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The map label for this gene is arsB [H]

Identifier: 77454726

GI number: 77454726

Start: 154318

End: 155406

Strand: Direct

Name: arsB [H]

Synonym: pREL1_0159

Alternate gene names: 77454726

Gene position: 154318-155406 (Clockwise)

Preceding gene: 77454725

Following gene: 77454727

Centisome position: 56.82

GC content: 62.9

Gene sequence:

>1089_bases
ATGAGCGCCCCGTCCAGTACCGAACACCCCGAAGTCGTCGGAAAACTCTCCACCCTCGACCGCTATCTGGCGGTCTGGAT
CGGCGTGGCCATGGTCGTCGGCCTGCTGGTTGGACGCTGGATCCCCGGCGTGAACACTGCCCTGGACAAGGTGCAGATCG
ACGGCATCTCGTTACCGATCGCCCTCGGCCTGCTGATCATGATGTACCCGGTGTTGGCGAAAGTTCGCTACGACCGCCTC
GACACTGTCACCGGGGACAAGAAACTCCTCGCCGGCTCCCTGTTCCTGAACTGGGTTCTCGGCCCGGCGCTGATGTTCGC
CCTCGCCTGGCTGTTTCTGCCTGACCTGCCGGAATACCGAACCGGTTTGATCATCGTCGGCATCGCTCGCTGCATCGCGA
TGGTGATCATCTGGAACGACCTGGCCTGCGGAGACCGCGAAGCCGCCGCGGTGCTGGTCGCCATCAACTCGGTGTTCCAG
GTGATCATGTTCGCCGTGCTCGGTTGGTTCTACCTCTCGGTCCTGCCCGGGTGGCTCGGCCTCGAACAGACCACCATCGA
CACCTCGCCCTGGCAGATCGCGAAATCGGTCCTGATCTTCCTCGGTATCCCGCTGCTGGCAGGTTTTCTGTCCCGCTTCT
TCGGTGAACGCGCCAAAGACCGCGACTGGTACGACAACAAGTTCATCCCCAAGATCAGCCCCTGGGCGCTCTACGGTCTG
CTGTTCACCATCGTCGTGCTCTTCTCGATGCAGGGCGAACAGATCACCTCCCAGCCCTGGGACGTCGTCCGGATCGCGCT
GCCCTTGCTCGCGTACTTCGCGCTCATGTGGGGCGGAGGCTACGTCCTCGGCGCCGCAATCGGATTGGGCTATGAACGCA
CGACGACCCTGGCGTTCACCGCCGCGGGCAACAACTTCGAACTCGCGATCGCCGTAGCCATCGCCACCTACGGCGCCACC
TCGGGGCAAGCTCTTGCCGGCGTAGTCGGCCCGCTGATCGAGGTACCGGTGCTCGTCGGGCTGGTCTATGTCTCCCTTGC
TCTACGCAAACGCTTCACACCCACTGACGGAAAGGTTTCAGCCCCATGA

Upstream 100 bases:

>100_bases
TGTACTACTGGGTGATACCCGCAGCCCTGCAACAACTTTCCGCCGTTCTGCTCGTGGAAGCATCATCCACTGCCGCCGAC
GTCCCACAGGAGACCGCCGT

Downstream 100 bases:

>100_bases
CCGACAAGCCCAGCGTCCTGTTCGTCTGTGTCCACAACGCCGGCCGATCGCAGATGGCCGCGGGATTCCTGAGCCACCTC
GCCGGCGATGCCATCGAGGT

Product: putative arsenite export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSAPSSTEHPEVVGKLSTLDRYLAVWIGVAMVVGLLVGRWIPGVNTALDKVQIDGISLPIALGLLIMMYPVLAKVRYDRL
DTVTGDKKLLAGSLFLNWVLGPALMFALAWLFLPDLPEYRTGLIIVGIARCIAMVIIWNDLACGDREAAAVLVAINSVFQ
VIMFAVLGWFYLSVLPGWLGLEQTTIDTSPWQIAKSVLIFLGIPLLAGFLSRFFGERAKDRDWYDNKFIPKISPWALYGL
LFTIVVLFSMQGEQITSQPWDVVRIALPLLAYFALMWGGGYVLGAAIGLGYERTTTLAFTAAGNNFELAIAVAIATYGAT
SGQALAGVVGPLIEVPVLVGLVYVSLALRKRFTPTDGKVSAP

Sequences:

>Translated_362_residues
MSAPSSTEHPEVVGKLSTLDRYLAVWIGVAMVVGLLVGRWIPGVNTALDKVQIDGISLPIALGLLIMMYPVLAKVRYDRL
DTVTGDKKLLAGSLFLNWVLGPALMFALAWLFLPDLPEYRTGLIIVGIARCIAMVIIWNDLACGDREAAAVLVAINSVFQ
VIMFAVLGWFYLSVLPGWLGLEQTTIDTSPWQIAKSVLIFLGIPLLAGFLSRFFGERAKDRDWYDNKFIPKISPWALYGL
LFTIVVLFSMQGEQITSQPWDVVRIALPLLAYFALMWGGGYVLGAAIGLGYERTTTLAFTAAGNNFELAIAVAIATYGAT
SGQALAGVVGPLIEVPVLVGLVYVSLALRKRFTPTDGKVSAP
>Mature_361_residues
SAPSSTEHPEVVGKLSTLDRYLAVWIGVAMVVGLLVGRWIPGVNTALDKVQIDGISLPIALGLLIMMYPVLAKVRYDRLD
TVTGDKKLLAGSLFLNWVLGPALMFALAWLFLPDLPEYRTGLIIVGIARCIAMVIIWNDLACGDREAAAVLVAINSVFQV
IMFAVLGWFYLSVLPGWLGLEQTTIDTSPWQIAKSVLIFLGIPLLAGFLSRFFGERAKDRDWYDNKFIPKISPWALYGLL
FTIVVLFSMQGEQITSQPWDVVRIALPLLAYFALMWGGGYVLGAAIGLGYERTTTLAFTAAGNNFELAIAVAIATYGATS
GQALAGVVGPLIEVPVLVGLVYVSLALRKRFTPTDGKVSAP

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=348, Percent_Identity=35.0574712643678, Blast_Score=187, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39255; Mature: 39124

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSSTEHPEVVGKLSTLDRYLAVWIGVAMVVGLLVGRWIPGVNTALDKVQIDGISLPI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCHHH
ALGLLIMMYPVLAKVRYDRLDTVTGDKKLLAGSLFLNWVLGPALMFALAWLFLPDLPEYR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TGLIIVGIARCIAMVIIWNDLACGDREAAAVLVAINSVFQVIMFAVLGWFYLSVLPGWLG
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEQTTIDTSPWQIAKSVLIFLGIPLLAGFLSRFFGERAKDRDWYDNKFIPKISPWALYGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
LFTIVVLFSMQGEQITSQPWDVVRIALPLLAYFALMWGGGYVLGAAIGLGYERTTTLAFT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEE
AAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALRKRFTPTDGKVS
ECCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AP
CC
>Mature Secondary Structure 
SAPSSTEHPEVVGKLSTLDRYLAVWIGVAMVVGLLVGRWIPGVNTALDKVQIDGISLPI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCHHH
ALGLLIMMYPVLAKVRYDRLDTVTGDKKLLAGSLFLNWVLGPALMFALAWLFLPDLPEYR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TGLIIVGIARCIAMVIIWNDLACGDREAAAVLVAINSVFQVIMFAVLGWFYLSVLPGWLG
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEQTTIDTSPWQIAKSVLIFLGIPLLAGFLSRFFGERAKDRDWYDNKFIPKISPWALYGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
LFTIVVLFSMQGEQITSQPWDVVRIALPLLAYFALMWGGGYVLGAAIGLGYERTTTLAFT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEE
AAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALRKRFTPTDGKVS
ECCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]