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The map label for this gene is cmpR [H]

Identifier: 73539340

GI number: 73539340

Start: 2315250

End: 2316128

Strand: Direct

Name: cmpR [H]

Synonym: Reut_B5518

Alternate gene names: 73539340

Gene position: 2315250-2316128 (Clockwise)

Preceding gene: 73539337

Following gene: 73539342

Centisome position: 84.93

GC content: 65.76

Gene sequence:

>879_bases
ATGCTTATCGCCCAGCTCAAGTCGTTCTTCATGGTGGCTCGCATCGGCAGCGTGACGCAGGCCGCCAAGCGGCTGGGCTT
GTCGCAGCCGACCATCACCGCGCAGATCCGCGCGCTCGAAGAGGCCTATGGCGTCGAGCTGTTCCACCGCGGCGGCAGGC
GTCTGGCGCTGTCCGATGCGGGGCTGACGCTGCTGCCCAAGGTCGAGACGCTGGTCCAGCAGGAAACGGAAATCGATTTC
TTCCTGCGCCATTCGGGCGACCTGCGCACGGGCAGCCTGCGCATCGGCGCCACCGCGCCGTACTATGTGCTGGACCTCAT
CCGCCGCTTCAGCGCACGCTATCCGGCCATCGACGTCACGGTCGAGATGGGCAACTCGCAGGAAATGCTCAATGCCCTGC
AGGAGTACCGCGTGGACGTGGCCATGTCGTCCAATTTCGTGGATGACCCGCGCCTGTCGCGGCTGCTGCTGGGCGTGGAT
CCGCTCGTGCTGGTCGTGCATCGCACCCATCCTTTGGCCGGGCGAACCGAAATCACCCCCGCCGCACTCGCTGGGTGCCG
GCTGCTGATGCGGGAAGCGGGATCCACCACGCGCATCGCGACCGAGCAGATGCTGGCCGAGGCCAATGTCGTGCCTGGTT
CCCAGATGGAAATCGGCAGCCGCGAGTCGATTCGCGAGGCCGTGGTGCGCAATCTCGGCGTGTCGGTGATCGCGCTGCAT
GAAGTGCCGAGCCACGCGGACCTGCGCGTGCTGCACTTCACGGGCGGATCGCCGCAATTGCACGAGTACATGTACTGCCT
GCGCGAACGTCGGCAGGCCCGGCTCATCGATGCGTTTGTCTCGCTTGCGGAGCCAGCCGGGAAGAGAACCGAGGATTAG

Upstream 100 bases:

>100_bases
GCATGGCCATCTGGCGGCCCGTCACGTGGCCGTCCTCTAGAATAGTGCTTCATTGTGACCGGCACTCACGCCATTCTTAC
GCCATTCCCCTGCCACCAGC

Downstream 100 bases:

>100_bases
CGCGCAGCAGGTGTGAGGAAAGCGGCACCCGCCACGCGCACTATTGGCTCGGTCAGGCCGTCATCTTCAGGCAGGCTTCC
ATGCAGGCCGCGCAAGCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLTLLPKVETLVQQETEIDF
FLRHSGDLRTGSLRIGATAPYYVLDLIRRFSARYPAIDVTVEMGNSQEMLNALQEYRVDVAMSSNFVDDPRLSRLLLGVD
PLVLVVHRTHPLAGRTEITPAALAGCRLLMREAGSTTRIATEQMLAEANVVPGSQMEIGSRESIREAVVRNLGVSVIALH
EVPSHADLRVLHFTGGSPQLHEYMYCLRERRQARLIDAFVSLAEPAGKRTED

Sequences:

>Translated_292_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLTLLPKVETLVQQETEIDF
FLRHSGDLRTGSLRIGATAPYYVLDLIRRFSARYPAIDVTVEMGNSQEMLNALQEYRVDVAMSSNFVDDPRLSRLLLGVD
PLVLVVHRTHPLAGRTEITPAALAGCRLLMREAGSTTRIATEQMLAEANVVPGSQMEIGSRESIREAVVRNLGVSVIALH
EVPSHADLRVLHFTGGSPQLHEYMYCLRERRQARLIDAFVSLAEPAGKRTED
>Mature_292_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLTLLPKVETLVQQETEIDF
FLRHSGDLRTGSLRIGATAPYYVLDLIRRFSARYPAIDVTVEMGNSQEMLNALQEYRVDVAMSSNFVDDPRLSRLLLGVD
PLVLVVHRTHPLAGRTEITPAALAGCRLLMREAGSTTRIATEQMLAEANVVPGSQMEIGSRESIREAVVRNLGVSVIALH
EVPSHADLRVLHFTGGSPQLHEYMYCLRERRQARLIDAFVSLAEPAGKRTED

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=243, Percent_Identity=32.9218106995885, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI157672245, Length=234, Percent_Identity=31.6239316239316, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693105, Length=209, Percent_Identity=31.1004784688995, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=25.2032520325203, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082132, Length=280, Percent_Identity=27.5, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=26.1044176706827, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787806, Length=293, Percent_Identity=25.5972696245734, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787879, Length=243, Percent_Identity=27.9835390946502, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=238, Percent_Identity=27.7310924369748, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=198, Percent_Identity=30.8080808080808, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=26.530612244898, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787128, Length=141, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32288; Mature: 32288

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GLTLLPKVETLVQQETEIDFFLRHSGDLRTGSLRIGATAPYYVLDLIRRFSARYPAIDVT
CCEEHHHHHHHHHHHCCCEEEEECCCCCEECCEEECCCCHHHHHHHHHHHHCCCCEEEEE
VEMGNSQEMLNALQEYRVDVAMSSNFVDDPRLSRLLLGVDPLVLVVHRTHPLAGRTEITP
EEECCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
AALAGCRLLMREAGSTTRIATEQMLAEANVVPGSQMEIGSRESIREAVVRNLGVSVIALH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
EVPSHADLRVLHFTGGSPQLHEYMYCLRERRQARLIDAFVSLAEPAGKRTED
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GLTLLPKVETLVQQETEIDFFLRHSGDLRTGSLRIGATAPYYVLDLIRRFSARYPAIDVT
CCEEHHHHHHHHHHHCCCEEEEECCCCCEECCEEECCCCHHHHHHHHHHHHCCCCEEEEE
VEMGNSQEMLNALQEYRVDVAMSSNFVDDPRLSRLLLGVDPLVLVVHRTHPLAGRTEITP
EEECCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
AALAGCRLLMREAGSTTRIATEQMLAEANVVPGSQMEIGSRESIREAVVRNLGVSVIALH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
EVPSHADLRVLHFTGGSPQLHEYMYCLRERRQARLIDAFVSLAEPAGKRTED
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]