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The map label for this gene is CYP102A1 [H]

Identifier: 73538989

GI number: 73538989

Start: 1904901

End: 1907111

Strand: Reverse

Name: CYP102A1 [H]

Synonym: Reut_B5165

Alternate gene names: 73538989

Gene position: 1907111-1904901 (Counterclockwise)

Preceding gene: 73538990

Following gene: 73538988

Centisome position: 69.96

GC content: 64.27

Gene sequence:

>2211_bases
ATGTTACGCAAGCTCCATTCAATCCCCGGTCTCATTGCTGCATTGCTGATGACGATCGTCGCCTTGGCAGGCGCCGCGCT
TTCGGTGAATCCGGCACTTGAGCAGGCAAGTGCCGTTCGCCCGAGCCTCGCTCCTCTTAGCGTTGCAACGCTAGCCAGCC
GCGTGAGCGCCGCGACGCCCGACATCGAAACTCTCACACGTCGGCCGTCAGGGGTGATCATCGCGCACTACCAGGCCGGG
GGCCAACAGCGTGCATCGATCATCGATCCCGCTACTGGCAAGGCTATCGGCGACTATCGCCCCTCGGCTGTCGAGCGTTG
GCTGAAGAACCTGCACCGCAAGCTCTTTCTTGGCGACGCTGGCCGGATCGCAACCGGTGCGACTGCTGCCCTCATGCTGT
TCGCAGCGTTGTCCGGGCTTGTATTGCTCGCACGCCGGATGGGCGGGTGGTCGCGTATTTTGGCCCCGATCCGGGGTGAC
GGGTTGCAGCGGTTGCATAACGAAACTGCGCGCGCTGCGCTTGCCGGCCTCACGCTGTCGGCGATAACCGGGGTCTTCAT
GTCGTTGACGACGTTCGGCGTGATTCCCGAAGGCGGCGCGCAGGAACCCGCCCTCAGCGTTCCGGCAATCACCACACCCC
CGATGCCGTTGCGGCAGATGCCCGCACTGGCAATAGATGTCTCCAGTCTGCGCCAGCTGACGTTTGCCAACGCGGCCGAC
CCAACCAGCCTCATCGAGGTGAATACGACGGATGGCATCGGTTATGTCGATCCATCGTCAGGCAGATGGCTTGCCTTTCA
GCCGGCCGACGCCTGGCAACGTGCGCATGGTGTTGTCCGCATGCTGCACACGGGCGAAGGGCTATGGTGGCTCGGGCTGA
TCCTCGGCGCATCGTCGGCGTCGGTGCCGTTGCTGGCCGCAACCGGTCTGCTGCTGTGGCTGCGTCGTCGACGGGCCATG
CCGAAGCTCGCTGGGAACGTGCCGGCACGCGACGCGGATACCGTGTTGCTGGTGGGCACCGAGGGCAATAGCACGTGGGG
CTTTGCTTCGGCGCTGCATGCAGCGCTGACCCGGGCTGGCCTTCGCGTGCATGTAGCGCCGATGAACGATTTTGCAGCCG
GCTACCGCAGCCTGCGGTATCTGCTGGTCCTGACTGCGACCTACGGTGACGGCGATGCACCGGAGAGCGCTGTGCGATTC
CTGCCGAAGCTCGAGCGCCTGACGATCCCCGGCGGGGTAGCGTTCGGGGTCTTGGGCTTCGGCGACCGCCAGTTTCCTCA
TTTTTGCGGCTATGCGCGAACGGTTCATGACGCACTGACCGCCAGGGGGCTGGAAGCACTGACCGATCCGGGCACGGTTG
ACCGGCAGTCTGAACCCGAATTCCGGCAGTGGTGTACGGGGCTCGCCGAAAGGCTCGGCGTATCGCTCGATATCCGCTAT
ACGCCATTGCTGCCGCCCACGATACCGCTCAAGCTCGTCTCACGTGACGACTATGGTGGGGATCCGGAGGACATGACTTC
GGTGTTGCGCTTCATGCCTGCCGAGGGGGCAAGATCCTGGGCCACCCTGCTACGGCCGCGGCTGCCCCGGTTCGGGACGG
GGGATCTGCTCGGCGTCGTGCCACCGGGTGCTACCTCGCCCCGGTACTACTCGCTCGCGAGCGCGACAGCGGACGGCCTG
GCCGAGATCTGCGTGCGGCGTCATCCGAACGGCGTGTGCTCCAGGTATCTCACAGGCCTGCAGCCAGGCGACACGATTAA
GGCATTCATGCGGCCGCACGCGAGCTTTCGGCCGGGCGCGGGAAACGCTCCTTTAATCCTGATCGGGGCCGGTACCGGGA
TTGGTCCGCTGATCGGCTTCATCCGGCACAACGGGGCCCGCCGTCCGATGCACCTGTATTTTGGTGCGCGCAATGCTGAC
GATGGTTTCCTGTACCGCGACGAACTCAGGGACCTGGTAGCCGACCGGCGGCTGCAGGCACTCACGACTGCCTTCTCACG
CTCCGGTAGTCGGAGTTATGTGCAGGACCGCCTTGTCGCCGATGCAGTGAGCCTGCGCACCTTGCTTACTCACGGTGCGC
AAATCATGGTGTGCGGTGGCCGAAGGATGGCGGAGGGGGTCGCACAGGCGTGGGAACGCATTTTGACGGGTACCGGCTTG
TCCGTCGCACAACTGAGAGCACAGGGACGTTATGTCGAAGATGTCTATTGA

Upstream 100 bases:

>100_bases
CCGCTGACCTCCTCGGGCGCGAACAAGACATTCAAGGGGAGTGGCAATGTGAAGTCGTTCCGCTATTCACTGTAACCAGG
GGCAGGCGAGAAGGTGACCG

Downstream 100 bases:

>100_bases
GGGGGCGCCTGACCTGCAGCTCAAGCGCTTCCGGGTGACCGGCGCGACGATGGGCACGCGGTACTCTGCGACGTTCCACG
CGTCCCCGGAGACCGATGAA

Product: flavodoxin/nitric oxide synthase

Products: NA

Alternate protein names: Cytochrome P450(BM-3); Cytochrome P450BM-3; Cytochrome P450 102; NADPH--cytochrome P450 reductase [H]

Number of amino acids: Translated: 736; Mature: 736

Protein sequence:

>736_residues
MLRKLHSIPGLIAALLMTIVALAGAALSVNPALEQASAVRPSLAPLSVATLASRVSAATPDIETLTRRPSGVIIAHYQAG
GQQRASIIDPATGKAIGDYRPSAVERWLKNLHRKLFLGDAGRIATGATAALMLFAALSGLVLLARRMGGWSRILAPIRGD
GLQRLHNETARAALAGLTLSAITGVFMSLTTFGVIPEGGAQEPALSVPAITTPPMPLRQMPALAIDVSSLRQLTFANAAD
PTSLIEVNTTDGIGYVDPSSGRWLAFQPADAWQRAHGVVRMLHTGEGLWWLGLILGASSASVPLLAATGLLLWLRRRRAM
PKLAGNVPARDADTVLLVGTEGNSTWGFASALHAALTRAGLRVHVAPMNDFAAGYRSLRYLLVLTATYGDGDAPESAVRF
LPKLERLTIPGGVAFGVLGFGDRQFPHFCGYARTVHDALTARGLEALTDPGTVDRQSEPEFRQWCTGLAERLGVSLDIRY
TPLLPPTIPLKLVSRDDYGGDPEDMTSVLRFMPAEGARSWATLLRPRLPRFGTGDLLGVVPPGATSPRYYSLASATADGL
AEICVRRHPNGVCSRYLTGLQPGDTIKAFMRPHASFRPGAGNAPLILIGAGTGIGPLIGFIRHNGARRPMHLYFGARNAD
DGFLYRDELRDLVADRRLQALTTAFSRSGSRSYVQDRLVADAVSLRTLLTHGAQIMVCGGRRMAEGVAQAWERILTGTGL
SVAQLRAQGRYVEDVY

Sequences:

