| Definition | Nitrobacter winogradskyi Nb-255, complete genome. |
|---|---|
| Accession | NC_007406 |
| Length | 3,402,093 |
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The map label for this gene is dnaJ [H]
Identifier: 75674397
GI number: 75674397
Start: 229185
End: 230321
Strand: Direct
Name: dnaJ [H]
Synonym: Nwi_0198
Alternate gene names: 75674397
Gene position: 229185-230321 (Clockwise)
Preceding gene: 75674396
Following gene: 75674398
Centisome position: 6.74
GC content: 62.53
Gene sequence:
>1137_bases ATGTCGACCAAACGCTGTTACTACGAAACCCTTGAGGTCGATCGGAACGCGGACGACACCAAACTCAAGGCAGCCTTTCG CAAGCTGGCCATGAAATGGCACCCGGACAGAAATCCGGGCGACTCGTCCAGCGAGATGCGCTTCAAGGAAATCAACGAGG CCTATGAGGTCCTGAAGGACAGCAACAAGCGCGCCGCTTACGACCGCTTCGGCCACGCGGCGTTCGAGCAGGGCGGCATG GGCGGCGGCGCGGCCGGGTTCGGCGCAGGCTTCGCTTCCTCATTCTCCGACATCTTCGAGGATCTGTTCGGCATGTCCGG GCAGCGCGGCCGGTCAGGCGGACGCGAACGAGGCGGAGATCTTCGATATAATATGGAGATCACGCTTGAGGAGGCTTATC ACGGCAAGACCGCCCAGATCGAGATTCCAGTCTCGGTAACGTGCGAGTCCTGCTCTGGGACGGGCGCCAAGGCCGGGACC AAGCCGAAGAACTGCGCGATGTGCGGGGGCGCCGGCCGGATTCGCCAGGCTCAGGGCTTCTTCACGCTGGAGCGCACCTG TCCCGGCTGTCAGGGACGGGGCCAGATGATCGAGGATCCCTGCCCGTCCTGTGGCGGGTCGGGCCGGGTCAACCGGGAGC GTTCGCTTTCGGTCAATATTCCCGCCGGCGTCGAGGATGGCACCCGCATTCGCCTCGCTGGCGAAGGTGAGGCGGGAGTC CGTGGCGGCCCGCCTGGCGACCTCTACATTTTCCTCTCGCTGATTCCGCATCAGTTCTTCCAGCGGGACGGCGCCGATCT GCATTGCCGTGTGCCGATTTCAATGGTCGCCGCCGCTCTTGGCGGAGAGATTGAGGTGCCGACCATCGACAAGGGCAAGA CCAAGGTGCGGGTGCCGTCGGGAACCCAGTCCGGCCGCCGTTTTCGCATTGCAACAAAGGGAATGCCCGTGCTGCGCTCT CGTCAGACCGGCGACATGTATGTTCAGGTGGTGGTGGAAACTCCGCAGAATCTGACCAAGCGACAACAGGATCTTTTGGC CGAGTTTGAAAAGCTGTCGTCGGGAGAGACTCAGCCGGAGGCGGCGGGTTTCTTCACTAAGGTCAAGGACTTCTTCGGCA CTCGGGCGACTCCGTAA
Upstream 100 bases:
>100_bases GGAGGGCGGGGTCATGTTTGTTTAAGCGGGATGCTTCATCCGGCGAGCGAATTTCTGGCTCGCCTTTCTGGATGAAGCGA CCTTCGGGCGGAACGGACTG
Downstream 100 bases:
>100_bases TCACCGTTTTGCTTGACCGGGCCGATCGTCGGATGTACCTGTGAATAACTTAAGCCTGCCTCCCTGCCAGTATTGACCCC ACCTGGGTGCGAAATGCCTT
Product: chaperone protein DnaJ
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 378; Mature: 377
Protein sequence:
>378_residues MSTKRCYYETLEVDRNADDTKLKAAFRKLAMKWHPDRNPGDSSSEMRFKEINEAYEVLKDSNKRAAYDRFGHAAFEQGGM GGGAAGFGAGFASSFSDIFEDLFGMSGQRGRSGGRERGGDLRYNMEITLEEAYHGKTAQIEIPVSVTCESCSGTGAKAGT KPKNCAMCGGAGRIRQAQGFFTLERTCPGCQGRGQMIEDPCPSCGGSGRVNRERSLSVNIPAGVEDGTRIRLAGEGEAGV RGGPPGDLYIFLSLIPHQFFQRDGADLHCRVPISMVAAALGGEIEVPTIDKGKTKVRVPSGTQSGRRFRIATKGMPVLRS RQTGDMYVQVVVETPQNLTKRQQDLLAEFEKLSSGETQPEAAGFFTKVKDFFGTRATP
Sequences:
>Translated_378_residues MSTKRCYYETLEVDRNADDTKLKAAFRKLAMKWHPDRNPGDSSSEMRFKEINEAYEVLKDSNKRAAYDRFGHAAFEQGGM GGGAAGFGAGFASSFSDIFEDLFGMSGQRGRSGGRERGGDLRYNMEITLEEAYHGKTAQIEIPVSVTCESCSGTGAKAGT KPKNCAMCGGAGRIRQAQGFFTLERTCPGCQGRGQMIEDPCPSCGGSGRVNRERSLSVNIPAGVEDGTRIRLAGEGEAGV RGGPPGDLYIFLSLIPHQFFQRDGADLHCRVPISMVAAALGGEIEVPTIDKGKTKVRVPSGTQSGRRFRIATKGMPVLRS RQTGDMYVQVVVETPQNLTKRQQDLLAEFEKLSSGETQPEAAGFFTKVKDFFGTRATP >Mature_377_residues STKRCYYETLEVDRNADDTKLKAAFRKLAMKWHPDRNPGDSSSEMRFKEINEAYEVLKDSNKRAAYDRFGHAAFEQGGMG GGAAGFGAGFASSFSDIFEDLFGMSGQRGRSGGRERGGDLRYNMEITLEEAYHGKTAQIEIPVSVTCESCSGTGAKAGTK PKNCAMCGGAGRIRQAQGFFTLERTCPGCQGRGQMIEDPCPSCGGSGRVNRERSLSVNIPAGVEDGTRIRLAGEGEAGVR GGPPGDLYIFLSLIPHQFFQRDGADLHCRVPISMVAAALGGEIEVPTIDKGKTKVRVPSGTQSGRRFRIATKGMPVLRSR QTGDMYVQVVVETPQNLTKRQQDLLAEFEKLSSGETQPEAAGFFTKVKDFFGTRATP
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain [H]
Homologues:
Organism=Homo sapiens, GI205360838, Length=356, Percent_Identity=33.7078651685393, Blast_Score=211, Evalue=9e-55, Organism=Homo sapiens, GI205360840, Length=356, Percent_Identity=33.7078651685393, Blast_Score=210, Evalue=1e-54, Organism=Homo sapiens, GI4504511, Length=347, Percent_Identity=34.2939481268012, Blast_Score=169, Evalue=5e-42, Organism=Homo sapiens, GI5031741, Length=391, Percent_Identity=32.7365728900256, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI194328760, Length=341, Percent_Identity=31.9648093841642, Blast_Score=162, Evalue=7e-40, Organism=Homo sapiens, GI194328758, Length=341, Percent_Identity=31.9648093841642, Blast_Score=161, Evalue=1e-39, Organism=Homo sapiens, GI7706495, Length=340, Percent_Identity=32.0588235294118, Blast_Score=146, Evalue=3e-35, Organism=Homo sapiens, GI194328762, Length=310, Percent_Identity=30.6451612903226, Blast_Score=132, Evalue=6e-31, Organism=Homo sapiens, GI6631085, Length=360, Percent_Identity=27.7777777777778, Blast_Score=111, Evalue=1e-24, Organism=Homo sapiens, GI201862587, Length=398, Percent_Identity=26.3819095477387, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI201862518, Length=398, Percent_Identity=26.3819095477387, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI56549115, Length=398, Percent_Identity=26.3819095477387, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI9558755, Length=114, Percent_Identity=43.859649122807, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI5453690, Length=390, Percent_Identity=23.8461538461538, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI39204547, Length=370, Percent_Identity=23.5135135135135, Blast_Score=92, Evalue=1e-18, Organism=Homo sapiens, GI47777312, Length=102, Percent_Identity=47.0588235294118, Blast_Score=92, Evalue=1e-18, Organism=Homo sapiens, GI27151736, Length=106, Percent_Identity=41.5094339622642, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI88501736, Length=106, Percent_Identity=41.5094339622642, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI23503241, Length=104, Percent_Identity=42.3076923076923, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI194306642, Length=105, Percent_Identity=43.8095238095238, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI194306640, Length=105, Percent_Identity=43.8095238095238, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI17388799, Length=104, Percent_Identity=44.2307692307692, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI4885495, Length=65, Percent_Identity=52.3076923076923, Blast_Score=77, Evalue=3e-14, Organism=Homo sapiens, GI21553335, Length=103, Percent_Identity=38.8349514563107, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI45504382, Length=64, Percent_Identity=45.3125, Blast_Score=72, Evalue=9e-13, Organism=Homo sapiens, GI29126218, Length=70, Percent_Identity=42.8571428571429, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI68077168, Length=117, Percent_Identity=37.6068376068376, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI68077166, Length=117, Percent_Identity=37.6068376068376, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI24308127, Length=79, Percent_Identity=43.0379746835443, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI72534740, Length=108, Percent_Identity=37.037037037037, Blast_Score=67, Evalue=3e-11, Organism=Escherichia coli, GI1786197, Length=373, Percent_Identity=53.887399463807, Blast_Score=385, Evalue=1e-108, Organism=Escherichia coli, GI1787235, Length=354, Percent_Identity=31.0734463276836, Blast_Score=155, Evalue=4e-39, Organism=Caenorhabditis elegans, GI17553098, Length=371, Percent_Identity=33.9622641509434, Blast_Score=185, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17553096, Length=371, Percent_Identity=33.9622641509434, Blast_Score=185, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17507263, Length=353, Percent_Identity=32.8611898016997, Blast_Score=143, Evalue=1e-34, Organism=Caenorhabditis elegans, GI212645553, Length=363, Percent_Identity=31.404958677686, Blast_Score=130, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17563890, Length=359, Percent_Identity=29.5264623955432, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17534355, Length=389, Percent_Identity=24.6786632390745, Blast_Score=108, Evalue=5e-24, Organism=Caenorhabditis elegans, GI115532378, Length=95, Percent_Identity=46.3157894736842, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17554644, Length=93, Percent_Identity=40.8602150537634, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17554874, Length=100, Percent_Identity=40, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI86563276, Length=105, Percent_Identity=40.9523809523809, Blast_Score=72, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17538236, Length=107, Percent_Identity=36.4485981308411, Blast_Score=68, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6324265, Length=353, Percent_Identity=33.4277620396601, Blast_Score=179, Evalue=6e-46, Organism=Saccharomyces cerevisiae, GI6321094, Length=378, Percent_Identity=32.8042328042328, Blast_Score=136, Evalue=6e-33, Organism=Saccharomyces cerevisiae, GI6323870, Length=357, Percent_Identity=30.812324929972, Blast_Score=133, Evalue=5e-32, Organism=Saccharomyces cerevisiae, GI6323119, Length=382, Percent_Identity=29.0575916230367, Blast_Score=131, Evalue=2e-31, Organism=Saccharomyces cerevisiae, GI6324252, Length=446, Percent_Identity=24.6636771300448, Blast_Score=85, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6323813, Length=124, Percent_Identity=42.741935483871, Blast_Score=76, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322194, Length=86, Percent_Identity=41.8604651162791, Blast_Score=73, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6324321, Length=74, Percent_Identity=41.8918918918919, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324103, Length=66, Percent_Identity=48.4848484848485, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6320888, Length=99, Percent_Identity=37.3737373737374, Blast_Score=64, Evalue=4e-11, Organism=Drosophila melanogaster, GI45552813, Length=370, Percent_Identity=32.4324324324324, Blast_Score=171, Evalue=1e-42, Organism=Drosophila melanogaster, GI45549272, Length=370, Percent_Identity=32.4324324324324, Blast_Score=171, Evalue=1e-42, Organism=Drosophila melanogaster, GI45552811, Length=370, Percent_Identity=32.1621621621622, Blast_Score=170, Evalue=1e-42, Organism=Drosophila melanogaster, GI24646562, Length=348, Percent_Identity=34.7701149425287, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI24646560, Length=348, Percent_Identity=34.7701149425287, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI24646558, Length=348, Percent_Identity=34.7701149425287, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI24646556, Length=348, Percent_Identity=34.7701149425287, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI21357547, Length=348, Percent_Identity=34.7701149425287, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI20129487, Length=341, Percent_Identity=34.0175953079179, Blast_Score=152, Evalue=5e-37, Organism=Drosophila melanogaster, GI24584014, Length=341, Percent_Identity=34.0175953079179, Blast_Score=152, Evalue=5e-37, Organism=Drosophila melanogaster, GI19920464, Length=356, Percent_Identity=30.3370786516854, Blast_Score=141, Evalue=7e-34, Organism=Drosophila melanogaster, GI85726398, Length=363, Percent_Identity=25.8953168044077, Blast_Score=113, Evalue=2e-25, Organism=Drosophila melanogaster, GI28574949, Length=361, Percent_Identity=23.8227146814404, Blast_Score=111, Evalue=9e-25, Organism=Drosophila melanogaster, GI24658562, Length=356, Percent_Identity=28.0898876404494, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24658555, Length=356, Percent_Identity=28.0898876404494, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI18858081, Length=356, Percent_Identity=26.9662921348315, Blast_Score=92, Evalue=7e-19, Organism=Drosophila melanogaster, GI24654066, Length=66, Percent_Identity=53.030303030303, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24654070, Length=66, Percent_Identity=53.030303030303, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24654068, Length=66, Percent_Identity=53.030303030303, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24654072, Length=66, Percent_Identity=53.030303030303, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24762799, Length=115, Percent_Identity=38.2608695652174, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI161077138, Length=63, Percent_Identity=53.968253968254, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=42.1875, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=42.1875, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=42.1875, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR018253 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 [H]
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]
EC number: NA
Molecular weight: Translated: 40959; Mature: 40827
Theoretical pI: Translated: 8.54; Mature: 8.54
Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 2.7 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 5.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTKRCYYETLEVDRNADDTKLKAAFRKLAMKWHPDRNPGDSSSEMRFKEINEAYEVLKD CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC SNKRAAYDRFGHAAFEQGGMGGGAAGFGAGFASSFSDIFEDLFGMSGQRGRSGGRERGGD CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC LRYNMEITLEEAYHGKTAQIEIPVSVTCESCSGTGAKAGTKPKNCAMCGGAGRIRQAQGF EEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC FTLERTCPGCQGRGQMIEDPCPSCGGSGRVNRERSLSVNIPAGVEDGTRIRLAGEGEAGV EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCC RGGPPGDLYIFLSLIPHQFFQRDGADLHCRVPISMVAAALGGEIEVPTIDKGKTKVRVPS CCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCEECCCCCCCCEEEEECC GTQSGRRFRIATKGMPVLRSRQTGDMYVQVVVETPQNLTKRQQDLLAEFEKLSSGETQPE CCCCCCEEEEEECCCCHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCH AAGFFTKVKDFFGTRATP HHHHHHHHHHHHCCCCCC >Mature Secondary Structure STKRCYYETLEVDRNADDTKLKAAFRKLAMKWHPDRNPGDSSSEMRFKEINEAYEVLKD CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC SNKRAAYDRFGHAAFEQGGMGGGAAGFGAGFASSFSDIFEDLFGMSGQRGRSGGRERGGD CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC LRYNMEITLEEAYHGKTAQIEIPVSVTCESCSGTGAKAGTKPKNCAMCGGAGRIRQAQGF EEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC FTLERTCPGCQGRGQMIEDPCPSCGGSGRVNRERSLSVNIPAGVEDGTRIRLAGEGEAGV EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCC RGGPPGDLYIFLSLIPHQFFQRDGADLHCRVPISMVAAALGGEIEVPTIDKGKTKVRVPS CCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCEECCCCCCCCEEEEECC GTQSGRRFRIATKGMPVLRSRQTGDMYVQVVVETPQNLTKRQQDLLAEFEKLSSGETQPE CCCCCCEEEEEECCCCHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCH AAGFFTKVKDFFGTRATP HHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA