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The map label for this gene is ptxR [H]

Identifier: 77457171

GI number: 77457171

Start: 1096409

End: 1097290

Strand: Direct

Name: ptxR [H]

Synonym: Pfl01_0944

Alternate gene names: 77457171

Gene position: 1096409-1097290 (Clockwise)

Preceding gene: 77457168

Following gene: 77457174

Centisome position: 17.03

GC content: 63.15

Gene sequence:

>882_bases
ATGGTCAGCCTGGATCGATTCGATACCTTCAAAGCCGTGGTCGAGGCCGGCTCGCTGACCGCAGCCGCTGACACGCTGGG
GCAAACGCGGGCGGTGGTGAGCTTCAACCTCAAACGTCTTGAGGAAGAGTTGGGCGTCACCTTGCTCACCCGCAACACCC
GGCAACTGGCCCTGACCGATGCCGGAGAGCGTTTTTATCGGCGCTGCCTGCGCACGCTGGACGAAGCACGGCTGGCCGTC
GAGGAAGCGCGCTCGGAACACTCACAACTCAAAGGCACCCTGCGCATCACCACGACCGTGGAGTTCGCGCTGGCGCAGGT
GGTGCCGGCGCTGGAAGTGTTTCGACAACAGCAGCCGCAACTGAATATTCACTTATCCACATCCTCGACCCACGCCGATC
TGATCTCCGAACGGTTCGACCTGGCGATCCGTTTGGGACGCATGCTCGACTCCAATCTGCGCGCGGTGCAGTTGTCGACA
TTCGAGGTGTTTGCCGTGGCGGCGCCGGGACTGATCGAGCGTTTTGCGCCGGTCGATACGCTGGCGGTGCTGGAGTCGAT
GCCGACGCTGGGGCATGGTCGAGTGCCGGAAATGACGGTCAGCGACCCGGCCGGCACCGAGCATATCTACCAGCCAAAAC
CGGGAACCACCGCCATCGTCGCCGACAACTCGGCGACCCTGCGCGCCTTTGCGCTGACCGGGCAAGGCGTCGCGATTCTG
CCGCAGTGGCTGATTCAGGAAGACCTGGATGCCGGGCGATTGCAGCGCTTGCTGCCGGATTACCGCTTCGCCCAGCAAGG
GGTTTATGCGCTTTACCCGGACACCCGGCACCTGCCACTGAAGGTGCGGGCGTTCATTGATTTCATGAAGGGCCGGCGCT
GA

Upstream 100 bases:

>100_bases
CTGTGATGAGGCGTGCAGGGTAGGGCGCTGGCGGTAATAGAAATACGCTGGTTTGGCTGCTAGTTTGTCAAAATTATTTT
GACACCGGAGCGCTGCGAAC

Downstream 100 bases:

>100_bases
CTCTGTCTCAGAGTTGCCGGCGCAAGCCGAAGCGCTTCATCAATGTCGACTCCAGCAACCCCTTCGGCAGTAACGTCGCC
AGCAACGGCAACGCCCGGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MVSLDRFDTFKAVVEAGSLTAAADTLGQTRAVVSFNLKRLEEELGVTLLTRNTRQLALTDAGERFYRRCLRTLDEARLAV
EEARSEHSQLKGTLRITTTVEFALAQVVPALEVFRQQQPQLNIHLSTSSTHADLISERFDLAIRLGRMLDSNLRAVQLST
FEVFAVAAPGLIERFAPVDTLAVLESMPTLGHGRVPEMTVSDPAGTEHIYQPKPGTTAIVADNSATLRAFALTGQGVAIL
PQWLIQEDLDAGRLQRLLPDYRFAQQGVYALYPDTRHLPLKVRAFIDFMKGRR

Sequences:

>Translated_293_residues
MVSLDRFDTFKAVVEAGSLTAAADTLGQTRAVVSFNLKRLEEELGVTLLTRNTRQLALTDAGERFYRRCLRTLDEARLAV
EEARSEHSQLKGTLRITTTVEFALAQVVPALEVFRQQQPQLNIHLSTSSTHADLISERFDLAIRLGRMLDSNLRAVQLST
FEVFAVAAPGLIERFAPVDTLAVLESMPTLGHGRVPEMTVSDPAGTEHIYQPKPGTTAIVADNSATLRAFALTGQGVAIL
PQWLIQEDLDAGRLQRLLPDYRFAQQGVYALYPDTRHLPLKVRAFIDFMKGRR
>Mature_293_residues
MVSLDRFDTFKAVVEAGSLTAAADTLGQTRAVVSFNLKRLEEELGVTLLTRNTRQLALTDAGERFYRRCLRTLDEARLAV
EEARSEHSQLKGTLRITTTVEFALAQVVPALEVFRQQQPQLNIHLSTSSTHADLISERFDLAIRLGRMLDSNLRAVQLST
FEVFAVAAPGLIERFAPVDTLAVLESMPTLGHGRVPEMTVSDPAGTEHIYQPKPGTTAIVADNSATLRAFALTGQGVAIL
PQWLIQEDLDAGRLQRLLPDYRFAQQGVYALYPDTRHLPLKVRAFIDFMKGRR

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=282, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=32.4137931034483, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=27.8523489932886, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=26.5734265734266, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=29.0102389078498, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=28.125, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=27.3972602739726, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789173, Length=292, Percent_Identity=28.7671232876712, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=27.4576271186441, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786448, Length=287, Percent_Identity=25.0871080139373, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=29.8387096774194, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=254, Percent_Identity=25.5905511811024, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=274, Percent_Identity=24.8175182481752, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=269, Percent_Identity=28.6245353159851, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=24.6666666666667, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32542; Mature: 32542

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLDRFDTFKAVVEAGSLTAAADTLGQTRAVVSFNLKRLEEELGVTLLTRNTRQLALTD
CCCCHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEH
AGERFYRRCLRTLDEARLAVEEARSEHSQLKGTLRITTTVEFALAQVVPALEVFRQQQPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC
LNIHLSTSSTHADLISERFDLAIRLGRMLDSNLRAVQLSTFEVFAVAAPGLIERFAPVDT
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHEEEEEECCCHHHHHHCCHHH
LAVLESMPTLGHGRVPEMTVSDPAGTEHIYQPKPGTTAIVADNSATLRAFALTGQGVAIL
HHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHH
PQWLIQEDLDAGRLQRLLPDYRFAQQGVYALYPDTRHLPLKVRAFIDFMKGRR
HHHHHHHCCCHHHHHHHCCCHHHHHCCEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MVSLDRFDTFKAVVEAGSLTAAADTLGQTRAVVSFNLKRLEEELGVTLLTRNTRQLALTD
CCCCHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEH
AGERFYRRCLRTLDEARLAVEEARSEHSQLKGTLRITTTVEFALAQVVPALEVFRQQQPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC
LNIHLSTSSTHADLISERFDLAIRLGRMLDSNLRAVQLSTFEVFAVAAPGLIERFAPVDT
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHEEEEEECCCHHHHHHCCHHH
LAVLESMPTLGHGRVPEMTVSDPAGTEHIYQPKPGTTAIVADNSATLRAFALTGQGVAIL
HHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHH
PQWLIQEDLDAGRLQRLLPDYRFAQQGVYALYPDTRHLPLKVRAFIDFMKGRR
HHHHHHHCCCHHHHHHHCCCHHHHHCCEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]