>Translated_736_residues
MLRKLHSIPGLIAALLMTIVALAGAALSVNPALEQASAVRPSLAPLSVATLASRVSAATPDIETLTRRPSGVIIAHYQAG
GQQRASIIDPATGKAIGDYRPSAVERWLKNLHRKLFLGDAGRIATGATAALMLFAALSGLVLLARRMGGWSRILAPIRGD
GLQRLHNETARAALAGLTLSAITGVFMSLTTFGVIPEGGAQEPALSVPAITTPPMPLRQMPALAIDVSSLRQLTFANAAD
PTSLIEVNTTDGIGYVDPSSGRWLAFQPADAWQRAHGVVRMLHTGEGLWWLGLILGASSASVPLLAATGLLLWLRRRRAM
PKLAGNVPARDADTVLLVGTEGNSTWGFASALHAALTRAGLRVHVAPMNDFAAGYRSLRYLLVLTATYGDGDAPESAVRF
LPKLERLTIPGGVAFGVLGFGDRQFPHFCGYARTVHDALTARGLEALTDPGTVDRQSEPEFRQWCTGLAERLGVSLDIRY
TPLLPPTIPLKLVSRDDYGGDPEDMTSVLRFMPAEGARSWATLLRPRLPRFGTGDLLGVVPPGATSPRYYSLASATADGL
AEICVRRHPNGVCSRYLTGLQPGDTIKAFMRPHASFRPGAGNAPLILIGAGTGIGPLIGFIRHNGARRPMHLYFGARNAD
DGFLYRDELRDLVADRRLQALTTAFSRSGSRSYVQDRLVADAVSLRTLLTHGAQIMVCGGRRMAEGVAQAWERILTGTGL
SVAQLRAQGRYVEDVY
>Mature_736_residues
MLRKLHSIPGLIAALLMTIVALAGAALSVNPALEQASAVRPSLAPLSVATLASRVSAATPDIETLTRRPSGVIIAHYQAG
GQQRASIIDPATGKAIGDYRPSAVERWLKNLHRKLFLGDAGRIATGATAALMLFAALSGLVLLARRMGGWSRILAPIRGD
GLQRLHNETARAALAGLTLSAITGVFMSLTTFGVIPEGGAQEPALSVPAITTPPMPLRQMPALAIDVSSLRQLTFANAAD
PTSLIEVNTTDGIGYVDPSSGRWLAFQPADAWQRAHGVVRMLHTGEGLWWLGLILGASSASVPLLAATGLLLWLRRRRAM
PKLAGNVPARDADTVLLVGTEGNSTWGFASALHAALTRAGLRVHVAPMNDFAAGYRSLRYLLVLTATYGDGDAPESAVRF
LPKLERLTIPGGVAFGVLGFGDRQFPHFCGYARTVHDALTARGLEALTDPGTVDRQSEPEFRQWCTGLAERLGVSLDIRY
TPLLPPTIPLKLVSRDDYGGDPEDMTSVLRFMPAEGARSWATLLRPRLPRFGTGDLLGVVPPGATSPRYYSLASATADGL
AEICVRRHPNGVCSRYLTGLQPGDTIKAFMRPHASFRPGAGNAPLILIGAGTGIGPLIGFIRHNGARRPMHLYFGARNAD
DGFLYRDELRDLVADRRLQALTTAFSRSGSRSYVQDRLVADAVSLRTLLTHGAQIMVCGGRRMAEGVAQAWERILTGTGL
SVAQLRAQGRYVEDVY

Specific function: Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is re

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI40254422, Length=228, Percent_Identity=35.0877192982456, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI24041029, Length=241, Percent_Identity=32.3651452282158, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI10835173, Length=230, Percent_Identity=32.6086956521739, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI127139033, Length=224, Percent_Identity=33.0357142857143, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI169790956, Length=213, Percent_Identity=30.0469483568075, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI169790958, Length=213, Percent_Identity=30.0469483568075, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1789123, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554134, Length=192, Percent_Identity=34.8958333333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566446, Length=167, Percent_Identity=31.1377245508982, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325305, Length=171, Percent_Identity=29.8245614035088, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321832, Length=171, Percent_Identity=33.9181286549708, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583543, Length=187, Percent_Identity=34.7593582887701, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI78706876, Length=187, Percent_Identity=34.7593582887701, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI78706872, Length=187, Percent_Identity=34.7593582887701, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582192, Length=225, Percent_Identity=29.7777777777778, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137192, Length=225, Percent_Identity=29.7777777777778, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023206
- InterPro:   IPR001128
- InterPro:   IPR015702
- InterPro:   IPR017972
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1; PF00067 p450 [H]

EC number: =1.14.14.1; =1.6.2.4 [H]

Molecular weight: Translated: 78609; Mature: 78609

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKLHSIPGLIAALLMTIVALAGAALSVNPALEQASAVRPSLAPLSVATLASRVSAATP
CCCHHHCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
DIETLTRRPSGVIIAHYQAGGQQRASIIDPATGKAIGDYRPSAVERWLKNLHRKLFLGDA
CHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCC
GRIATGATAALMLFAALSGLVLLARRMGGWSRILAPIRGDGLQRLHNETARAALAGLTLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AITGVFMSLTTFGVIPEGGAQEPALSVPAITTPPMPLRQMPALAIDVSSLRQLTFANAAD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHEEEHHHHHHHHHCCCCC
PTSLIEVNTTDGIGYVDPSSGRWLAFQPADAWQRAHGVVRMLHTGEGLWWLGLILGASSA
CCEEEEEECCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
SVPLLAATGLLLWLRRRRAMPKLAGNVPARDADTVLLVGTEGNSTWGFASALHAALTRAG
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
LRVHVAPMNDFAAGYRSLRYLLVLTATYGDGDAPESAVRFLPKLERLTIPGGVAFGVLGF
CEEEEECCHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHEECCCCHHEEEECC
GDRQFPHFCGYARTVHDALTARGLEALTDPGTVDRQSEPEFRQWCTGLAERLGVSLDIRY
CCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEE
TPLLPPTIPLKLVSRDDYGGDPEDMTSVLRFMPAEGARSWATLLRPRLPRFGTGDLLGVV
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEC
PPGATSPRYYSLASATADGLAEICVRRHPNGVCSRYLTGLQPGDTIKAFMRPHASFRPGA
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCC
GNAPLILIGAGTGIGPLIGFIRHNGARRPMHLYFGARNADDGFLYRDELRDLVADRRLQA
CCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHH
LTTAFSRSGSRSYVQDRLVADAVSLRTLLTHGAQIMVCGGRRMAEGVAQAWERILTGTGL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCC
SVAQLRAQGRYVEDVY
HHHHHHHCCCCHHCCC
>Mature Secondary Structure
MLRKLHSIPGLIAALLMTIVALAGAALSVNPALEQASAVRPSLAPLSVATLASRVSAATP
CCCHHHCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
DIETLTRRPSGVIIAHYQAGGQQRASIIDPATGKAIGDYRPSAVERWLKNLHRKLFLGDA
CHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCC
GRIATGATAALMLFAALSGLVLLARRMGGWSRILAPIRGDGLQRLHNETARAALAGLTLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AITGVFMSLTTFGVIPEGGAQEPALSVPAITTPPMPLRQMPALAIDVSSLRQLTFANAAD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHEEEHHHHHHHHHCCCCC
PTSLIEVNTTDGIGYVDPSSGRWLAFQPADAWQRAHGVVRMLHTGEGLWWLGLILGASSA
CCEEEEEECCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
SVPLLAATGLLLWLRRRRAMPKLAGNVPARDADTVLLVGTEGNSTWGFASALHAALTRAG
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
LRVHVAPMNDFAAGYRSLRYLLVLTATYGDGDAPESAVRFLPKLERLTIPGGVAFGVLGF
CEEEEECCHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHEECCCCHHEEEECC
GDRQFPHFCGYARTVHDALTARGLEALTDPGTVDRQSEPEFRQWCTGLAERLGVSLDIRY
CCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEE
TPLLPPTIPLKLVSRDDYGGDPEDMTSVLRFMPAEGARSWATLLRPRLPRFGTGDLLGVV
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEC
PPGATSPRYYSLASATADGLAEICVRRHPNGVCSRYLTGLQPGDTIKAFMRPHASFRPGA
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCC
GNAPLILIGAGTGIGPLIGFIRHNGARRPMHLYFGARNADDGFLYRDELRDLVADRRLQA
CCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHH
LTTAFSRSGSRSYVQDRLVADAVSLRTLLTHGAQIMVCGGRRMAEGVAQAWERILTGTGL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCC
SVAQLRAQGRYVEDVY
HHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544578; 1727637; 8342039; 9033595; 10051560; 11695892 [H]