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The map label for this gene is ctaD [H]

Identifier: 77454689

GI number: 77454689

Start: 120336

End: 122087

Strand: Direct

Name: ctaD [H]

Synonym: pREL1_0122

Alternate gene names: 77454689

Gene position: 120336-122087 (Clockwise)

Preceding gene: 77454688

Following gene: 77454690

Centisome position: 44.31

GC content: 59.99

Gene sequence:

>1752_bases
ATGACCGCAATTGCATCACCCCCCATCGCCGCCCGGCCGTACCCCGCGCGACGGGCGCCGAAGGGATCGGTGCTGCGGAA
CCTTGTGACGACGACCGATCACAAGACGCTCGGCTTGATGTATTTGGTGACTTCGTTCGCGTTCTTCCTCATCGGCGGGC
TCATGGCGCTGATCATGCGCAGCGAACTGGCGATTCCGGGCATGCAATTCCTGTCGAACGAGCAGTACAACCAGTTGTTC
ACCATGCACGGCACGATCATGCTGCTGCTGTACGCGACGCCGGTGGTGTTCGGATTCGCCAATTTCGTTCTCCCCCTGCA
GATCGGTGCGCCGGATGTCGCCTTCCCGCGACTGAACGCGTTCAGCTACTGGCTCTACCTTTTCGGTGCGCTCATCGCTA
CGGGCGGCTTCGTCACTCCCGGCGGTGCCGCAGATTTCGGCTGGACGGCCTACACACCTCTGAGTTCGGCAGTCAGCTCA
CCTGGGGTCGGTGCGGATCTGTGGATTGTGGGGCTTCTCGTCTCCGGTCTCGGCACCATTCTCGGCGCGGTCAACATGAT
CACCACCATTGTCTGCTTACGCGCTCCGGGGATGACGATGTTCCGCATGCCGATCTTCACGTGGAACATCTTCATCACCT
CGGTCTTGATTCTGTTGGCCTTCCCGCTGTTGACCGCGGCACTCTTCGCACTGCTTTACGACCGTCGCCTCGGTGGCAAC
ATCTTCGACCCCGCGAATGGCGGAGTCCTGCTGTGGCAGCACCTGTTCTGGTTCTTCGGTCATCCCGAGGTCTACATCAT
CGCGCTGCCGTTCTTCGGTATCGTCTCGGAGATATTTCCGGTCTTCAGCCGCAAACCGATCTTCGGCTACAGCGGCCTGG
TCTACGCGACGCTCGGTATCGCGGCGCTGTCGATCGCAGTGTGGGCGCATCACATGTACGCGACGGGCGCGGTCCTGCTG
CCGTACTTCTCGTTCATGACGTTCCTGATCGCCGTGCCGACGGGTGTGAAGATCTTCAACTGGATCGGAACGATGTGGAA
GGGGCACTTGACGTTCGAGTCACCGATGCTGTTCTCTCTCGGATTCTTGATCACCTTCCTCTTCGGTGGCCTGTCCGGTG
TGCTGCTGGCGAGCCCTCCGCTGGATTTTCAGGTCACGGATACTTACTTCGTTGTCGCCCATTTCCACTATGTGGTTTTC
GGTACGGTCGTGTTCGCGACGTACGCCGGTATCTATTTCTGGTTCCCGAAGATGACCGGTCGCATGATGGACGAACGCCT
GGGCAAGTGGCACTTCTGGACCACGTTCGTCGGCTTTCACATGACGTTCCTCGTCCAGCACTGGCTCGGTGCCGAAGGTA
TGCCCCGTCGTTACGCCGACTACCTACCCGCGGATGGATTCACCACCCTCAATACAGTCTCGACCATCGGATCCTTCATT
CTCGGAGCCTCCACTCTCCCGTTCATCTGGAACGTCTTCAAGAGCTACAGATTCGGCGAAGTGGTCACCGTCGACGATCC
GTGGGGCTACGGAAACTCGCTGGAGTGGGCGACCACTTGCCCGCCGCCGCGGCACAACTTCACGGAGTTGCCGCGCATTC
GTAGCGAGCGTCCGGCCTTCGAGTTGCACTACCCGCACATGGTGGCTCGGATGCGGGCAGAAGCACACGTCGGGGTCGGT
CATCGGCCGGAGACGACCTCAGAATCGGAGAAGGTACTTACCGGCATGCCCGACGATGACGAGAAGAAGTAG

