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The map label for this gene is arsR [C]

Identifier: 77454725

GI number: 77454725

Start: 153953

End: 154321

Strand: Direct

Name: arsR [C]

Synonym: pREL1_0158

Alternate gene names: 77454725

Gene position: 153953-154321 (Clockwise)

Preceding gene: 77454724

Following gene: 77454726

Centisome position: 56.69

GC content: 63.69

Gene sequence:

>369_bases
GTGGCGGAGACCGGCGCCTGTTGTTCGCCACTCAACCGTGAACCGTTGACCGAAGACTGGGCTGGTGATCTGGCCCGGAT
GTTCAAAGCGCTCGGCGATCCCGTCCGGCTGCGACTGCTGAGCCTGGTGGCCAGCCACGAGGGCGGTGAAGCCTGCGTCT
GCGACATCTCCGACACCTTCGACTTGTCCCAGCCGACGATTTCGCATCACCTCAAGGTGTTGCGCCAGGCCGGACTCCTC
GACTGCGAACGTCGCGGGACCTGGGTGTACTACTGGGTGATACCCGCAGCCCTGCAACAACTTTCCGCCGTTCTGCTCGT
GGAAGCATCATCCACTGCCGCCGACGTCCCACAGGAGACCGCCGTATGA

Upstream 100 bases:

>100_bases
GTCCAGGGAAGGGGCCTTCCCGTGCTGCAGAACCAGAGGCGTGCCCCATGTTGCGAACTGATTTGATCGATGTCAATATT
GATGTATGTCGAATCAAGAT

Downstream 100 bases:

>100_bases
GCGCCCCGTCCAGTACCGAACACCCCGAAGTCGTCGGAAAACTCTCCACCCTCGACCGCTATCTGGCGGTCTGGATCGGC
GTGGCCATGGTCGTCGGCCT

Product: putative arsenical resistance operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MAETGACCSPLNREPLTEDWAGDLARMFKALGDPVRLRLLSLVASHEGGEACVCDISDTFDLSQPTISHHLKVLRQAGLL
DCERRGTWVYYWVIPAALQQLSAVLLVEASSTAADVPQETAV

Sequences:

>Translated_122_residues
MAETGACCSPLNREPLTEDWAGDLARMFKALGDPVRLRLLSLVASHEGGEACVCDISDTFDLSQPTISHHLKVLRQAGLL
DCERRGTWVYYWVIPAALQQLSAVLLVEASSTAADVPQETAV
>Mature_121_residues
AETGACCSPLNREPLTEDWAGDLARMFKALGDPVRLRLLSLVASHEGGEACVCDISDTFDLSQPTISHHLKVLRQAGLLD
CERRGTWVYYWVIPAALQQLSAVLLVEASSTAADVPQETAV

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=70, Percent_Identity=45.7142857142857, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13239; Mature: 13108

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETGACCSPLNREPLTEDWAGDLARMFKALGDPVRLRLLSLVASHEGGEACVCDISDTF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
DLSQPTISHHLKVLRQAGLLDCERRGTWVYYWVIPAALQQLSAVLLVEASSTAADVPQET
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHEEECCCCCCCCCCCC
AV
CC
>Mature Secondary Structure 
AETGACCSPLNREPLTEDWAGDLARMFKALGDPVRLRLLSLVASHEGGEACVCDISDTF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
DLSQPTISHHLKVLRQAGLLDCERRGTWVYYWVIPAALQQLSAVLLVEASSTAADVPQET
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHEEECCCCCCCCCCCC
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]