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The map label for this gene is 73539328

Identifier: 73539328

GI number: 73539328

Start: 2302216

End: 2303307

Strand: Direct

Name: 73539328

Synonym: Reut_B5506

Alternate gene names: NA

Gene position: 2302216-2303307 (Clockwise)

Preceding gene: 73539327

Following gene: 73539329

Centisome position: 84.45

GC content: 65.02

Gene sequence:

>1092_bases
TTGCATACACACTGTGATCACGACGGCTGCCAGTCGCGGCGCCATTTTCTGGGCTCACTGGGAGCGCTGGCAGGCGCTGC
GCTGATGCCGACCGGTCTGGCCAGGGCTCACGCCATCGGCCCCGGCGGCGGGCGTATCGATTTCCACCACCACTACTTTT
CGCCGGCGTGGGTCAGGCTGGTGGAGTCCAAGCACAAGGTCCAGCCCGTACTCGGCTTCGACCAGTTCAAGAGCTGGACG
ATCGCCAGGGACCTGGAAGCAATGGATCGCGGCAATGTCGAGAAGGCCTTCCTGTCGGTCACGCAACCGGGCGTCTGGTT
TGGCAACGTCGAAGAATCGCGGCGTGCGGCGCGTGACATGAACGACTTCGCGGCGACGATGAAGTCGGACCACAAGGGCC
GCTATGGCCAGTTTGCCGTGCTGCCGCTGCCGGATATCGATGCCACGCTGAAGGAGATCGAATACGCGTTCGACACGCTC
AAGGCGGATGGCGTGGGCCTGCTGTCGAGCTATGGCGACAAGTGGCTCGGCGACAAGTCGTTCTGGCCGGTCTGGGAAGA
ACTGAACCGCCGCAAGGCCGTGGTCTATATCCACGCCACGGCGCCGGGCTGCTGCGCGTGGGAATTCCAGCCGGGCATCC
TGCCGACCTTCGTCGAGTTGGGATCCGACCTCGCCCGCGCCATGGTGAGCCTGGTTCAGGGTGGCACGGCGAAGGCGACG
CCGGATATCAAATACATCTGGTCGCACGGCGGCGGCAGCATCTGGGCGCAGCGTTTCCTGGTCGGCGAAACCGCGGCATC
GCTGGCGCGCGAAGCGCCGGCCGACTCGCGCCTGTACCAGTTCCGGCGCTTCTACTACGACACAGCTGCGGCGGCGGACG
CGATCCATATGGGCATCCTGAAGATGGTCGTGCCGCCGAGCCAGATCGTGTTCGGCTCCGACTATCCATGGGTCGAGCCG
GCCAAGATCGCCACGGGCCTGGAAGCATCAGGGCTGTCGCCGCAGGTCCTGCAGGCGGTCTATCGCGACAACGCCTTCCG
GGTGATGCCGCAATTGCGCGAACAACTGGCTGCGGCCGCGCGTACGAACTGA

Upstream 100 bases:

>100_bases
AAAGCGCTATGAAGTCGCGCCCCGCCTGGGCAAGGCCGATCCGTCTTACGCGCTGTTCGGCGAGAAGTAAGCCTCGCATC
TCGCAACGGAGACCCGCATC

Downstream 100 bases:

>100_bases
AAGAGAAGGGCGGAGAGCCAGCAATGCAATTCAAGAGCATCAAGTGGGTAGCGGCCGCGTTGTGGGTATTGCCGCTGGTT
GCGGCGGCACAGTCGTTCCC

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: Metal-Dependent Hydrolase; Amidohydrolase Family Protein; Aminocarboxymuconate-Semialdehyde Decarboxylase; Amidohydrolase Family; 2-Amino-3-Carboxylmuconate-6-Semialdehyde Decarboxylase; Twin-Arginine Translocation Pathway Signal; O-Pyrocatechuate Decarboxylase; Hydrolase; 2 3-Dihydroxybenzoic Acid Decarboxylase; 2-Amino-3-Carboxymuconate 6-Semialdehyde Decarboxylase

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MHTHCDHDGCQSRRHFLGSLGALAGAALMPTGLARAHAIGPGGGRIDFHHHYFSPAWVRLVESKHKVQPVLGFDQFKSWT
IARDLEAMDRGNVEKAFLSVTQPGVWFGNVEESRRAARDMNDFAATMKSDHKGRYGQFAVLPLPDIDATLKEIEYAFDTL
KADGVGLLSSYGDKWLGDKSFWPVWEELNRRKAVVYIHATAPGCCAWEFQPGILPTFVELGSDLARAMVSLVQGGTAKAT
PDIKYIWSHGGGSIWAQRFLVGETAASLAREAPADSRLYQFRRFYYDTAAAADAIHMGILKMVVPPSQIVFGSDYPWVEP
AKIATGLEASGLSPQVLQAVYRDNAFRVMPQLREQLAAAARTN

Sequences:

>Translated_363_residues
MHTHCDHDGCQSRRHFLGSLGALAGAALMPTGLARAHAIGPGGGRIDFHHHYFSPAWVRLVESKHKVQPVLGFDQFKSWT
IARDLEAMDRGNVEKAFLSVTQPGVWFGNVEESRRAARDMNDFAATMKSDHKGRYGQFAVLPLPDIDATLKEIEYAFDTL
KADGVGLLSSYGDKWLGDKSFWPVWEELNRRKAVVYIHATAPGCCAWEFQPGILPTFVELGSDLARAMVSLVQGGTAKAT
PDIKYIWSHGGGSIWAQRFLVGETAASLAREAPADSRLYQFRRFYYDTAAAADAIHMGILKMVVPPSQIVFGSDYPWVEP
AKIATGLEASGLSPQVLQAVYRDNAFRVMPQLREQLAAAARTN
>Mature_363_residues
MHTHCDHDGCQSRRHFLGSLGALAGAALMPTGLARAHAIGPGGGRIDFHHHYFSPAWVRLVESKHKVQPVLGFDQFKSWT
IARDLEAMDRGNVEKAFLSVTQPGVWFGNVEESRRAARDMNDFAATMKSDHKGRYGQFAVLPLPDIDATLKEIEYAFDTL
KADGVGLLSSYGDKWLGDKSFWPVWEELNRRKAVVYIHATAPGCCAWEFQPGILPTFVELGSDLARAMVSLVQGGTAKAT
PDIKYIWSHGGGSIWAQRFLVGETAASLAREAPADSRLYQFRRFYYDTAAAADAIHMGILKMVVPPSQIVFGSDYPWVEP
AKIATGLEASGLSPQVLQAVYRDNAFRVMPQLREQLAAAARTN

Specific function: Unknown

COG id: COG2159

COG function: function code R; Predicted metal-dependent hydrolase of the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109715856, Length=320, Percent_Identity=21.875, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40007; Mature: 40007

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTHCDHDGCQSRRHFLGSLGALAGAALMPTGLARAHAIGPGGGRIDFHHHYFSPAWVRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHHHH
VESKHKVQPVLGFDQFKSWTIARDLEAMDRGNVEKAFLSVTQPGVWFGNVEESRRAARDM
HHHHHHCCHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEECCHHHHHHHHHHH
NDFAATMKSDHKGRYGQFAVLPLPDIDATLKEIEYAFDTLKADGVGLLSSYGDKWLGDKS
HHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC
FWPVWEELNRRKAVVYIHATAPGCCAWEFQPGILPTFVELGSDLARAMVSLVQGGTAKAT
CCHHHHHCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIKYIWSHGGGSIWAQRFLVGETAASLAREAPADSRLYQFRRFYYDTAAAADAIHMGIL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KMVVPPSQIVFGSDYPWVEPAKIATGLEASGLSPQVLQAVYRDNAFRVMPQLREQLAAAA
HHHCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
RTN
CCC
>Mature Secondary Structure
MHTHCDHDGCQSRRHFLGSLGALAGAALMPTGLARAHAIGPGGGRIDFHHHYFSPAWVRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHHHH
VESKHKVQPVLGFDQFKSWTIARDLEAMDRGNVEKAFLSVTQPGVWFGNVEESRRAARDM
HHHHHHCCHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEECCHHHHHHHHHHH
NDFAATMKSDHKGRYGQFAVLPLPDIDATLKEIEYAFDTLKADGVGLLSSYGDKWLGDKS
HHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCC
FWPVWEELNRRKAVVYIHATAPGCCAWEFQPGILPTFVELGSDLARAMVSLVQGGTAKAT
CCHHHHHCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIKYIWSHGGGSIWAQRFLVGETAASLAREAPADSRLYQFRRFYYDTAAAADAIHMGIL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KMVVPPSQIVFGSDYPWVEPAKIATGLEASGLSPQVLQAVYRDNAFRVMPQLREQLAAAA
HHHCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
RTN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA