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The map label for this gene is arsC2 [H]

Identifier: 77454723

GI number: 77454723

Start: 152879

End: 153550

Strand: Direct

Name: arsC2 [H]

Synonym: pREL1_0156

Alternate gene names: 77454723

Gene position: 152879-153550 (Clockwise)

Preceding gene: 77454722

Following gene: 77454724

Centisome position: 56.29

GC content: 62.35

Gene sequence:

>672_bases
ATGACCGACAACCTCAGCACCACAACACATCACCGCGACGACCTGACCATCGATCAACGGTTAGCCCTCAAAAGCGCCGC
CGCACACCTGGCCACGGAATTCACCGACGTCTTCAACACCGAAACCATCGAGCGGTTCCTGCATTCGTCCTACGACCAGT
TCGCCGGCCGCGCCTCCGTCGTCAACTACCTCCCTCTCCTGGCCGAACGCTTCGCCCGGCAGCGACTACGCGCCCTGGCC
AAGGTCGAAGGACTCTCCAACGACGGCAAACCCACCGTGTTGTTCTTGTGCACGCACAACGCCGGACGCTCCCAGATGGC
CATGGGATTCTTCGAAAAACTCGCCGGGGAACGTGCCGTCGCATGGTCCGGCGGATCCGAACCCGGCACCAGCGTCAACG
AAGCAGCCATCGAAGCAATGGCCGAACGTGGCATCGACATCAGCGGTGAATACCCCAAGCCATGGACTGACGAAGTGGTC
CGCGCAGCCGACGTCGTCATCACGATGGGCTGCGGAGATGCATGCCCGATCTTCCCCGGACGCCGCTACGAAGAATGGGT
CCTTCCCGACCCCGCAGGTCTCGGAGTCGACGCGATCCGCCCGATCCGTGACGAGATCGAACGGCGAGTACTCACATTGC
TCGACGAGATCGACATCGCCGCCCAGCACTGA

Upstream 100 bases:

>100_bases
CCCGCACCGGCAGTGCCGCAGCGTTCGACCGAGCCTTCGACGACATCGACCACCGAGTCGCTCGACTCGCCCCCCATTGC
CTCCCGAACGGAGAACTCTC

Downstream 100 bases:

>100_bases
TGCTCGTCGATGAATTCCTTGCGAAGAAGGTCTCTCATGTTCATTCCGGCAGTGGTCACCGCTTTTGTGCACTGGCTTCG
CAGCGGCTACCCGCAGGACG

Product: putative arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase 2; Arsenical pump modifier 2; Low molecular weight protein-tyrosine-phosphatase 2 [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTDNLSTTTHHRDDLTIDQRLALKSAAAHLATEFTDVFNTETIERFLHSSYDQFAGRASVVNYLPLLAERFARQRLRALA
KVEGLSNDGKPTVLFLCTHNAGRSQMAMGFFEKLAGERAVAWSGGSEPGTSVNEAAIEAMAERGIDISGEYPKPWTDEVV
RAADVVITMGCGDACPIFPGRRYEEWVLPDPAGLGVDAIRPIRDEIERRVLTLLDEIDIAAQH

Sequences:

>Translated_223_residues
MTDNLSTTTHHRDDLTIDQRLALKSAAAHLATEFTDVFNTETIERFLHSSYDQFAGRASVVNYLPLLAERFARQRLRALA
KVEGLSNDGKPTVLFLCTHNAGRSQMAMGFFEKLAGERAVAWSGGSEPGTSVNEAAIEAMAERGIDISGEYPKPWTDEVV
RAADVVITMGCGDACPIFPGRRYEEWVLPDPAGLGVDAIRPIRDEIERRVLTLLDEIDIAAQH
>Mature_222_residues
TDNLSTTTHHRDDLTIDQRLALKSAAAHLATEFTDVFNTETIERFLHSSYDQFAGRASVVNYLPLLAERFARQRLRALAK
VEGLSNDGKPTVLFLCTHNAGRSQMAMGFFEKLAGERAVAWSGGSEPGTSVNEAAIEAMAERGIDISGEYPKPWTDEVVR
AADVVITMGCGDACPIFPGRRYEEWVLPDPAGLGVDAIRPIRDEIERRVLTLLDEIDIAAQH

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 24572; Mature: 24441

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNLSTTTHHRDDLTIDQRLALKSAAAHLATEFTDVFNTETIERFLHSSYDQFAGRASV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VNYLPLLAERFARQRLRALAKVEGLSNDGKPTVLFLCTHNAGRSQMAMGFFEKLAGERAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEE
AWSGGSEPGTSVNEAAIEAMAERGIDISGEYPKPWTDEVVRAADVVITMGCGDACPIFPG
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCC
RRYEEWVLPDPAGLGVDAIRPIRDEIERRVLTLLDEIDIAAQH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDNLSTTTHHRDDLTIDQRLALKSAAAHLATEFTDVFNTETIERFLHSSYDQFAGRASV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VNYLPLLAERFARQRLRALAKVEGLSNDGKPTVLFLCTHNAGRSQMAMGFFEKLAGERAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEE
AWSGGSEPGTSVNEAAIEAMAERGIDISGEYPKPWTDEVVRAADVVITMGCGDACPIFPG
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCC
RRYEEWVLPDPAGLGVDAIRPIRDEIERRVLTLLDEIDIAAQH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA