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The map label for this gene is prmA [H]

Identifier: 77456845

GI number: 77456845

Start: 725580

End: 726458

Strand: Reverse

Name: prmA [H]

Synonym: Pfl01_0617

Alternate gene names: 77456845

Gene position: 726458-725580 (Counterclockwise)

Preceding gene: 77456846

Following gene: 77456844

Centisome position: 11.28

GC content: 65.3

Gene sequence:

>879_bases
ATGCCTTGGCTGCAAGTCCGTCTCGCCATCAGCCCAGAACAAGCCGAAACCTACGAAGACGCTTTTCTTGAAGTGGGCGC
CGTTTCGGTGACCTTCATGGACGCCGAAGATCAGCCGATCTTCGAACCGGAACTCAATACCACCCCGCTGTGGGCGCACA
CCCACCTGCTGGCCCTGTTCGAGGGCGGCACCGAAGCCGCCCCGTTACTGGCCCATCTGGAACTGCTGACCGGCAGCCCG
CTGCCCGAGCACCACAGCGAAGTCATCGAAGACCAGGACTGGGAACGCAGCTGGATGGATGGTTTCCAGCCGATGCGTTT
CGGCCAGCGTCTGTGGATCGTGCCGAGCTGGCACGCCGCCCCGGAGCCGGACGCGGTCAACCTGCTGCTGGACCCGGGCC
TGGCGTTCGGCACCGGCACCCACCCGACCACCGCCCTGTGCCTGGAATGGCTGGACGGCCAGGACCTGAAAGACTGCAAC
GTGCTGGACTTTGGCTGCGGCTCGGGGATTCTGGCGATTGCCGCCCTGCTGCTCGGCGCGAAAGAAGCCGTGGGCACCGA
CATCGATGTGCAGGCGCTGGAAGCGTCCCGCGACAACGCCGGGCGCAACAATATCGCTGACGAACTGTTCCCGCTGTACC
TGCCGGAAGAACTGCCGCAGGTCAAAGCCGACGTACTGGTCGCCAACATTCTGGCCGGCCCGCTGGTTTCCCTGGCGCCG
CAACTGTCCGGCCTGGTCAAGTCCGGCGGGCGTCTGGCACTGTCCGGGATCCTCGCCGAACAAGGTGACGAAGTCGCCGC
TGCCTACGCGCAGGACTTCGATCTCGACCCGATCGCCAATCGTGATGGCTGGGTGCGCATCACCGGCCGTCGGCGCTAG

Upstream 100 bases:

>100_bases
CACACATTCCCCGCTCCCACAAAACCGTCGCGCTCGCGTAAACTTGCGCGCTTGTCGCAGGCCGCTAGGCTGCAATCAAT
CTTTTTCACAGGTGCCCGCC

Downstream 100 bases:

>100_bases
AATGACCGCCTGCTCAATCCGGATCGCCGCATGACCGACAGCTTCGTCACCCAGTGCCCGCATTGCCAAACCAGTTTCCG
CGTCAGCCACGCTCAGTTGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPWLQVRLAISPEQAETYEDAFLEVGAVSVTFMDAEDQPIFEPELNTTPLWAHTHLLALFEGGTEAAPLLAHLELLTGSP
LPEHHSEVIEDQDWERSWMDGFQPMRFGQRLWIVPSWHAAPEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQDLKDCN
VLDFGCGSGILAIAALLLGAKEAVGTDIDVQALEASRDNAGRNNIADELFPLYLPEELPQVKADVLVANILAGPLVSLAP
QLSGLVKSGGRLALSGILAEQGDEVAAAYAQDFDLDPIANRDGWVRITGRRR

Sequences:

>Translated_292_residues
MPWLQVRLAISPEQAETYEDAFLEVGAVSVTFMDAEDQPIFEPELNTTPLWAHTHLLALFEGGTEAAPLLAHLELLTGSP
LPEHHSEVIEDQDWERSWMDGFQPMRFGQRLWIVPSWHAAPEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQDLKDCN
VLDFGCGSGILAIAALLLGAKEAVGTDIDVQALEASRDNAGRNNIADELFPLYLPEELPQVKADVLVANILAGPLVSLAP
QLSGLVKSGGRLALSGILAEQGDEVAAAYAQDFDLDPIANRDGWVRITGRRR
>Mature_291_residues
PWLQVRLAISPEQAETYEDAFLEVGAVSVTFMDAEDQPIFEPELNTTPLWAHTHLLALFEGGTEAAPLLAHLELLTGSPL
PEHHSEVIEDQDWERSWMDGFQPMRFGQRLWIVPSWHAAPEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQDLKDCNV
LDFGCGSGILAIAALLLGAKEAVGTDIDVQALEASRDNAGRNNIADELFPLYLPEELPQVKADVLVANILAGPLVSLAPQ
LSGLVKSGGRLALSGILAEQGDEVAAAYAQDFDLDPIANRDGWVRITGRRR

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=295, Percent_Identity=56.9491525423729, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31670; Mature: 31539

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWLQVRLAISPEQAETYEDAFLEVGAVSVTFMDAEDQPIFEPELNTTPLWAHTHLLALF
CCCEEEEEEECCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHEEEEEE
EGGTEAAPLLAHLELLTGSPLPEHHSEVIEDQDWERSWMDGFQPMRFGQRLWIVPSWHAA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHCCCCHHCCCCEEEEEECCCCC
PEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQDLKDCNVLDFGCGSGILAIAALLLGA
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHCC
KEAVGTDIDVQALEASRDNAGRNNIADELFPLYLPEELPQVKADVLVANILAGPLVSLAP
HHHHCCCCCCEEHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLSGLVKSGGRLALSGILAEQGDEVAAAYAQDFDLDPIANRDGWVRITGRRR
HHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
PWLQVRLAISPEQAETYEDAFLEVGAVSVTFMDAEDQPIFEPELNTTPLWAHTHLLALF
CCEEEEEEECCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHEEEEEE
EGGTEAAPLLAHLELLTGSPLPEHHSEVIEDQDWERSWMDGFQPMRFGQRLWIVPSWHAA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHCCCCHHCCCCEEEEEECCCCC
PEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQDLKDCNVLDFGCGSGILAIAALLLGA
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHCC
KEAVGTDIDVQALEASRDNAGRNNIADELFPLYLPEELPQVKADVLVANILAGPLVSLAP
HHHHCCCCCCEEHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLSGLVKSGGRLALSGILAEQGDEVAAAYAQDFDLDPIANRDGWVRITGRRR
HHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA