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The map label for this gene is cheA [H]

Identifier: 73539430

GI number: 73539430

Start: 2427200

End: 2429221

Strand: Direct

Name: cheA [H]

Synonym: Reut_B5608

Alternate gene names: 73539430

Gene position: 2427200-2429221 (Clockwise)

Preceding gene: 73539429

Following gene: 73539431

Centisome position: 89.03

GC content: 64.49

Gene sequence:

>2022_bases
ATGTCTGTCGATATCGATATCACACAGTTTTACCAGACCTTCTTTGAAGAGGCGGAAGAACTGCTCGTTGAAATGGAGCA
GTTGCTGCTCGGCCTGGACATCGAGTCGCCCGACCCGGAAGACCTCAACGCGATCTTCCGTGCCGCGCACTCCATCAAGG
GCGGTGCGGCTACCTTCGGGTTTGCGGCACTGACCGAAACCACGCACATCTTCGAGAATCTGCTGGACCGTACGCGCCGC
CAGGAACTGGCGCTGTCCCGGACCATCATCGACACCTTTCTGGAAACCAAGGACGTGTTGCAAGATCAGCTCAACGCCTA
CCGCAACGGCACCGAACCCGATCAGGAAACACTGGTGCGCATCTGCGCCGTGCTGCAGCAGCTTGCCCAGGAGGCGAATG
GCACGGCAGGCGGATCCGCTCCGGCTCCCGCAGCGGCACCGGTACCTGTAGTCGCGCCCGTTGCGGCGCCCGCTGCCGGC
GGTGGCCTCAAGGTGCGCCTGATCAAGGTGTCTGCCTCCGACCAGGCATTGCTGCGCGAAGAGCTTGCAAACCTTGGCGA
GATCACCGGGCAGCACGAAGAAAACGGCGAACTGGCGATCTGGCTCAACAGCCAGTGCAGCGCTGACGACATCATTGCCG
TCTGCTGTTTCGTGATCGATGCCGACCAGATCGTGGTCGAGGCAGCCGGCGCATCGGCTCAGGCTCCCGCGCTGGCCGAG
GTGCCTGTTGCCGCTGCGGCGCCAGCGCCGGTTGCGGCCGCACCGGTCGCCGCCACGCCGGCACCCGCTGCCAAGGAGAA
GACCAAGCCGGCCGCAGCGGCCGCCCACAATCAGGAGTCGGGCTCGATCCGCGTGCCGACCGAGAAGGTCGACCAGATCA
TCAACCTGGTGGGCGAACTCGTTATCACGCAATCGATGCTGGCGCAGACCGCGTCGTCGCTCGACCCGGTTCTGTTCGAT
CGCCTGTTCTCCGGCATGGGCCAGCTCGAGCGCAATGCGCGCGACCTGCAGGAAGCCGTGATGTCGATCCGCATGATGCC
GATGGACTACGTGTTCTCGCGCTTTCCGCGCCTGGTCCGCGACCTGGCCAGCAAGCTCGGCAAGCAGATCGACCTGGTGA
CGTTCGGCAAGGCGACCGAGCTCGACAAGAGCCTGATCGAACGCATCATCGACCCGCTGACCCACCTCGTGCGCAACAGC
CTGGACCACGGCATCGAGACGCCGGACAAGCGCGTCGCCGCGGGCAAGGATCCGACCGGCCAGCTCATCCTCTCCGCGCA
GCACCACGGCGGCAATATCGTGATCGAGGTCAGCGACGACGGCGGTGGCCTGAACCGCGAGCGCATCCTTGCCAAGGCGA
TCCAGAACGGCCTGCCGGTGTCCGAGAACATCAGTGATGAAGAAGTCTGGCAACTGATCTTCGCGCCGGGCTTCTCTACG
GCAGAAGTCGTGACCGACGTTTCCGGCCGTGGCGTGGGCATGGACGTGGTCAAGCGGAACATCCAGGAGATGGGCGGCCA
TGTCGAGATCAGCTGCCGTCCGGGCCTGGGCACCACGATCCGCATCGTGCTGCCGCTGACGCTGGCGATTCTCGACGGCA
TGTCGGTGAAGGTCGGCGAGGAAACCTTCATCCTGCCGCTGAACTGCGTGATGGAGTCGCTGCAGCCGAAGTCCGAGGAC
ATCCATACCGCAGCCAACGCCGACCGCGTCATGCACGTGCGCGGCGAATACCTGCCGCTGCTCGAGATGCACCGCGTCTT
CAACGTGGCTGACGCGCTGCAGGAGCCGACCCAGGGCATCGCCGTGATCCTGCAGGCCGAAGGCAAGCGCTTCGCGCTGC
TGGTGGACCAGCTCATCGGCCAGCACCAGGTCGTGCTGAAGAACCTGGAAACCAACTACCGCAAGGTGCCATGCATTTCC
GCCGCCACCATTCTCGGCGACGGCAGCGTGGCGCTGATCGTCGATGTCGGTGCGCTGCAGCGCACCGGCGTGCGCCGGCA
AGAAACGACGCTGGCGCTGTAA

Upstream 100 bases:

>100_bases
ACCGGCAGCACCGGCGGCGCCGAAGGCAAAGACAGAATGATGCGTGGCCGCTGGCATGGCGGCGATGCTTAGCGCAGTAA
CTTAGTGAGTCAGGACGCCA

Downstream 100 bases:

>100_bases
TCGTCCAACCAAAGGAGAACTAGACATCATGGCCGGCATCGGACAGATCGATACCCCCGGAAGCGAAGCTTCGGGCCAGG
AGTTCCTGGTCTTCACGCTG

Product: CheW-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEDLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRR
QELALSRTIIDTFLETKDVLQDQLNAYRNGTEPDQETLVRICAVLQQLAQEANGTAGGSAPAPAAAPVPVVAPVAAPAAG
GGLKVRLIKVSASDQALLREELANLGEITGQHEENGELAIWLNSQCSADDIIAVCCFVIDADQIVVEAAGASAQAPALAE
VPVAAAAPAPVAAAPVAATPAPAAKEKTKPAAAAAHNQESGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFD
RLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNS
LDHGIETPDKRVAAGKDPTGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENISDEEVWQLIFAPGFST
AEVVTDVSGRGVGMDVVKRNIQEMGGHVEISCRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKSED
IHTAANADRVMHVRGEYLPLLEMHRVFNVADALQEPTQGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCIS
AATILGDGSVALIVDVGALQRTGVRRQETTLAL

Sequences:

>Translated_673_residues
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEDLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRR
QELALSRTIIDTFLETKDVLQDQLNAYRNGTEPDQETLVRICAVLQQLAQEANGTAGGSAPAPAAAPVPVVAPVAAPAAG
GGLKVRLIKVSASDQALLREELANLGEITGQHEENGELAIWLNSQCSADDIIAVCCFVIDADQIVVEAAGASAQAPALAE
VPVAAAAPAPVAAAPVAATPAPAAKEKTKPAAAAAHNQESGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFD
RLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNS
LDHGIETPDKRVAAGKDPTGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENISDEEVWQLIFAPGFST
AEVVTDVSGRGVGMDVVKRNIQEMGGHVEISCRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKSED
IHTAANADRVMHVRGEYLPLLEMHRVFNVADALQEPTQGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCIS
AATILGDGSVALIVDVGALQRTGVRRQETTLAL
>Mature_672_residues
SVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEDLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRRQ
ELALSRTIIDTFLETKDVLQDQLNAYRNGTEPDQETLVRICAVLQQLAQEANGTAGGSAPAPAAAPVPVVAPVAAPAAGG
GLKVRLIKVSASDQALLREELANLGEITGQHEENGELAIWLNSQCSADDIIAVCCFVIDADQIVVEAAGASAQAPALAEV
PVAAAAPAPVAAAPVAATPAPAAKEKTKPAAAAAHNQESGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFDR
LFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSL
DHGIETPDKRVAAGKDPTGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENISDEEVWQLIFAPGFSTA
EVVTDVSGRGVGMDVVKRNIQEMGGHVEISCRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKSEDI
HTAANADRVMHVRGEYLPLLEMHRVFNVADALQEPTQGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISA
ATILGDGSVALIVDVGALQRTGVRRQETTLAL

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=664, Percent_Identity=62.3493975903614, Blast_Score=785, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72087; Mature: 71956

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEDLNAIFRAAHSIKGGAATFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FAALTETTHIFENLLDRTRRQELALSRTIIDTFLETKDVLQDQLNAYRNGTEPDQETLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEANGTAGGSAPAPAAAPVPVVAPVAAPAAGGGLKVRLIKVSASDQALLRE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCHHHHHHH
ELANLGEITGQHEENGELAIWLNSQCSADDIIAVCCFVIDADQIVVEAAGASAQAPALAE
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCHHC
VPVAAAAPAPVAAAPVAATPAPAAKEKTKPAAAAAHNQESGSIRVPTEKVDQIINLVGEL
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCCCCCEECCHHHHHHHHHHHHHH
VITQSMLAQTASSLDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIETPDKRVAAGKDPTG
HHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
QLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENISDEEVWQLIFAPGFST
CEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCH
AEVVTDVSGRGVGMDVVKRNIQEMGGHVEISCRPGLGTTIRIVLPLTLAILDGMSVKVGE
HHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCEEEECC
ETFILPLNCVMESLQPKSEDIHTAANADRVMHVRGEYLPLLEMHRVFNVADALQEPTQGI
CEEEEEHHHHHHHCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
AVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQ
EEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHH
RTGVRRQETTLAL
HCCCCHHHHCCCC
>Mature Secondary Structure 
SVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEDLNAIFRAAHSIKGGAATFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FAALTETTHIFENLLDRTRRQELALSRTIIDTFLETKDVLQDQLNAYRNGTEPDQETLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEANGTAGGSAPAPAAAPVPVVAPVAAPAAGGGLKVRLIKVSASDQALLRE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCHHHHHHH
ELANLGEITGQHEENGELAIWLNSQCSADDIIAVCCFVIDADQIVVEAAGASAQAPALAE
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCHHC
VPVAAAAPAPVAAAPVAATPAPAAKEKTKPAAAAAHNQESGSIRVPTEKVDQIINLVGEL
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCCCCCEECCHHHHHHHHHHHHHH
VITQSMLAQTASSLDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIETPDKRVAAGKDPTG
HHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
QLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENISDEEVWQLIFAPGFST
CEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCH
AEVVTDVSGRGVGMDVVKRNIQEMGGHVEISCRPGLGTTIRIVLPLTLAILDGMSVKVGE
HHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCEEEECC
ETFILPLNCVMESLQPKSEDIHTAANADRVMHVRGEYLPLLEMHRVFNVADALQEPTQGI
CEEEEEHHHHHHHCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
AVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQ
EEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHH
RTGVRRQETTLAL
HCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]