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The map label for this gene is siaT [H]

Identifier: 73539045

GI number: 73539045

Start: 1968766

End: 1970670

Strand: Reverse

Name: siaT [H]

Synonym: Reut_B5222

Alternate gene names: 73539045

Gene position: 1970670-1968766 (Counterclockwise)

Preceding gene: 73539046

Following gene: 73539044

Centisome position: 72.29

GC content: 66.56

Gene sequence:

>1905_bases
ATGTCCACGCATATGGTCGATATCAATCCCCCGGGCATAGAGTCCCATGCCGGGGCGCTTTCGGGCGGCGCACCGGCGCG
CACGCTGCGGCTGGCTGACAAGGCGCTCGGCGTTGTGTCCGAAGTGCCGGCGGCCCTGCTCGTGGTGGCCGAGATCGGCG
TGCTGTTCAGCGGCGTGCTGAGCCGCTATGTCCTGCACACGCCGCTGGTGTGGGTCGACGAGCTGGCGTCGCTGTTGTTC
ATCTGGCTCATCATGCTCGGCGCCGCGGTGGCGTTCCGGCGCGGCAGCCATATGCGCATGACGGCGCTCGTTGATGCCGC
AGCGCCGAAATGGCGCGGCGTGTTCGAACTCGTGGCAACGGTGGCGGCGCTGACGTGGCTCGTGCTGGTCGCGCATCCCG
CTTATGAATTCGCGAGTGAGGAAGCCGCCGTGACCATGCCGGCACTGGACATCTCCAACGCCTGGCGTGCCGCCGCGCTG
CCGCTCGGCATCGCGCTGATCCTGCTGATGAGCGTGGTGCGGCTGCTGTCCACCTCCAGCCTGCGAATGGTGTTGGTGGC
ACTGGTCGCATGCGCTGGGGTCGTGGGCGGCCTTGTGCTGCTGCAGCCTGCCTTGCAAGAACTCGGCAATGCCAACCTGC
TGGTGTTCTTTGTCGGCATCGTTGGCCTGCTGGTGTTCACGGGCGTGCCGATCGCATTCTCGTTCGGCCTAGCGACGTTC
GGCTATCTGTCGCTGACTACGTCCACGCCGACCATTGTCGTGATCGGCCGCATGGACGAAGGCATGTCGCACCTGATCCT
GCTCGCGGTGCCGATGTTCGTGTTCCTCGGCGTGCTGATCGAGATGACGTCGATGGCGCGCGCCATGGTGCAGTTCCTGG
CCAACCTGCTCGGCCATATCCGTGGCGGCCTGTCGTATGTGCTGATCGGGGCGATGTATCTCGTCTCCGGCATCTCGGGC
TCCAAGGCGGCGGACATGGCAGCCGTGGCGCCGGCGCTGTTTCCCGAGATGAAGAAGCGCGGCGCCGATGATGGCGACAT
GGTCGCGCTGCTTGCGGCGACCGGCGCGCAGACGGAGACGGTGCCGCCGAGCCTGGTGCTGATCACCATCGGCTCAGTGA
CCGGCATCTCCATTGCCGACCTGTTCACCGCCGGATTGATGCCGGGCATTGTGCTGGCACTCGTGCTCGGCCTGGTCGTG
TGGTGGCAGGCCCGCAAGAGCGGCAGCGCCTGCAGCGCGCGTGCCACGCGGGCCATGATCGGCAAGAGTCTCGTGGTGGC
ATTGCCCGCGCTCGCGCTGCCGTTCGTCGTGCGCGCCGCGGTGGTGGAGGGCGTGGCGACGGCGACGGAAGTGTCCACGA
TCGGCATCGTCTACGCGCTGATCGTCGGGCTGCTGGTGTACCGCAAGCTCGACCTCAGGCAACTGTGGCCCGCGCTCGTC
GATACGGCCGCCTTGTCTGGAGCGATCCTGCTGATCATCGGCACCGCGACCGGCATGGCCTGGTCGCTCACGCAGTCGGG
CTTCTCGGGTGACCTGGCAGCGGCCATGGCTCGGCTACCGGGGGGTGCGCCGGCTTTCATGGCGGTCTCGATCGTGGCCT
TCGTGCTGCTTGGCAGCGTGCTGGAAGGCATTCCCGCAATCGTGCTGTTCGGCCCGCTCCTGTTTCCGATCGCGCGCCAG
CTGGGCATCCATGACGTGCATTACTCGATGGTGGTCGTACTGGCCATGGGCATCGGCCTGTTCGCGCCGCCGTTCGGTGT
CGGCTACTACGCCGCCTGCGCGATCAGCCGTACCAAGCCTAGCGAGGGCGTGCGCCACATCTGGCGCTACATGACTTTCC
TGTTCATCGGCACCGTCGTCGTCGCGGCCGTGCCGTGGATCTCCACCGGTTTCCTCCATCACTGA

Upstream 100 bases:

>100_bases
GATCACGGTCACGGTCTACCCGCAACGTCTGGATCGCTTCGTCGACCCCGAAATTCAGGCCAACGTACTTGGCTTGCCGC
AGCAATGACGGAGGCGGGAC

Downstream 100 bases:

>100_bases
GCATCCCATGAAGTTCGCCGCCATCGTCGAATACGTAAACGAGCCTGAGCGCCTTGCGCAATTCCGGCCCGCCCATCGCG
CCTATCTGCAAGCGCTGTTG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSTHMVDINPPGIESHAGALSGGAPARTLRLADKALGVVSEVPAALLVVAEIGVLFSGVLSRYVLHTPLVWVDELASLLF
IWLIMLGAAVAFRRGSHMRMTALVDAAAPKWRGVFELVATVAALTWLVLVAHPAYEFASEEAAVTMPALDISNAWRAAAL
PLGIALILLMSVVRLLSTSSLRMVLVALVACAGVVGGLVLLQPALQELGNANLLVFFVGIVGLLVFTGVPIAFSFGLATF
GYLSLTTSTPTIVVIGRMDEGMSHLILLAVPMFVFLGVLIEMTSMARAMVQFLANLLGHIRGGLSYVLIGAMYLVSGISG
SKAADMAAVAPALFPEMKKRGADDGDMVALLAATGAQTETVPPSLVLITIGSVTGISIADLFTAGLMPGIVLALVLGLVV
WWQARKSGSACSARATRAMIGKSLVVALPALALPFVVRAAVVEGVATATEVSTIGIVYALIVGLLVYRKLDLRQLWPALV
DTAALSGAILLIIGTATGMAWSLTQSGFSGDLAAAMARLPGGAPAFMAVSIVAFVLLGSVLEGIPAIVLFGPLLFPIARQ
LGIHDVHYSMVVVLAMGIGLFAPPFGVGYYAACAISRTKPSEGVRHIWRYMTFLFIGTVVVAAVPWISTGFLHH

Sequences:

>Translated_634_residues
MSTHMVDINPPGIESHAGALSGGAPARTLRLADKALGVVSEVPAALLVVAEIGVLFSGVLSRYVLHTPLVWVDELASLLF
IWLIMLGAAVAFRRGSHMRMTALVDAAAPKWRGVFELVATVAALTWLVLVAHPAYEFASEEAAVTMPALDISNAWRAAAL
PLGIALILLMSVVRLLSTSSLRMVLVALVACAGVVGGLVLLQPALQELGNANLLVFFVGIVGLLVFTGVPIAFSFGLATF
GYLSLTTSTPTIVVIGRMDEGMSHLILLAVPMFVFLGVLIEMTSMARAMVQFLANLLGHIRGGLSYVLIGAMYLVSGISG
SKAADMAAVAPALFPEMKKRGADDGDMVALLAATGAQTETVPPSLVLITIGSVTGISIADLFTAGLMPGIVLALVLGLVV
WWQARKSGSACSARATRAMIGKSLVVALPALALPFVVRAAVVEGVATATEVSTIGIVYALIVGLLVYRKLDLRQLWPALV
DTAALSGAILLIIGTATGMAWSLTQSGFSGDLAAAMARLPGGAPAFMAVSIVAFVLLGSVLEGIPAIVLFGPLLFPIARQ
LGIHDVHYSMVVVLAMGIGLFAPPFGVGYYAACAISRTKPSEGVRHIWRYMTFLFIGTVVVAAVPWISTGFLHH
>Mature_633_residues
STHMVDINPPGIESHAGALSGGAPARTLRLADKALGVVSEVPAALLVVAEIGVLFSGVLSRYVLHTPLVWVDELASLLFI
WLIMLGAAVAFRRGSHMRMTALVDAAAPKWRGVFELVATVAALTWLVLVAHPAYEFASEEAAVTMPALDISNAWRAAALP
LGIALILLMSVVRLLSTSSLRMVLVALVACAGVVGGLVLLQPALQELGNANLLVFFVGIVGLLVFTGVPIAFSFGLATFG
YLSLTTSTPTIVVIGRMDEGMSHLILLAVPMFVFLGVLIEMTSMARAMVQFLANLLGHIRGGLSYVLIGAMYLVSGISGS
KAADMAAVAPALFPEMKKRGADDGDMVALLAATGAQTETVPPSLVLITIGSVTGISIADLFTAGLMPGIVLALVLGLVVW
WQARKSGSACSARATRAMIGKSLVVALPALALPFVVRAAVVEGVATATEVSTIGIVYALIVGLLVYRKLDLRQLWPALVD
TAALSGAILLIIGTATGMAWSLTQSGFSGDLAAAMARLPGGAPAFMAVSIVAFVLLGSVLEGIPAIVLFGPLLFPIARQL
GIHDVHYSMVVVLAMGIGLFAPPFGVGYYAACAISRTKPSEGVRHIWRYMTFLFIGTVVVAAVPWISTGFLHH

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=377, Percent_Identity=28.1167108753316, Blast_Score=142, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 66102; Mature: 65971

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHMVDINPPGIESHAGALSGGAPARTLRLADKALGVVSEVPAALLVVAEIGVLFSGVL
CCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYVLHTPLVWVDELASLLFIWLIMLGAAVAFRRGSHMRMTALVDAAAPKWRGVFELVAT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCHHHHHHHHHHH
VAALTWLVLVAHPAYEFASEEAAVTMPALDISNAWRAAALPLGIALILLMSVVRLLSTSS
HHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
LRMVLVALVACAGVVGGLVLLQPALQELGNANLLVFFVGIVGLLVFTGVPIAFSFGLATF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GYLSLTTSTPTIVVIGRMDEGMSHLILLAVPMFVFLGVLIEMTSMARAMVQFLANLLGHI
HHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGLSYVLIGAMYLVSGISGSKAADMAAVAPALFPEMKKRGADDGDMVALLAATGAQTET
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
VPPSLVLITIGSVTGISIADLFTAGLMPGIVLALVLGLVVWWQARKSGSACSARATRAMI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GKSLVVALPALALPFVVRAAVVEGVATATEVSTIGIVYALIVGLLVYRKLDLRQLWPALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTAALSGAILLIIGTATGMAWSLTQSGFSGDLAAAMARLPGGAPAFMAVSIVAFVLLGSV
HHHHHCCEEEEEEECCCCCEEEHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LEGIPAIVLFGPLLFPIARQLGIHDVHYSMVVVLAMGIGLFAPPFGVGYYAACAISRTKP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
SEGVRHIWRYMTFLFIGTVVVAAVPWISTGFLHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STHMVDINPPGIESHAGALSGGAPARTLRLADKALGVVSEVPAALLVVAEIGVLFSGVL
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYVLHTPLVWVDELASLLFIWLIMLGAAVAFRRGSHMRMTALVDAAAPKWRGVFELVAT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCHHHHHHHHHHH
VAALTWLVLVAHPAYEFASEEAAVTMPALDISNAWRAAALPLGIALILLMSVVRLLSTSS
HHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
LRMVLVALVACAGVVGGLVLLQPALQELGNANLLVFFVGIVGLLVFTGVPIAFSFGLATF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GYLSLTTSTPTIVVIGRMDEGMSHLILLAVPMFVFLGVLIEMTSMARAMVQFLANLLGHI
HHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGLSYVLIGAMYLVSGISGSKAADMAAVAPALFPEMKKRGADDGDMVALLAATGAQTET
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
VPPSLVLITIGSVTGISIADLFTAGLMPGIVLALVLGLVVWWQARKSGSACSARATRAMI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GKSLVVALPALALPFVVRAAVVEGVATATEVSTIGIVYALIVGLLVYRKLDLRQLWPALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTAALSGAILLIIGTATGMAWSLTQSGFSGDLAAAMARLPGGAPAFMAVSIVAFVLLGSV
HHHHHCCEEEEEEECCCCCEEEHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LEGIPAIVLFGPLLFPIARQLGIHDVHYSMVVVLAMGIGLFAPPFGVGYYAACAISRTKP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
SEGVRHIWRYMTFLFIGTVVVAAVPWISTGFLHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]