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The map label for this gene is aer [H]

Identifier: 73539423

GI number: 73539423

Start: 2419524

End: 2421179

Strand: Direct

Name: aer [H]

Synonym: Reut_B5601

Alternate gene names: 73539423

Gene position: 2419524-2421179 (Clockwise)

Preceding gene: 73539422

Following gene: 73539424

Centisome position: 88.75

GC content: 66.73

Gene sequence:

>1656_bases
ATGTCATACATGCGAAACAACCAACCCGTCACGCAAAACGAATACAAGCTTTCCCCTGACGACTACCTGATTTCGCGTAC
CGACCTCAAAGGCCGCATCACGTTCGCCAACCGTACGTTCGTTGAGGCAAGCGGCTTCAGCGCGCAGGAACTGCTGGGCG
CGGCGCACAACCTAGTGCGTCATCCCGACATGCCGCCGGAGGCCTTTGCCGACCTGTGGCAGAACATCCAGGCAGGCCGT
TCGTGGGTGGGCGTGGTCAAGAACCGCCGCAAGAACGGCGACTACTACTGGGTCAGCGCGACGGTCACGCCGACCCATAT
CGATGGTCGCCTGGTGGGCTATACCTCCGTGCGCTCGATGGCCACACGCGAACAGGTCGAGGCGGCCAGCGCCGCTTACG
CGCGCTTCCGCGAAGGACGCGCGGGCGGCCTGGCCATCCGCGAGGGGGCCGTGGTGCGTACCGGCATGGCGGGATGGGTC
GGCCGTGCCACGCGCCTGAACCTGCGCCGGCGCATCCTGTGGTCGCAAGCGGGCGGCCTGGTGTGGTTCCTGGCGGCGCT
GCTGGCCGCCGAAGCATTCGGTGGCGACGCCGTCGCCGCGGTACGTCCCTGGCTGTGGGGCGGCTTCGTGCTGGCGGTCG
TGACCGCCTTCGCGACCGGCACGATGCTGCTGTCGCGCGTGCATCGTCCCGTTCGCGAAATGCTCGACTTTGCTCTGCGC
ATGGGCGCAGGGGACCTCACCACCAGTTTTGAACATCGCGCGAACGATGAGGTCGGCGCACTCGCGCAGGCTATGCAGAC
CATGCAGCGCAGCCTGCTGTCCGTGGTGCACGAGATCCAGGAAGGCATGGCCAGCATTTCGTCGGCGACCCACCAGGTGG
CCGCGGGCAACAACGACCTGTCGCAGCGCACCGAGCAGCAGGCGGCGTCGCTGGAAGAGACGGCATCGAGCATGGAGGAG
CTGACCAGCACGGTGCGCCAGAACGCAGACAACGCGCGCCAGGCGAGCGGGCTGGCGGCGAATGCGTCGGAAACCGCGGT
GCGCGGTGGCGAAGTGGTCGGCCGCGTGGTGAACACGATGGAAGAGATCAACGAAGCGTCGCGCAAGATCGTGGACATCA
TCGGCGTGATCGAAGGCATTGCGTTCCAGACCAATATCCTGGCGCTGAACGCGGCGGTGGAAGCCGCACGTGCGGGCGAA
CAAGGTCGTGGCTTTGCGGTCGTGGCAGGCGAGGTGCGCAGCCTTGCACAGCGCAGCGCGAATGCCGCCAAGGAAATCAA
GGGCCTGATCGGCGACACGGTGGCGCGCGTGGACAACGGCACAGCGCTGGTGGGCCAGGCTGGCACGACGATGGACGAGA
TCGTGCAGGCGGTCAAGCGCGTGACGGACATCATGAGCGAGATCAGCGCGGCCTCGGCCGAGCAGAGTTCGGGCATCGAA
CAGGTGAACCAGGCCGTGGCGCAGATGGATGAAGTGACACAGCAGAACGCGGCACTCGTCGAGCAGGCTGCAGCGGCGGC
CGGTTCGCTCGAAGAGCAGGCGGAACGCTTGCGCGACGCGGTAGCGACCTTCCGCGTCAGCATGCAGGCAGAGGTGCGGC
CCCAGCGGCCGCGCCGCGCCGATACAGAAGGGGTGCTGTCGCTGGCGCAGGCTTGA

Upstream 100 bases:

>100_bases
CCGGCCAGCGGAGCCGGCACCCACCCGTGCCGCCGCACCCCCGCCAAACCGCTTTGAGTGGTGCCGCAATCGCAGCCGCC
GTGCCCAAAGCAAGCAGTTA

Downstream 100 bases:

>100_bases
GACAGGCAGGGCGCGACGGCCGCGTGCTACCGCACGCCGGTGGGGCGTACCCGGATCATTCGTTACAAGGGGGATTTCTA
TGCATTGGTTCAATCAACTG

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSYMRNNQPVTQNEYKLSPDDYLISRTDLKGRITFANRTFVEASGFSAQELLGAAHNLVRHPDMPPEAFADLWQNIQAGR
SWVGVVKNRRKNGDYYWVSATVTPTHIDGRLVGYTSVRSMATREQVEAASAAYARFREGRAGGLAIREGAVVRTGMAGWV
GRATRLNLRRRILWSQAGGLVWFLAALLAAEAFGGDAVAAVRPWLWGGFVLAVVTAFATGTMLLSRVHRPVREMLDFALR
MGAGDLTTSFEHRANDEVGALAQAMQTMQRSLLSVVHEIQEGMASISSATHQVAAGNNDLSQRTEQQAASLEETASSMEE
LTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGE
QGRGFAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIE
QVNQAVAQMDEVTQQNAALVEQAAAAAGSLEEQAERLRDAVATFRVSMQAEVRPQRPRRADTEGVLSLAQA

Sequences:

>Translated_551_residues
MSYMRNNQPVTQNEYKLSPDDYLISRTDLKGRITFANRTFVEASGFSAQELLGAAHNLVRHPDMPPEAFADLWQNIQAGR
SWVGVVKNRRKNGDYYWVSATVTPTHIDGRLVGYTSVRSMATREQVEAASAAYARFREGRAGGLAIREGAVVRTGMAGWV
GRATRLNLRRRILWSQAGGLVWFLAALLAAEAFGGDAVAAVRPWLWGGFVLAVVTAFATGTMLLSRVHRPVREMLDFALR
MGAGDLTTSFEHRANDEVGALAQAMQTMQRSLLSVVHEIQEGMASISSATHQVAAGNNDLSQRTEQQAASLEETASSMEE
LTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGE
QGRGFAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIE
QVNQAVAQMDEVTQQNAALVEQAAAAAGSLEEQAERLRDAVATFRVSMQAEVRPQRPRRADTEGVLSLAQA
>Mature_550_residues
SYMRNNQPVTQNEYKLSPDDYLISRTDLKGRITFANRTFVEASGFSAQELLGAAHNLVRHPDMPPEAFADLWQNIQAGRS
WVGVVKNRRKNGDYYWVSATVTPTHIDGRLVGYTSVRSMATREQVEAASAAYARFREGRAGGLAIREGAVVRTGMAGWVG
RATRLNLRRRILWSQAGGLVWFLAALLAAEAFGGDAVAAVRPWLWGGFVLAVVTAFATGTMLLSRVHRPVREMLDFALRM
GAGDLTTSFEHRANDEVGALAQAMQTMQRSLLSVVHEIQEGMASISSATHQVAAGNNDLSQRTEQQAASLEETASSMEEL
TSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTMEEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQ
GRGFAVVAGEVRSLAQRSANAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIEQ
VNQAVAQMDEVTQQNAALVEQAAAAAGSLEEQAERLRDAVATFRVSMQAEVRPQRPRRADTEGVLSLAQA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=529, Percent_Identity=38.1852551984877, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1788195, Length=323, Percent_Identity=59.7523219814242, Blast_Score=328, Evalue=6e-91,
Organism=Escherichia coli, GI2367378, Length=352, Percent_Identity=57.6704545454545, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=55.2552552552552, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=56.7656765676568, Blast_Score=300, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59095; Mature: 58964

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYMRNNQPVTQNEYKLSPDDYLISRTDLKGRITFANRTFVEASGFSAQELLGAAHNLVR
CCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHC
HPDMPPEAFADLWQNIQAGRSWVGVVKNRRKNGDYYWVSATVTPTHIDGRLVGYTSVRSM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCCEEEEHHHHHHH
ATREQVEAASAAYARFREGRAGGLAIREGAVVRTGMAGWVGRATRLNLRRRILWSQAGGL
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
VWFLAALLAAEAFGGDAVAAVRPWLWGGFVLAVVTAFATGTMLLSRVHRPVREMLDFALR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGAGDLTTSFEHRANDEVGALAQAMQTMQRSLLSVVHEIQEGMASISSATHQVAAGNNDL
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SQRTEQQAASLEETASSMEELTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHH
NAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHH
QVNQAVAQMDEVTQQNAALVEQAAAAAGSLEEQAERLRDAVATFRVSMQAEVRPQRPRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DTEGVLSLAQA
CHHHHHHHHCC
>Mature Secondary Structure 
SYMRNNQPVTQNEYKLSPDDYLISRTDLKGRITFANRTFVEASGFSAQELLGAAHNLVR
CCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHC
HPDMPPEAFADLWQNIQAGRSWVGVVKNRRKNGDYYWVSATVTPTHIDGRLVGYTSVRSM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCCEEEEHHHHHHH
ATREQVEAASAAYARFREGRAGGLAIREGAVVRTGMAGWVGRATRLNLRRRILWSQAGGL
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
VWFLAALLAAEAFGGDAVAAVRPWLWGGFVLAVVTAFATGTMLLSRVHRPVREMLDFALR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGAGDLTTSFEHRANDEVGALAQAMQTMQRSLLSVVHEIQEGMASISSATHQVAAGNNDL
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SQRTEQQAASLEETASSMEELTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVNTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHH
NAAKEIKGLIGDTVARVDNGTALVGQAGTTMDEIVQAVKRVTDIMSEISAASAEQSSGIE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHH
QVNQAVAQMDEVTQQNAALVEQAAAAAGSLEEQAERLRDAVATFRVSMQAEVRPQRPRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DTEGVLSLAQA
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]