Upstream 100 bases:

>100_bases
ACTCGATCGGTACCTCGAACCCAAAAACTATGCAACGTAGTATTTGGGTTATGCTTCTGTCGCACACTCTATTTGCGTCT
CGACAGGAAGCGGGCTGACC

Downstream 100 bases:

>100_bases
TTCGGCGACGAAGTCCGATGGGAAAGCCAATGTCAACACGAACAATGCCAGTGGTCATCGTCCCGGCAACAGATGCCGCT
GCCGCCCTACTGACGGACTG

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-alpha; Cytochrome c oxidase polypeptide I-alpha [H]

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MTAIASPPIAARPYPARRAPKGSVLRNLVTTTDHKTLGLMYLVTSFAFFLIGGLMALIMRSELAIPGMQFLSNEQYNQLF
TMHGTIMLLLYATPVVFGFANFVLPLQIGAPDVAFPRLNAFSYWLYLFGALIATGGFVTPGGAADFGWTAYTPLSSAVSS
PGVGADLWIVGLLVSGLGTILGAVNMITTIVCLRAPGMTMFRMPIFTWNIFITSVLILLAFPLLTAALFALLYDRRLGGN
IFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYSGLVYATLGIAALSIAVWAHHMYATGAVLL
PYFSFMTFLIAVPTGVKIFNWIGTMWKGHLTFESPMLFSLGFLITFLFGGLSGVLLASPPLDFQVTDTYFVVAHFHYVVF
GTVVFATYAGIYFWFPKMTGRMMDERLGKWHFWTTFVGFHMTFLVQHWLGAEGMPRRYADYLPADGFTTLNTVSTIGSFI
LGASTLPFIWNVFKSYRFGEVVTVDDPWGYGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVARMRAEAHVGVG
HRPETTSESEKVLTGMPDDDEKK

Sequences:

>Translated_583_residues
MTAIASPPIAARPYPARRAPKGSVLRNLVTTTDHKTLGLMYLVTSFAFFLIGGLMALIMRSELAIPGMQFLSNEQYNQLF
TMHGTIMLLLYATPVVFGFANFVLPLQIGAPDVAFPRLNAFSYWLYLFGALIATGGFVTPGGAADFGWTAYTPLSSAVSS
PGVGADLWIVGLLVSGLGTILGAVNMITTIVCLRAPGMTMFRMPIFTWNIFITSVLILLAFPLLTAALFALLYDRRLGGN
IFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYSGLVYATLGIAALSIAVWAHHMYATGAVLL
PYFSFMTFLIAVPTGVKIFNWIGTMWKGHLTFESPMLFSLGFLITFLFGGLSGVLLASPPLDFQVTDTYFVVAHFHYVVF
GTVVFATYAGIYFWFPKMTGRMMDERLGKWHFWTTFVGFHMTFLVQHWLGAEGMPRRYADYLPADGFTTLNTVSTIGSFI
LGASTLPFIWNVFKSYRFGEVVTVDDPWGYGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVARMRAEAHVGVG
HRPETTSESEKVLTGMPDDDEKK
>Mature_582_residues
TAIASPPIAARPYPARRAPKGSVLRNLVTTTDHKTLGLMYLVTSFAFFLIGGLMALIMRSELAIPGMQFLSNEQYNQLFT
MHGTIMLLLYATPVVFGFANFVLPLQIGAPDVAFPRLNAFSYWLYLFGALIATGGFVTPGGAADFGWTAYTPLSSAVSSP
GVGADLWIVGLLVSGLGTILGAVNMITTIVCLRAPGMTMFRMPIFTWNIFITSVLILLAFPLLTAALFALLYDRRLGGNI
FDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYSGLVYATLGIAALSIAVWAHHMYATGAVLLP
YFSFMTFLIAVPTGVKIFNWIGTMWKGHLTFESPMLFSLGFLITFLFGGLSGVLLASPPLDFQVTDTYFVVAHFHYVVFG
TVVFATYAGIYFWFPKMTGRMMDERLGKWHFWTTFVGFHMTFLVQHWLGAEGMPRRYADYLPADGFTTLNTVSTIGSFIL
GASTLPFIWNVFKSYRFGEVVTVDDPWGYGNSLEWATTCPPPRHNFTELPRIRSERPAFELHYPHMVARMRAEAHVGVGH
RPETTSESEKVLTGMPDDDEKK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=43.4697855750487, Blast_Score=382, Evalue=1e-106,
Organism=Escherichia coli, GI1786634, Length=547, Percent_Identity=41.4990859232175, Blast_Score=408, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=38.9830508474576, Blast_Score=355, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=41.5094339622642, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=38.1147540983607, Blast_Score=149, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 64789; Mature: 64657

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIASPPIAARPYPARRAPKGSVLRNLVTTTDHKTLGLMYLVTSFAFFLIGGLMALIMR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SELAIPGMQFLSNEQYNQLFTMHGTIMLLLYATPVVFGFANFVLPLQIGAPDVAFPRLNA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHH
FSYWLYLFGALIATGGFVTPGGAADFGWTAYTPLSSAVSSPGVGADLWIVGLLVSGLGTI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGAVNMITTIVCLRAPGMTMFRMPIFTWNIFITSVLILLAFPLLTAALFALLYDRRLGGN
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYSGLVYATLGI
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AALSIAVWAHHMYATGAVLLPYFSFMTFLIAVPTGVKIFNWIGTMWKGHLTFESPMLFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCHHHHH
GFLITFLFGGLSGVLLASPPLDFQVTDTYFVVAHFHYVVFGTVVFATYAGIYFWFPKMTG
HHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMDERLGKWHFWTTFVGFHMTFLVQHWLGAEGMPRRYADYLPADGFTTLNTVSTIGSFI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
LGASTLPFIWNVFKSYRFGEVVTVDDPWGYGNSLEWATTCPPPRHNFTELPRIRSERPAF
HCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCE
ELHYPHMVARMRAEAHVGVGHRPETTSESEKVLTGMPDDDEKK
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
TAIASPPIAARPYPARRAPKGSVLRNLVTTTDHKTLGLMYLVTSFAFFLIGGLMALIMR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SELAIPGMQFLSNEQYNQLFTMHGTIMLLLYATPVVFGFANFVLPLQIGAPDVAFPRLNA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHH
FSYWLYLFGALIATGGFVTPGGAADFGWTAYTPLSSAVSSPGVGADLWIVGLLVSGLGTI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGAVNMITTIVCLRAPGMTMFRMPIFTWNIFITSVLILLAFPLLTAALFALLYDRRLGGN
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYSGLVYATLGI
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AALSIAVWAHHMYATGAVLLPYFSFMTFLIAVPTGVKIFNWIGTMWKGHLTFESPMLFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCHHHHH
GFLITFLFGGLSGVLLASPPLDFQVTDTYFVVAHFHYVVFGTVVFATYAGIYFWFPKMTG
HHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMDERLGKWHFWTTFVGFHMTFLVQHWLGAEGMPRRYADYLPADGFTTLNTVSTIGSFI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
LGASTLPFIWNVFKSYRFGEVVTVDDPWGYGNSLEWATTCPPPRHNFTELPRIRSERPAF
HCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCE
ELHYPHMVARMRAEAHVGVGHRPETTSESEKVLTGMPDDDEKK
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA