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The map label for this gene is cheW [H]

Identifier: 73539431

GI number: 73539431

Start: 2429250

End: 2429744

Strand: Direct

Name: cheW [H]

Synonym: Reut_B5609

Alternate gene names: 73539431

Gene position: 2429250-2429744 (Clockwise)

Preceding gene: 73539430

Following gene: 73539432

Centisome position: 89.11

GC content: 64.65

Gene sequence:

>495_bases
ATGGCCGGCATCGGACAGATCGATACCCCCGGAAGCGAAGCTTCGGGCCAGGAGTTCCTGGTCTTCACGCTGGGAACGGA
GGAATACGGCATCGATATCCTCAAGGTGCAGGAGATCCGCAGCTACGAGACCGTGACGCGCATTGCCAGCGCGCCCGACT
TCATGAAAGGCGTGACCAACCTGCGCGGCGTGATCGTGCCCATCGTCGACCTGCGGCTGAAGTTCCGCCTTGGCAACGTG
CGCTACGACCACCAGACCGTCGTGATCATCCTGAACGTGGCGGGCCGCGTGGTCGGCATCGTCGTGGACGGCGTCTCCGA
CGTGCTCACGCTGACCGGCGAAGCGATCAAGCCGGCGCCGGAGTTCGGCGTGTCGGTGTCCACCGAGCACCTGACAGGCC
TGGCCACGGTCGAAGGCCGCATGCTGGTGCTGATCGATATCGAGCGCCTGATCACCAGCCCCGAGATGGAGCTGATCGAG
GCTGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGATCGTCGATGTCGGTGCGCTGCAGCGCACCGGCGTGCGCCGGCAAGAAACGACGCTGGCGCTGTAATCGTCCAA
CCAAAGGAGAACTAGACATC

Downstream 100 bases:

>100_bases
GCGGCCGACGCGCGATCCGCATCTTGCCGCATTACCCGTATTGCCACGCGAACCCATGACGCCCAACCGTAACGCCGCCA
GCTTTGCCCAAGGCATGGCC

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MAGIGQIDTPGSEASGQEFLVFTLGTEEYGIDILKVQEIRSYETVTRIASAPDFMKGVTNLRGVIVPIVDLRLKFRLGNV
RYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGEAIKPAPEFGVSVSTEHLTGLATVEGRMLVLIDIERLITSPEMELIE
AEAA

Sequences:

>Translated_164_residues
MAGIGQIDTPGSEASGQEFLVFTLGTEEYGIDILKVQEIRSYETVTRIASAPDFMKGVTNLRGVIVPIVDLRLKFRLGNV
RYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGEAIKPAPEFGVSVSTEHLTGLATVEGRMLVLIDIERLITSPEMELIE
AEAA
>Mature_163_residues
AGIGQIDTPGSEASGQEFLVFTLGTEEYGIDILKVQEIRSYETVTRIASAPDFMKGVTNLRGVIVPIVDLRLKFRLGNVR
YDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGEAIKPAPEFGVSVSTEHLTGLATVEGRMLVLIDIERLITSPEMELIEA
EAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=164, Percent_Identity=65.2439024390244, Blast_Score=216, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17665; Mature: 17534

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIGQIDTPGSEASGQEFLVFTLGTEEYGIDILKVQEIRSYETVTRIASAPDFMKGVTN
CCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHH
LRGVIVPIVDLRLKFRLGNVRYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGEAIKPAP
HCEEEEEEEEEEEEEEECCEEECCEEEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCC
EFGVSVSTEHLTGLATVEGRMLVLIDIERLITSPEMELIEAEAA
CCCCEEEHHHHEEEEEECCCEEEEEEEHHHHCCCCCEEEEECCC
>Mature Secondary Structure 
AGIGQIDTPGSEASGQEFLVFTLGTEEYGIDILKVQEIRSYETVTRIASAPDFMKGVTN
CCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHH
LRGVIVPIVDLRLKFRLGNVRYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGEAIKPAP
HCEEEEEEEEEEEEEEECCEEECCEEEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCC
EFGVSVSTEHLTGLATVEGRMLVLIDIERLITSPEMELIEAEAA
CCCCEEEHHHHEEEEEECCCEEEEEEEHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]