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The map label for this gene is exaA [H]

Identifier: 73539241

GI number: 73539241

Start: 2206483

End: 2208213

Strand: Reverse

Name: exaA [H]

Synonym: Reut_B5419

Alternate gene names: 73539241

Gene position: 2208213-2206483 (Counterclockwise)

Preceding gene: 73539243

Following gene: 73539240

Centisome position: 81.0

GC content: 64.18

Gene sequence:

>1731_bases
ATGCTCTCTGTCCCTCGCCTCTCCCGGCAAGCCCTTCCCCTGCTGCTCCTGGCCCTGTTTGCGTCCGCCGCGTACGGCGC
CGACGAGATCCAGGGCGGCGCGACCACCGCTGGTGCGCCGATGTCCAGTGCGCTGCGTCCCGTCACGCAGGCGCAACTCG
ACGGGGCGCTCACGAGCAGCAATGACTGGCTGCATTCGAACGGGTCGTACGGCCAGACGCGCTATTACGCGGGCACCCAG
ATCAACACGAAGAACGTCGCCAAGCTCCGGCCCGCGTTCGTGTTCCAGACCGCGGTGATGGAGTCGATGGAAACCGCGCC
GATCGTCGTCAACGGCGTGATGTTCCTCACGACCTCGTACAACCACGTCTACGCGGTGGACGCGGTGACCGGCAAGGAGT
TCTGGCACTACAAGCACAAGATGGGCCCGGTCACGACCTTCTGCTGCGGCCCGAACAACCGCGGCGTGGCCATTAGCGGC
GACCGTCTCTACATGGGAACGCTCGACGCGAAGCTGGTTTCGCTCGATGCGAAGACGGGCAAGCTGCTGTGGGAAACGCA
GATTGCCGATCCTGAACTGGGCTATTCGGAAACCATGGCGCCGGTCGTGGTCGACGACAAGATCCTGATCGGCACGAATG
GCGGCGAATACGGCATCCGCGGCTTCGTCAAGGCCTTCAGCGCCAACGACGGCAAGCTGCTGTGGACCTTCTATACGATC
CCCGACAAGGGCCATGAAGGTGTCTGGGCCACCAAGGACGCCACCGGCCGCGACATGAAGCGCAATATCGCCGCGGAAAA
GAAGATGCTTTCCGACAAGGGCGGCGACTTCTACAAGACGCTCGGCGGCGGCGTGTGGATGGCCCCGGCCGTTGACCGCG
CCAACAAGCTGGTGATCTTCGTGGTCGGCAACCCGTCGCCGGACCTGTATGGCGCGATTCGCCCGGGCGACAACCTGTAC
ACCGACTCGATGGTCGCGGTCGATCTCAACACCGGCGCGTACAAGTGGCATTCGCAATATATCGCCCATGACGTCTGGGA
CCTGGACGCCGTGAGCCCGCCGATCCTGGTCGACGTGCGCGATGAAAAGGGCAACATGATTCCCGGCGTGATCCATGGCG
GCAAGACCGGGCACGTCTACGTGCATGACCGCCGCGACGGGCGCCTGATCCGCTTCTCGGACGCGATGATCCCGCAGGAA
AACATGTGGACGCTGCCAACCGCGCAAGGCGCACGCATGCTGCCCGGCGCCAACGGCGGCGTGGAATGGTCACCGATGGC
GTTCAACCCGAAGCTGCGCCTGGTCTATGCCGCCAACCTGCACCAGCCGATGACGTACCAGGTGGAAGACGCACCGTACC
CGGGCGGCAAGCTTTGGCTCGGCGGCGCGTTCAAGACGATCCCGAGCGAGCAGCAGTGGGGCAAGCTGTCGGCGGTCAAT
ATCGACACCGGCAAGGTAAAGTGGGACTTCAAGACCGAGCAACCGCTCATTGGCGGCGTGCTGGCGACCGCTGGCGGGCT
GGTGTTCAACGGGGAAGGCAATGGCTGGTTCCGCGCCTTTGACGCAGCCACCGGCAAGAAGCTGTGGGAATTCCAGTGCG
GCGCGGGCGTCAACGCGCCGGCGGTGTCCTACATGGTCGGCGGCAAGCAGTACATCGCCGTGGCAGCGGGCGGCAATACG
CAGCTCGACTTCAAGCGCGGTAACAGCGTGTTCGTCTTTGCCGTGCAATAA

Upstream 100 bases:

>100_bases
GGCCAGTCTGTGCGCCGCGCCGATGCCGGCCCGCGCGCCGCGATCCGGCGCACGAGGCTGGCGCCACCGGGGCTACAAGA
TTCGAAGAAAAGGAGCGACC

Downstream 100 bases:

>100_bases
CGCGATCATCGACGGGGGCACCATGGCAGGCGTCAGCCCGGTTCCAGCGCGGCGCCTGCCCGCGCTGATGCTGTTGCTAT
CCCTCTGCGGCGTGGCCGGC

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MLSVPRLSRQALPLLLLALFASAAYGADEIQGGATTAGAPMSSALRPVTQAQLDGALTSSNDWLHSNGSYGQTRYYAGTQ
INTKNVAKLRPAFVFQTAVMESMETAPIVVNGVMFLTTSYNHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISG
DRLYMGTLDAKLVSLDAKTGKLLWETQIADPELGYSETMAPVVVDDKILIGTNGGEYGIRGFVKAFSANDGKLLWTFYTI
PDKGHEGVWATKDATGRDMKRNIAAEKKMLSDKGGDFYKTLGGGVWMAPAVDRANKLVIFVVGNPSPDLYGAIRPGDNLY
TDSMVAVDLNTGAYKWHSQYIAHDVWDLDAVSPPILVDVRDEKGNMIPGVIHGGKTGHVYVHDRRDGRLIRFSDAMIPQE
NMWTLPTAQGARMLPGANGGVEWSPMAFNPKLRLVYAANLHQPMTYQVEDAPYPGGKLWLGGAFKTIPSEQQWGKLSAVN
IDTGKVKWDFKTEQPLIGGVLATAGGLVFNGEGNGWFRAFDAATGKKLWEFQCGAGVNAPAVSYMVGGKQYIAVAAGGNT
QLDFKRGNSVFVFAVQ

Sequences:

>Translated_576_residues
MLSVPRLSRQALPLLLLALFASAAYGADEIQGGATTAGAPMSSALRPVTQAQLDGALTSSNDWLHSNGSYGQTRYYAGTQ
INTKNVAKLRPAFVFQTAVMESMETAPIVVNGVMFLTTSYNHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISG
DRLYMGTLDAKLVSLDAKTGKLLWETQIADPELGYSETMAPVVVDDKILIGTNGGEYGIRGFVKAFSANDGKLLWTFYTI
PDKGHEGVWATKDATGRDMKRNIAAEKKMLSDKGGDFYKTLGGGVWMAPAVDRANKLVIFVVGNPSPDLYGAIRPGDNLY
TDSMVAVDLNTGAYKWHSQYIAHDVWDLDAVSPPILVDVRDEKGNMIPGVIHGGKTGHVYVHDRRDGRLIRFSDAMIPQE
NMWTLPTAQGARMLPGANGGVEWSPMAFNPKLRLVYAANLHQPMTYQVEDAPYPGGKLWLGGAFKTIPSEQQWGKLSAVN
IDTGKVKWDFKTEQPLIGGVLATAGGLVFNGEGNGWFRAFDAATGKKLWEFQCGAGVNAPAVSYMVGGKQYIAVAAGGNT
QLDFKRGNSVFVFAVQ
>Mature_576_residues
MLSVPRLSRQALPLLLLALFASAAYGADEIQGGATTAGAPMSSALRPVTQAQLDGALTSSNDWLHSNGSYGQTRYYAGTQ
INTKNVAKLRPAFVFQTAVMESMETAPIVVNGVMFLTTSYNHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISG
DRLYMGTLDAKLVSLDAKTGKLLWETQIADPELGYSETMAPVVVDDKILIGTNGGEYGIRGFVKAFSANDGKLLWTFYTI
PDKGHEGVWATKDATGRDMKRNIAAEKKMLSDKGGDFYKTLGGGVWMAPAVDRANKLVIFVVGNPSPDLYGAIRPGDNLY
TDSMVAVDLNTGAYKWHSQYIAHDVWDLDAVSPPILVDVRDEKGNMIPGVIHGGKTGHVYVHDRRDGRLIRFSDAMIPQE
NMWTLPTAQGARMLPGANGGVEWSPMAFNPKLRLVYAANLHQPMTYQVEDAPYPGGKLWLGGAFKTIPSEQQWGKLSAVN
IDTGKVKWDFKTEQPLIGGVLATAGGLVFNGEGNGWFRAFDAATGKKLWEFQCGAGVNAPAVSYMVGGKQYIAVAAGGNT
QLDFKRGNSVFVFAVQ

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=679, Percent_Identity=23.4167893961708, Blast_Score=172, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 62331; Mature: 62331

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVPRLSRQALPLLLLALFASAAYGADEIQGGATTAGAPMSSALRPVTQAQLDGALTSS
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHCHHHHHHHCCCEECC
NDWLHSNGSYGQTRYYAGTQINTKNVAKLRPAFVFQTAVMESMETAPIVVNGVMFLTTSY
CCEEECCCCCCCEEEEECCEECCCCHHHCCHHHHHHHHHHHHCCCCCEEEEEEEEEEECC
NHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISGDRLYMGTLDAKLVSLDAKTG
CEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCEEEECCEEEEEECCEEEEEEECCCC
KLLWETQIADPELGYSETMAPVVVDDKILIGTNGGEYGIRGFVKAFSANDGKLLWTFYTI
CEEEEEECCCCCCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHEECCCCCEEEEEEEEC
PDKGHEGVWATKDATGRDMKRNIAAEKKMLSDKGGDFYKTLGGGVWMAPAVDRANKLVIF
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEECCCCCCCCEEEEE
VVGNPSPDLYGAIRPGDNLYTDSMVAVDLNTGAYKWHSQYIAHDVWDLDAVSPPILVDVR
EECCCCCCEEEEECCCCCEECCCEEEEEECCCEEEEHHHHHHHCCCCCCCCCCCEEEEEE
DEKGNMIPGVIHGGKTGHVYVHDRRDGRLIRFSDAMIPQENMWTLPTAQGARMLPGANGG
CCCCCCCCEEEECCCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCEECCCCCCC
VEWSPMAFNPKLRLVYAANLHQPMTYQVEDAPYPGGKLWLGGAFKTIPSEQQWGKLSAVN
EEECCEEECCCEEEEEEECCCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHCCCEEEEE
IDTGKVKWDFKTEQPLIGGVLATAGGLVFNGEGNGWFRAFDAATGKKLWEFQCGAGVNAP
ECCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEEECCCCCCCC
AVSYMVGGKQYIAVAAGGNTQLDFKRGNSVFVFAVQ
EEEEEECCCEEEEEEECCCEEEEEECCCEEEEEEEC
>Mature Secondary Structure
MLSVPRLSRQALPLLLLALFASAAYGADEIQGGATTAGAPMSSALRPVTQAQLDGALTSS
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHCHHHHHHHCCCEECC
NDWLHSNGSYGQTRYYAGTQINTKNVAKLRPAFVFQTAVMESMETAPIVVNGVMFLTTSY
CCEEECCCCCCCEEEEECCEECCCCHHHCCHHHHHHHHHHHHCCCCCEEEEEEEEEEECC
NHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISGDRLYMGTLDAKLVSLDAKTG
CEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCEEEECCEEEEEECCEEEEEEECCCC
KLLWETQIADPELGYSETMAPVVVDDKILIGTNGGEYGIRGFVKAFSANDGKLLWTFYTI
CEEEEEECCCCCCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHEECCCCCEEEEEEEEC
PDKGHEGVWATKDATGRDMKRNIAAEKKMLSDKGGDFYKTLGGGVWMAPAVDRANKLVIF
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEECCCCCCCCEEEEE
VVGNPSPDLYGAIRPGDNLYTDSMVAVDLNTGAYKWHSQYIAHDVWDLDAVSPPILVDVR
EECCCCCCEEEEECCCCCEECCCEEEEEECCCEEEEHHHHHHHCCCCCCCCCCCEEEEEE
DEKGNMIPGVIHGGKTGHVYVHDRRDGRLIRFSDAMIPQENMWTLPTAQGARMLPGANGG
CCCCCCCCEEEECCCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCEECCCCCCC
VEWSPMAFNPKLRLVYAANLHQPMTYQVEDAPYPGGKLWLGGAFKTIPSEQQWGKLSAVN
EEECCEEECCCEEEEEEECCCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHCCCEEEEE
IDTGKVKWDFKTEQPLIGGVLATAGGLVFNGEGNGWFRAFDAATGKKLWEFQCGAGVNAP
ECCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEEEEEECCCCCCCC
AVSYMVGGKQYIAVAAGGNTQLDFKRGNSVFVFAVQ
EEEEEECCCEEEEEEECCCEEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]