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The map label for this gene is mmgC [H]

Identifier: 73539108

GI number: 73539108

Start: 2045908

End: 2047080

Strand: Reverse

Name: mmgC [H]

Synonym: Reut_B5285

Alternate gene names: 73539108

Gene position: 2047080-2045908 (Counterclockwise)

Preceding gene: 73539109

Following gene: 73539107

Centisome position: 75.09

GC content: 60.19

Gene sequence:

>1173_bases
ATGGACTGCAACGATATGATGAATTTTGCGTTGCCGGAAGAACTGCGCATGCTGAAGGATTCGCTGCGCCGCTTTGTGAA
TCAGGAACTCATTCCGGCTGAACTCACCGCACGCAAGGACGACAAGCTGATTCCGGAACTGCGTGCCCGCGTCGAGGCGT
TCGGGCAAGAACTGGGACTCGACAAGTTCGATGTTCCGGTCGAGTACGGCGGGCTGGGCTTCGGCCTGCTCGCCAAGACA
ATCGTGTGGTCCGAGCTTGCCCGCACGGTGGCCTTGCCGGTGCGGTCAATCAATCCGTTCGGCGCGACGGTGTACCCCGT
GCTCTATGAACTCGACGCTGCGCAGAAGGAGCGCTTTCTCTTGCCGACATTGCGCGGCGAATTGAAATGGTGTTTTGCCC
AGACCGAGCCCGATGCGGGTTCGGACCCCGGCGGCATGAAGACCACCGCCGTGCGCGACGGCGATCATTACGTGATCAAC
GGTTTCAAGCGCTTCATCACCGGTGCGGCGGATGCCGATTATGCGCAACTGATGGCCGCGACGGATCGCACAAAAGGCTC
GCACGGCGGGATCTCTGCCTTCATCGTCGACATGAAATCTCCCGGCGTCAAACTGCTGCGTGCGCAGAAGATGCTGGTCG
ACGACACGCCCTGGGAGATCGCCTTCGACGATGTCAGAGTGCCGCTCGAAAATCGCATCGGCGCCGAAGGCGAAGGCTTC
AGGCACGCACAGAAGGTGCTCACCGTACTTCGCGTGCGTCACGGCGCCAGGGCCTGCGGAGTGATGGAGCGCTGTCTCGA
ACTGGCCGCAAGCTACGCGAAGGAGCGTGTGACTTTCGACAAGCCGCTTGCCGAACGGCAAGGCGTGCAATGGTTGATCG
CCGACTCCTACCTCGAGTGGCACCAGCTCGAACTGATGGTCAGGAACGCAGCGTGGAAACACGATCGCGGCGAGGACATT
CGCACGGAAGCTTACATGGCGAAGAATTTCGGCGACAGCAAATCCTTTGAAGCTGCAGATCGATGCATGCAACTTCACGG
CGGTATCGGACTCTCGACCGAACTGCCGATCGAGAAGTTCTGGCGTGATCAGCGCAGCATGCTGATCACCGATGGGCCGA
CCGACGTTCTCAAGGGCGCCATCGCCCGGCATGCCTTGAATGTGTTCGGCTGA

Upstream 100 bases:

>100_bases
AATCGAATTCATCGCGCTGAGCGCTGCCAGCACGGCCAACAGCAGCCGCGTGCACGCATGTCGCCATGCGCGCACGCAGC
GGCACTCAAAGGAAATGGGT

Downstream 100 bases:

>100_bases
TGACACTGGTCCGCCGAGACGCATTGCCGGTTCAGGCAATGCGTCGCGACTGAATCTGTTCCTTTTGGAGAACCCATGAA
TCCAAGCCGCATCCACGAAC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MDCNDMMNFALPEELRMLKDSLRRFVNQELIPAELTARKDDKLIPELRARVEAFGQELGLDKFDVPVEYGGLGFGLLAKT
IVWSELARTVALPVRSINPFGATVYPVLYELDAAQKERFLLPTLRGELKWCFAQTEPDAGSDPGGMKTTAVRDGDHYVIN
GFKRFITGAADADYAQLMAATDRTKGSHGGISAFIVDMKSPGVKLLRAQKMLVDDTPWEIAFDDVRVPLENRIGAEGEGF
RHAQKVLTVLRVRHGARACGVMERCLELAASYAKERVTFDKPLAERQGVQWLIADSYLEWHQLELMVRNAAWKHDRGEDI
RTEAYMAKNFGDSKSFEAADRCMQLHGGIGLSTELPIEKFWRDQRSMLITDGPTDVLKGAIARHALNVFG

Sequences:

>Translated_390_residues
MDCNDMMNFALPEELRMLKDSLRRFVNQELIPAELTARKDDKLIPELRARVEAFGQELGLDKFDVPVEYGGLGFGLLAKT
IVWSELARTVALPVRSINPFGATVYPVLYELDAAQKERFLLPTLRGELKWCFAQTEPDAGSDPGGMKTTAVRDGDHYVIN
GFKRFITGAADADYAQLMAATDRTKGSHGGISAFIVDMKSPGVKLLRAQKMLVDDTPWEIAFDDVRVPLENRIGAEGEGF
RHAQKVLTVLRVRHGARACGVMERCLELAASYAKERVTFDKPLAERQGVQWLIADSYLEWHQLELMVRNAAWKHDRGEDI
RTEAYMAKNFGDSKSFEAADRCMQLHGGIGLSTELPIEKFWRDQRSMLITDGPTDVLKGAIARHALNVFG
>Mature_390_residues
MDCNDMMNFALPEELRMLKDSLRRFVNQELIPAELTARKDDKLIPELRARVEAFGQELGLDKFDVPVEYGGLGFGLLAKT
IVWSELARTVALPVRSINPFGATVYPVLYELDAAQKERFLLPTLRGELKWCFAQTEPDAGSDPGGMKTTAVRDGDHYVIN
GFKRFITGAADADYAQLMAATDRTKGSHGGISAFIVDMKSPGVKLLRAQKMLVDDTPWEIAFDDVRVPLENRIGAEGEGF
RHAQKVLTVLRVRHGARACGVMERCLELAASYAKERVTFDKPLAERQGVQWLIADSYLEWHQLELMVRNAAWKHDRGEDI
RTEAYMAKNFGDSKSFEAADRCMQLHGGIGLSTELPIEKFWRDQRSMLITDGPTDVLKGAIARHALNVFG

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=386, Percent_Identity=34.1968911917098, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI4501859, Length=387, Percent_Identity=28.6821705426357, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI187960098, Length=389, Percent_Identity=29.8200514138817, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4557231, Length=389, Percent_Identity=29.8200514138817, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=28.125, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI211971008, Length=283, Percent_Identity=34.982332155477, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI48976061, Length=283, Percent_Identity=34.982332155477, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI226958412, Length=388, Percent_Identity=29.1237113402062, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI21361497, Length=399, Percent_Identity=29.0726817042606, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=30.4812834224599, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI38505218, Length=383, Percent_Identity=28.7206266318538, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4557235, Length=337, Percent_Identity=29.3768545994065, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=29.3768545994065, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226958414, Length=335, Percent_Identity=29.8507462686567, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4503943, Length=365, Percent_Identity=24.6575342465753, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI7669494, Length=288, Percent_Identity=27.4305555555556, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=29.9479166666667, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=28.3116883116883, Blast_Score=149, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=32.2997416020672, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=31.2169312169312, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17534899, Length=389, Percent_Identity=31.8766066838046, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=30.6701030927835, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=31.0344827586207, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17533517, Length=337, Percent_Identity=28.1899109792285, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=279, Percent_Identity=34.0501792114695, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71985184, Length=360, Percent_Identity=30.8333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=27.390180878553, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=30.2491103202847, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=28.1081081081081, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=334, Percent_Identity=29.940119760479, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=31.5126050420168, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=26.790450928382, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71985192, Length=306, Percent_Identity=30.3921568627451, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=28.8321167883212, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356377, Length=388, Percent_Identity=34.7938144329897, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=34.2857142857143, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24660351, Length=382, Percent_Identity=32.1989528795811, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=29.0666666666667, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281363737, Length=349, Percent_Identity=30.0859598853868, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355753, Length=395, Percent_Identity=29.1139240506329, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920834, Length=296, Percent_Identity=29.3918918918919, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43664; Mature: 43664

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCNDMMNFALPEELRMLKDSLRRFVNQELIPAELTARKDDKLIPELRARVEAFGQELGL
CCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCC
DKFDVPVEYGGLGFGLLAKTIVWSELARTVALPVRSINPFGATVYPVLYELDAAQKERFL
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHCCEE
LPTLRGELKWCFAQTEPDAGSDPGGMKTTAVRDGDHYVINGFKRFITGAADADYAQLMAA
CHHHHCCEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
TDRTKGSHGGISAFIVDMKSPGVKLLRAQKMLVDDTPWEIAFDDVRVPLENRIGAEGEGF
HHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCEECCHHHCCCCCCCCH
RHAQKVLTVLRVRHGARACGVMERCLELAASYAKERVTFDKPLAERQGVQWLIADSYLEW
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEHHHHHH
HQLELMVRNAAWKHDRGEDIRTEAYMAKNFGDSKSFEAADRCMQLHGGIGLSTELPIEKF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
WRDQRSMLITDGPTDVLKGAIARHALNVFG
HCCCCCEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDCNDMMNFALPEELRMLKDSLRRFVNQELIPAELTARKDDKLIPELRARVEAFGQELGL
CCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCC
DKFDVPVEYGGLGFGLLAKTIVWSELARTVALPVRSINPFGATVYPVLYELDAAQKERFL
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHCCEE
LPTLRGELKWCFAQTEPDAGSDPGGMKTTAVRDGDHYVINGFKRFITGAADADYAQLMAA
CHHHHCCEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
TDRTKGSHGGISAFIVDMKSPGVKLLRAQKMLVDDTPWEIAFDDVRVPLENRIGAEGEGF
HHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCEECCHHHCCCCCCCCH
RHAQKVLTVLRVRHGARACGVMERCLELAASYAKERVTFDKPLAERQGVQWLIADSYLEW
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEHHHHHH
HQLELMVRNAAWKHDRGEDIRTEAYMAKNFGDSKSFEAADRCMQLHGGIGLSTELPIEKF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
WRDQRSMLITDGPTDVLKGAIARHALNVFG
HCCCCCEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]