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The map label for this gene is tcp [H]

Identifier: 73539424

GI number: 73539424

Start: 2421259

End: 2423043

Strand: Direct

Name: tcp [H]

Synonym: Reut_B5602

Alternate gene names: 73539424

Gene position: 2421259-2423043 (Clockwise)

Preceding gene: 73539423

Following gene: 73539425

Centisome position: 88.82

GC content: 66.27

Gene sequence:

>1785_bases
ATGCATTGGTTCAATCAACTGCGGGTTACGACCCGGCTGGTTGGCGGGTTCCTGGTGGTCGCAGTGATCGGTGCCTTCAT
GGGGCTGCTCGGCGTCGTCAATATGGGGCGCATGGCCGACTGGACCGGCAAGATCTACAACAACGACTTGCAGGCGCTGA
AAGCGGTGCAGGACGCCAATATCAATCTGGTCTATGCCAGCCGTGCGCAGATCGCGCTGCTGTCGGCATCGACCATGGGC
GAGCGCAGCACCGAGAAGGAACAGATCACCAAGTCGCTCGCCGCCATGGACGAGCGCGTGAAGCAGGTGGCCGACAAGTT
CGAACAGCCGGAGGGCAAGGCGCTGGTCAAGCAATACCAGACGCTGGCGCCGGCGTTCCGCGAACGCATGGGCAAGTACA
CGGAGCTCGTGAGCAAGCAGCCGCTCGATACCTCGCAGTTCGAAAGCAGCGTGTTCAGCGAGAGCGCAGACCTGCTCAAG
GACAGCCATGCGCTTGAAGCGATCATGGCCACGATGGTCAAGCGCCGCGATGACCGCGCACGCTCCAACATGGAAGAGGC
GCGCAGCGTCTATACGAGCACGCGCCTGTGGATGCTCGGCCTCGTGCTCGGCGGCCTGGCGCTGTCGGTGCTGCTTGGCG
CTTTCCTGGCGCGCGCGCTGTCGCGTCAACTCGGCGGCGAGCCCAGTTACGCCGTGGCCATTGCTTCGCGCATTGCCGAT
GGCGATTTCTCCGCCGAAGTGAAGACGCGTGCCGGCGATCGCGACAGCTTGGTCCACGCCATGAAGCAGATGCAGCAGCA
GCTGTCGGGCATGGTGCGCGACTTCAAGGAGTCGGCTGAGTCGATCGCCACGGCATCGCGCGAGATTGCCGCGGGCAACA
ACGACCTGTCGCAGCGCACCGAGCAGCAGGCGGCGTCGCTGGAAGAGACGGCATCGAGCATGGAGGAGCTGACCAGCACG
GTGCGCCAGAACGCAGACAACGCGCGCCAGGCGAGCGGGCTGGCGGCGAATGCGTCGGAAACCGCGGTGCGCGGTGGCGA
AGTGGTCGGCCGCGTGGTGAACACGATGGAAGAGATCAACGAAGCGTCGCGCAAGATCGTGGACATCATCGGCGTGATCG
AAGGCATTGCGTTCCAGACCAATATCCTGGCGCTGAACGCGGCGGTGGAAGCCGCACGTGCGGGCGAACAAGGTCGTGGC
TTTGCGGTCGTGGCAGGCGAGGTGCGCAGCCTTGCACAGCGCAGCGCGAATGCCGCCAAGGAAATCAAGGGCCTGATCGG
CGACACGGTGGCGCGCGTGGACAACGGCACAGCGCTGGTGGGCCAGGCTGGCACGACGATGGACGAGATCGTGCAGGCGG
TCAAGCGCGTGACGGACATCATGAGCGAGATCAGCGCGGCCTCGGCCGAGCAGAGTTCGGGCATCGAACAGGTGAACCAG
GCCGTGGCGCAGATGGATGAGGTGACGCAGCAGAATGCGGCACTGGTGGAGCAGGCTGCAGCCGCCGCAGGCTCGCTCCA
GGACCAGGCCGGCCGCCTGCAGACGGTGGTCGCCACGTTCCGTCTGGCTGCGGATGGCTCGGTAGCCTCGGCCCGCTTCG
AACGGTCTGCCGCAGCCCATTCCACGGCACGCCCAACCGGCAAGGCCGCACTCGCGTCGGCGCGCAAGCCCGCACCGACT
GCAGATGCCGCGGAGCCGACGAGCCAGCCGGCGGCGAAGGCCCGTGCGCTACCGCGCCCGGCCGCTCTCGCCGCCGCGGA
CAACGGGGACTGGAGCGCGTTCTGA

Upstream 100 bases:

>100_bases
CTGTCGCTGGCGCAGGCTTGAGACAGGCAGGGCGCGACGGCCGCGTGCTACCGCACGCCGGTGGGGCGTACCCGGATCAT
TCGTTACAAGGGGGATTTCT

Downstream 100 bases:

>100_bases
GCCCCGGCGGGCGGCAATCGGTTGCTACGGCCTGCCGCCCGCCTTCGCCTTCGATGCCATGAATACCAATATCACCCTGG
CCTTGTCGCCAGACGAGGTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MHWFNQLRVTTRLVGGFLVVAVIGAFMGLLGVVNMGRMADWTGKIYNNDLQALKAVQDANINLVYASRAQIALLSASTMG
ERSTEKEQITKSLAAMDERVKQVADKFEQPEGKALVKQYQTLAPAFRERMGKYTELVSKQPLDTSQFESSVFSESADLLK
DSHALEAIMATMVKRRDDRARSNMEEARSVYTSTRLWMLGLVLGGLALSVLLGAFLARALSRQLGGEPSYAVAIASRIAD
GDFSAEVKTRAGDRDSLVHAMKQMQQQLSGMVRDFKESAESIATASREIAAGNNDLSQRTEQQAASLEETASSMEELTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQVNQ
AVAQMDEVTQQNAALVEQAAAAAGSLQDQAGRLQTVVATFRLAADGSVASARFERSAAAHSTARPTGKAALASARKPAPT
ADAAEPTSQPAAKARALPRPAALAAADNGDWSAF

Sequences:

>Translated_594_residues
MHWFNQLRVTTRLVGGFLVVAVIGAFMGLLGVVNMGRMADWTGKIYNNDLQALKAVQDANINLVYASRAQIALLSASTMG
ERSTEKEQITKSLAAMDERVKQVADKFEQPEGKALVKQYQTLAPAFRERMGKYTELVSKQPLDTSQFESSVFSESADLLK
DSHALEAIMATMVKRRDDRARSNMEEARSVYTSTRLWMLGLVLGGLALSVLLGAFLARALSRQLGGEPSYAVAIASRIAD
GDFSAEVKTRAGDRDSLVHAMKQMQQQLSGMVRDFKESAESIATASREIAAGNNDLSQRTEQQAASLEETASSMEELTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQVNQ
AVAQMDEVTQQNAALVEQAAAAAGSLQDQAGRLQTVVATFRLAADGSVASARFERSAAAHSTARPTGKAALASARKPAPT
ADAAEPTSQPAAKARALPRPAALAAADNGDWSAF
>Mature_594_residues
MHWFNQLRVTTRLVGGFLVVAVIGAFMGLLGVVNMGRMADWTGKIYNNDLQALKAVQDANINLVYASRAQIALLSASTMG
ERSTEKEQITKSLAAMDERVKQVADKFEQPEGKALVKQYQTLAPAFRERMGKYTELVSKQPLDTSQFESSVFSESADLLK
DSHALEAIMATMVKRRDDRARSNMEEARSVYTSTRLWMLGLVLGGLALSVLLGAFLARALSRQLGGEPSYAVAIASRIAD
GDFSAEVKTRAGDRDSLVHAMKQMQQQLSGMVRDFKESAESIATASREIAAGNNDLSQRTEQQAASLEETASSMEELTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQVNQ
AVAQMDEVTQQNAALVEQAAAAAGSLQDQAGRLQTVVATFRLAADGSVASARFERSAAAHSTARPTGKAALASARKPAPT
ADAAEPTSQPAAKARALPRPAALAAADNGDWSAF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=277, Percent_Identity=64.6209386281588, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1788194, Length=561, Percent_Identity=40.8199643493761, Blast_Score=306, Evalue=3e-84,
Organism=Escherichia coli, GI2367378, Length=287, Percent_Identity=64.1114982578397, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1787690, Length=451, Percent_Identity=44.7893569844789, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1789453, Length=287, Percent_Identity=39.3728222996516, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62907; Mature: 62907

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWFNQLRVTTRLVGGFLVVAVIGAFMGLLGVVNMGRMADWTGKIYNNDLQALKAVQDAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
INLVYASRAQIALLSASTMGERSTEKEQITKSLAAMDERVKQVADKFEQPEGKALVKQYQ
CEEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLAPAFRERMGKYTELVSKQPLDTSQFESSVFSESADLLKDSHALEAIMATMVKRRDDRA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSNMEEARSVYTSTRLWMLGLVLGGLALSVLLGAFLARALSRQLGGEPSYAVAIASRIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GDFSAEVKTRAGDRDSLVHAMKQMQQQLSGMVRDFKESAESIATASREIAAGNNDLSQRT
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EQQAASLEETASSMEELTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQVNQ
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
AVAQMDEVTQQNAALVEQAAAAAGSLQDQAGRLQTVVATFRLAADGSVASARFERSAAAH
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
STARPTGKAALASARKPAPTADAAEPTSQPAAKARALPRPAALAAADNGDWSAF
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHEECCCCCCCCC
>Mature Secondary Structure
MHWFNQLRVTTRLVGGFLVVAVIGAFMGLLGVVNMGRMADWTGKIYNNDLQALKAVQDAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
INLVYASRAQIALLSASTMGERSTEKEQITKSLAAMDERVKQVADKFEQPEGKALVKQYQ
CEEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLAPAFRERMGKYTELVSKQPLDTSQFESSVFSESADLLKDSHALEAIMATMVKRRDDRA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSNMEEARSVYTSTRLWMLGLVLGGLALSVLLGAFLARALSRQLGGEPSYAVAIASRIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GDFSAEVKTRAGDRDSLVHAMKQMQQQLSGMVRDFKESAESIATASREIAAGNNDLSQRT
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EQQAASLEETASSMEELTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQVNQ
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
AVAQMDEVTQQNAALVEQAAAAAGSLQDQAGRLQTVVATFRLAADGSVASARFERSAAAH
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
STARPTGKAALASARKPAPTADAAEPTSQPAAKARALPRPAALAAADNGDWSAF
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]