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The map label for this gene is dipZ [H]

Identifier: 77456849

GI number: 77456849

Start: 729081

End: 730838

Strand: Reverse

Name: dipZ [H]

Synonym: Pfl01_0621

Alternate gene names: 77456849

Gene position: 730838-729081 (Counterclockwise)

Preceding gene: 77456850

Following gene: 77456848

Centisome position: 11.35

GC content: 63.31

Gene sequence:

>1758_bases
ATGCGCCGTCTGCTCTGCCTGCTGTTTTTCATCTTCGCCCTGCCGGCCGGCGCCGCCGGTCTGTTCGACAGCAAACCCAG
CGCCACACTGGGCTCGGTCAATAACAGTGCCGATTTCCTGCCGGTGCGCGAAGCCTTTCAACTGAGCCTGGTCGAGAGCA
CGCCGCAATCGGTCAAACTGCGCTTCGTTGCCACCGAAGGCTATTACCTCTACCGCCATCGCTTCCAGTTCCGTGCCGAG
CCTGCCGAGGTGAAACTCGGTGCCGCACAACTGCCCCAAGGCGAACAGAAGCACGACGAGTATTTCGGCGACGTCGAGGT
CTACCACGGCATTCTCGATGTAGAACTGCCGCGCAATGATTCCCGGTCGTTCACGCTGGCCGTCACCTATCAGGGCTGTG
CCGACAAGGGTTTGTGCTATCCACCGGAAACCGAACGCCTGAGCATCGAGGGCAACGCGGCGGCAAATGACGCGTCCGCT
CCGGTGGCGGGTTGGGACTGGCGTGATCTGGCGCTGTTTTTCCTGGCGGGCCTGGGCCTGACCTTCACGCCTTGTGTATT
GCCGATGCTGCCGATCCTGTCCGGTGTGGTGTTGCGTGGGCAGGTCGGCGGTTTGCGTGGCTTCAATCTGTCGCTGGCTT
ATGTGCTGCCGATGGCCGCGTGTTTCGCGCTGCTCGGCGCATTGATGGGGCTGTTCGGCGCGCAACTGAATCTGCAGGCA
CGGCTGCAATCGGCTTGGGTACTGGTGCCGTTCGCGATGTTCTTTGCGGTGTTCGCACTGGCGATGTTCGGCGTGTTCGA
GCTGAAACTGCCGCACTTCATCAGCAGCCGACTCGACCGGATTGCCGGGCGCACCGAAGGCGGCTCGTTGTGGGGCGCGG
CGGTGTTGGGCGTGGTGTCGAGTCTGCTGGTCTCGCCGTGCGTTTCCGCACCGCTGGCCGGCGCACTGCTTTATATCAGC
GCCAGCGGCGATGCGCTGGGCGGTGGCCTGAAGCTGTTCATGCTCGGCCTGGGCATGGGCGCGCCGCTGTTGCTGGTGGC
CACCGGCGGCGCGGCGTGGCTGCCGAAAAGCGGGCCGTGGATGATGTACGTGAAGAACGGCATCGGCGTATTGCTGCTCG
GGCTGGCGATCGGCCTGCTCAGCCGGGTACTGCCGGGGCAGATCACGTTGCTGCTGATCGGCTTGCTGGCTGGTGGCGTT
GGCCTGTTCCTCGGTGCTCTGGAATTTGTCTACAAACCGCCGCGCAAACGCCTCGGCCAGCTGCTCGGCCTGTTCCTGCT
GTTTTATGCGCTGGCCTGCTGGTACGGCGCGTTCAGCGGGCAGACCGACCCGTTGAATCCGATAGCCCCGGCACGCCTTG
CCGACAGCGGTTCGACTGCGCAAAACAGCGGTTCGTGGCAGACCGTCAGCACCCCGGCGGAACTGGATCGGGTGCTGCTC
GAAGCGAAAACCGCCGGCACCCCGCTGCTGCTCGACTGGTACGCCGACTGGTGCATCAGCTGCAAAGTCATCGAACACGA
AGTACTCAATGACGCCACAGTCTTGGATCGGCTCAAGGGTTATCGGCTGATCCGCTTCGATATCACCGCCAGCAATGCCG
AACAGCGCACCCTGCTCGACCGCTACAGCCTGTTCGGCCCACCGGCGCTGATGTTCTTCGGCAAGGACGGGGTGGAACGT
CGCGATGTGCGAGTGATCGGCGAGATCAACGCCGGCGACTTCGCCGAACGTGTCGCCAAAGCGAATGACCGGATTTAA

Upstream 100 bases:

>100_bases
GGCGGTCAGCTGCACACTGCCGTGCAGGCGTTCCGCGTGTGACACACAGCGCAGGGCCAAGTCCGCTATCATTCCCGCAC
CTTTGATTCGCGAGATTGTC

Downstream 100 bases:

>100_bases
TCAGTCAGTCACATATTTTGCGCAAACATCGGACATCGTGCTGGCTATTGCAGAGAACTGGACAGTCACAAAGTCTTTGC
GGCATAGTCGCCGGGTTCTG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase 1; Disulfide reductase 1 [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MRRLLCLLFFIFALPAGAAGLFDSKPSATLGSVNNSADFLPVREAFQLSLVESTPQSVKLRFVATEGYYLYRHRFQFRAE
PAEVKLGAAQLPQGEQKHDEYFGDVEVYHGILDVELPRNDSRSFTLAVTYQGCADKGLCYPPETERLSIEGNAAANDASA
PVAGWDWRDLALFFLAGLGLTFTPCVLPMLPILSGVVLRGQVGGLRGFNLSLAYVLPMAACFALLGALMGLFGAQLNLQA
RLQSAWVLVPFAMFFAVFALAMFGVFELKLPHFISSRLDRIAGRTEGGSLWGAAVLGVVSSLLVSPCVSAPLAGALLYIS
ASGDALGGGLKLFMLGLGMGAPLLLVATGGAAWLPKSGPWMMYVKNGIGVLLLGLAIGLLSRVLPGQITLLLIGLLAGGV
GLFLGALEFVYKPPRKRLGQLLGLFLLFYALACWYGAFSGQTDPLNPIAPARLADSGSTAQNSGSWQTVSTPAELDRVLL
EAKTAGTPLLLDWYADWCISCKVIEHEVLNDATVLDRLKGYRLIRFDITASNAEQRTLLDRYSLFGPPALMFFGKDGVER
RDVRVIGEINAGDFAERVAKANDRI

Sequences:

>Translated_585_residues
MRRLLCLLFFIFALPAGAAGLFDSKPSATLGSVNNSADFLPVREAFQLSLVESTPQSVKLRFVATEGYYLYRHRFQFRAE
PAEVKLGAAQLPQGEQKHDEYFGDVEVYHGILDVELPRNDSRSFTLAVTYQGCADKGLCYPPETERLSIEGNAAANDASA
PVAGWDWRDLALFFLAGLGLTFTPCVLPMLPILSGVVLRGQVGGLRGFNLSLAYVLPMAACFALLGALMGLFGAQLNLQA
RLQSAWVLVPFAMFFAVFALAMFGVFELKLPHFISSRLDRIAGRTEGGSLWGAAVLGVVSSLLVSPCVSAPLAGALLYIS
ASGDALGGGLKLFMLGLGMGAPLLLVATGGAAWLPKSGPWMMYVKNGIGVLLLGLAIGLLSRVLPGQITLLLIGLLAGGV
GLFLGALEFVYKPPRKRLGQLLGLFLLFYALACWYGAFSGQTDPLNPIAPARLADSGSTAQNSGSWQTVSTPAELDRVLL
EAKTAGTPLLLDWYADWCISCKVIEHEVLNDATVLDRLKGYRLIRFDITASNAEQRTLLDRYSLFGPPALMFFGKDGVER
RDVRVIGEINAGDFAERVAKANDRI
>Mature_585_residues
MRRLLCLLFFIFALPAGAAGLFDSKPSATLGSVNNSADFLPVREAFQLSLVESTPQSVKLRFVATEGYYLYRHRFQFRAE
PAEVKLGAAQLPQGEQKHDEYFGDVEVYHGILDVELPRNDSRSFTLAVTYQGCADKGLCYPPETERLSIEGNAAANDASA
PVAGWDWRDLALFFLAGLGLTFTPCVLPMLPILSGVVLRGQVGGLRGFNLSLAYVLPMAACFALLGALMGLFGAQLNLQA
RLQSAWVLVPFAMFFAVFALAMFGVFELKLPHFISSRLDRIAGRTEGGSLWGAAVLGVVSSLLVSPCVSAPLAGALLYIS
ASGDALGGGLKLFMLGLGMGAPLLLVATGGAAWLPKSGPWMMYVKNGIGVLLLGLAIGLLSRVLPGQITLLLIGLLAGGV
GLFLGALEFVYKPPRKRLGQLLGLFLLFYALACWYGAFSGQTDPLNPIAPARLADSGSTAQNSGSWQTVSTPAELDRVLL
EAKTAGTPLLLDWYADWCISCKVIEHEVLNDATVLDRLKGYRLIRFDITASNAEQRTLLDRYSLFGPPALMFFGKDGVER
RDVRVIGEINAGDFAERVAKANDRI

Specific function: Involved in the formation of correct disulfide bonds in some periplasmic proteins and in the assembly of the periplasmic C-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=578, Percent_Identity=36.5051903114187, Blast_Score=313, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 62940; Mature: 62940

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLCLLFFIFALPAGAAGLFDSKPSATLGSVNNSADFLPVREAFQLSLVESTPQSVKL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
RFVATEGYYLYRHRFQFRAEPAEVKLGAAQLPQGEQKHDEYFGDVEVYHGILDVELPRND
EEEEECCEEEEEEEEHCCCCCCCEEECHHCCCCCCHHHHHHCCCHHHHCCEEEEEECCCC
SRSFTLAVTYQGCADKGLCYPPETERLSIEGNAAANDASAPVAGWDWRDLALFFLAGLGL
CCEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
TFTPCVLPMLPILSGVVLRGQVGGLRGFNLSLAYVLPMAACFALLGALMGLFGAQLNLQA
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RLQSAWVLVPFAMFFAVFALAMFGVFELKLPHFISSRLDRIAGRTEGGSLWGAAVLGVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SLLVSPCVSAPLAGALLYISASGDALGGGLKLFMLGLGMGAPLLLVATGGAAWLPKSGPW
HHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEECCCCCCE
MMYVKNGIGVLLLGLAIGLLSRVLPGQITLLLIGLLAGGVGLFLGALEFVYKPPRKRLGQ
EEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLGLFLLFYALACWYGAFSGQTDPLNPIAPARLADSGSTAQNSGSWQTVSTPAELDRVLL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
EAKTAGTPLLLDWYADWCISCKVIEHEVLNDATVLDRLKGYRLIRFDITASNAEQRTLLD
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEEEECCCCHHHHHHH
RYSLFGPPALMFFGKDGVERRDVRVIGEINAGDFAERVAKANDRI
HHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRRLLCLLFFIFALPAGAAGLFDSKPSATLGSVNNSADFLPVREAFQLSLVESTPQSVKL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
RFVATEGYYLYRHRFQFRAEPAEVKLGAAQLPQGEQKHDEYFGDVEVYHGILDVELPRND
EEEEECCEEEEEEEEHCCCCCCCEEECHHCCCCCCHHHHHHCCCHHHHCCEEEEEECCCC
SRSFTLAVTYQGCADKGLCYPPETERLSIEGNAAANDASAPVAGWDWRDLALFFLAGLGL
CCEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
TFTPCVLPMLPILSGVVLRGQVGGLRGFNLSLAYVLPMAACFALLGALMGLFGAQLNLQA
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RLQSAWVLVPFAMFFAVFALAMFGVFELKLPHFISSRLDRIAGRTEGGSLWGAAVLGVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SLLVSPCVSAPLAGALLYISASGDALGGGLKLFMLGLGMGAPLLLVATGGAAWLPKSGPW
HHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEECCCCCCE
MMYVKNGIGVLLLGLAIGLLSRVLPGQITLLLIGLLAGGVGLFLGALEFVYKPPRKRLGQ
EEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLGLFLLFYALACWYGAFSGQTDPLNPIAPARLADSGSTAQNSGSWQTVSTPAELDRVLL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
EAKTAGTPLLLDWYADWCISCKVIEHEVLNDATVLDRLKGYRLIRFDITASNAEQRTLLD
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEEEECCCCHHHHHHH
RYSLFGPPALMFFGKDGVERRDVRVIGEINAGDFAERVAKANDRI
HHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353916; 10984043 [H]