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The map label for this gene is infA2

Identifier: 73539011

GI number: 73539011

Start: 1928636

End: 1928857

Strand: Direct

Name: infA2

Synonym: Reut_B5188

Alternate gene names: 73539011

Gene position: 1928636-1928857 (Clockwise)

Preceding gene: 73539010

Following gene: 73539012

Centisome position: 70.75

GC content: 53.6

Gene sequence:

>222_bases
GTGGCAAAAGAAGAACTGGTGGAATTTGGCGGAAAGGTTTCGGAAGTCCTTCCGGATAACCGCTTTCGCGTCACCCTGGA
GAATGGCTTCGAGGTCTGGGCTTACTCGTCTGGCCGGCTCAAGAGGAATCGCATACGGATTCTTGCCGGGGATCGTGTTA
CGCTCGAAATGTCGCCATACGATCTGACAAAGGGGCGCATCAACTATCGCCACAAGTTCTGA

Upstream 100 bases:

>100_bases
GCGCAGGGGAAAGCGCAGTGGCACACCTACGCCTGCAACCATTCCCGCATCGGCATCCCATGCTATCGCGTGGCACTCGC
TAAAGCAGAAAGGAGCATCC

Downstream 100 bases:

>100_bases
GCGAATGCGGCTTTTCTGCGTGTCGAAATGGCGATCACTGTTGGTGCCACCTCGGAATAGAACCATTTTTTTGTTGGTCC
AGGTACGAGTGAGAGCACAA

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MAKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPYDLTKGRINYRHKF

Sequences:

>Translated_73_residues
MAKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPYDLTKGRINYRHKF
>Mature_72_residues
AKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPYDLTKGRINYRHKF

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=55.5555555555556, Blast_Score=87, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF12_CUPPJ (Q46QQ0)

Other databases:

- EMBL:   CP000091
- RefSeq:   YP_299378.1
- ProteinModelPortal:   Q46QQ0
- SMR:   Q46QQ0
- GeneID:   3613187
- GenomeReviews:   CP000091_GR
- KEGG:   reu:Reut_B5188
- NMPDR:   fig|264198.3.peg.6163
- HOGENOM:   HBG286099
- OMA:   EFSPYDL
- ProtClustDB:   PRK12442
- BioCyc:   REUT264198:REUT_B5188-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8562; Mature: 8431

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPY
CCHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEECCCCEECCEEEEEECCEEEEEECCC
DLTKGRINYRHKF
CCCCCEEEEEECC
>Mature Secondary Structure 
AKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPY
CHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEECCCCEECCEEEEEECCEEEEEECCC
DLTKGRINYRHKF
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA