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The map label for this gene is glcD [H]

Identifier: 73539480

GI number: 73539480

Start: 2485823

End: 2487250

Strand: Direct

Name: glcD [H]

Synonym: Reut_B5658

Alternate gene names: 73539480

Gene position: 2485823-2487250 (Clockwise)

Preceding gene: 73539478

Following gene: 73539481

Centisome position: 91.18

GC content: 62.04

Gene sequence:

>1428_bases
ATGTCGAACCACCACGTGAACCATCTCATCTCCATCGTCGGCCCGGCCAATGTATTGGTCGGCGAGGACGTCCAGTCCTT
CGCCACCGACTATCGAGGTGTTTTCCGTGGTCAGGCTCTGGCGGTCGTCAGGCCGGCGTCGACCGCGGAGGTAAGCGCTG
TCGTGGCGTACTGCAACCGGAATGACATTCCAGTGGTGCCGCAGGGCGGCAACACCTCGCTCCTGGGGGGCAGCGTGCCG
GATGCCAGCGGGACGGCGGTACTGCTGTCGCTGACCCGGCTCAATCAGGTGCGCTCCGTCGATTCACTGAACGCGACGAT
GGTGGTCGAGGCCGGCGTCACGCTCCACGCGGCTCGCGCCGCCGCCGAGAAGGCTGGGGCGCTGTTTCCGCTTCGCATTG
GCTCGGAAGGCAGTTGTCAGATCGGCGGCAATCTTTCTACCAATGCCGGCGGTACGGCAGTGCTTCGGTACGGCAACATG
CGCGACCTCGTCCTGGGCCTGGAGGTTGTGCTGCCGAATGGCGAGATCTGGAACGGCCTGAGAGCGCTGAGGAAGGACAA
CGCTGGCTATGACCTGAAGCACCTCTTCATCGGCGCCGAGGGCACACTCGGAATCATCACCGCAGCCGTTCTGAAGATGT
ACCCGATTCCTCGCGCCAAATGCGTCGCGATGCTCGGTTCAGGGAGCGCCGACCACGCGCTTGAAGCATTCGGTCTGTTG
CGTCAGCGTCTTGGCACGGACGTCACGGCATTCGAACTGATCTCGTCGGACGCAATGACGTTGGTCCTCGGGCATCTGGG
CCGTCAGACATCGCCGCTTCCGACCACTCATCCCTGGTATGTCCTCGTGGAGATGTCGTCGACCTCGTCCCAGGAGATGG
GTGAAGCCGCTTTCTATTCAGCGTTGGGCGAGTTGGCCGACAAGGGCATGATCGACGATGCCGTCATCGCGTCCAACGAA
AAGCAGGCTACCGATTTCTGGCTTGTCCGCGAGGAGATATCGGATGCGCAGACCCGTGCACGTGGCAGCGTGCGATGCGA
TATTTCGGTGCCGCTGTCCAGTATTCCAAGATTCATCCGCGAGACCTCGGCCAAGGTGATGGCCGTCGCGCCTGCGACCC
GCATGGTGATCTATGGGCACGTTGGTGACGGCAATGTCCACTTCAATCCTCTACGGCCCGCCGACATGGCCGCCGAGGAT
TACCTCACCCGACACGGCGAAGCGATCACGAAGCTTGTCGATGACGCCGCGATGGCGCTGAACGGATCCATCTCCGCGGA
GCATGGCATCGGGGCCGCCAAGTGCGACGCACTGCTACACGTACGAAGCCAGGTGGAATTGAAGCTTGCATGGCGCGTCA
AACGTGCGCTTGACCCTGCCAACCTGATGAATCCCGGGAAAGTACTTCCTCTTATGCCCGCCGACTGA

Upstream 100 bases:

>100_bases
TATGCGGACGGCATGACGGCCCATATGCTTCGGACTGTGTCGGACGACTCAATGCAGATCCTTCCGGCGTCACGAGAACC
CTCTCACCGTCGGAGCCCGC

Downstream 100 bases:

>100_bases
GCGGCCACGCTGCAATGGAGACCCCTTGCACTGACGACATTCCTGGTATCGCACCGGCCCTGGAGCACACCAGTGCGGAC
GCGGATACCCTGATGCAGAT

Product: FAD linked oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSNHHVNHLISIVGPANVLVGEDVQSFATDYRGVFRGQALAVVRPASTAEVSAVVAYCNRNDIPVVPQGGNTSLLGGSVP
DASGTAVLLSLTRLNQVRSVDSLNATMVVEAGVTLHAARAAAEKAGALFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNM
RDLVLGLEVVLPNGEIWNGLRALRKDNAGYDLKHLFIGAEGTLGIITAAVLKMYPIPRAKCVAMLGSGSADHALEAFGLL
RQRLGTDVTAFELISSDAMTLVLGHLGRQTSPLPTTHPWYVLVEMSSTSSQEMGEAAFYSALGELADKGMIDDAVIASNE
KQATDFWLVREEISDAQTRARGSVRCDISVPLSSIPRFIRETSAKVMAVAPATRMVIYGHVGDGNVHFNPLRPADMAAED
YLTRHGEAITKLVDDAAMALNGSISAEHGIGAAKCDALLHVRSQVELKLAWRVKRALDPANLMNPGKVLPLMPAD

Sequences:

>Translated_475_residues
MSNHHVNHLISIVGPANVLVGEDVQSFATDYRGVFRGQALAVVRPASTAEVSAVVAYCNRNDIPVVPQGGNTSLLGGSVP
DASGTAVLLSLTRLNQVRSVDSLNATMVVEAGVTLHAARAAAEKAGALFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNM
RDLVLGLEVVLPNGEIWNGLRALRKDNAGYDLKHLFIGAEGTLGIITAAVLKMYPIPRAKCVAMLGSGSADHALEAFGLL
RQRLGTDVTAFELISSDAMTLVLGHLGRQTSPLPTTHPWYVLVEMSSTSSQEMGEAAFYSALGELADKGMIDDAVIASNE
KQATDFWLVREEISDAQTRARGSVRCDISVPLSSIPRFIRETSAKVMAVAPATRMVIYGHVGDGNVHFNPLRPADMAAED
YLTRHGEAITKLVDDAAMALNGSISAEHGIGAAKCDALLHVRSQVELKLAWRVKRALDPANLMNPGKVLPLMPAD
>Mature_474_residues
SNHHVNHLISIVGPANVLVGEDVQSFATDYRGVFRGQALAVVRPASTAEVSAVVAYCNRNDIPVVPQGGNTSLLGGSVPD
ASGTAVLLSLTRLNQVRSVDSLNATMVVEAGVTLHAARAAAEKAGALFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNMR
DLVLGLEVVLPNGEIWNGLRALRKDNAGYDLKHLFIGAEGTLGIITAAVLKMYPIPRAKCVAMLGSGSADHALEAFGLLR
QRLGTDVTAFELISSDAMTLVLGHLGRQTSPLPTTHPWYVLVEMSSTSSQEMGEAAFYSALGELADKGMIDDAVIASNEK
QATDFWLVREEISDAQTRARGSVRCDISVPLSSIPRFIRETSAKVMAVAPATRMVIYGHVGDGNVHFNPLRPADMAAEDY
LTRHGEAITKLVDDAAMALNGSISAEHGIGAAKCDALLHVRSQVELKLAWRVKRALDPANLMNPGKVLPLMPAD

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=453, Percent_Identity=37.0860927152318, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI37595756, Length=435, Percent_Identity=32.6436781609195, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI37595754, Length=458, Percent_Identity=31.0043668122271, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4501993, Length=463, Percent_Identity=23.9740820734341, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789351, Length=459, Percent_Identity=28.5403050108932, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787977, Length=521, Percent_Identity=24.5681381957774, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI48994907, Length=218, Percent_Identity=29.3577981651376, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534361, Length=454, Percent_Identity=34.5814977973568, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71992373, Length=471, Percent_Identity=30.3609341825902, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992381, Length=471, Percent_Identity=30.3609341825902, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71992392, Length=370, Percent_Identity=30.8108108108108, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17556096, Length=181, Percent_Identity=29.2817679558011, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320023, Length=479, Percent_Identity=35.2818371607516, Blast_Score=314, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6320764, Length=455, Percent_Identity=34.5054945054945, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320027, Length=446, Percent_Identity=28.2511210762332, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI18921117, Length=472, Percent_Identity=36.228813559322, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24639277, Length=472, Percent_Identity=36.228813559322, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24639275, Length=472, Percent_Identity=36.228813559322, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24653753, Length=199, Percent_Identity=29.1457286432161, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50257; Mature: 50126

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHHVNHLISIVGPANVLVGEDVQSFATDYRGVFRGQALAVVRPASTAEVSAVVAYCNR
CCCCCHHHHHEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHEEEEEEECC
NDIPVVPQGGNTSLLGGSVPDASGTAVLLSLTRLNQVRSVDSLNATMVVEAGVTLHAARA
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCEEHHHHH
AAEKAGALFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNMRDLVLGLEVVLPNGEIWNGL
HHHHCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCHHHEEEEEEEEECCCHHHHHH
RALRKDNAGYDLKHLFIGAEGTLGIITAAVLKMYPIPRAKCVAMLGSGSADHALEAFGLL
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHEECCCCHHHHHHHHHHH
RQRLGTDVTAFELISSDAMTLVLGHLGRQTSPLPTTHPWYVLVEMSSTSSQEMGEAAFYS
HHHHCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
ALGELADKGMIDDAVIASNEKQATDFWLVREEISDAQTRARGSVRCDISVPLSSIPRFIR
HHHHHHHCCCCCCHHEECCCCCCCHHEEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHH
ETSAKVMAVAPATRMVIYGHVGDGNVHFNPLRPADMAAEDYLTRHGEAITKLVDDAAMAL
HCCCCEEEECCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGSISAEHGIGAAKCDALLHVRSQVELKLAWRVKRALDPANLMNPGKVLPLMPAD
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHCCCHHCCCCCCEEECCCCC
>Mature Secondary Structure 
SNHHVNHLISIVGPANVLVGEDVQSFATDYRGVFRGQALAVVRPASTAEVSAVVAYCNR
CCCCHHHHHEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHEEEEEEECC
NDIPVVPQGGNTSLLGGSVPDASGTAVLLSLTRLNQVRSVDSLNATMVVEAGVTLHAARA
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCEEHHHHH
AAEKAGALFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNMRDLVLGLEVVLPNGEIWNGL
HHHHCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCHHHEEEEEEEEECCCHHHHHH
RALRKDNAGYDLKHLFIGAEGTLGIITAAVLKMYPIPRAKCVAMLGSGSADHALEAFGLL
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHEECCCCHHHHHHHHHHH
RQRLGTDVTAFELISSDAMTLVLGHLGRQTSPLPTTHPWYVLVEMSSTSSQEMGEAAFYS
HHHHCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
ALGELADKGMIDDAVIASNEKQATDFWLVREEISDAQTRARGSVRCDISVPLSSIPRFIR
HHHHHHHCCCCCCHHEECCCCCCCHHEEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHH
ETSAKVMAVAPATRMVIYGHVGDGNVHFNPLRPADMAAEDYLTRHGEAITKLVDDAAMAL
HCCCCEEEECCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGSISAEHGIGAAKCDALLHVRSQVELKLAWRVKRALDPANLMNPGKVLPLMPAD
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHCCCHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]