Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 77454728

GI number: 77454728

Start: 155861

End: 156847

Strand: Direct

Name: trxB [H]

Synonym: pREL1_0161

Alternate gene names: 77454728

Gene position: 155861-156847 (Clockwise)

Preceding gene: 77454727

Following gene: 77454729

Centisome position: 57.39

GC content: 66.67

Gene sequence:

>987_bases
ATGACCATCCCGTCCGCGGTCCATGACGTCATCATTGTCGGTTCCGGACCGGCCGGCTACACCGCTGGTGTCTACACCGC
GCGCGCTGAGCTCGCGCCCCTGCTCTTCGAGGGAACCCAGTTCGGTGGCGCCCTCATGACCACCACCGAGGTCGAGAACT
TCCCCGGATTCCGCGAAGGAATCATGGGCCCCGATCTGATGGAACAGATGCGCGAGCAGGCACTGCGCTTCGACACCGAC
ATCCGCACCGAGGACGTCGAGGAGATCGATCTCAGCGGCCCGATCAAGACGGTCGTCGCGAACGGCGAAACCTACGCCGC
GCACGCGATCATCCTCGCCATGGGCGCAGCAGCCCGCTACCTGGGCATTCCCGGTGAAGAACGCCTCCTCGGCCGCGGCG
TCAGCGCCTGCGCCACCTGCGACGGCTTCTTCTTCCGTGACCAGGACATCGTCGTGGTCGGCGGCGGCGATTCCGCGATG
GAAGAAGCAACCTTCCTCACCCGCTTCGCTCGCTCGGTCACCCTGGTGCACCGCCGCGAGGAGTTCCGCGCCTCACGGAT
CATGCTCGAGCGCGCCAAGGCCAACGAGAAGATCCGCTTCCTGACCAACGCAGAGCCCGTCGAGGTGCTCGGTGAGAACA
GCGTCACCGGCCTCGTCGTGCGCGACACCGTCACCGGCGAAACTTCCACACTCGAGATCACCGGCATGTTCGTCGCCATC
GGCCACGACCCGCGCAGTGAGCTCGTCAAGGACCAGGTCGATCTCGACGACGCCGGATACGTGCGCGTCGCTCCCGGTTC
CACCGCGACCTCCGTCGACGGCGTCTTCGCTGCCGGTGACCTGGTCGATCACACGTACCGTCAGGCGATCACCGCTGCCG
GCACCGGATGCTCCGCAGCAATCGACGCCGAACGCTGGCTGGCCGACCGCGGCGACATCACCGCCAACACGCTCGACGCA
GCCGGCCACACCGTAGACGCCGTCTGA

Upstream 100 bases:

>100_bases
TCAAAACCCGCGTCCAAGCCTTGATCAGCGAACTCACCGCCCCGTCGGTATCGCGCTGACCGCTCGTACTGCCCGTATTC
GATCCCGTGAAAGAGACACT

Downstream 100 bases:

>100_bases
CTCCCACACCCAGCGAAAGGAACTTCGATGAGCAAGCCTTCAGTGCTGTTCGTGTGCGTCAAGAACGGCGGCAAATCCCA
GATGGCCGCCGGCCTCATGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTIPSAVHDVIIVGSGPAGYTAGVYTARAELAPLLFEGTQFGGALMTTTEVENFPGFREGIMGPDLMEQMREQALRFDTD
IRTEDVEEIDLSGPIKTVVANGETYAAHAIILAMGAAARYLGIPGEERLLGRGVSACATCDGFFFRDQDIVVVGGGDSAM
EEATFLTRFARSVTLVHRREEFRASRIMLERAKANEKIRFLTNAEPVEVLGENSVTGLVVRDTVTGETSTLEITGMFVAI
GHDPRSELVKDQVDLDDAGYVRVAPGSTATSVDGVFAAGDLVDHTYRQAITAAGTGCSAAIDAERWLADRGDITANTLDA
AGHTVDAV

Sequences:

