGVSVSTLSLMLLGLGLAGFIGTFLIERFMGRGLYRTLTAIPLIMAVIALALVSFGKSPVLTAVLLGLWGLVATAAPV
GWWTWLAQTLPDDAEAGGGLLVAIVQLAIAGGAIVGGLAFDLSGYKATFELSAAVLVAASVLAWLAGRNATEVHLVEPNA
TA

Sequences:

>Translated_402_residues
MTFPSTDPSKRTGGWSAVLAMSLAAFALVASEFMPVSLLTPIAADLHITEGQAGQGISVSGAFALITSLLIASVAARVER
KKLLLCLTLLMIVSGTVVALAPGYPSFMFGRALIGIAIGGFWSLSAATAMRLVKPEQVSRALAIVNGGNALATVIAAPAG
SFLGSLIGWRGAFFCVVPVAALAAVWLLISLPSFKAERQAGSGNVLRLMRQLPVALGMVAVSVFFMGQFMLFTYLRPFLE
GVTGVSVSTLSLMLLGLGLAGFIGTFLIERFMGRGLYRTLTAIPLIMAVIALALVSFGKSPVLTAVLLGLWGLVATAAPV
GWWTWLAQTLPDDAEAGGGLLVAIVQLAIAGGAIVGGLAFDLSGYKATFELSAAVLVAASVLAWLAGRNATEVHLVEPNA
TA
>Mature_401_residues
TFPSTDPSKRTGGWSAVLAMSLAAFALVASEFMPVSLLTPIAADLHITEGQAGQGISVSGAFALITSLLIASVAARVERK
KLLLCLTLLMIVSGTVVALAPGYPSFMFGRALIGIAIGGFWSLSAATAMRLVKPEQVSRALAIVNGGNALATVIAAPAGS
FLGSLIGWRGAFFCVVPVAALAAVWLLISLPSFKAERQAGSGNVLRLMRQLPVALGMVAVSVFFMGQFMLFTYLRPFLEG
VTGVSVSTLSLMLLGLGLAGFIGTFLIERFMGRGLYRTLTAIPLIMAVIALALVSFGKSPVLTAVLLGLWGLVATAAPVG
WWTWLAQTLPDDAEAGGGLLVAIVQLAIAGGAIVGGLAFDLSGYKATFELSAAVLVAASVLAWLAGRNATEVHLVEPNAT
A

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=369, Percent_Identity=39.5663956639566, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787808, Length=245, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787947, Length=297, Percent_Identity=27.9461279461279, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786595, Length=309, Percent_Identity=25.5663430420712, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41478; Mature: 41347

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPSTDPSKRTGGWSAVLAMSLAAFALVASEFMPVSLLTPIAADLHITEGQAGQGISVS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCCCC
GAFALITSLLIASVAARVERKKLLLCLTLLMIVSGTVVALAPGYPSFMFGRALIGIAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHH
FWSLSAATAMRLVKPEQVSRALAIVNGGNALATVIAAPAGSFLGSLIGWRGAFFCVVPVA
HHHHHHHHHHHHCCHHHHHHHHHEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
ALAAVWLLISLPSFKAERQAGSGNVLRLMRQLPVALGMVAVSVFFMGQFMLFTYLRPFLE
HHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVTGVSVSTLSLMLLGLGLAGFIGTFLIERFMGRGLYRTLTAIPLIMAVIALALVSFGKS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PVLTAVLLGLWGLVATAAPVGWWTWLAQTLPDDAEAGGGLLVAIVQLAIAGGAIVGGLAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
DLSGYKATFELSAAVLVAASVLAWLAGRNATEVHLVEPNATA
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TFPSTDPSKRTGGWSAVLAMSLAAFALVASEFMPVSLLTPIAADLHITEGQAGQGISVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCCCC
GAFALITSLLIASVAARVERKKLLLCLTLLMIVSGTVVALAPGYPSFMFGRALIGIAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHH
FWSLSAATAMRLVKPEQVSRALAIVNGGNALATVIAAPAGSFLGSLIGWRGAFFCVVPVA
HHHHHHHHHHHHCCHHHHHHHHHEEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
ALAAVWLLISLPSFKAERQAGSGNVLRLMRQLPVALGMVAVSVFFMGQFMLFTYLRPFLE
HHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVTGVSVSTLSLMLLGLGLAGFIGTFLIERFMGRGLYRTLTAIPLIMAVIALALVSFGKS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PVLTAVLLGLWGLVATAAPVGWWTWLAQTLPDDAEAGGGLLVAIVQLAIAGGAIVGGLAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
DLSGYKATFELSAAVLVAASVLAWLAGRNATEVHLVEPNATA
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]