Click here to switch to the map view.

The map label for this gene is aidB [H]

Identifier: 73539259

GI number: 73539259

Start: 2227330

End: 2229123

Strand: Direct

Name: aidB [H]

Synonym: Reut_B5437

Alternate gene names: 73539259

Gene position: 2227330-2229123 (Clockwise)

Preceding gene: 73539257

Following gene: 73539260

Centisome position: 81.7

GC content: 69.29

Gene sequence:

>1794_bases
ATGACCAGTGCTGTGCGCCATGCTGCCCCTCATGCCCCCGTTGTATCGCCGGCGGAGCACCCCGTGCCCGACCGCAAGGG
CGGCAGCCTGTACACCGCCGATCCGGATCTGCGCGCGCTGCTGCCGCTTTACCTGCCGGCGGACTTGCTGAACCTGCTGC
AGCCGCATCTGGAGCGCATGGGCGAACTGGCTGGCGGCGTGCTGGACGAACTGGCCCTGACCGCCGACCAGAACCCGCCG
ACGCTGACCCACCGTACCCGCAGCGGCATCGACCAGCAACGCGTGCACAAGCATCCCGCCTACGTCGAACTGGAGCGCGT
GGCGTTCTCCGAGTTCGGGCTCGCTGCGGTCTCGCACCGCGGCGGTGTGTTCGGCTGGGACAAGCCGATGCCGCCGGCAG
CCAAGTACGCACTCACGTATATGCTGGTGCAGGCCGAGTTCGGCCTGTGCTGCCCGCTGTCGATGACCGATTCGCTGACG
CGCACGCTGCGCAAGTTCGGCGATCCGGCACTGGTCGAGAAGTTCTTGCCGAACCTGACCACGCAGGTGTTCGAAGACCT
GTACCAGGGCGCGATGTTCATGACAGAGCAGGGCGCGGGCTCCGACGTGGCCGCGACCGCGACCCGCGCCATGCGCGATC
CGCAGGCCGAAGGCGGCTGGCGTCTGAGTGGCGACAAGTGGTTCTGCTCGAATCCCGACGCCGCGCTGGCGATGGTGCTG
GCGCGTGTGGAAGACGAAGCCGGCAACGCTGTGCCCGGCCACAAGGGCGTGTCGCTGTTCCTGCTGCCGCGCACGCTGTC
CGACGGCAGCGCCAACCAGTACCGCATCATCCGCCTGAAGGACAAGCTCGGCACGCGCTCGATGGCCAGTGGTGAAATCC
GGCTGGAAGGCGCAAGCGCCTACCTGGTCGGCGAACTCGGCCGCGGCTTCGTGCAGATGGCCGACATGATCAACAACTCG
CGCCTGTCCAACGGCGTGCGCGCCGCCGGCCTGATGCGCCGCGCATTGACCGAGGGCCTGTTCATCGCCCACGAGCGCAA
GGCCTTCGGCAAGCGCCTCGAAGACATGCCGCTGATGCGCCGCCAGCTCCTGAAGCTCACGCTGCCGACCGAGCAGGCGC
GCACCATGGTGTTCCAGACCGCCGAAGCACTGCGCCGCGCCGACGCCGGCGAGGACGGCGCCTATCCGCTGATGCGCATC
CTCACGCCCCTGATCAAGTTCCGCGCGTGCCGTGACGCACGCAAGGTCACCGGCGATGCCATGGAAATCCGCGGCGGCTG
CGGCTACATCGAAGAATGGAGCGATGCGCGCCTCGTGCGCGACGCCCACCTCGGCTCGATCTGGGAAGGCACCAGCAATA
TCGTCGCACTCGACGTCCTGCGTGCGATCCGCCGCGAGGGCTCGCTACCCGCGCTGCGCGCGCACCTGTCCGGCTTGCTG
GCCGATACGCCGCTGCATCCGACCGCCCGCGCCACCTTCGAAGCCGCCATCGAACGCGCTGCGGCTTTCGCCGCCAGCGC
GGCCGAAGCCGGTGCCGAAGGCGACCTCCTGGCCCGCCAGGCTGCCTCTGGCCTGTACAACGTCACGACCGCCGTGGCGA
TGGCCTGGGAAGCCGGGCGCATCGGCTCGGTGCGCCGCATGCGGCTCGCGCAGCTCGTGCTGCGCCACCGCGTGCTGCCG
CAAGACCCGCTGTCCGGCCAGGCCGAGCCGGAATGGCTCGCCGAGACCGTGGCACCGCCTGCCGACGGTACCGTGCGCGC
AGCCGGTGCGGTCGATCAGGTCAACGTGTTCTGA

Upstream 100 bases:

>100_bases
TAGACGCGAATCCATGGGAATCCAATAATGGTGCAAACAGGTCCGCGCGCCGGCAAGCCAGCCCGGCGAATGGCGGGCCA
GCCCAATCCAGGAGACCCAG

Downstream 100 bases:

>100_bases
CCCTTCTCCAGCTTCACCCGACATCAGCCCCCGGTGGCACCGCAACCCGGTGCCGCCCACCGCATCGCCCGACATCCCCC
GGGGCAATGCGAGACGACCC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MTSAVRHAAPHAPVVSPAEHPVPDRKGGSLYTADPDLRALLPLYLPADLLNLLQPHLERMGELAGGVLDELALTADQNPP
TLTHRTRSGIDQQRVHKHPAYVELERVAFSEFGLAAVSHRGGVFGWDKPMPPAAKYALTYMLVQAEFGLCCPLSMTDSLT
RTLRKFGDPALVEKFLPNLTTQVFEDLYQGAMFMTEQGAGSDVAATATRAMRDPQAEGGWRLSGDKWFCSNPDAALAMVL
ARVEDEAGNAVPGHKGVSLFLLPRTLSDGSANQYRIIRLKDKLGTRSMASGEIRLEGASAYLVGELGRGFVQMADMINNS
RLSNGVRAAGLMRRALTEGLFIAHERKAFGKRLEDMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGEDGAYPLMRI
LTPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPALRAHLSGLL
ADTPLHPTARATFEAAIERAAAFAASAAEAGAEGDLLARQAASGLYNVTTAVAMAWEAGRIGSVRRMRLAQLVLRHRVLP
QDPLSGQAEPEWLAETVAPPADGTVRAAGAVDQVNVF

Sequences:

>Translated_597_residues
MTSAVRHAAPHAPVVSPAEHPVPDRKGGSLYTADPDLRALLPLYLPADLLNLLQPHLERMGELAGGVLDELALTADQNPP
TLTHRTRSGIDQQRVHKHPAYVELERVAFSEFGLAAVSHRGGVFGWDKPMPPAAKYALTYMLVQAEFGLCCPLSMTDSLT
RTLRKFGDPALVEKFLPNLTTQVFEDLYQGAMFMTEQGAGSDVAATATRAMRDPQAEGGWRLSGDKWFCSNPDAALAMVL
ARVEDEAGNAVPGHKGVSLFLLPRTLSDGSANQYRIIRLKDKLGTRSMASGEIRLEGASAYLVGELGRGFVQMADMINNS
RLSNGVRAAGLMRRALTEGLFIAHERKAFGKRLEDMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGEDGAYPLMRI
LTPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPALRAHLSGLL
ADTPLHPTARATFEAAIERAAAFAASAAEAGAEGDLLARQAASGLYNVTTAVAMAWEAGRIGSVRRMRLAQLVLRHRVLP
QDPLSGQAEPEWLAETVAPPADGTVRAAGAVDQVNVF
>Mature_596_residues
TSAVRHAAPHAPVVSPAEHPVPDRKGGSLYTADPDLRALLPLYLPADLLNLLQPHLERMGELAGGVLDELALTADQNPPT
LTHRTRSGIDQQRVHKHPAYVELERVAFSEFGLAAVSHRGGVFGWDKPMPPAAKYALTYMLVQAEFGLCCPLSMTDSLTR
TLRKFGDPALVEKFLPNLTTQVFEDLYQGAMFMTEQGAGSDVAATATRAMRDPQAEGGWRLSGDKWFCSNPDAALAMVLA
RVEDEAGNAVPGHKGVSLFLLPRTLSDGSANQYRIIRLKDKLGTRSMASGEIRLEGASAYLVGELGRGFVQMADMINNSR
LSNGVRAAGLMRRALTEGLFIAHERKAFGKRLEDMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGEDGAYPLMRIL
TPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPALRAHLSGLLA
DTPLHPTARATFEAAIERAAAFAASAAEAGAEGDLLARQAASGLYNVTTAVAMAWEAGRIGSVRRMRLAQLVLRHRVLPQ
DPLSGQAEPEWLAETVAPPADGTVRAAGAVDQVNVF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=329, Percent_Identity=28.2674772036474, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI226958414, Length=313, Percent_Identity=26.8370607028754, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226958412, Length=313, Percent_Identity=26.8370607028754, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI21361497, Length=309, Percent_Identity=26.2135922330097, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI4557233, Length=284, Percent_Identity=29.2253521126761, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=356, Percent_Identity=26.4044943820225, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=356, Percent_Identity=26.4044943820225, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI4501857, Length=309, Percent_Identity=28.1553398058252, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187960098, Length=300, Percent_Identity=29, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557231, Length=300, Percent_Identity=29, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7656849, Length=328, Percent_Identity=24.6951219512195, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082384, Length=418, Percent_Identity=34.9282296650718, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87081958, Length=338, Percent_Identity=26.3313609467456, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=510, Percent_Identity=30, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI86563381, Length=510, Percent_Identity=30, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=286, Percent_Identity=26.5734265734266, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=299, Percent_Identity=27.0903010033445, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=360, Percent_Identity=30, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=435, Percent_Identity=27.816091954023, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=364, Percent_Identity=25.2747252747253, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=271, Percent_Identity=26.9372693726937, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=214, Percent_Identity=25.2336448598131, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=314, Percent_Identity=24.5222929936306, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=198, Percent_Identity=29.7979797979798, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=274, Percent_Identity=25.5474452554745, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=297, Percent_Identity=22.8956228956229, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=272, Percent_Identity=26.1029411764706, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=319, Percent_Identity=23.5109717868339, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355753, Length=308, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363737, Length=308, Percent_Identity=25, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356377, Length=319, Percent_Identity=26.6457680250784, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646207, Length=277, Percent_Identity=25.2707581227437, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=299, Percent_Identity=29.0969899665552, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 64700; Mature: 64569

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAVRHAAPHAPVVSPAEHPVPDRKGGSLYTADPDLRALLPLYLPADLLNLLQPHLERM
CCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELAGGVLDELALTADQNPPTLTHRTRSGIDQQRVHKHPAYVELERVAFSEFGLAAVSHR
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHCCCCCEEHHHHHHHHHCHHHHHCC
GGVFGWDKPMPPAAKYALTYMLVQAEFGLCCPLSMTDSLTRTLRKFGDPALVEKFLPNLT
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
TQVFEDLYQGAMFMTEQGAGSDVAATATRAMRDPQAEGGWRLSGDKWFCSNPDAALAMVL
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHH
ARVEDEAGNAVPGHKGVSLFLLPRTLSDGSANQYRIIRLKDKLGTRSMASGEIRLEGASA
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCE
YLVGELGRGFVQMADMINNSRLSNGVRAAGLMRRALTEGLFIAHERKAFGKRLEDMPLMR
EEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCHHHH
RQLLKLTLPTEQARTMVFQTAEALRRADAGEDGAYPLMRILTPLIKFRACRDARKVTGDA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
MEIRGGCGYIEEWSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPALRAHLSGLL
HEECCCCCCHHCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ADTPLHPTARATFEAAIERAAAFAASAAEAGAEGDLLARQAASGLYNVTTAVAMAWEAGR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
IGSVRRMRLAQLVLRHRVLPQDPLSGQAEPEWLAETVAPPADGTVRAAGAVDQVNVF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
TSAVRHAAPHAPVVSPAEHPVPDRKGGSLYTADPDLRALLPLYLPADLLNLLQPHLERM
CCCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GELAGGVLDELALTADQNPPTLTHRTRSGIDQQRVHKHPAYVELERVAFSEFGLAAVSHR
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHCCCCCEEHHHHHHHHHCHHHHHCC
GGVFGWDKPMPPAAKYALTYMLVQAEFGLCCPLSMTDSLTRTLRKFGDPALVEKFLPNLT
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
TQVFEDLYQGAMFMTEQGAGSDVAATATRAMRDPQAEGGWRLSGDKWFCSNPDAALAMVL
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHH
ARVEDEAGNAVPGHKGVSLFLLPRTLSDGSANQYRIIRLKDKLGTRSMASGEIRLEGASA
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCE
YLVGELGRGFVQMADMINNSRLSNGVRAAGLMRRALTEGLFIAHERKAFGKRLEDMPLMR
EEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCHHHH
RQLLKLTLPTEQARTMVFQTAEALRRADAGEDGAYPLMRILTPLIKFRACRDARKVTGDA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
MEIRGGCGYIEEWSDARLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPALRAHLSGLL
HEECCCCCCHHCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ADTPLHPTARATFEAAIERAAAFAASAAEAGAEGDLLARQAASGLYNVTTAVAMAWEAGR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
IGSVRRMRLAQLVLRHRVLPQDPLSGQAEPEWLAETVAPPADGTVRAAGAVDQVNVF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]