>Translated_328_residues
MTIPSAVHDVIIVGSGPAGYTAGVYTARAELAPLLFEGTQFGGALMTTTEVENFPGFREGIMGPDLMEQMREQALRFDTD
IRTEDVEEIDLSGPIKTVVANGETYAAHAIILAMGAAARYLGIPGEERLLGRGVSACATCDGFFFRDQDIVVVGGGDSAM
EEATFLTRFARSVTLVHRREEFRASRIMLERAKANEKIRFLTNAEPVEVLGENSVTGLVVRDTVTGETSTLEITGMFVAI
GHDPRSELVKDQVDLDDAGYVRVAPGSTATSVDGVFAAGDLVDHTYRQAITAAGTGCSAAIDAERWLADRGDITANTLDA
AGHTVDAV
>Mature_327_residues
TIPSAVHDVIIVGSGPAGYTAGVYTARAELAPLLFEGTQFGGALMTTTEVENFPGFREGIMGPDLMEQMREQALRFDTDI
RTEDVEEIDLSGPIKTVVANGETYAAHAIILAMGAAARYLGIPGEERLLGRGVSACATCDGFFFRDQDIVVVGGGDSAME
EATFLTRFARSVTLVHRREEFRASRIMLERAKANEKIRFLTNAEPVEVLGENSVTGLVVRDTVTGETSTLEITGMFVAIG
HDPRSELVKDQVDLDDAGYVRVAPGSTATSVDGVFAAGDLVDHTYRQAITAAGTGCSAAIDAERWLADRGDITANTLDAA
GHTVDAV

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=50.6493506493506, Blast_Score=299, Evalue=1e-82,
Organism=Escherichia coli, GI87081763, Length=313, Percent_Identity=33.5463258785943, Blast_Score=145, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=48.7261146496815, Blast_Score=298, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=46.9648562300319, Blast_Score=288, Evalue=8e-79,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34910; Mature: 34778

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPSAVHDVIIVGSGPAGYTAGVYTARAELAPLLFEGTQFGGALMTTTEVENFPGFREG
CCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHEEECCCCCCEEEEEEECCCCCCHHHC
IMGPDLMEQMREQALRFDTDIRTEDVEEIDLSGPIKTVVANGETYAAHAIILAMGAAARY
CCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
LGIPGEERLLGRGVSACATCDGFFFRDQDIVVVGGGDSAMEEATFLTRFARSVTLVHRRE
CCCCCHHHHHHCCCHHHHHCCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EFRASRIMLERAKANEKIRFLTNAEPVEVLGENSVTGLVVRDTVTGETSTLEITGMFVAI
HHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCEEEEEEEEEECCCCCEEEEEEEEEEE
GHDPRSELVKDQVDLDDAGYVRVAPGSTATSVDGVFAAGDLVDHTYRQAITAAGTGCSAA
CCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCE
IDAERWLADRGDITANTLDAAGHTVDAV
ECHHHHHCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure 
TIPSAVHDVIIVGSGPAGYTAGVYTARAELAPLLFEGTQFGGALMTTTEVENFPGFREG
CCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHEEECCCCCCEEEEEEECCCCCCHHHC
IMGPDLMEQMREQALRFDTDIRTEDVEEIDLSGPIKTVVANGETYAAHAIILAMGAAARY
CCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
LGIPGEERLLGRGVSACATCDGFFFRDQDIVVVGGGDSAMEEATFLTRFARSVTLVHRRE
CCCCCHHHHHHCCCHHHHHCCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EFRASRIMLERAKANEKIRFLTNAEPVEVLGENSVTGLVVRDTVTGETSTLEITGMFVAI
HHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCEEEEEEEEEECCCCCEEEEEEEEEEE
GHDPRSELVKDQVDLDDAGYVRVAPGSTATSVDGVFAAGDLVDHTYRQAITAAGTGCSAA
CCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCE
IDAERWLADRGDITANTLDAAGHTVDAV
ECHHHHHCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]