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The map label for this gene is hlyB [H]

Identifier: 77456850

GI number: 77456850

Start: 730897

End: 732843

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_0622

Alternate gene names: 77456850

Gene position: 732843-730897 (Counterclockwise)

Preceding gene: 77456851

Following gene: 77456849

Centisome position: 11.38

GC content: 65.43

Gene sequence:

>1947_bases
ATGCGCCTGAAGTTGCTCACCAATCTCAATACTCTGTTGCTGGTCGCCGTCTGCGTGGCCCTCGGCGCCACGCTGTGGTG
GTCGCAAAAAGCCCTGGAGCGCCCGTATCTGTTGATGGAGCGTTACCTGGGGCTGTCGCAGCAATTTCAGAATGTCGTGG
CACGCAACGTCGAGGATTACCTCGCCAGCGGCGACGCCCTGCGCCTGAGCAGCGCCAGTCAGGCCATCGATGATTTGCAG
AAAGAACTCGGTGAGCTGCCGCCCGCGCTGGCCGACACCTTGCGCCCGAGCCTCGCCGACCTCGATGGGTTCAGCAAGAC
CGACCTGCTGGCCGCCGGCAAACTGGCCGGCGATCCGCAGGCCCTGCTGCTGCAGGCCGAGCGCGAATTGAGCGCCAGTC
TCGATCAACTCAGCACCTACGCCGGCGGCAATGCGACTTACCTAACGCCCCTGCTGATTGCCTCTCAACATCTGGGCAAA
CTGTCGCTGGCCCGAGACAAACTGGTCAGCAGCGGACGCAGTGAACTGGCCGCCGATGTCGAGCGCGAAGTCAGCAACAT
CCGCGCCCAGGCCCAGACAATCGATGCCCTGCCCTTGCTCGGCGTGGTCGCCAGCAGTGAGTCCGGCAGCGACGACTTCG
CCGCGATGATGGGCATCGAAAGCACAGCAAAAGCCGCCGCCGAAGATGCCGGGGTCGGCCTCAAACGCGAACTCAACAGT
TTGCTCGGTCGATACCCGGCGGAACTGGCGCGCACCCGCGAGCAGATCCAGAAACGCACCGATCTGAGCACCGCGACTCA
CCAGAAAATCGCCGCCGTGCAACAAGCCATCGCCGGTCTCGAACCCGTGGTGCGCGCCCAGCACGGGCAGATCCAGGGCG
AAGTGCGGCTGATGCAAGGCGTGATGATCGGCCTGATTCTGCTGATCGCGCTGCTGATCGACACCCTGCAGCGACGCCTG
GCCCGCACCCTGACCAACCTCGCGCCGGCGCTGTCGACCTGGGCCGAAGGCGATTTCAGCCGCGACATTCATCTGGGCAA
GACCAACCGCGAACTGCACGACATCGAAGCCTCGCTCAATCGCCTGCGCGCCTATCTGGTGGATCTCGTCGGGACGATTC
GCGGCAATGCCGAGCAAGTGGCCGGCAGCAGCCGCACCCTCGCCGAGCTGAGCAATGACTTGCACAGCGGTGCCGAACAT
CAGGCCGGCGATACCGCGCTGATCCGTGATTCCCTCGGCGAACTGGAAGCGACCATCCAGCAGGTGGCCGGCGATGCACG
GCAGGCCGCCGACGCCAGCCGCCATGCCGGGCTGGCCGTCGAACACGGGCAACAAGTGATCGGCCAGAGCCTCACCGGTC
TGCACGCGTTGGTCGGCGAAGTGCAAGGCAATGCTCAGATGATCGAACACCTGGCCGAAGAGTCGGCAACCATCGGCGGC
GTGCTGACGGTGATCCGCTCGATTGCCGACCAGACCAACCTGCTGGCGCTCAACGCGGCGATCGAAGCCGCCCGCGCCGG
GGAAATGGGCCGCGGGTTTGCCGTGGTGGCCGAGGAAGTGCGCTCGCTGGCACAACGCACCGCCGGCGCCACCGCCGAAA
TCCAGACCCTGATCGCCGGCCTGCAAACCGCCGCCCGGCAATCGGTCGAGGGCATGCGCGCGCAGGTCGAACATGCCGAG
GCCACGGCCAATCAGGCGCAATCGGCGGACGGGGCACTGGACAAGATTGTCGGCGCGATCCAGACCATCTCCGACACCGC
GATCCGCATCGCCGACATCACCGCGCAACAGAGCGGTGCGGTCAGCGAGATCCGCGATCACAGCGAACGGATTCACCAAT
TGGGCGGGGACAATCTGCTGCGCATCGGTCAGGGCCGCGAGCAAGGCGAGAACCTGCTGTTGCTGGGCGGTCAGCTGCAC
ACTGCCGTGCAGGCGTTCCGCGTGTGA

Upstream 100 bases:

>100_bases
AAAGTGCCACTTTTTCATCGGATTCGACCCAATCGGTCATAACCGTGTAACAGAACCGCAATAAATTCAGGCGCTTACCA
TTCTGCCGTTGGTAGCCGTC

Downstream 100 bases:

>100_bases
CACACAGCGCAGGGCCAAGTCCGCTATCATTCCCGCACCTTTGATTCGCGAGATTGTCATGCGCCGTCTGCTCTGCCTGC
TGTTTTTCATCTTCGCCCTG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MRLKLLTNLNTLLLVAVCVALGATLWWSQKALERPYLLMERYLGLSQQFQNVVARNVEDYLASGDALRLSSASQAIDDLQ
KELGELPPALADTLRPSLADLDGFSKTDLLAAGKLAGDPQALLLQAERELSASLDQLSTYAGGNATYLTPLLIASQHLGK
LSLARDKLVSSGRSELAADVEREVSNIRAQAQTIDALPLLGVVASSESGSDDFAAMMGIESTAKAAAEDAGVGLKRELNS
LLGRYPAELARTREQIQKRTDLSTATHQKIAAVQQAIAGLEPVVRAQHGQIQGEVRLMQGVMIGLILLIALLIDTLQRRL
ARTLTNLAPALSTWAEGDFSRDIHLGKTNRELHDIEASLNRLRAYLVDLVGTIRGNAEQVAGSSRTLAELSNDLHSGAEH
QAGDTALIRDSLGELEATIQQVAGDARQAADASRHAGLAVEHGQQVIGQSLTGLHALVGEVQGNAQMIEHLAEESATIGG
VLTVIRSIADQTNLLALNAAIEAARAGEMGRGFAVVAEEVRSLAQRTAGATAEIQTLIAGLQTAARQSVEGMRAQVEHAE
ATANQAQSADGALDKIVGAIQTISDTAIRIADITAQQSGAVSEIRDHSERIHQLGGDNLLRIGQGREQGENLLLLGGQLH
TAVQAFRV

Sequences:

>Translated_648_residues
MRLKLLTNLNTLLLVAVCVALGATLWWSQKALERPYLLMERYLGLSQQFQNVVARNVEDYLASGDALRLSSASQAIDDLQ
KELGELPPALADTLRPSLADLDGFSKTDLLAAGKLAGDPQALLLQAERELSASLDQLSTYAGGNATYLTPLLIASQHLGK
LSLARDKLVSSGRSELAADVEREVSNIRAQAQTIDALPLLGVVASSESGSDDFAAMMGIESTAKAAAEDAGVGLKRELNS
LLGRYPAELARTREQIQKRTDLSTATHQKIAAVQQAIAGLEPVVRAQHGQIQGEVRLMQGVMIGLILLIALLIDTLQRRL
ARTLTNLAPALSTWAEGDFSRDIHLGKTNRELHDIEASLNRLRAYLVDLVGTIRGNAEQVAGSSRTLAELSNDLHSGAEH
QAGDTALIRDSLGELEATIQQVAGDARQAADASRHAGLAVEHGQQVIGQSLTGLHALVGEVQGNAQMIEHLAEESATIGG
VLTVIRSIADQTNLLALNAAIEAARAGEMGRGFAVVAEEVRSLAQRTAGATAEIQTLIAGLQTAARQSVEGMRAQVEHAE
ATANQAQSADGALDKIVGAIQTISDTAIRIADITAQQSGAVSEIRDHSERIHQLGGDNLLRIGQGREQGENLLLLGGQLH
TAVQAFRV
>Mature_648_residues
MRLKLLTNLNTLLLVAVCVALGATLWWSQKALERPYLLMERYLGLSQQFQNVVARNVEDYLASGDALRLSSASQAIDDLQ
KELGELPPALADTLRPSLADLDGFSKTDLLAAGKLAGDPQALLLQAERELSASLDQLSTYAGGNATYLTPLLIASQHLGK
LSLARDKLVSSGRSELAADVEREVSNIRAQAQTIDALPLLGVVASSESGSDDFAAMMGIESTAKAAAEDAGVGLKRELNS
LLGRYPAELARTREQIQKRTDLSTATHQKIAAVQQAIAGLEPVVRAQHGQIQGEVRLMQGVMIGLILLIALLIDTLQRRL
ARTLTNLAPALSTWAEGDFSRDIHLGKTNRELHDIEASLNRLRAYLVDLVGTIRGNAEQVAGSSRTLAELSNDLHSGAEH
QAGDTALIRDSLGELEATIQQVAGDARQAADASRHAGLAVEHGQQVIGQSLTGLHALVGEVQGNAQMIEHLAEESATIGG
VLTVIRSIADQTNLLALNAAIEAARAGEMGRGFAVVAEEVRSLAQRTAGATAEIQTLIAGLQTAARQSVEGMRAQVEHAE
ATANQAQSADGALDKIVGAIQTISDTAIRIADITAQQSGAVSEIRDHSERIHQLGGDNLLRIGQGREQGENLLLLGGQLH
TAVQAFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=31.1688311688312, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=254, Percent_Identity=33.0708661417323, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1788194, Length=271, Percent_Identity=35.0553505535055, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1787690, Length=249, Percent_Identity=33.7349397590361, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789453, Length=307, Percent_Identity=27.3615635179153, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68734; Mature: 68734

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKLLTNLNTLLLVAVCVALGATLWWSQKALERPYLLMERYLGLSQQFQNVVARNVEDY
CCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHH
LASGDALRLSSASQAIDDLQKELGELPPALADTLRPSLADLDGFSKTDLLAAGKLAGDPQ
HCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCCH
ALLLQAERELSASLDQLSTYAGGNATYLTPLLIASQHLGKLSLARDKLVSSGRSELAADV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHH
EREVSNIRAQAQTIDALPLLGVVASSESGSDDFAAMMGIESTAKAAAEDAGVGLKRELNS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
LLGRYPAELARTREQIQKRTDLSTATHQKIAAVQQAIAGLEPVVRAQHGQIQGEVRLMQG
HHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
VMIGLILLIALLIDTLQRRLARTLTNLAPALSTWAEGDFSRDIHLGKTNRELHDIEASLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHH
RLRAYLVDLVGTIRGNAEQVAGSSRTLAELSNDLHSGAEHQAGDTALIRDSLGELEATIQ
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
QVAGDARQAADASRHAGLAVEHGQQVIGQSLTGLHALVGEVQGNAQMIEHLAEESATIGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VLTVIRSIADQTNLLALNAAIEAARAGEMGRGFAVVAEEVRSLAQRTAGATAEIQTLIAG
HHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LQTAARQSVEGMRAQVEHAEATANQAQSADGALDKIVGAIQTISDTAIRIADITAQQSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSEIRDHSERIHQLGGDNLLRIGQGREQGENLLLLGGQLHTAVQAFRV
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCHHHHHHHHHCC
>Mature Secondary Structure
MRLKLLTNLNTLLLVAVCVALGATLWWSQKALERPYLLMERYLGLSQQFQNVVARNVEDY
CCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHH
LASGDALRLSSASQAIDDLQKELGELPPALADTLRPSLADLDGFSKTDLLAAGKLAGDPQ
HCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCCH
ALLLQAERELSASLDQLSTYAGGNATYLTPLLIASQHLGKLSLARDKLVSSGRSELAADV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHH
EREVSNIRAQAQTIDALPLLGVVASSESGSDDFAAMMGIESTAKAAAEDAGVGLKRELNS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
LLGRYPAELARTREQIQKRTDLSTATHQKIAAVQQAIAGLEPVVRAQHGQIQGEVRLMQG
HHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
VMIGLILLIALLIDTLQRRLARTLTNLAPALSTWAEGDFSRDIHLGKTNRELHDIEASLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHH
RLRAYLVDLVGTIRGNAEQVAGSSRTLAELSNDLHSGAEHQAGDTALIRDSLGELEATIQ
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
QVAGDARQAADASRHAGLAVEHGQQVIGQSLTGLHALVGEVQGNAQMIEHLAEESATIGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VLTVIRSIADQTNLLALNAAIEAARAGEMGRGFAVVAEEVRSLAQRTAGATAEIQTLIAG
HHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LQTAARQSVEGMRAQVEHAEATANQAQSADGALDKIVGAIQTISDTAIRIADITAQQSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VSEIRDHSERIHQLGGDNLLRIGQGREQGENLLLLGGQLHTAVQAFRV
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]