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The map label for this gene is gpmA [H]

Identifier: 75674401

GI number: 75674401

Start: 232780

End: 233403

Strand: Direct

Name: gpmA [H]

Synonym: Nwi_0202

Alternate gene names: 75674401

Gene position: 232780-233403 (Clockwise)

Preceding gene: 75674400

Following gene: 75674404

Centisome position: 6.84

GC content: 62.5

Gene sequence:

>624_bases
ATGAGCGAACGTCTTCTGGTGCTCGTGCGTCACGGCCAGAGCGAATGGAATCTGAAAAACCTGTTCACAGGCTGGAAGGA
TCCGGATCTGACGGAGTTGGGCGCGGCTGAGGCGAAGGATGCGGGGCGCAAGCTGAAGGCGCAGGGCTTTGTTTTCGACA
TCGCCTTCACCTCGACGTTGATCCGTGCCCAGCACACGCTCGATCTTGTGCTCAAGGAACTGGACCAGACCGGGATTCCG
GTCAGGAAAGACCAGGCGCTGAACGAGCGTGACTATGGCGATCTTTCGGGCCTCAACAAGGATGAGGCCCGCAAGAAGTG
GGGCGACGAACAGGTGCTGGTGTGGCGCCGGTCGTATGACGTACCGCCGCCCGGCGGCGAGAGCCTGAAGGATACGCTGG
CGCGCACGCTGCCGTACTTCGTGCAGGAAATCCTGCCATGCGTTCTTCGCGGCGAGTGCACGCTCGTGGCGGCGCACGGC
AACTCGCTGCGCGCGCTCGTCATGGTTCTGGAAAAACTGTCGCCGGAACAGATTCTCGCGCGCGAACTGGCGACCGGCGC
GCCCGTGATCTATCGGCTCAACGCCGATGCGACGGTGGCATCGAAACTGGATCTCGCGGCCTGA

Upstream 100 bases:

>100_bases
TTTCGTGCGAAGACGCCGCGTCAAATCAAGATCCGAGAGCCACGCTTTTGATCCGTCGGAAGCGGAAAGGCTCCAGGGAT
CCAAGAATGGAGCAGGCAGA

Downstream 100 bases:

>100_bases
CGAACCTCATTCCAGGCCAATCCGCCCGGCCTCCCACCCCAGCATCGCGTGCTTGCGGGTGATTCCCCAGTGATACCCCG
TCAGCGCGCCGCTTTTGCCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTLIRAQHTLDLVLKELDQTGIP
VRKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYDVPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHG
NSLRALVMVLEKLSPEQILARELATGAPVIYRLNADATVASKLDLAA

Sequences:

>Translated_207_residues
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTLIRAQHTLDLVLKELDQTGIP
VRKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYDVPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHG
NSLRALVMVLEKLSPEQILARELATGAPVIYRLNADATVASKLDLAA
>Mature_206_residues
SERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTLIRAQHTLDLVLKELDQTGIPV
RKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYDVPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHGN
SLRALVMVLEKLSPEQILARELATGAPVIYRLNADATVASKLDLAA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=223, Percent_Identity=46.1883408071749, Blast_Score=185, Evalue=3e-47,
Organism=Homo sapiens, GI50593010, Length=223, Percent_Identity=43.4977578475336, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI4502445, Length=225, Percent_Identity=41.7777777777778, Blast_Score=171, Evalue=3e-43,
Organism=Homo sapiens, GI40353764, Length=225, Percent_Identity=41.7777777777778, Blast_Score=171, Evalue=3e-43,
Organism=Homo sapiens, GI71274132, Length=223, Percent_Identity=43.0493273542601, Blast_Score=170, Evalue=8e-43,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=46.6666666666667, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1786970, Length=221, Percent_Identity=47.5113122171946, Blast_Score=194, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6322697, Length=216, Percent_Identity=42.1296296296296, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324516, Length=264, Percent_Identity=26.8939393939394, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320183, Length=268, Percent_Identity=25.3731343283582, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324857, Length=179, Percent_Identity=30.1675977653631, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646216, Length=217, Percent_Identity=45.6221198156682, Blast_Score=180, Evalue=5e-46,
Organism=Drosophila melanogaster, GI85725270, Length=219, Percent_Identity=44.7488584474886, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI85725272, Length=219, Percent_Identity=44.7488584474886, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24650981, Length=219, Percent_Identity=44.7488584474886, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=32.7188940092166, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=32.7188940092166, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=32.7188940092166, Blast_Score=118, Evalue=3e-27,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22977; Mature: 22845

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTL
CCCCEEEEEECCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHCCEEECCCEEEEHHHHHHH
IRAQHTLDLVLKELDQTGIPVRKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCC
VPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHGNSLRALVMVLEKLSPEQILA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHH
RELATGAPVIYRLNADATVASKLDLAA
HHHHCCCCEEEEECCCCHHHHHCCCCC
>Mature Secondary Structure 
SERLLVLVRHGQSEWNLKNLFTGWKDPDLTELGAAEAKDAGRKLKAQGFVFDIAFTSTL
CCCEEEEEECCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHCCEEECCCEEEEHHHHHHH
IRAQHTLDLVLKELDQTGIPVRKDQALNERDYGDLSGLNKDEARKKWGDEQVLVWRRSYD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCC
VPPPGGESLKDTLARTLPYFVQEILPCVLRGECTLVAAHGNSLRALVMVLEKLSPEQILA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHH
RELATGAPVIYRLNADATVASKLDLAA
HHHHCCCCEEEEECCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA